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Overexpression of KIR inhibitory ligands (HLA-I) determines that immunosurveillance of myeloma depends on diverse and strong NK cell licensing.

Oncoimmunology

Martínez-Sánchez MV, Periago A, Legaz I, Gimeno L, Mrowiec A, Montes-Barqueros NR, Campillo JA, Bolarin JM, Bernardo MV, López-Álvarez MR, González C, García-Garay MC, Muro M, Cabañas-Perianes V, Fuster JL, García-Alonso AM, Moraleda JM, Álvarez-Lopez MR, Minguela A.
PMID: 27141379
Oncoimmunology. 2015 Oct 29;5(4):e1093721. doi: 10.1080/2162402X.2015.1093721. eCollection 2016 Apr.

Missing self recognition makes cancer sensitive to natural killer cell (NKc) reactivity. However, this model disregards the NKc licensing effect, which highly increases NKc reactivity through interactions of inhibitory killer cell immunoglobulin-like receptors (iKIR) with their cognate HLA-I ligands....

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Martínez-Sánchez MV, Periago A, Legaz I, et al. Overexpression of KIR inhibitory ligands (HLA-I) determines that immunosurveillance of myeloma depends on diverse and strong NK cell licensing. Oncoimmunology. 2015;5(4):e1093721doi: 10.1080/2162402X.2015.1093721.
Martínez-Sánchez, M. V., Periago, A., Legaz, I., Gimeno, L., Mrowiec, A., Montes-Barqueros, N. R., Campillo, J. A., Bolarin, J. M., Bernardo, M. V., López-Álvarez, M. R., González, C., García-Garay, M. C., Muro, M., Cabañas-Perianes, V., Fuster, J. L., García-Alonso, A. M., Moraleda, J. M., Álvarez-Lopez, M. R., & Minguela, A. (2016). Overexpression of KIR inhibitory ligands (HLA-I) determines that immunosurveillance of myeloma depends on diverse and strong NK cell licensing. Oncoimmunology, 5(4), e1093721. https://doi.org/10.1080/2162402X.2015.1093721
Martínez-Sánchez, María V, et al. "Overexpression of KIR inhibitory ligands (HLA-I) determines that immunosurveillance of myeloma depends on diverse and strong NK cell licensing." Oncoimmunology vol. 5,4 (2016): e1093721. doi: https://doi.org/10.1080/2162402X.2015.1093721
Martínez-Sánchez MV, Periago A, Legaz I, Gimeno L, Mrowiec A, Montes-Barqueros NR, Campillo JA, Bolarin JM, Bernardo MV, López-Álvarez MR, González C, García-Garay MC, Muro M, Cabañas-Perianes V, Fuster JL, García-Alonso AM, Moraleda JM, Álvarez-Lopez MR, Minguela A. Overexpression of KIR inhibitory ligands (HLA-I) determines that immunosurveillance of myeloma depends on diverse and strong NK cell licensing. Oncoimmunology. 2015 Oct 29;5(4):e1093721. doi: 10.1080/2162402X.2015.1093721. eCollection 2016 Apr. PMID: 27141379; PMCID: PMC4839374.
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NKG2D Polymorphism in Melanoma Patients from Southeastern Spain.

Cancers

Gimeno L, Martínez-Banaclocha H, Bernardo MV, Bolarin JM, Marín L, López-Hernández R, López-Alvarez MR, Moya-Quiles MR, Muro M, Frias-Iniesta JF, Martínez-Escribano J, Alvarez-López MR, Minguela A, Campillo JA.
PMID: 30925758
Cancers (Basel). 2019 Mar 28;11(4). doi: 10.3390/cancers11040438.

BACKGROUND: Natural killer (NK) and CD8+ T cells are involved in the immune response against melanoma. C-Type lectin-like NK cell receptors are located in the Natural Killer Complex (NKC) region 12p13.2-p12.3 and play a critical role in regulating the...

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Gimeno L, Martínez-Banaclocha H, Bernardo MV, et al. NKG2D Polymorphism in Melanoma Patients from Southeastern Spain. Cancers (Basel). 2019;11(4)doi: 10.3390/cancers11040438.
Gimeno, L., Martínez-Banaclocha, H., Bernardo, M. V., Bolarin, J. M., Marín, L., López-Hernández, R., López-Alvarez, M. R., Moya-Quiles, M. R., Muro, M., Frias-Iniesta, J. F., Martínez-Escribano, J., Alvarez-López, M. R., Minguela, A., & Campillo, J. A. (2019). NKG2D Polymorphism in Melanoma Patients from Southeastern Spain. Cancers, 11(4), . https://doi.org/10.3390/cancers11040438
Gimeno, Lourdes, et al. "NKG2D Polymorphism in Melanoma Patients from Southeastern Spain." Cancers vol. 11,4 (2019). doi: https://doi.org/10.3390/cancers11040438
Gimeno L, Martínez-Banaclocha H, Bernardo MV, Bolarin JM, Marín L, López-Hernández R, López-Alvarez MR, Moya-Quiles MR, Muro M, Frias-Iniesta JF, Martínez-Escribano J, Alvarez-López MR, Minguela A, Campillo JA. NKG2D Polymorphism in Melanoma Patients from Southeastern Spain. Cancers (Basel). 2019 Mar 28;11(4). doi: 10.3390/cancers11040438. PMID: 30925758; PMCID: PMC6521179.
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Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline.

Frontiers in genetics

Cosín-Tomás M, Álvarez-López MJ, Companys-Alemany J, Kaliman P, González-Castillo C, Ortuño-Sahagún D, Pallàs M, Griñán-Ferré C.
PMID: 30619445
Front Genet. 2018 Dec 11;9:596. doi: 10.3389/fgene.2018.00596. eCollection 2018.

A growing body of research shows that epigenetic mechanisms are critically involved in normal and pathological aging. The Senescence-Accelerated Mouse Prone 8 (SAMP8) can be considered a useful tool to better understand the dynamics of the global epigenetic landscape...

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Cosín-Tomás M, Álvarez-López MJ, Companys-Alemany J, et al. Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline. Front Genet. 2018;9:596doi: 10.3389/fgene.2018.00596.
Cosín-Tomás, M., Álvarez-López, M. J., Companys-Alemany, J., Kaliman, P., González-Castillo, C., Ortuño-Sahagún, D., Pallàs, M., & Griñán-Ferré, C. (2018). Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline. Frontiers in genetics, 9596. https://doi.org/10.3389/fgene.2018.00596
Cosín-Tomás, Marta, et al. "Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline." Frontiers in genetics vol. 9 (2018): 596. doi: https://doi.org/10.3389/fgene.2018.00596
Cosín-Tomás M, Álvarez-López MJ, Companys-Alemany J, Kaliman P, González-Castillo C, Ortuño-Sahagún D, Pallàs M, Griñán-Ferré C. Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline. Front Genet. 2018 Dec 11;9:596. doi: 10.3389/fgene.2018.00596. eCollection 2018. PMID: 30619445; PMCID: PMC6297390.
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KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling.

Cancers

Gimeno L, Serrano-López EM, Campillo JA, Cánovas-Zapata MA, Acuña OS, García-Cózar F, Martínez-Sánchez MV, Martínez-Hernández MD, Soto-Ramírez MF, López-Cubillana P, Martínez-Escribano J, Martínez-García J, Corbalan-García S, Álvarez-López MR, Minguela A.
PMID: 33076479
Cancers (Basel). 2020 Oct 15;12(10). doi: 10.3390/cancers12102991.

Killer-cell immunoglobulin-like receptors (KIR) are expressed by natural killer (NK) and effector T cells. Although KIR+ T cells accumulate in oncologic patients, their role in cancer immune response remains elusive. This study explored the role of KIR+CD8+ T cells...

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Gimeno L, Serrano-López EM, Campillo JA, et al. KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling. Cancers (Basel). 2020;12(10)doi: 10.3390/cancers12102991.
Gimeno, L., Serrano-López, E. M., Campillo, J. A., Cánovas-Zapata, M. A., Acuña, O. S., García-Cózar, F., Martínez-Sánchez, M. V., Martínez-Hernández, M. D., Soto-Ramírez, M. F., López-Cubillana, P., Martínez-Escribano, J., Martínez-García, J., Corbalan-García, S., Álvarez-López, M. R., & Minguela, A. (2020). KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling. Cancers, 12(10), . https://doi.org/10.3390/cancers12102991
Gimeno, Lourdes, et al. "KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling." Cancers vol. 12,10 (2020). doi: https://doi.org/10.3390/cancers12102991
Gimeno L, Serrano-López EM, Campillo JA, Cánovas-Zapata MA, Acuña OS, García-Cózar F, Martínez-Sánchez MV, Martínez-Hernández MD, Soto-Ramírez MF, López-Cubillana P, Martínez-Escribano J, Martínez-García J, Corbalan-García S, Álvarez-López MR, Minguela A. KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling. Cancers (Basel). 2020 Oct 15;12(10). doi: 10.3390/cancers12102991. PMID: 33076479; PMCID: PMC7650600.
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Mental health benefits of a 1-week intensive multimodal group program for adolescents with multiple adverse childhood experiences.

Child abuse & neglect

Roque-Lopez S, Llanez-Anaya E, Álvarez-López MJ, Everts M, Fernández D, Davidson RJ, Kaliman P.
PMID: 34628152
Child Abuse Negl. 2021 Dec;122:105349. doi: 10.1016/j.chiabu.2021.105349. Epub 2021 Oct 07.

BACKGROUND: Adverse childhood experiences (ACEs) are associated with a wide range of diseases, unsafe behavior and shorter life expectancy. However, there is scarce evidence on effective interventions for children or adolescents who report multiple ACEs, including abuse, neglect and...

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Roque-Lopez S, Llanez-Anaya E, Álvarez-López MJ, et al. Mental health benefits of a 1-week intensive multimodal group program for adolescents with multiple adverse childhood experiences. Child Abuse Negl. 2021;122:105349doi: 10.1016/j.chiabu.2021.105349.
Roque-Lopez, S., Llanez-Anaya, E., Álvarez-López, M. J., Everts, M., Fernández, D., Davidson, R. J., & Kaliman, P. (2021). Mental health benefits of a 1-week intensive multimodal group program for adolescents with multiple adverse childhood experiences. Child abuse & neglect, 122105349. https://doi.org/10.1016/j.chiabu.2021.105349
Roque-Lopez, Susana, et al. "Mental health benefits of a 1-week intensive multimodal group program for adolescents with multiple adverse childhood experiences." Child abuse & neglect vol. 122 (2021): 105349. doi: https://doi.org/10.1016/j.chiabu.2021.105349
Roque-Lopez S, Llanez-Anaya E, Álvarez-López MJ, Everts M, Fernández D, Davidson RJ, Kaliman P. Mental health benefits of a 1-week intensive multimodal group program for adolescents with multiple adverse childhood experiences. Child Abuse Negl. 2021 Dec;122:105349. doi: 10.1016/j.chiabu.2021.105349. Epub 2021 Oct 07. PMID: 34628152; PMCID: PMC8627589.
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Showing 1 to 5 of 5 entries