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Showing 1 to 12 of 42 entries
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Mu opioid receptor (OPRM1) as a predictor of treatment outcome in opiate-dependent individuals of Arab descent.

Pharmacogenomics and personalized medicine

Al-Eitan LN, Jaradat SA, Su SY, Tay GK, Hulse GK.
PMID: 23226066
Pharmgenomics Pers Med. 2012;5:99-111. doi: 10.2147/PGPM.S33351. Epub 2012 Sep 07.

BACKGROUND: A number of research studies on the genetics of opiate dependence have focused on the μ-opioid receptor (OPRM1), which is a primary target for opiates. This study aims to identify genetic polymorphisms within the OPRM1 gene involved in...

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Al-Eitan LN, Jaradat SA, Su SY, et al. Mu opioid receptor (OPRM1) as a predictor of treatment outcome in opiate-dependent individuals of Arab descent. Pharmgenomics Pers Med. 2012;5:99-111doi: 10.2147/PGPM.S33351.
Al-Eitan, L. N., Jaradat, S. A., Su, S. Y., Tay, G. K., & Hulse, G. K. (2012). Mu opioid receptor (OPRM1) as a predictor of treatment outcome in opiate-dependent individuals of Arab descent. Pharmacogenomics and personalized medicine, 599-111. https://doi.org/10.2147/PGPM.S33351
Al-Eitan, Laith N, et al. "Mu opioid receptor (OPRM1) as a predictor of treatment outcome in opiate-dependent individuals of Arab descent." Pharmacogenomics and personalized medicine vol. 5 (2012): 99-111. doi: https://doi.org/10.2147/PGPM.S33351
Al-Eitan LN, Jaradat SA, Su SY, Tay GK, Hulse GK. Mu opioid receptor (OPRM1) as a predictor of treatment outcome in opiate-dependent individuals of Arab descent. Pharmgenomics Pers Med. 2012;5:99-111. doi: 10.2147/PGPM.S33351. Epub 2012 Sep 07. PMID: 23226066; PMCID: PMC3513232.
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The Impact of Potassium Channel Gene Polymorphisms on Antiepileptic Drug Responsiveness in Arab Patients with Epilepsy.

Journal of personalized medicine

Al-Eitan LN, Al-Dalalah IM, Elshammari AK, Khreisat WH, Almasri AY.
PMID: 30441785
J Pers Med. 2018 Nov 14;8(4). doi: 10.3390/jpm8040037.

This study aims to investigate the effects of the three potassium channel genes

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Al-Eitan LN, Al-Dalalah IM, Elshammari AK, et al. The Impact of Potassium Channel Gene Polymorphisms on Antiepileptic Drug Responsiveness in Arab Patients with Epilepsy. J Pers Med. 2018;8(4)doi: 10.3390/jpm8040037.
Al-Eitan, L. N., Al-Dalalah, I. M., Elshammari, A. K., Khreisat, W. H., & Almasri, A. Y. (2018). The Impact of Potassium Channel Gene Polymorphisms on Antiepileptic Drug Responsiveness in Arab Patients with Epilepsy. Journal of personalized medicine, 8(4), . https://doi.org/10.3390/jpm8040037
Al-Eitan, Laith N, et al. "The Impact of Potassium Channel Gene Polymorphisms on Antiepileptic Drug Responsiveness in Arab Patients with Epilepsy." Journal of personalized medicine vol. 8,4 (2018). doi: https://doi.org/10.3390/jpm8040037
Al-Eitan LN, Al-Dalalah IM, Elshammari AK, Khreisat WH, Almasri AY. The Impact of Potassium Channel Gene Polymorphisms on Antiepileptic Drug Responsiveness in Arab Patients with Epilepsy. J Pers Med. 2018 Nov 14;8(4). doi: 10.3390/jpm8040037. PMID: 30441785; PMCID: PMC6313615.
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Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function.

Clinical, cosmetic and investigational dermatology

Al-Eitan LN, Aljamal HA, Alkhatib RQ.
PMID: 30643445
Clin Cosmet Investig Dermatol. 2018 Dec 31;12:11-21. doi: 10.2147/CCID.S190359. eCollection 2019.

BACKGROUND: Sunscreens are one of the most widely used products among cosmetics and personal care products. Recent studies have shown that some of sunscreen formulations may contain toxic, carcinogenic, or even nonallowed chemicals that may affect skin, cells, and...

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Al-Eitan LN, Aljamal HA, Alkhatib RQ. Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function. Clin Cosmet Investig Dermatol. 2018;12:11-21doi: 10.2147/CCID.S190359.
Al-Eitan, L. N., Aljamal, H. A., & Alkhatib, R. Q. (2019). Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function. Clinical, cosmetic and investigational dermatology, 1211-21. https://doi.org/10.2147/CCID.S190359
Al-Eitan, Laith N, et al. "Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function." Clinical, cosmetic and investigational dermatology vol. 12 (2019): 11-21. doi: https://doi.org/10.2147/CCID.S190359
Al-Eitan LN, Aljamal HA, Alkhatib RQ. Gas chromatographic-mass spectrometric analysis of sunscreens and their effects on mice liver and kidney enzyme function. Clin Cosmet Investig Dermatol. 2018 Dec 31;12:11-21. doi: 10.2147/CCID.S190359. eCollection 2019. PMID: 30643445; PMCID: PMC6319425.
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Impact of .

Genes

Al-Eitan LN, Almasri AY, Khasawneh RH.
PMID: 30486437
Genes (Basel). 2018 Nov 27;9(12). doi: 10.3390/genes9120578.

Warfarin is an oral anticoagulant frequently used in the treatment of different cardiovascular diseases. Genetic polymorphisms in the

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Al-Eitan LN, Almasri AY, Khasawneh RH. Impact of . Genes (Basel). 2018;9(12)doi: 10.3390/genes9120578.
Al-Eitan, L. N., Almasri, A. Y., & Khasawneh, R. H. (2018). Impact of . Genes, 9(12), . https://doi.org/10.3390/genes9120578
Al-Eitan, Laith N, et al. "Impact of ." Genes vol. 9,12 (2018). doi: https://doi.org/10.3390/genes9120578
Al-Eitan LN, Almasri AY, Khasawneh RH. Impact of . Genes (Basel). 2018 Nov 27;9(12). doi: 10.3390/genes9120578. PMID: 30486437; PMCID: PMC6316567.
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Application of Gas Chromatography-Mass Spectrometry for the Identification and Quantitation of Three Common Synthetic Cannabinoids in Seized Materials from the Jordanian Market.

ACS omega

Al-Eitan LN, Asa'ad AS, Battah AH, Aljamal HA.
PMID: 32149247
ACS Omega. 2020 Feb 21;5(8):4172-4180. doi: 10.1021/acsomega.9b03881. eCollection 2020 Mar 03.

Synthetic cannabinoids (SCs) were developed to mimic the effects of Δ

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Al-Eitan LN, Asa'ad AS, Battah AH, et al. Application of Gas Chromatography-Mass Spectrometry for the Identification and Quantitation of Three Common Synthetic Cannabinoids in Seized Materials from the Jordanian Market. ACS Omega. 2020;5(8):4172-4180doi: 10.1021/acsomega.9b03881.
Al-Eitan, L. N., Asa'ad, A. S., Battah, A. H., & Aljamal, H. A. (2020). Application of Gas Chromatography-Mass Spectrometry for the Identification and Quantitation of Three Common Synthetic Cannabinoids in Seized Materials from the Jordanian Market. ACS omega, 5(8), 4172-4180. https://doi.org/10.1021/acsomega.9b03881
Al-Eitan, Laith N, et al. "Application of Gas Chromatography-Mass Spectrometry for the Identification and Quantitation of Three Common Synthetic Cannabinoids in Seized Materials from the Jordanian Market." ACS omega vol. 5,8 (2020): 4172-4180. doi: https://doi.org/10.1021/acsomega.9b03881
Al-Eitan LN, Asa'ad AS, Battah AH, Aljamal HA. Application of Gas Chromatography-Mass Spectrometry for the Identification and Quantitation of Three Common Synthetic Cannabinoids in Seized Materials from the Jordanian Market. ACS Omega. 2020 Feb 21;5(8):4172-4180. doi: 10.1021/acsomega.9b03881. eCollection 2020 Mar 03. PMID: 32149247; PMCID: PMC7057677.
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Variability of CYP2C8 Polymorphisms in Three Jordanian Populations: Circassians, Chechens and Jordanian-Arabs.

Journal of immigrant and minority health

Abudahab S, Hakooz N, Tobeh N, Gogazeh E, Gharaibeh M, Al-Eitan L, Zihlif M, Dajani R.
PMID: 34448113
J Immigr Minor Health. 2021 Aug 26; doi: 10.1007/s10903-021-01264-x. Epub 2021 Aug 26.

CYP2C8 is a member of Cytochrome P450 enzymes system. It plays an important role in metabolizing a wide range of exogenous and endogenous compounds. CYP2C8 is involved in the metabolism of more than 100 drugs, typical substrates include: anticancer...

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Abudahab S, Hakooz N, Tobeh N, et al. Variability of CYP2C8 Polymorphisms in Three Jordanian Populations: Circassians, Chechens and Jordanian-Arabs. J Immigr Minor Health. 2021;doi: 10.1007/s10903-021-01264-x.
Abudahab, S., Hakooz, N., Tobeh, N., Gogazeh, E., Gharaibeh, M., Al-Eitan, L., Zihlif, M., & Dajani, R. (2021). Variability of CYP2C8 Polymorphisms in Three Jordanian Populations: Circassians, Chechens and Jordanian-Arabs. Journal of immigrant and minority health, . https://doi.org/10.1007/s10903-021-01264-x
Abudahab, Sara, et al. "Variability of CYP2C8 Polymorphisms in Three Jordanian Populations: Circassians, Chechens and Jordanian-Arabs." Journal of immigrant and minority health vol. (2021). doi: https://doi.org/10.1007/s10903-021-01264-x
Abudahab S, Hakooz N, Tobeh N, Gogazeh E, Gharaibeh M, Al-Eitan L, Zihlif M, Dajani R. Variability of CYP2C8 Polymorphisms in Three Jordanian Populations: Circassians, Chechens and Jordanian-Arabs. J Immigr Minor Health. 2021 Aug 26; doi: 10.1007/s10903-021-01264-x. Epub 2021 Aug 26. PMID: 34448113.
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Identification of Differentially Methylated CpG Sites in Fibroblasts from Keloid Scars.

Biomedicines

Alghamdi MA, Wallace HJ, Melton PE, Moses EK, Stevenson A, Al-Eitan LN, Rea S, Duke JM, Danielsen PL, Prêle CM, Wood FM, Fear MW.
PMID: 32605309
Biomedicines. 2020 Jun 28;8(7). doi: 10.3390/biomedicines8070181.

As a part of an abnormal healing process of dermal injuries and irritation, keloid scars arise on the skin as benign fibroproliferative tumors. Although the etiology of keloid scarring remains unsettled, considerable recent evidence suggested that keloidogenesis may be...

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Alghamdi MA, Wallace HJ, Melton PE, et al. Identification of Differentially Methylated CpG Sites in Fibroblasts from Keloid Scars. Biomedicines. 2020;8(7)doi: 10.3390/biomedicines8070181.
Alghamdi, M. A., Wallace, H. J., Melton, P. E., Moses, E. K., Stevenson, A., Al-Eitan, L. N., Rea, S., Duke, J. M., Danielsen, P. L., Prêle, C. M., Wood, F. M., & Fear, M. W. (2020). Identification of Differentially Methylated CpG Sites in Fibroblasts from Keloid Scars. Biomedicines, 8(7), . https://doi.org/10.3390/biomedicines8070181
Alghamdi, Mansour A, et al. "Identification of Differentially Methylated CpG Sites in Fibroblasts from Keloid Scars." Biomedicines vol. 8,7 (2020). doi: https://doi.org/10.3390/biomedicines8070181
Alghamdi MA, Wallace HJ, Melton PE, Moses EK, Stevenson A, Al-Eitan LN, Rea S, Duke JM, Danielsen PL, Prêle CM, Wood FM, Fear MW. Identification of Differentially Methylated CpG Sites in Fibroblasts from Keloid Scars. Biomedicines. 2020 Jun 28;8(7). doi: 10.3390/biomedicines8070181. PMID: 32605309; PMCID: PMC7400180.
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Genetic association of .

OncoTargets and therapy

Al-Eitan LN, Rababa'h DM, Alghamdi MA, Khasawneh RH.
PMID: 31920325
Onco Targets Ther. 2019 Sep 26;12:7923-7928. doi: 10.2147/OTT.S220226. eCollection 2019.

PURPOSE: Breast cancer (BC) is a complex disease that is governed by several different environmental and inherited factors. There are many genes have been linked with BC development by screening specific genetic variants within these genes. In this study,...

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Al-Eitan LN, Rababa'h DM, Alghamdi MA, et al. Genetic association of . Onco Targets Ther. 2019;12:7923-7928doi: 10.2147/OTT.S220226.
Al-Eitan, L. N., Rababa'h, D. M., Alghamdi, M. A., & Khasawneh, R. H. (2019). Genetic association of . OncoTargets and therapy, 127923-7928. https://doi.org/10.2147/OTT.S220226
Al-Eitan, Laith N, et al. "Genetic association of ." OncoTargets and therapy vol. 12 (2019): 7923-7928. doi: https://doi.org/10.2147/OTT.S220226
Al-Eitan LN, Rababa'h DM, Alghamdi MA, Khasawneh RH. Genetic association of . Onco Targets Ther. 2019 Sep 26;12:7923-7928. doi: 10.2147/OTT.S220226. eCollection 2019. PMID: 31920325; PMCID: PMC6936298.
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The Association of IL-1 and HRAS Gene Polymorphisms with Breast Cancer Susceptibility in a Jordanian Population of Arab Descent: A Genotype-Phenotype Study.

Cancers

Al-Eitan LN, Al-Ahmad BH, Almomani FA.
PMID: 31979384
Cancers (Basel). 2020 Jan 23;12(2). doi: 10.3390/cancers12020283.

Breast cancer (BC) pathogenesis is poorly understood and not yet completely determined. BC susceptibility genes are responsible for 20% to 25% of breast cancer risk. The main objective of this study is to identify the genetic polymorphisms within the...

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Al-Eitan LN, Al-Ahmad BH, Almomani FA. The Association of IL-1 and HRAS Gene Polymorphisms with Breast Cancer Susceptibility in a Jordanian Population of Arab Descent: A Genotype-Phenotype Study. Cancers (Basel). 2020;12(2)doi: 10.3390/cancers12020283.
Al-Eitan, L. N., Al-Ahmad, B. H., & Almomani, F. A. (2020). The Association of IL-1 and HRAS Gene Polymorphisms with Breast Cancer Susceptibility in a Jordanian Population of Arab Descent: A Genotype-Phenotype Study. Cancers, 12(2), . https://doi.org/10.3390/cancers12020283
Al-Eitan, Laith N, et al. "The Association of IL-1 and HRAS Gene Polymorphisms with Breast Cancer Susceptibility in a Jordanian Population of Arab Descent: A Genotype-Phenotype Study." Cancers vol. 12,2 (2020). doi: https://doi.org/10.3390/cancers12020283
Al-Eitan LN, Al-Ahmad BH, Almomani FA. The Association of IL-1 and HRAS Gene Polymorphisms with Breast Cancer Susceptibility in a Jordanian Population of Arab Descent: A Genotype-Phenotype Study. Cancers (Basel). 2020 Jan 23;12(2). doi: 10.3390/cancers12020283. PMID: 31979384; PMCID: PMC7073163.
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Improving public stigma, sociocultural beliefs, and social identity for people with epilepsy in the Aseer region of Saudi Arabia.

Epilepsy & behavior reports

Abdel Ghaffar NF, Asiri RN, Al-Eitan LN, Alamri RS, Alshyarba RM, Alrefeidi FA, Asiri A, Alghamdi MA.
PMID: 33997759
Epilepsy Behav Rep. 2021 Apr 09;16:100442. doi: 10.1016/j.ebr.2021.100442. eCollection 2021.

Differences in the sociocultural practice and biases against people with epilepsy (PWE) largely contribute to the development of stigmatization. In this study, we evaluated factors that impact stigma for PWE involved in evolution and maintenance to report changes in...

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Abdel Ghaffar NF, Asiri RN, Al-Eitan LN, et al. Improving public stigma, sociocultural beliefs, and social identity for people with epilepsy in the Aseer region of Saudi Arabia. Epilepsy Behav Rep. 2021;16:100442doi: 10.1016/j.ebr.2021.100442.
Abdel Ghaffar, N. F., Asiri, R. N., Al-Eitan, L. N., Alamri, R. S., Alshyarba, R. M., Alrefeidi, F. A., Asiri, A., & Alghamdi, M. A. (2021). Improving public stigma, sociocultural beliefs, and social identity for people with epilepsy in the Aseer region of Saudi Arabia. Epilepsy & behavior reports, 16100442. https://doi.org/10.1016/j.ebr.2021.100442
Abdel Ghaffar, Nawal F, et al. "Improving public stigma, sociocultural beliefs, and social identity for people with epilepsy in the Aseer region of Saudi Arabia." Epilepsy & behavior reports vol. 16 (2021): 100442. doi: https://doi.org/10.1016/j.ebr.2021.100442
Abdel Ghaffar NF, Asiri RN, Al-Eitan LN, Alamri RS, Alshyarba RM, Alrefeidi FA, Asiri A, Alghamdi MA. Improving public stigma, sociocultural beliefs, and social identity for people with epilepsy in the Aseer region of Saudi Arabia. Epilepsy Behav Rep. 2021 Apr 09;16:100442. doi: 10.1016/j.ebr.2021.100442. eCollection 2021. PMID: 33997759; PMCID: PMC8094896.
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Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Al-Eitan LN, Al-Dalalah IM, Aljamal HA.
PMID: 31297029
Saudi Pharm J. 2019 Jul;27(5):731-737. doi: 10.1016/j.jsps.2019.04.009. Epub 2019 Apr 24.

BACKGROUND: Pharmacotherapy of epilepsy including antiepileptic drugs (AEDs) is one of the main treatment approaches. As a biological target, sodium channels (Nav channels) and glutamate receptor genes are playing a major role in the etiology and treatment of epilepsy.OBJECTIVE:...

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Al-Eitan LN, Al-Dalalah IM, Aljamal HA. Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility. Saudi Pharm J. 2019;27(5):731-737doi: 10.1016/j.jsps.2019.04.009.
Al-Eitan, L. N., Al-Dalalah, I. M., & Aljamal, H. A. (2019). Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 27(5), 731-737. https://doi.org/10.1016/j.jsps.2019.04.009
Al-Eitan, Laith N, et al. "Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility." Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society vol. 27,5 (2019): 731-737. doi: https://doi.org/10.1016/j.jsps.2019.04.009
Al-Eitan LN, Al-Dalalah IM, Aljamal HA. Effects of GRM4, SCN2A and SCN3B polymorphisms on antiepileptic drugs responsiveness and epilepsy susceptibility. Saudi Pharm J. 2019 Jul;27(5):731-737. doi: 10.1016/j.jsps.2019.04.009. Epub 2019 Apr 24. PMID: 31297029; PMCID: PMC6598501.
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WITHDRAWN: Evaluation of the factors that may contribute to the responsiveness of anti-epileptic treatments in pediatric patients, a study from Jordan.

Neuroscience research

Alrabadi NN, Al-Eitan LN, Al-Dalalah IM, Elshammari AK, Khreisat WH, Al-Quasmi MN, Aman HA, Mustafa MM, Qawasmeh MA.
PMID: 33387564
Neurosci Res. 2020 Dec 30; doi: 10.1016/j.neures.2020.07.013. Epub 2020 Dec 30.

This article has been withdrawn at the request of the editor and publisher. The publisher regrets that an error occurred which led to the publication of this paper, which had been rejected by the editor. This error bears no...

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Alrabadi NN, Al-Eitan LN, Al-Dalalah IM, et al. WITHDRAWN: Evaluation of the factors that may contribute to the responsiveness of anti-epileptic treatments in pediatric patients, a study from Jordan. Neurosci Res. 2020;doi: 10.1016/j.neures.2020.07.013.
Alrabadi, N. N., Al-Eitan, L. N., Al-Dalalah, I. M., Elshammari, A. K., Khreisat, W. H., Al-Quasmi, M. N., Aman, H. A., Mustafa, M. M., & Qawasmeh, M. A. (2020). WITHDRAWN: Evaluation of the factors that may contribute to the responsiveness of anti-epileptic treatments in pediatric patients, a study from Jordan. Neuroscience research, . https://doi.org/10.1016/j.neures.2020.07.013
Alrabadi, Nasr N, et al. "WITHDRAWN: Evaluation of the factors that may contribute to the responsiveness of anti-epileptic treatments in pediatric patients, a study from Jordan." Neuroscience research vol. (2020). doi: https://doi.org/10.1016/j.neures.2020.07.013
Alrabadi NN, Al-Eitan LN, Al-Dalalah IM, Elshammari AK, Khreisat WH, Al-Quasmi MN, Aman HA, Mustafa MM, Qawasmeh MA. WITHDRAWN: Evaluation of the factors that may contribute to the responsiveness of anti-epileptic treatments in pediatric patients, a study from Jordan. Neurosci Res. 2020 Dec 30; doi: 10.1016/j.neures.2020.07.013. Epub 2020 Dec 30. PMID: 33387564.
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Showing 1 to 12 of 42 entries