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Showing 49 to 56 of 56 entries
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The Gut Microbiome as a Target for IBD Treatment: Are We There Yet?.

Current treatment options in gastroenterology

Knox NC, Forbes JD, Van Domselaar G, Bernstein CN.
PMID: 30661163
Curr Treat Options Gastroenterol. 2019 Mar;17(1):115-126. doi: 10.1007/s11938-019-00221-w.

PURPOSE OF REVIEW: This review aims to highlight recent research on the gut microbiome in IBD and the application of microbiome-modulating therapies for the treatment of IBD including the use of the microbiome as an indicator for disease severity...

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Knox NC, Forbes JD, Van Domselaar G, et al. The Gut Microbiome as a Target for IBD Treatment: Are We There Yet?. Curr Treat Options Gastroenterol. 2019;17(1):115-126doi: 10.1007/s11938-019-00221-w.
Knox, N. C., Forbes, J. D., Van Domselaar, G., & Bernstein, C. N. (2019). The Gut Microbiome as a Target for IBD Treatment: Are We There Yet?. Current treatment options in gastroenterology, 17(1), 115-126. https://doi.org/10.1007/s11938-019-00221-w
Knox, Natalie C, et al. "The Gut Microbiome as a Target for IBD Treatment: Are We There Yet?." Current treatment options in gastroenterology vol. 17,1 (2019): 115-126. doi: https://doi.org/10.1007/s11938-019-00221-w
Knox NC, Forbes JD, Van Domselaar G, Bernstein CN. The Gut Microbiome as a Target for IBD Treatment: Are We There Yet?. Curr Treat Options Gastroenterol. 2019 Mar;17(1):115-126. doi: 10.1007/s11938-019-00221-w. PMID: 30661163.
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Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome - a diagnostic in vitro tissue remodeling platform.

Journal of experimental orthopaedics

van Vijven M, van Groningen B, Kimenai JN, van der Steen MC, van Doeselaar M, Janssen RPA, Ito K, Foolen J.
PMID: 32623555
J Exp Orthop. 2020 Jul 04;7(1):48. doi: 10.1186/s40634-020-00266-2.

PURPOSE: Upon anterior cruciate ligament (ACL) rupture, reconstruction is often required, with the hamstring tendon autograft as most widely used treatment. Post-operative autograft remodeling enhances graft rupture risk, which occurs in up to 10% of the patient population, increasing...

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van Vijven M, van Groningen B, Kimenai JN, et al. Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome - a diagnostic in vitro tissue remodeling platform. J Exp Orthop. 2020;7(1):48doi: 10.1186/s40634-020-00266-2.
van Vijven, M., van Groningen, B., Kimenai, J. N., van der Steen, M. C., van Doeselaar, M., Janssen, R. P. A., Ito, K., & Foolen, J. (2020). Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome - a diagnostic in vitro tissue remodeling platform. Journal of experimental orthopaedics, 7(1), 48. https://doi.org/10.1186/s40634-020-00266-2
van Vijven, Marc, et al. "Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome - a diagnostic in vitro tissue remodeling platform." Journal of experimental orthopaedics vol. 7,1 (2020): 48. doi: https://doi.org/10.1186/s40634-020-00266-2
van Vijven M, van Groningen B, Kimenai JN, van der Steen MC, van Doeselaar M, Janssen RPA, Ito K, Foolen J. Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome - a diagnostic in vitro tissue remodeling platform. J Exp Orthop. 2020 Jul 04;7(1):48. doi: 10.1186/s40634-020-00266-2. PMID: 32623555; PMCID: PMC7335379.
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Local variations in mechanical properties of human hamstring tendon autografts for anterior cruciate ligament reconstruction do not translate to a mechanically inferior strand.

Journal of the mechanical behavior of biomedical materials

van Vijven M, van Groningen B, Janssen RPA, van der Steen MC, van Doeselaar M, Stefanoska D, van Donkelaar CC, Ito K, Foolen J.
PMID: 34896765
J Mech Behav Biomed Mater. 2021 Dec 03;126:105010. doi: 10.1016/j.jmbbm.2021.105010. Epub 2021 Dec 03.

A ruptured anterior cruciate ligament (ACL) is often reconstructed with a multiple-strand autograft of a semitendinosus tendon alone or combined with a gracilis tendon. Up to 10% of patients experience graft rupture. This potentially results from excessive local tissue...

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van Vijven M, van Groningen B, Janssen RPA, et al. Local variations in mechanical properties of human hamstring tendon autografts for anterior cruciate ligament reconstruction do not translate to a mechanically inferior strand. J Mech Behav Biomed Mater. 2021;126:105010doi: 10.1016/j.jmbbm.2021.105010.
van Vijven, M., van Groningen, B., Janssen, R. P. A., van der Steen, M. C., van Doeselaar, M., Stefanoska, D., van Donkelaar, C. C., Ito, K., & Foolen, J. (2021). Local variations in mechanical properties of human hamstring tendon autografts for anterior cruciate ligament reconstruction do not translate to a mechanically inferior strand. Journal of the mechanical behavior of biomedical materials, 126105010. https://doi.org/10.1016/j.jmbbm.2021.105010
van Vijven, M, et al. "Local variations in mechanical properties of human hamstring tendon autografts for anterior cruciate ligament reconstruction do not translate to a mechanically inferior strand." Journal of the mechanical behavior of biomedical materials vol. 126 (2021): 105010. doi: https://doi.org/10.1016/j.jmbbm.2021.105010
van Vijven M, van Groningen B, Janssen RPA, van der Steen MC, van Doeselaar M, Stefanoska D, van Donkelaar CC, Ito K, Foolen J. Local variations in mechanical properties of human hamstring tendon autografts for anterior cruciate ligament reconstruction do not translate to a mechanically inferior strand. J Mech Behav Biomed Mater. 2021 Dec 03;126:105010. doi: 10.1016/j.jmbbm.2021.105010. Epub 2021 Dec 03. PMID: 34896765.
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Rapid and accurate SNP genotyping of clonal bacterial pathogens with BioHansel.

Microbial genomics

Labbé G, Kruczkiewicz P, Robertson J, Mabon P, Schonfeld J, Kein D, Rankin MA, Gopez M, Hole D, Son D, Knox N, Laing CR, Bessonov K, Taboada EN, Yoshida C, Ziebell K, Nichani A, Johnson RP, Van Domselaar G, Nash JHE.
PMID: 34554082
Microb Genom. 2021 Sep;7(9). doi: 10.1099/mgen.0.000651.

Hierarchical genotyping approaches can provide insights into the source, geography and temporal distribution of bacterial pathogens. Multiple hierarchical SNP genotyping schemes have previously been developed so that new isolates can rapidly be placed within pre-computed population structures, without the...

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Labbé G, Kruczkiewicz P, Robertson J, et al. Rapid and accurate SNP genotyping of clonal bacterial pathogens with BioHansel. Microb Genom. 2021;7(9)doi: 10.1099/mgen.0.000651.
Labbé, G., Kruczkiewicz, P., Robertson, J., Mabon, P., Schonfeld, J., Kein, D., Rankin, M. A., Gopez, M., Hole, D., Son, D., Knox, N., Laing, C. R., Bessonov, K., Taboada, E. N., Yoshida, C., Ziebell, K., Nichani, A., Johnson, R. P., Van Domselaar, G., & Nash, J. H. E. (2021). Rapid and accurate SNP genotyping of clonal bacterial pathogens with BioHansel. Microbial genomics, 7(9), . https://doi.org/10.1099/mgen.0.000651
Labbé, Geneviève, et al. "Rapid and accurate SNP genotyping of clonal bacterial pathogens with BioHansel." Microbial genomics vol. 7,9 (2021). doi: https://doi.org/10.1099/mgen.0.000651
Labbé G, Kruczkiewicz P, Robertson J, Mabon P, Schonfeld J, Kein D, Rankin MA, Gopez M, Hole D, Son D, Knox N, Laing CR, Bessonov K, Taboada EN, Yoshida C, Ziebell K, Nichani A, Johnson RP, Van Domselaar G, Nash JHE. Rapid and accurate SNP genotyping of clonal bacterial pathogens with BioHansel. Microb Genom. 2021 Sep;7(9). doi: 10.1099/mgen.0.000651. PMID: 34554082; PMCID: PMC8715432.
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High accuracy, fiducial marker-based image registration of correlative microscopy images.

Scientific reports

Mohammadian S, Fokkema J, Agronskaia AV, Liv N, de Heus C, van Donselaar E, Blab GA, Klumperman J, Gerritsen HC.
PMID: 30824844
Sci Rep. 2019 Mar 01;9(1):3211. doi: 10.1038/s41598-019-40098-4.

Fluorescence microscopy (FM) and electron microscopy (EM) are complementary techniques. FM affords examination of large fields of view and identifying regions of interest but has a low resolution. EM exhibits excellent resolution over a limited field of view. The...

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Mohammadian S, Fokkema J, Agronskaia AV, et al. High accuracy, fiducial marker-based image registration of correlative microscopy images. Sci Rep. 2019;9(1):3211doi: 10.1038/s41598-019-40098-4.
Mohammadian, S., Fokkema, J., Agronskaia, A. V., Liv, N., de Heus, C., van Donselaar, E., Blab, G. A., Klumperman, J., & Gerritsen, H. C. (2019). High accuracy, fiducial marker-based image registration of correlative microscopy images. Scientific reports, 9(1), 3211. https://doi.org/10.1038/s41598-019-40098-4
Mohammadian, Sajjad, et al. "High accuracy, fiducial marker-based image registration of correlative microscopy images." Scientific reports vol. 9,1 (2019): 3211. doi: https://doi.org/10.1038/s41598-019-40098-4
Mohammadian S, Fokkema J, Agronskaia AV, Liv N, de Heus C, van Donselaar E, Blab GA, Klumperman J, Gerritsen HC. High accuracy, fiducial marker-based image registration of correlative microscopy images. Sci Rep. 2019 Mar 01;9(1):3211. doi: 10.1038/s41598-019-40098-4. PMID: 30824844; PMCID: PMC6397213.
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Single Immunization of a Vaccine Vectored by a Novel Recombinant Vaccinia Virus Affords Effective Protection Against Respiratory Syncytial Virus Infection in Cotton Rats.

Frontiers in immunology

Russell MS, Thulasi Raman SN, Gravel C, Zhang W, Pfeifle A, Chen W, Van Domselaar G, Safronetz D, Johnston M, Sauve S, Wang L, Rosu-Myles M, Cao J, Li X.
PMID: 34603336
Front Immunol. 2021 Sep 17;12:747866. doi: 10.3389/fimmu.2021.747866. eCollection 2021.

Respiratory syncytial virus (RSV) is a leading cause of respiratory infections worldwide and disease management measures are hampered by the lack of a safe and effective vaccine against the infection. We constructed a novel recombinant RSV vaccine candidate based...

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Russell MS, Thulasi Raman SN, Gravel C, et al. Single Immunization of a Vaccine Vectored by a Novel Recombinant Vaccinia Virus Affords Effective Protection Against Respiratory Syncytial Virus Infection in Cotton Rats. Front Immunol. 2021;12:747866doi: 10.3389/fimmu.2021.747866.
Russell, M. S., Thulasi Raman, S. N., Gravel, C., Zhang, W., Pfeifle, A., Chen, W., Van Domselaar, G., Safronetz, D., Johnston, M., Sauve, S., Wang, L., Rosu-Myles, M., Cao, J., & Li, X. (2021). Single Immunization of a Vaccine Vectored by a Novel Recombinant Vaccinia Virus Affords Effective Protection Against Respiratory Syncytial Virus Infection in Cotton Rats. Frontiers in immunology, 12747866. https://doi.org/10.3389/fimmu.2021.747866
Russell, Marsha S, et al. "Single Immunization of a Vaccine Vectored by a Novel Recombinant Vaccinia Virus Affords Effective Protection Against Respiratory Syncytial Virus Infection in Cotton Rats." Frontiers in immunology vol. 12 (2021): 747866. doi: https://doi.org/10.3389/fimmu.2021.747866
Russell MS, Thulasi Raman SN, Gravel C, Zhang W, Pfeifle A, Chen W, Van Domselaar G, Safronetz D, Johnston M, Sauve S, Wang L, Rosu-Myles M, Cao J, Li X. Single Immunization of a Vaccine Vectored by a Novel Recombinant Vaccinia Virus Affords Effective Protection Against Respiratory Syncytial Virus Infection in Cotton Rats. Front Immunol. 2021 Sep 17;12:747866. doi: 10.3389/fimmu.2021.747866. eCollection 2021. PMID: 34603336; PMCID: PMC8484905.
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The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes.

Annals of clinical and translational neurology

Tremlett H, Zhu F, Arnold D, Bar-Or A, Bernstein CN, Bonner C, Forbes JD, Graham M, Hart J, Knox NC, Marrie RA, Mirza AI, O'Mahony J, Van Domselaar G, Yeh EA, Zhao Y, Banwell B, Waubant E.
PMID: 34889081
Ann Clin Transl Neurol. 2021 Dec;8(12):2252-2269. doi: 10.1002/acn3.51476. Epub 2021 Dec 09.

OBJECTIVE: To examine the gut microbiota in individuals with and without pediatric-onset multiple sclerosis (MS).METHODS: We compared stool-derived microbiota of Canadian Pediatric Demyelinating Disease Network study participants ≤21 years old, with MS (disease-modifying drug [DMD] exposed and naïve) or...

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Tremlett H, Zhu F, Arnold D, et al. The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes. Ann Clin Transl Neurol. 2021;8(12):2252-2269doi: 10.1002/acn3.51476.
Tremlett, H., Zhu, F., Arnold, D., Bar-Or, A., Bernstein, C. N., Bonner, C., Forbes, J. D., Graham, M., Hart, J., Knox, N. C., Marrie, R. A., Mirza, A. I., O'Mahony, J., Van Domselaar, G., Yeh, E. A., Zhao, Y., Banwell, B., Waubant, E. (2021). The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes. Annals of clinical and translational neurology, 8(12), 2252-2269. https://doi.org/10.1002/acn3.51476
Tremlett, Helen, et al. "The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes." Annals of clinical and translational neurology vol. 8,12 (2021): 2252-2269. doi: https://doi.org/10.1002/acn3.51476
Tremlett H, Zhu F, Arnold D, Bar-Or A, Bernstein CN, Bonner C, Forbes JD, Graham M, Hart J, Knox NC, Marrie RA, Mirza AI, O'Mahony J, Van Domselaar G, Yeh EA, Zhao Y, Banwell B, Waubant E. The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes. Ann Clin Transl Neurol. 2021 Dec;8(12):2252-2269. doi: 10.1002/acn3.51476. Epub 2021 Dec 09. PMID: 34889081; PMCID: PMC8670321.
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A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function.

Molecular metabolism

Kroon J, Schilperoort M, In Het Panhuis W, van den Berg R, van Doeselaar L, Verzijl CRC, van Trigt N, Mol IM, Sips HHCM, van den Heuvel JK, Koorneef LL, van der Sluis RJ, Fenzl A, Kiefer FW, Vettorazzi S, Tuckermann JP, Biermasz NR, Meijer OC, Rensen PCN, Kooijman S.
PMID: 33548499
Mol Metab. 2021 May;47:101179. doi: 10.1016/j.molmet.2021.101179. Epub 2021 Feb 03.

OBJECTIVE: Brown adipose tissue (BAT) displays a strong circadian rhythm in metabolic activity, but it is unclear how this rhythm is regulated. As circulating levels of corticosterone coincide with the rhythm of triglyceride-derived fatty acid (FA) uptake by BAT,...

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Kroon J, Schilperoort M, In Het Panhuis W, et al. A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function. Mol Metab. 2021;47:101179doi: 10.1016/j.molmet.2021.101179.
Kroon, J., Schilperoort, M., In Het Panhuis, W., van den Berg, R., van Doeselaar, L., Verzijl, C. R. C., van Trigt, N., Mol, I. M., Sips, H. H. C. M., van den Heuvel, J. K., Koorneef, L. L., van der Sluis, R. J., Fenzl, A., Kiefer, F. W., Vettorazzi, S., Tuckermann, J. P., Biermasz, N. R., Meijer, O. C., Rensen, P. C. N., & Kooijman, S. (2021). A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function. Molecular metabolism, 47101179. https://doi.org/10.1016/j.molmet.2021.101179
Kroon, Jan, et al. "A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function." Molecular metabolism vol. 47 (2021): 101179. doi: https://doi.org/10.1016/j.molmet.2021.101179
Kroon J, Schilperoort M, In Het Panhuis W, van den Berg R, van Doeselaar L, Verzijl CRC, van Trigt N, Mol IM, Sips HHCM, van den Heuvel JK, Koorneef LL, van der Sluis RJ, Fenzl A, Kiefer FW, Vettorazzi S, Tuckermann JP, Biermasz NR, Meijer OC, Rensen PCN, Kooijman S. A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function. Mol Metab. 2021 May;47:101179. doi: 10.1016/j.molmet.2021.101179. Epub 2021 Feb 03. PMID: 33548499; PMCID: PMC7907824.
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Showing 49 to 56 of 56 entries