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Showing 313 to 321 of 321 entries
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The role of factor XIII in surgery for advanced stage of epithelial ovarian cancer.

Archives of gynecology and obstetrics

Yazdian M, Groeben H, Ataseven B, Schneider S, Baert T, Bommert M, Traut A, Elfers-Wassenhoven A, Brüß U, Schwameis R, du Bois A, Wagner U, Harter P.
PMID: 34724570
Arch Gynecol Obstet. 2021 Nov 01; doi: 10.1007/s00404-021-06308-z. Epub 2021 Nov 01.

INTRODUCTION: Hereditary factor (F) XIII-deficiency is a known risk factor for postoperative complications, but data of acquired FXIII-deficiency in malignancies are limited. Therefore, we evaluated the role of acquired FXIII-deficiency in surgery for advanced epithelial ovarian cancer (EOC).MATERIALS AND...

Qualitative and Quantitative Detection of SARS-CoV-2 Antibodies from Dried Blood Spots.

Clinical biochemistry

Omosule CL, Conklin J, Seck S, Howell R, Hock KG, Ballman C, Freeman J, Du Toit L, Dubberke E, Farnsworth CW.
PMID: 34990593
Clin Biochem. 2022 Jan 03; doi: 10.1016/j.clinbiochem.2021.12.012. Epub 2022 Jan 03.

INTRODUCTION: Dried blood spot (DBS) sampling is a minimally invasive method for specimen collection with potential multifaceted uses, particularly for serosurveillance of previous SARS-CoV-2 infection. In this study, we assessed DBS as a potential specimen type for assessing IgG...

Randomized Trial of Cytoreductive Surgery for Relapsed Ovarian Cancer.

The New England journal of medicine

Harter P, Sehouli J, Vergote I, Ferron G, Reuss A, Meier W, Greggi S, Mosgard BJ, Selle F, Guyon F, Pomel C, Lécuru F, Zang R, Avall-Lundqvist E, Kim JW, Ponce J, Raspagliesi F, Kristensen G, Classe JM, Hillemanns P, Jensen P, Hasenburg A, Ghaem-Maghami S, Mirza MR, Lund B, Reinthaller A, Santaballa A, Olaitan A, Hilpert F, du Bois A.
PMID: 34874631
N Engl J Med. 2021 Dec 02;385(23):2123-2131. doi: 10.1056/NEJMoa2103294.

BACKGROUND: Treatment for patients with recurrent ovarian cancer has been mainly based on systemic therapy. The role of secondary cytoreductive surgery is unclear.METHODS: We randomly assigned patients with recurrent ovarian cancer who had a first relapse after a platinum-free...

Escape from recognition of SARS-CoV-2 Beta variant spike epitopes but overall preservation of T cell immunity.

Science translational medicine

Riou C, Keeton R, Moyo-Gwete T, Hermanus T, Kgagudi P, Baguma R, Valley-Omar Z, Smith M, Tegally H, Doolabh D, Iranzadeh A, Tyers L, Mutavhatsindi H, Tincho MB, Benede N, Marais G, Chinhoyi LR, Mennen M, Skelem S, du Bruyn E, Stek C, de Oliveira T, Williamson C, Moore PL, Wilkinson RJ, Ntusi NAB, Burgers WA, Abrahams F, Ayres F, du Toit E, Goliath RT, Hanekom W, Hardie D, Hsiao NY, Kloverpris H, Korsman S, Lakay F, Lambson B, Leslie A, Makhado Z, Maseko M, Mhlanga D, Naidoo M, Ndhlovu Z, Ngomti A, Oosthuysen B, Ruzive S, Sigal A, Smith T, Valley-Omar Z, van der Westhuizen D, Zvinairo K.
PMID: 34931886
Sci Transl Med. 2021 Dec 21;eabj6824. Epub 2021 Dec 21.

[Figure: see text].

Root submergence technique as a partial extraction therapy to preserve the alveolar ridge tissues: A systematic review and appraisal of the literature.

The Journal of prosthetic dentistry

Du Toit J, Salama M, Gluckman H, Nagy K.
PMID: 34750013
J Prosthet Dent. 2021 Nov 05; doi: 10.1016/j.prosdent.2021.08.009. Epub 2021 Nov 05.

STATEMENT OF PROBLEM: As socket grafting with commercially available biomaterials has become popular, reports of the root submergence technique for ridge preservation have decreased. A systematic review of this partial extraction therapy is lacking.PURPOSE: The purpose of this systematic...

Effect of chronic restraint stress and western-diet feeding on colonic regulatory gene expression in mice.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

Hatton-Jones KM, du Toit EF, Cox AJ.
PMID: 34825433
Neurogastroenterol Motil. 2021 Nov 26;e14300. doi: 10.1111/nmo.14300. Epub 2021 Nov 26.

BACKGROUND: Diet-induced obesity (DIO) and psychological stress are significant independent regulators of gastrointestinal physiology; however, our understanding of how these two disorders influence the host-microbe interface is still poorly characterized. The aim of this study was to assess the...

Cell-Free-DNA-Based Copy Number Index Score in Epithelial Ovarian Cancer-Impact for Diagnosis and Treatment Monitoring.

Cancers

Braicu EI, du Bois A, Sehouli J, Beck J, Prader S, Kulbe H, Eiben B, Harter P, Traut A, Pietzner K, Glaubitz R, Ataseven B, Chekerov R, Keck C, Winkler T, Heikaus S, Gellendin P, Schütz E, Heitz F.
PMID: 35008332
Cancers (Basel). 2021 Dec 30;14(1). doi: 10.3390/cancers14010168.

BACKGROUND: Chromosomal instability, a hallmark of cancer, results in changes in the copy number state. These deviant copy number states can be detected in the cell-free DNA (cfDNA) and provide a quantitative measure of the ctDNA levels by converting...

Is Haploidentical Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide Feasible in Sub-Saharan Africa?.

Transplantation and cellular therapy

du Toit JR, Mcdonald A, Brittain D, Cass M, Thomson J, Oosthuizen J, du Toit C, Seftel M, Louw VJ, Verburgh E.
PMID: 34478910
Transplant Cell Ther. 2021 Dec;27(12):1002.e1-1002.e8. doi: 10.1016/j.jtct.2021.08.018. Epub 2021 Aug 31.

Identifying a suitable volunteer unrelated donor (UD) in South Africa is challenging due to the highly diverse ethnic groups and mixed-race populations in this region. Haploidentical hematopoietic cell transplantation (haploHCT) is thus an attractive procedure for patients with high-risk...

SARS-CoV-2 incidence, transmission and reinfection in a rural and an urban setting: results of the PHIRST-C cohort study, South Africa, 2020-2021.

medRxiv : the preprint server for health sciences

Cohen C, Kleynhans J, von Gottberg A, McMorrow ML, Wolter N, Bhiman JN, Moyes J, du Plessis M, Carrim M, Buys A, Martinson NA, Kahn K, Tollman S, Lebina L, Wafawanaka F, du Toit J, Gómez-Olivé FX, Dawood FS, Mkhencele T, Sun K, Viboud C, Tempia S.
PMID: 34909794
medRxiv. 2021 Dec 04; doi: 10.1101/2021.07.20.21260855.

No abstract available.

Showing 313 to 321 of 321 entries