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Showing 1 to 4 of 4 entries
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Biomarkers in neonates receiving potential nephrotoxic drugs.

European review for medical and pharmacological sciences

Sridharan K, Al Jufairi M, Al Segai O, Al Ansari E, Hashem Ahmed H, Husain Shaban G, Malalla Z, Al Marzooq R, Al Madhoob A, Saeed Tabbara K.
PMID: 34859872
Eur Rev Med Pharmacol Sci. 2021 Nov;25(22):7078-7088. doi: 10.26355/eurrev_202111_27260.

OBJECTIVE: Novel biomarkers, such as kidney injury molecule-1 (KIM-1), cystatin, and neutrophil gelatinase-associated lipocalin (NGAL) were shown to predict acute kidney injury (AKI) earlier than serum creatinine in critically ill. We carried out the present study to evaluate these...

Intravenous acetaminophen (at 15 mg/kg/dose every 6 hours) in critically ill preterm neonates with patent ductus arteriosus: A prospective study.

Journal of clinical pharmacy and therapeutics

Sridharan K, Al Jufairi M, Al Ansari E, Al Marzooq R, Hubail Z, Hasan SJR, Al Madhoob A.
PMID: 33638909
J Clin Pharm Ther. 2021 Aug;46(4):1010-1019. doi: 10.1111/jcpt.13384. Epub 2021 Feb 27.

WHAT IS KNOWN AND OBJECTIVES: Acetaminophen has been increasingly used in treating patent ductus arteriosus (PDA) in preterm neonates. Variations were observed in the dosing regimen of acetaminophen across the studies. There is hardly any data available for a...

Evaluation of urinary acetaminophen metabolites and its association with the genetic polymorphisms of the metabolising enzymes, and serum acetaminophen concentrations in preterm neonates with patent ductus arteriosus.

Xenobiotica; the fate of foreign compounds in biological systems

Sridharan K, Al Jufairi M, Al Ansari E, Jasim A, Eltayeb Diab D, Al Marzooq R, Al Madhoob A.
PMID: 34529545
Xenobiotica. 2021 Nov;51(11):1335-1342. doi: 10.1080/00498254.2021.1982070. Epub 2021 Sep 28.

Acetaminophen is gaining importance as a first-line drug for treating patent ductus arteriosus (PDA) in neonates. Predominant metabolites of acetaminophen in preterm neonates vary from that of adults; and the drug is predominantly metabolised by conjugation and partly by...

Biomarkers in neonates receiving potential nephrotoxic drugs.

European review for medical and pharmacological sciences

Sridharan K, Al Jufairi M, Al Segai O, Al Ansari E, Hashem Ahmed H, Husain Shaban G, Malalla Z, Al Marzooq R, Al Madhoob A, Saeed Tabbara K.
PMID: 34859872
Eur Rev Med Pharmacol Sci. 2021 Nov;25(22):7078-7088. doi: 10.26355/eurrev_202111_27260.

OBJECTIVE: Novel biomarkers, such as kidney injury molecule-1 (KIM-1), cystatin, and neutrophil gelatinase-associated lipocalin (NGAL) were shown to predict acute kidney injury (AKI) earlier than serum creatinine in critically ill. We carried out the present study to evaluate these...

Showing 1 to 4 of 4 entries