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Showing 13 to 15 of 15 entries
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Review: cytokines and the pathogenesis of multiple sclerosis.

Journal of neuroscience research

Navikas V, Link H.
PMID: 8872892
J Neurosci Res. 1996 Aug 15;45(4):322-33. doi: 10.1002/(SICI)1097-4547(19960815)45:4<322::AID-JNR1>3.0.CO;2-B.

Perivascular accumulation of mononuclear cells (MNCs) in the central nervous system (CNS) and high levels of myelin autoantigen-reactive T cells in blood and further enriched in cerebrospinal fluid (CSF) are characteristic for multiple sclerosis (MS) and suggest a role...

Immunological processes related to cognitive impairment in MS.

Acta neurologica Scandinavica

Berger T.
PMID: 27580904
Acta Neurol Scand. 2016 Sep;134:34-8. doi: 10.1111/ane.12647.

In this review, the immune-to-brain communication pathways are briefly summarized, with emphasis on the impact of immune cells and their mediators on learning, memory and other cognitive domains. Further, the acute response of the central nervous system to peripherally...

Progressive multiple sclerosis: from pathogenic mechanisms to treatment.

Brain : a journal of neurology

Correale J, Gaitán MI, Ysrraelit MC, Fiol MP.
PMID: 27794524
Brain. 2017 Mar 01;140(3):527-546. doi: 10.1093/brain/aww258.

During the past decades, better understanding of relapsing-remitting multiple sclerosis disease mechanisms have led to the development of several disease-modifying therapies, reducing relapse rates and severity, through immune system modulation or suppression. In contrast, current therapeutic options for progressive...

Showing 13 to 15 of 15 entries