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Development and Validation of HPLC Method for the Simultaneous Determination of Five Food Additives and Caffeine in Soft Drinks.

International journal of analytical chemistry

Aşçı B, Dinç Zor Ş, Aksu Dönmez Ö.
PMID: 26989415
Int J Anal Chem. 2016;2016:2879406. doi: 10.1155/2016/2879406. Epub 2016 Feb 17.

Box-Behnken design was applied to optimize high performance liquid chromatography (HPLC) conditions for the simultaneous determination of potassium sorbate, sodium benzoate, carmoisine, allura red, ponceau 4R, and caffeine in commercial soft drinks. The experimental variables chosen were pH (6.0-7.0),...

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