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A CRISPR/Cas9-based central processing unit to program complex logic computation in human cells.

Proceedings of the National Academy of Sciences of the United States of America

Kim H, Bojar D, Fussenegger M.
PMID: 30923122
Proc Natl Acad Sci U S A. 2019 Apr 09;116(15):7214-7219. doi: 10.1073/pnas.1821740116. Epub 2019 Mar 28.

Controlling gene expression with sophisticated logic gates has been and remains one of the central aims of synthetic biology. However, conventional implementations of biocomputers use central processing units (CPUs) assembled from multiple protein-based gene switches, limiting the programming flexibility...

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Kim H, Bojar D, Fussenegger M. A CRISPR/Cas9-based central processing unit to program complex logic computation in human cells. Proc Natl Acad Sci U S A. 2019;116(15):7214-7219doi: 10.1073/pnas.1821740116.
Kim, H., Bojar, D., & Fussenegger, M. (2019). A CRISPR/Cas9-based central processing unit to program complex logic computation in human cells. Proceedings of the National Academy of Sciences of the United States of America, 116(15), 7214-7219. https://doi.org/10.1073/pnas.1821740116
Kim, Hyojin, et al. "A CRISPR/Cas9-based central processing unit to program complex logic computation in human cells." Proceedings of the National Academy of Sciences of the United States of America vol. 116,15 (2019): 7214-7219. doi: https://doi.org/10.1073/pnas.1821740116
Kim H, Bojar D, Fussenegger M. A CRISPR/Cas9-based central processing unit to program complex logic computation in human cells. Proc Natl Acad Sci U S A. 2019 Apr 09;116(15):7214-7219. doi: 10.1073/pnas.1821740116. Epub 2019 Mar 28. PMID: 30923122; PMCID: PMC6462112.
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Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing.

Cell reports

Garcia B, Lee J, Edraki A, Hidalgo-Reyes Y, Erwood S, Mir A, Trost CN, Seroussi U, Stanley SY, Cohn RD, Claycomb JM, Sontheimer EJ, Maxwell KL, Davidson AR.
PMID: 31722192
Cell Rep. 2019 Nov 12;29(7):1739-1746.e5. doi: 10.1016/j.celrep.2019.10.017.

CRISPR-Cas9 systems provide powerful tools for genome editing. However, optimal employment of this technology will require control of Cas9 activity so that the timing, tissue specificity, and accuracy of editing may be precisely modulated. Anti-CRISPR proteins, which are small,...

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Garcia B, Lee J, Edraki A, et al. Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing. Cell Rep. 2019;29(7):1739-1746.e5doi: 10.1016/j.celrep.2019.10.017.
Garcia, B., Lee, J., Edraki, A., Hidalgo-Reyes, Y., Erwood, S., Mir, A., Trost, C. N., Seroussi, U., Stanley, S. Y., Cohn, R. D., Claycomb, J. M., Sontheimer, E. J., Maxwell, K. L., & Davidson, A. R. (2019). Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing. Cell reports, 29(7), 1739-1746.e5. https://doi.org/10.1016/j.celrep.2019.10.017
Garcia, Bianca, et al. "Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing." Cell reports vol. 29,7 (2019): 1739-1746.e5. doi: https://doi.org/10.1016/j.celrep.2019.10.017
Garcia B, Lee J, Edraki A, Hidalgo-Reyes Y, Erwood S, Mir A, Trost CN, Seroussi U, Stanley SY, Cohn RD, Claycomb JM, Sontheimer EJ, Maxwell KL, Davidson AR. Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing. Cell Rep. 2019 Nov 12;29(7):1739-1746.e5. doi: 10.1016/j.celrep.2019.10.017. PMID: 31722192; PMCID: PMC6910239.
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3D bioprinting of cell-laden electroconductive MXene nanocomposite bioinks.

Nanoscale

Rastin H, Zhang B, Mazinani A, Hassan K, Bi J, Tung TT, Losic D.
PMID: 32579663
Nanoscale. 2020 Aug 06;12(30):16069-16080. doi: 10.1039/d0nr02581j.

MXenes, a new family of burgeoning two-dimensional (2D) transition metal carbides/nitrides, have been extensively explored in recent years owing to their outstanding properties such as a large specific surface area, high electrical conductivity, low toxicity, and biodegradability. Numerous efforts...

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Rastin H, Zhang B, Mazinani A, et al. 3D bioprinting of cell-laden electroconductive MXene nanocomposite bioinks. Nanoscale. 2020;12(30):16069-16080doi: 10.1039/d0nr02581j.
Rastin, H., Zhang, B., Mazinani, A., Hassan, K., Bi, J., Tung, T. T., & Losic, D. (2020). 3D bioprinting of cell-laden electroconductive MXene nanocomposite bioinks. Nanoscale, 12(30), 16069-16080. https://doi.org/10.1039/d0nr02581j
Rastin, Hadi, et al. "3D bioprinting of cell-laden electroconductive MXene nanocomposite bioinks." Nanoscale vol. 12,30 (2020): 16069-16080. doi: https://doi.org/10.1039/d0nr02581j
Rastin H, Zhang B, Mazinani A, Hassan K, Bi J, Tung TT, Losic D. 3D bioprinting of cell-laden electroconductive MXene nanocomposite bioinks. Nanoscale. 2020 Aug 06;12(30):16069-16080. doi: 10.1039/d0nr02581j. PMID: 32579663.
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Showing 13 to 15 of 15 entries