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Showing 9985 to 9996 of 47014 entries
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Afatinib vs erlotinib for second-line treatment of Chinese patients with advanced squamous cell carcinoma of the lung.

OncoTargets and therapy

Lu S, Li W, Zhou C, Hu CP, Qin S, Cheng G, Feng J, Wang J, Cseh A, Peil B, Gibson N, Ehrnrooth E, Zhang L.
PMID: 30573970
Onco Targets Ther. 2018 Nov 30;11:8565-8573. doi: 10.2147/OTT.S161506. eCollection 2018.

BACKGROUND: The global Phase III LUX-Lung 8 trial (ClinicalTrials.gov: NCT01523587) identified significant improvements in progression-free survival (PFS), overall survival (OS), and patient-reported outcomes (PROs) with second-line afatinib vs erlotinib in patients with advanced squamous cell carcinoma (SCC) of the...

The Carcinogenic Role of the Notch Signaling Pathway in the Development of Hepatocellular Carcinoma.

Journal of Cancer

Huang Q, Li J, Zheng J, Wei A.
PMID: 31031867
J Cancer. 2019 Feb 26;10(6):1570-1579. doi: 10.7150/jca.26847. eCollection 2019.

The Notch signaling pathway, known to be a highly conserved signaling pathway in embryonic development and adult tissue homeostasis, participates in cell fate decisions that include cellular differentiation, cell survival and cell death. However, other studies have shown that...

Association of SPOP Expression with the Immune Response to .

Animals : an open access journal from MDPI

Wang F, Li Q, Wang Q, Zheng M, Wen J, Zhao G.
PMID: 32075044
Animals (Basel). 2020 Feb 14;10(2). doi: 10.3390/ani10020307.

Salmonellosis is a zoonosis that is not only harmful to the health of poultry but also poses a threat to human health. Although many measures have been put in place to reduce morbidity, they have not provided satisfactory results....

ClinEpiDB: an open-access clinical epidemiology database resource encouraging online exploration of complex studies.

Gates open research

Ruhamyankaka E, Brunk BP, Dorsey G, Harb OS, Helb DA, Judkins J, Kissinger JC, Lindsay B, Roos DS, San EJ, Stoeckert CJ, Zheng J, Tomko SS.
PMID: 32047873
Gates Open Res. 2019 Nov 25;3:1661. doi: 10.12688/gatesopenres.13087.1. eCollection 2019.

The concept of open data has been gaining traction as a mechanism to increase data use, ensure that data are preserved over time, and accelerate discovery. While epidemiology data sets are increasingly deposited in databases and repositories, barriers to...

Does Inside Equal Outside? Relations Between Older Adults' Implicit and Explicit Aging Attitudes and Self-Esteem.

Frontiers in psychology

Chen J, Zheng K, Xia W, Wang Q, Liao Z, Zheng Y.
PMID: 30546332
Front Psychol. 2018 Nov 22;9:2313. doi: 10.3389/fpsyg.2018.02313. eCollection 2018.

Attitudes toward one's own aging and self-esteem are crucial variables in predicting older adults' physical and mental health and can significantly affect their will to live, cognitive judgement and acceptance of medical treatment. However, little is known about the...

Combined ultrasound/computed tomography guidance in percutaneous radiofrequency ablation after transarterial chemoembolization for hepatocellular carcinoma in the hepatic dome.

Cancer management and research

Kan X, Wang Y, Han P, Yao Q, Qian K, Xiong B, Zheng C.
PMID: 31616188
Cancer Manag Res. 2019 Aug 15;11:7751-7757. doi: 10.2147/CMAR.S212127. eCollection 2019.

PURPOSE: To assess the value of the combined ultrasound (US)/computed tomography (CT) guidance (US guidance was firstly used for puncture with the electrode needle to the site close to the tumor, and subsequently, CT guidance was used for precise...

Hepatic Arterial Infusion Oxaliplatin Plus Oral S-1 Chemotherapy in Gastric Cancer with Unresectable Liver Metastases: A Case Series and Literature Review.

Cancer management and research

Wang K, Zhang X, Wei J, Xu Y, Liu Q, Xie J, Yuan L, Sun Z, Tan S, Zhang L, Liu B, Yang Y.
PMID: 32104068
Cancer Manag Res. 2020 Feb 07;12:863-870. doi: 10.2147/CMAR.S233123. eCollection 2020.

OBJECTIVE: The use of hepatic artery infusion (HAI) as a regional therapy against liver metastasis has rarely been reported in gastric cancer. This study aimed to evaluate the efficacy and safety of HAI oxaliplatin plus oral S-1 chemotherapy in...

Deep desulfurization of fuels using supported ionic liquid-polyoxometalate hybrid as catalyst: A comparison of different types of ionic liquids.

Journal of hazardous materials

Gao Y, Cheng L, Gao R, Hu G, Zhao J.
PMID: 32634664
J Hazard Mater. 2021 Jan 05;401:123267. doi: 10.1016/j.jhazmat.2020.123267. Epub 2020 Jun 22.

In this work, polyoxometalates-based monomer ionic liquid, dimer ionic liquid and polyionic liquid were designed and prepared. Then supported catalysts were synthesized by loading polyoxometalate derivatives on the surface of graphene oxide (GO). The catalysts before and after loading...

Differential roles of p38 MAPK and ERK1/2 in angiopoietin-2-mediated rat pulmonary microvascular endothelial cell apoptosis induced by lipopolysaccharide.

Experimental and therapeutic medicine

Li S, Zhong M, Yuan Y, Zhang L.
PMID: 30546397
Exp Ther Med. 2018 Dec;16(6):4729-4736. doi: 10.3892/etm.2018.6810. Epub 2018 Oct 01.

Angiopoietin-2 (Ang-2) is a Tie-2 ligand that destabilizes vascular structures, enhances vascular permeability and induces vascular regression and endothelial cell apoptosis. Although there is evidence for the involvement of the Ang/Tie2 axis in acute lung injury (ALI), the underlying...

A CEP Peptide Receptor-like Kinase Regulates Auxin Biosynthesis and Ethylene Signaling to Coordinate Root Growth and Symbiotic Nodulation in Medicago truncatula.

The Plant cell

Zhu F, Deng J, Chen H, Liu P, Zheng L, Ye Q, Li R, Brault M, Wen J, Frugier F, Dong J, Wang T.
PMID: 32586912
Plant Cell. 2020 Jun 25; doi: 10.1105/tpc.19.00428. Epub 2020 Jun 25.

Because of the high energy consumed during symbiotic nitrogen fixation, legumes must balance growth and symbiotic nodulation. Both lateral roots and nodules form on the root system and the developmental coordination of these organs according to reduced nitrogen (N)...

Stabilizing Lithium into Cross-Stacked Nanotube Sheets with an Ultra-High Specific Capacity for Lithium Oxygen Batteries.

Angewandte Chemie (International ed. in English)

Ye L, Liao M, Sun H, Yang Y, Tang C, Zhao Y, Wang L, Xu Y, Zhang L, Wang B, Xu F, Sun X, Zhang Y, Dai H, Bruce PG, Peng H.
PMID: 30575248
Angew Chem Int Ed Engl. 2019 Feb 18;58(8):2437-2442. doi: 10.1002/anie.201814324. Epub 2019 Jan 21.

Although lithium-oxygen batteries possess a high theoretical energy density and are considered as promising candidates for next-generation power systems, the enhancement of safety and cycling efficiency of the lithium anodes while maintaining the high energy storage capability remains difficult....

Intestinal Surgery Contributes to Acute Cerebellar Ataxia Through Gut Brain Axis.

Frontiers in neurology

Yu J, Fan Y, Wang L, Huang Y, Xia J, Ding L, Wu CF, Lu X, Ma G, Kim S, Zheng G, Guo H, Zhang G.
PMID: 31616359
Front Neurol. 2019 Sep 20;10:995. doi: 10.3389/fneur.2019.00995. eCollection 2019.

No abstract available.

Showing 9985 to 9996 of 47014 entries