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Showing 925 to 929 of 929 entries
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Adaptive sample size determination for the development of clinical prediction models.

Diagnostic and prognostic research

Christodoulou E, van Smeden M, Edlinger M, Timmerman D, Wanitschek M, Steyerberg EW, Van Calster B.
PMID: 33745449
Diagn Progn Res. 2021 Mar 22;5(1):6. doi: 10.1186/s41512-021-00096-5.

BACKGROUND: We suggest an adaptive sample size calculation method for developing clinical prediction models, in which model performance is monitored sequentially as new data comes in.METHODS: We illustrate the approach using data for the diagnosis of ovarian cancer (n...

Antifibrotic factor KLF4 is repressed by the miR-10/TFAP2A/TBX5 axis in dermal fibroblasts: insights from twins discordant for systemic sclerosis.

Annals of the rheumatic diseases

Malaab M, Renaud L, Takamura N, Zimmerman KD, da Silveira WA, Ramos PS, Haddad S, Peters-Golden M, Penke LR, Wolf B, Hardiman G, Langefeld CD, Medsger TA, Feghali-Bostwick CA.
PMID: 34750102
Ann Rheum Dis. 2022 Feb;81(2):268-277. doi: 10.1136/annrheumdis-2021-221050. Epub 2021 Nov 08.

OBJECTIVES: Systemic sclerosis (SSc) is a complex disease of unknown aetiology in which inflammation and fibrosis lead to multiple organ damage. There is currently no effective therapy that can halt the progression of fibrosis or reverse it, thus studies...

Crisis Interventions in Schools: A Systematic Review.

Journal of school violence

Sokol RL, Heinze J, Doan J, Normand M, Grodzinski A, Pomerantz N, Scott BA, Gaswirth M, Zimmerman M.
PMID: 33776599
J Sch Violence. 2021;20(2):241-260. doi: 10.1080/15388220.2021.1879098. Epub 2021 Feb 23.

This systematic review synthesizes research on school-based crisis intervention protocols, descriptions, and evaluations. We performed a comprehensive literature search, and 60 studies met the inclusion criteria for this review. We found an overwhelming lack of evaluation studies (n=3), suggesting...

Child Domestic Work, Violence, and Health Outcomes: A Rapid Systematic Review.

International journal of environmental research and public health

Thi AM, Zimmerman C, Pocock NS, Chan CW, Ranganathan M.
PMID: 35010705
Int J Environ Res Public Health. 2021 Dec 31;19(1). doi: 10.3390/ijerph19010427.

This rapid systematic review describes violence and health outcomes among child domestic workers (CDWs) taken from 17 studies conducted in low- and middle-income countries. Our analysis estimated the median reported rates of violence in CDWs aged 5-17-year-olds to be...

A Quantitative Linguistic Analysis of National Institutes of Health R01 Application Critiques From Investigators at One Institution.

Carnes M, Kaatz A, Magua W, Zimmerman DR.
UIID-AD: 1331
2015;90:69-75. doi: 10.1097/acm.0000000000000442.

Purpose Career advancement in academic medicine often hinges on the ability to garner research funds. The National Institutes of Health's (NIH's) R01 award is the "gold standard" of an independent research program. Studies show inconsistencies in R01 reviewers' scoring...

Showing 925 to 929 of 929 entries