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Showing 25 to 36 of 106 entries
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Magnetic sequencing.

Nature methods

Linnarsson S.
PMID: 22453909
Nat Methods. 2012 Mar 27;9(4):339, 341. doi: 10.1038/nmeth.1934.

No abstract available.

Pathway and network analysis with high-density allelic association data.

Methods in molecular biology (Clifton, N.J.)

Torkamani A, Schork NJ.
PMID: 19597792
Methods Mol Biol. 2009;563:289-301. doi: 10.1007/978-1-60761-175-2_16.

Network and pathway analysis tools are traditionally used to interrogate gene expression data in order to understand the biological processes affected by a particular manipulation or disease/condition of interest. A systems-level understanding of the biological processes affected in particular...

Design of large-insert jumping libraries for structural variant detection using Illumina sequencing.

Current protocols in human genetics

Hanscom C, Talkowski M.
PMID: 24789519
Curr Protoc Hum Genet. 2014 Jan 23;80:7.22.1-9. doi: 10.1002/0471142905.hg0722s80.

Next-generation sequencing is an important and efficient tool for the identification of structural variation, particularly balanced chromosomal rearrangements, because such events are not routinely detected by microarray and localization of altered regions by karyotype is imprecise. Indeed, the degree...

Hierarchical modeling for synthetic biology.

ACS synthetic biology

Chandran D, Sauro HM.
PMID: 23651289
ACS Synth Biol. 2012 Aug 17;1(8):353-64. doi: 10.1021/sb300033q. Epub 2012 Aug 10.

One of the characteristics of synthetic biology is that it often combines mathematical modeling with experimental work. The link between modeling and experiments is carried out by human researchers who have a conceptual understanding of the underlying biological system....

The science, applications, and ethical concerns surrounding low copy number DNA analysis.

Genetic testing and molecular biomarkers

Schulz R, Terry SF.
PMID: 26053787
Genet Test Mol Biomarkers. 2015 Jun;19(6):281-2. doi: 10.1089/gtmb.2015.29000.rjs.

No abstract available.

A response to a response to Meakin and Jamieson DNA transfer: Review and implications for casework.

Forensic science international. Genetics

Meakin GE, Jamieson A.
PMID: 26925760
Forensic Sci Int Genet. 2016 May;22:e5-e6. doi: 10.1016/j.fsigen.2016.02.010. Epub 2016 Feb 22.

No abstract available.

Environmental versus extra-organismal DNA.

Molecular ecology

Pawlowski J, Apothéloz-Perret-Gentil L, Altermatt F.
PMID: 34498334
Mol Ecol. 2021 Oct;30(19):4606-4607. doi: 10.1111/mec.16144. Epub 2021 Sep 09.

No abstract available.

Pac-Man like DNA cut-and-paste tool allows larger gene edits.

Communications biology

Akhtar A.
PMID: 33219320
Commun Biol. 2020 Nov 20;3(1):709. doi: 10.1038/s42003-020-01446-7.

No abstract available.

DNA barcodes using a double nanopore system.

Scientific reports

Seth S, Bhattacharya A.
PMID: 33963199
Sci Rep. 2021 May 07;11(1):9799. doi: 10.1038/s41598-021-89017-6.

The potential of a double nanopore system to determine DNA barcodes has been demonstrated experimentally. By carrying out Brownian dynamics simulation on a coarse-grained model DNA with protein tag (barcodes) at known locations along the chain backbone, we demonstrate...

ASTE1 cutting to block DNA end resection.

Nature cell biology

He YJ, Chowdhury D.
PMID: 34354234
Nat Cell Biol. 2021 Aug;23(8):818-819. doi: 10.1038/s41556-021-00731-9.

No abstract available.

Model and modelers provide an insight into pairing of homologous DNA duplexes.

Proceedings of the National Academy of Sciences of the United States of America

Catcheside DEA.
PMID: 34544880
Proc Natl Acad Sci U S A. 2021 Sep 28;118(39). doi: 10.1073/pnas.2114127118.

No abstract available.

The role of extracellular DNA (exDNA) in cellular processes.

Cancer biology & therapy

Fernández-Domínguez IJ, Manzo-Merino J, Taja-Chayeb L, Dueñas-González A, Pérez-Cárdenas E, Trejo-Becerril C.
PMID: 33858306
Cancer Biol Ther. 2021 Apr 03;22(4):267-278. doi: 10.1080/15384047.2021.1890319. Epub 2021 Apr 16.

Nowadays, extracellular DNA or circulating cell-free DNA is considered to be a molecule with clinical applications (diagnosis, prognosis, monitoring of treatment responses, or patient follow-up) in diverse pathologies, especially in cancer. Nevertheless, because of its molecular characteristics, it can...

Showing 25 to 36 of 106 entries