Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 73 to 83 of 83 entries
Sorted by: Best Match Show Resources per page
Quantitative assessment of TLR4 gene polymorphisms and T2DM risk: A meta-analysis.

Molecular genetics & genomic medicine

Fan J, Liang R.
PMID: 32822111
Mol Genet Genomic Med. 2020 Oct;8(10):e1466. doi: 10.1002/mgg3.1466. Epub 2020 Aug 21.

BACKGROUND: Numerous studies have evaluated the association between TLR4 gene polymorphisms and T2DM risk. However, the findings were inconsistent and controversial.METHODS: In order to drive a more precise estimation, we carried out a meta-analysis based on 41 studies involving...

Human Genetics of Obesity and Type 2 Diabetes Mellitus: Past, Present, and Future.

Circulation. Genomic and precision medicine

Ingelsson E, McCarthy MI.
PMID: 29899044
Circ Genom Precis Med. 2018 Jun;11(6):e002090. doi: 10.1161/CIRCGEN.118.002090.

Type 2 diabetes mellitus (T2D) and obesity already represent 2 of the most prominent risk factors for cardiovascular disease, and are destined to increase in importance given the global changes in lifestyle. Ten years have passed since the first...

Gene Expression Mining in Type 2 Diabetes Research.

Methods in molecular biology (Clifton, N.J.)

Dunbar DR.
PMID: 31586324
Methods Mol Biol. 2020;2076:109-117. doi: 10.1007/978-1-4939-9882-1_6.

Gene expression analysis by microarray and more recently by next-generation sequencing has become a core part of biomedical research and its value can be seen in thousands of research papers. A successful gene expression experiment needs to be augmented...

[Why is there a type-2 diabetes?].

Deutsche medizinische Wochenschrift (1946)

Ritz E.
PMID: 8482235
Dtsch Med Wochenschr. 1993 Apr 23;118(16):602-3. doi: 10.1055/s-2008-1059368.

No abstract available.

Prioritizing Type 2 Diabetes Genes by Weighted PageRank on Bilayer Heterogeneous Networks.

IEEE/ACM transactions on computational biology and bioinformatics

Shang H, Liu ZP.
PMID: 31095494
IEEE/ACM Trans Comput Biol Bioinform. 2021 Jan-Feb;18(1):336-346. doi: 10.1109/TCBB.2019.2917190. Epub 2021 Feb 03.

The prevalence of diabetes mellitus has been increasing rapidly in recent years. Type 2 diabetes makes up about 90 percent cases of diabetes. The interacting mixed effects of genetics and environments build possible interpretable pathogenesis. Thus, finding the causal...

Diabetes in China: Epidemiology and Genetic Risk Factors and Their Clinical Utility in Personalized Medication.

Diabetes

Hu C, Jia W.
PMID: 29263166
Diabetes. 2018 Jan;67(1):3-11. doi: 10.2337/dbi17-0013.

The incidence of type 2 diabetes (T2D) has rapidly increased over recent decades, and T2D has become a leading public health challenge in China. Compared with European descents, Chinese patients with T2D are diagnosed at a relatively young age...

Systematically analyses of the common dysregulated networks to understand the common pathologies between T2D and atherosclerosis.

Gene

Lin Z, Yang F, Sun L, Gao J, Cao Y, Qiu H, Zhan X.
PMID: 29705125
Gene. 2018 Sep 10;671:110-116. doi: 10.1016/j.gene.2018.04.078. Epub 2018 Apr 26.

BACKGROUND: Diabetic macroangiopathy, atherosclerosis secondary to diabetes mellitus, causes cerebro-cardiovascular diseases (CVD), which increase the risk of death in patients with DM and significantly reduce their quality of life. Therefore, mechanisms underlying the common shared pathologies between type 2...

Cross-population analysis for functional characterization of type II diabetes variants.

BMC bioinformatics

Elmansy D, Koyutürk M.
PMID: 31216985
BMC Bioinformatics. 2019 Jun 20;20:320. doi: 10.1186/s12859-019-2835-0.

BACKGROUND: As Genome-Wide Association Studies (GWAS) have been increasingly used with data from various populations, it has been observed that data from different populations reveal different sets of Single Nucleotide Polymorphisms (SNPs) that are associated with the same disease....

Identifying molecular insight of synergistic complexities for SARS-CoV-2 infection with pre-existing type 2 diabetes.

Computers in biology and medicine

Islam MB, Chowdhury UN, Nain Z, Uddin S, Ahmed MB, Moni MA.
PMID: 34340124
Comput Biol Med. 2021 Sep;136:104668. doi: 10.1016/j.compbiomed.2021.104668. Epub 2021 Jul 23.

The ongoing COVID-19 outbreak, caused by SARS-CoV-2, has posed a massive threat to global public health, especially to people with underlying health conditions. Type 2 diabetes (T2D) is lethal comorbidity of COVID-19. However, its pathogenetic link remains unclear. This...

Identifying molecular insight of synergistic complexities for SARS-CoV-2 infection with pre-existing type 2 diabetes.

Computers in biology and medicine

Islam MB, Chowdhury UN, Nain Z, Uddin S, Ahmed MB, Moni MA.
PMID: 34340124
Comput Biol Med. 2021 Sep;136:104668. doi: 10.1016/j.compbiomed.2021.104668. Epub 2021 Jul 23.

The ongoing COVID-19 outbreak, caused by SARS-CoV-2, has posed a massive threat to global public health, especially to people with underlying health conditions. Type 2 diabetes (T2D) is lethal comorbidity of COVID-19. However, its pathogenetic link remains unclear. This...

Progress in Defining the Genetic Contribution to Type 2 Diabetes in Individuals of East Asian Ancestry.

Current diabetes reports

Spracklen CN, Sim X.
PMID: 33846905
Curr Diab Rep. 2021 Apr 13;21(6):17. doi: 10.1007/s11892-021-01388-2.

PURPOSE OF REVIEW: Prevalence of type 2 diabetes (T2D) and progression of complications differ between worldwide populations. While obesity is a major contributing risk factor, variations in physiological manifestations, e.g., developing T2D at lower body mass index in some...

Showing 73 to 83 of 83 entries