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Showing 1 to 12 of 55 entries
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Expression of the .

Frontiers in plant science

Ghneim-Herrera T, Selvaraj MG, Meynard D, Fabre D, Peña A, Ben Romdhane W, Ben Saad R, Ogawa S, Rebolledo MC, Ishitani M, Tohme J, Al-Doss A, Guiderdoni E, Hassairi A.
PMID: 28659945
Front Plant Sci. 2017 Jun 12;8:994. doi: 10.3389/fpls.2017.00994. eCollection 2017.

We evaluated the yields of

Donor derived leukemia in allogeneic transplantation.

Leukemia & lymphoma

Aldoss I, Clark M, Marcucci G, Forman SJ.
PMID: 34713775
Leuk Lymphoma. 2021 Dec;62(12):2823-2830. doi: 10.1080/10428194.2021.1929966. Epub 2021 Oct 29.

Allogeneic hematopoietic cell transplantation (alloHCT) is a curative option for the treatment of eligible patients with hematological malignancies. This modality confers a risk for life-threatening complications, including the rare and underdiagnosed complication of donor-derived leukemia (DDL). DDL differs from...

Analysis of Salinity Tolerance in Tomato Introgression Lines Based on Morpho-Physiological and Molecular Traits.

Plants (Basel, Switzerland)

Ali AAM, Romdhane WB, Tarroum M, Al-Dakhil M, Al-Doss A, Alsadon AA, Hassairi A.
PMID: 34961065
Plants (Basel). 2021 Nov 26;10(12). doi: 10.3390/plants10122594.

The development of salt-tolerant tomato genotypes is a basic requirement to overcome the challenges of tomato production under salinity in the field or soil-free farming. Two groups of eight tomato introgression lines (ILs) each, were evaluated for salinity tolerance....

Venetoclax and hypomethylating agents in FLT3-mutated acute myeloid leukemia.

American journal of hematology

Aldoss I, Zhang J, Mei M, Al Malki MM, Arslan S, Ngo D, Aribi A, Ali H, Sandhu K, Salhotra A, Koller P, Khaled S, Artz A, Snyder D, Nakamura R, Forman SJ, Stein AS, Marcucci G, Pullarkat V.
PMID: 32628327
Am J Hematol. 2020 Jul 06; doi: 10.1002/ajh.25929. Epub 2020 Jul 06.

FMS-like tyrosine kinase 3 (FLT3) mutations are prevalent in acute myeloid leukemia (AML), and their presence confers adverse risk. FLT3-mutated (FLT3m) AML is a challenging leukemia to manage, particularly in older and unfit patients as well as patients with...

Venetoclax and hypomethylating agents yield high response rates and favourable transplant outcomes in patients with newly diagnosed acute myeloid leukaemia.

British journal of haematology

Salhotra A, Tsai NC, Zhang J, Ngo D, Aribi A, Sandhu K, Ball B, Al-Malki M, Ali H, Koller P, Artz A, Forman S, Nakamura R, Stein A, Marcucci G, Aldoss I, Pullarkat V.
PMID: 34931310
Br J Haematol. 2021 Dec 21; doi: 10.1111/bjh.17996. Epub 2021 Dec 21.

No abstract available.

New Mammalian Glycerol-3-Phosphate Phosphatase: Role in β-Cell, Liver and Adipocyte Metabolism.

Frontiers in endocrinology

Possik E, Al-Mass A, Peyot ML, Ahmad R, Al-Mulla F, Madiraju SRM, Prentki M.
PMID: 34326816
Front Endocrinol (Lausanne). 2021 Jul 13;12:706607. doi: 10.3389/fendo.2021.706607. eCollection 2021.

Cardiometabolic diseases, including type 2 diabetes, obesity and non-alcoholic fatty liver disease, have enormous impact on modern societies worldwide. Excess nutritional burden and nutri-stress together with sedentary lifestyles lead to these diseases. Deranged glucose, fat, and energy metabolism is...

Have any strategies in Ph-like ALL been shown to be effective?.

Best practice & research. Clinical haematology

Aldoss I, Advani AS.
PMID: 33762097
Best Pract Res Clin Haematol. 2021 Mar;34(1):101242. doi: 10.1016/j.beha.2021.101242. Epub 2021 Jan 11.

Philadelphia-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk subset of B-cell ALL characterized by high rates of treatment failure. Unsatisfactory outcomes with frontline therapy in adults with Ph-like ALL have been observed irrespective of the employed regimen, including...

Analysis of Salinity Tolerance in Tomato Introgression Lines Based on Morpho-Physiological and Molecular Traits.

Plants (Basel, Switzerland)

Ali AAM, Romdhane WB, Tarroum M, Al-Dakhil M, Al-Doss A, Alsadon AA, Hassairi A.
PMID: 34961065
Plants (Basel). 2021 Nov 26;10(12). doi: 10.3390/plants10122594.

The development of salt-tolerant tomato genotypes is a basic requirement to overcome the challenges of tomato production under salinity in the field or soil-free farming. Two groups of eight tomato introgression lines (ILs) each, were evaluated for salinity tolerance....

Harnessing the Rhizosphere of the Halophyte Grass .

Plants (Basel, Switzerland)

Tarroum M, Ben Romdhane W, Ali AAM, Al-Qurainy F, Al-Doss A, Fki L, Hassairi A.
PMID: 33923476
Plants (Basel). 2021 Apr 16;10(4). doi: 10.3390/plants10040784.

Hydroponic systems have gained interest and are increasingly used in hot and dry desert areas. Numbers of benefits are offered by hydroponic systems such as the ability to save water, enhance nutrients use efficiency, easy environmental control, and prevention...

Long-term follow-up of patients with poor-risk acute leukemia treated on a phase 2 trial undergoing intensified conditioning regimen prior to allogeneic hematopoietic cell transplantation.

Leukemia & lymphoma

Salhotra A, Yang D, Mokhtari S, Hui S, Al Malki MM, Armenian S, Sigala B, Aldoss I, Pullarkat V, Forman S, Marcucci G, Nakamura R, Artz A, Wong J, Stein A.
PMID: 34879769
Leuk Lymphoma. 2021 Dec 09;1-7. doi: 10.1080/10428194.2021.2012661. Epub 2021 Dec 09.

Patients with acute leukemia who undergo allogenic hematopoietic cell transplantation with active disease have high rates of relapse and poor overall survival (OS) post-transplant compared to patients undergoing HCT in remission. Here, we report the long-term outcomes in 32...

Generation and Characterization of Nanobodies Against Tomato Leaf Curl Sudan Virus.

Plant disease

Zakri AM, Al-Doss AA, Ali AA, Samara EM, Ahmed BS, Al-Saleh MA, Idris AM, Abdalla OA, Sack M.
PMID: 33599515
Plant Dis. 2021 Sep;105(9):2410-2417. doi: 10.1094/PDIS-11-20-2407-RE. Epub 2021 Oct 19.

Begomoviruses infect food, fiber, and vegetable crop plants, including tomato, potato, bean, cotton, cucumber, and pumpkin, and damage many economically important crop plants worldwide. Tomato leaf curl Sudan virus (ToLCSDV) is the most widespread tomato-infecting begomovirus in Saudi Arabia....

Will immunotherapy lead to a breakthrough in the treatment of older adults with ALL?.

Best practice & research. Clinical haematology

Aldoss I, Advani A, Pullarkat V.
PMID: 34865691
Best Pract Res Clin Haematol. 2021 Dec;34(4):101319. doi: 10.1016/j.beha.2021.101319. Epub 2021 Oct 22.

Historically, older adults with B-cell acute lymphoblastic leukemia (ALL) have done poorly with chemotherapy-based treatment. Therefore, new innovative approaches are urgently needed to improve outcomes for this population. CD19-targeted immunotherapies such as blinatumomab and chimeric antigen receptor (CAR) T...

Showing 1 to 12 of 55 entries