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Showing 385 to 392 of 392 entries
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Electric field control of chirality.

Science advances

Behera P, May MA, Gómez-Ortiz F, Susarla S, Das S, Nelson CT, Caretta L, Hsu SL, McCarter MR, Savitzky BH, Barnard ES, Raja A, Hong Z, García-Fernandez P, Lovesey SW, van der Laan G, Ercius P, Ophus C, Martin LW, Junquera J, Raschke MB, Ramesh R.
PMID: 34985953
Sci Adv. 2022 Jan 07;8(1):eabj8030. doi: 10.1126/sciadv.abj8030. Epub 2022 Jan 05.

[Figure: see text].

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Behera P, May MA, Gómez-Ortiz F, et al. Electric field control of chirality. Sci Adv. 2022;8(1):eabj8030doi: 10.1126/sciadv.abj8030.
Behera, P., May, M. A., Gómez-Ortiz, F., Susarla, S., Das, S., Nelson, C. T., Caretta, L., Hsu, S. L., McCarter, M. R., Savitzky, B. H., Barnard, E. S., Raja, A., Hong, Z., García-Fernandez, P., Lovesey, S. W., van der Laan, G., Ercius, P., Ophus, C., Martin, L. W., Junquera, J., Raschke, M. B., & Ramesh, R. (2022). Electric field control of chirality. Science advances, 8(1), eabj8030. https://doi.org/10.1126/sciadv.abj8030
Behera, Piush, et al. "Electric field control of chirality." Science advances vol. 8,1 (2022): eabj8030. doi: https://doi.org/10.1126/sciadv.abj8030
Behera P, May MA, Gómez-Ortiz F, Susarla S, Das S, Nelson CT, Caretta L, Hsu SL, McCarter MR, Savitzky BH, Barnard ES, Raja A, Hong Z, García-Fernandez P, Lovesey SW, van der Laan G, Ercius P, Ophus C, Martin LW, Junquera J, Raschke MB, Ramesh R. Electric field control of chirality. Sci Adv. 2022 Jan 07;8(1):eabj8030. doi: 10.1126/sciadv.abj8030. Epub 2022 Jan 05. PMID: 34985953.
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Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial.

medRxiv : the preprint server for health sciences

Gilbert PB, Montefiori DC, McDermott A, Fong Y, Benkeser D, Deng W, Zhou H, Houchens CR, Martins K, Jayashankar L, Castellino F, Flach B, Lin BC, O'Connell S, McDanal C, Eaton A, Sarzotti-Kelsoe M, Lu Y, Yu C, Borate B, van der Laan LWP, Hejazi N, Huynh C, Miller J, El Sahly HM, Baden LR, Baron M, De La Cruz L, Gay C, Kalams S, Kelley CF, Kutner M, Andrasik MP, Kublin JG, Corey L, Neuzil KM, Carpp LN, Pajon R, Follmann D, Donis RO, Koup RA.
PMID: 34401888
medRxiv. 2021 Aug 15; doi: 10.1101/2021.08.09.21261290.

BACKGROUND: In the Coronavirus Efficacy (COVE) trial, estimated mRNA-1273 vaccine efficacy against coronavirus disease-19 (COVID-19) was 94%. SARS-CoV-2 antibody measurements were assessed as correlates of COVID-19 risk and as correlates of protection.METHODS: Through case-cohort sampling, participants were selected for...

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Gilbert PB, Montefiori DC, McDermott A, et al. Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial. medRxiv. 2021;doi: 10.1101/2021.08.09.21261290.
Gilbert, P. B., Montefiori, D. C., McDermott, A., Fong, Y., Benkeser, D., Deng, W., Zhou, H., Houchens, C. R., Martins, K., Jayashankar, L., Castellino, F., Flach, B., Lin, B. C., O'Connell, S., McDanal, C., Eaton, A., Sarzotti-Kelsoe, M., Lu, Y., Yu, C., Borate, B., van der Laan, L. W. P., Hejazi, N., Huynh, C., Miller, J., El Sahly, H. M., Baden, L. R., Baron, M., De La Cruz, L., Gay, C., Kalams, S., Kelley, C. F., Kutner, M., Andrasik, M. P., Kublin, J. G., Corey, L., Neuzil, K. M., Carpp, L. N., Pajon, R., Follmann, D., Donis, R. O., & Koup, R. A. (2021). Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial. medRxiv : the preprint server for health sciences, . https://doi.org/10.1101/2021.08.09.21261290
Gilbert, Peter B, et al. "Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial." medRxiv : the preprint server for health sciences vol. (2021). doi: https://doi.org/10.1101/2021.08.09.21261290
Gilbert PB, Montefiori DC, McDermott A, Fong Y, Benkeser D, Deng W, Zhou H, Houchens CR, Martins K, Jayashankar L, Castellino F, Flach B, Lin BC, O'Connell S, McDanal C, Eaton A, Sarzotti-Kelsoe M, Lu Y, Yu C, Borate B, van der Laan LWP, Hejazi N, Huynh C, Miller J, El Sahly HM, Baden LR, Baron M, De La Cruz L, Gay C, Kalams S, Kelley CF, Kutner M, Andrasik MP, Kublin JG, Corey L, Neuzil KM, Carpp LN, Pajon R, Follmann D, Donis RO, Koup RA. Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial. medRxiv. 2021 Aug 15; doi: 10.1101/2021.08.09.21261290. PMID: 34401888; PMCID: PMC8366808.
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Two-Stage TMLE to reduce bias and improve efficiency in cluster randomized trials.

Biostatistics (Oxford, England)

Balzer LB, van der Laan M, Ayieko J, Kamya M, Chamie G, Schwab J, Havlir DV, Petersen ML.
PMID: 34939083
Biostatistics. 2021 Dec 23; doi: 10.1093/biostatistics/kxab043. Epub 2021 Dec 23.

Cluster randomized trials (CRTs) randomly assign an intervention to groups of individuals (e.g., clinics or communities) and measure outcomes on individuals in those groups. While offering many advantages, this experimental design introduces challenges that are only partially addressed by...

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Balzer LB, van der Laan M, Ayieko J, et al. Two-Stage TMLE to reduce bias and improve efficiency in cluster randomized trials. Biostatistics. 2021;doi: 10.1093/biostatistics/kxab043.
Balzer, L. B., van der Laan, M., Ayieko, J., Kamya, M., Chamie, G., Schwab, J., Havlir, D. V., & Petersen, M. L. (2021). Two-Stage TMLE to reduce bias and improve efficiency in cluster randomized trials. Biostatistics (Oxford, England), . https://doi.org/10.1093/biostatistics/kxab043
Balzer, Laura B, et al. "Two-Stage TMLE to reduce bias and improve efficiency in cluster randomized trials." Biostatistics (Oxford, England) vol. (2021). doi: https://doi.org/10.1093/biostatistics/kxab043
Balzer LB, van der Laan M, Ayieko J, Kamya M, Chamie G, Schwab J, Havlir DV, Petersen ML. Two-Stage TMLE to reduce bias and improve efficiency in cluster randomized trials. Biostatistics. 2021 Dec 23; doi: 10.1093/biostatistics/kxab043. Epub 2021 Dec 23. PMID: 34939083.
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Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids.

BMC biotechnology

Roest HP, IJzermans JNM, van der Laan LJW.
PMID: 34362351
BMC Biotechnol. 2021 Aug 06;21(1):48. doi: 10.1186/s12896-021-00706-6.

BACKGROUND: Extracellular microRNAs (miRNAs), released from cells into biofluids, have emerged as promising biomarkers for diagnostic and prognostic purposes. Several RNA isolation methods are available for the analysis of these cell-free miRNAs by RT-qPCR. Not all methods, however, are...

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Roest HP, IJzermans JNM, van der Laan LJW. Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids. BMC Biotechnol. 2021;21(1):48doi: 10.1186/s12896-021-00706-6.
Roest, H. P., IJzermans, J. N. M., & van der Laan, L. J. W. (2021). Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids. BMC biotechnology, 21(1), 48. https://doi.org/10.1186/s12896-021-00706-6
Roest, Henk P, et al. "Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids." BMC biotechnology vol. 21,1 (2021): 48. doi: https://doi.org/10.1186/s12896-021-00706-6
Roest HP, IJzermans JNM, van der Laan LJW. Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids. BMC Biotechnol. 2021 Aug 06;21(1):48. doi: 10.1186/s12896-021-00706-6. PMID: 34362351; PMCID: PMC8344161.
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Maternal adverse childhood experiences before pregnancy are associated with epigenetic aging changes in their children.

Aging

Nwanaji-Enwerem JC, Van Der Laan L, Kogut K, Eskenazi B, Holland N, Deardorff J, Cardenas A.
PMID: 34923483
Aging (Albany NY). 2021 Dec 18;13(24):25653-25669. doi: 10.18632/aging.203776. Epub 2021 Dec 18.

Emerging research suggests associations of physical and psychosocial stressors with epigenetic aging. Although this work has included early-life exposures, data on maternal exposures and epigenetic aging of their children remain sparse. Using longitudinally collected data from the California, Salinas...

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Nwanaji-Enwerem JC, Van Der Laan L, Kogut K, et al. Maternal adverse childhood experiences before pregnancy are associated with epigenetic aging changes in their children. Aging (Albany NY). 2021;13(24):25653-25669doi: 10.18632/aging.203776.
Nwanaji-Enwerem, J. C., Van Der Laan, L., Kogut, K., Eskenazi, B., Holland, N., Deardorff, J., & Cardenas, A. (2021). Maternal adverse childhood experiences before pregnancy are associated with epigenetic aging changes in their children. Aging, 13(24), 25653-25669. https://doi.org/10.18632/aging.203776
Nwanaji-Enwerem, Jamaji C, et al. "Maternal adverse childhood experiences before pregnancy are associated with epigenetic aging changes in their children." Aging vol. 13,24 (2021): 25653-25669. doi: https://doi.org/10.18632/aging.203776
Nwanaji-Enwerem JC, Van Der Laan L, Kogut K, Eskenazi B, Holland N, Deardorff J, Cardenas A. Maternal adverse childhood experiences before pregnancy are associated with epigenetic aging changes in their children. Aging (Albany NY). 2021 Dec 18;13(24):25653-25669. doi: 10.18632/aging.203776. Epub 2021 Dec 18. PMID: 34923483.
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An epigenetic aging analysis of randomized metformin and weight loss interventions in overweight postmenopausal breast cancer survivors.

Clinical epigenetics

Nwanaji-Enwerem JC, Chung FF, Van der Laan L, Novoloaca A, Cuenin C, Johansson H, Bonanni B, Hubbard AE, Smith MT, Hartman SJ, Cardenas A, Sears DD, Herceg Z.
PMID: 34920739
Clin Epigenetics. 2021 Dec 17;13(1):224. doi: 10.1186/s13148-021-01218-y.

Metformin and weight loss relationships with epigenetic age measures-biological aging biomarkers-remain understudied. We performed a post-hoc analysis of a randomized controlled trial among overweight/obese breast cancer survivors (N = 192) assigned to metformin, placebo, weight loss with metformin, or...

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Nwanaji-Enwerem JC, Chung FF, Van der Laan L, et al. An epigenetic aging analysis of randomized metformin and weight loss interventions in overweight postmenopausal breast cancer survivors. Clin Epigenetics. 2021;13(1):224doi: 10.1186/s13148-021-01218-y.
Nwanaji-Enwerem, J. C., Chung, F. F., Van der Laan, L., Novoloaca, A., Cuenin, C., Johansson, H., Bonanni, B., Hubbard, A. E., Smith, M. T., Hartman, S. J., Cardenas, A., Sears, D. D., & Herceg, Z. (2021). An epigenetic aging analysis of randomized metformin and weight loss interventions in overweight postmenopausal breast cancer survivors. Clinical epigenetics, 13(1), 224. https://doi.org/10.1186/s13148-021-01218-y
Nwanaji-Enwerem, Jamaji C, et al. "An epigenetic aging analysis of randomized metformin and weight loss interventions in overweight postmenopausal breast cancer survivors." Clinical epigenetics vol. 13,1 (2021): 224. doi: https://doi.org/10.1186/s13148-021-01218-y
Nwanaji-Enwerem JC, Chung FF, Van der Laan L, Novoloaca A, Cuenin C, Johansson H, Bonanni B, Hubbard AE, Smith MT, Hartman SJ, Cardenas A, Sears DD, Herceg Z. An epigenetic aging analysis of randomized metformin and weight loss interventions in overweight postmenopausal breast cancer survivors. Clin Epigenetics. 2021 Dec 17;13(1):224. doi: 10.1186/s13148-021-01218-y. PMID: 34920739.
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Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids.

Cellular and molecular gastroenterology and hepatology

Shi S, Verstegen MMA, Roest HP, Ardisasmita AI, Cao W, Roos FJM, de Ruiter PE, Niemeijer M, Pan Q, IJzermans JNM, van der Laan LJW.
PMID: 34700031
Cell Mol Gastroenterol Hepatol. 2021 Oct 23;13(2):541-564. doi: 10.1016/j.jcmgh.2021.10.009. Epub 2021 Oct 23.

BACKGROUND & AIMS: Liver and bile duct diseases often are associated with extensive cell death of cholangiocytes. Necroptosis represents a common mode of programmed cell death in cholangiopathy, however, detailed mechanistic knowledge is limited owing to the lack of...

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Shi S, Verstegen MMA, Roest HP, et al. Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids. Cell Mol Gastroenterol Hepatol. 2021;13(2):541-564doi: 10.1016/j.jcmgh.2021.10.009.
Shi, S., Verstegen, M. M. A., Roest, H. P., Ardisasmita, A. I., Cao, W., Roos, F. J. M., de Ruiter, P. E., Niemeijer, M., Pan, Q., IJzermans, J. N. M., & van der Laan, L. J. W. (2021). Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids. Cellular and molecular gastroenterology and hepatology, 13(2), 541-564. https://doi.org/10.1016/j.jcmgh.2021.10.009
Shi, Shaojun, et al. "Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids." Cellular and molecular gastroenterology and hepatology vol. 13,2 (2021): 541-564. doi: https://doi.org/10.1016/j.jcmgh.2021.10.009
Shi S, Verstegen MMA, Roest HP, Ardisasmita AI, Cao W, Roos FJM, de Ruiter PE, Niemeijer M, Pan Q, IJzermans JNM, van der Laan LJW. Recapitulating Cholangiopathy-Associated Necroptotic Cell Death In Vitro Using Human Cholangiocyte Organoids. Cell Mol Gastroenterol Hepatol. 2021 Oct 23;13(2):541-564. doi: 10.1016/j.jcmgh.2021.10.009. Epub 2021 Oct 23. PMID: 34700031.
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Treatment of patch infection after carotid endarterectomy: a systematic review.

Annals of translational medicine

Wikkeling TM, van Gijssel SA, van der Laan MJ, Zeebregts CJ, Saleem BR.
PMID: 34430654
Ann Transl Med. 2021 Jul;9(14):1213. doi: 10.21037/atm-20-7531.

Carotid endarterectomy (CEA) with patch angioplasty is a widely used method for treating carotid artery stenosis. Patch infections are extremely rare, but the consequences may be serious. The current gold standard for treatment is patch excision and reconstruction with...

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Wikkeling TM, van Gijssel SA, van der Laan MJ, et al. Treatment of patch infection after carotid endarterectomy: a systematic review. Ann Transl Med. 2021;9(14):1213doi: 10.21037/atm-20-7531.
Wikkeling, T. M., van Gijssel, S. A., van der Laan, M. J., Zeebregts, C. J., & Saleem, B. R. (2021). Treatment of patch infection after carotid endarterectomy: a systematic review. Annals of translational medicine, 9(14), 1213. https://doi.org/10.21037/atm-20-7531
Wikkeling, Tim M, et al. "Treatment of patch infection after carotid endarterectomy: a systematic review." Annals of translational medicine vol. 9,14 (2021): 1213. doi: https://doi.org/10.21037/atm-20-7531
Wikkeling TM, van Gijssel SA, van der Laan MJ, Zeebregts CJ, Saleem BR. Treatment of patch infection after carotid endarterectomy: a systematic review. Ann Transl Med. 2021 Jul;9(14):1213. doi: 10.21037/atm-20-7531. PMID: 34430654; PMCID: PMC8350672.
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Showing 385 to 392 of 392 entries