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Showing 1 to 12 of 58 entries
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Biopreservation of Sardinella longiceps and Penaeus monodon Using Protective Culture Streptococcus phocae PI 80 Isolated from Marine Shrimp Penaeus indicus.

Probiotics and antimicrobial proteins

Paari A, Paulraj K, Ramraj S, Neelkandan Y, Vellaiyan P, Siva P, Venkatesan A.
PMID: 26781574
Probiotics Antimicrob Proteins. 2011 Jun;3(2):103-11. doi: 10.1007/s12602-011-9070-y.

The influence of Streptococcus phocae PI80 on the shelf life of Sardinella longiceps and Penaeus monodon was investigated by measurement of microbial and chemical analysis after appraising the safety of the protective probiotic culture in wistar rat's model. The...

Synthesis and Electrochemical Behavior of Ceria Based Bi-Layer Films by Dip Coating Technique.

Journal of nanoscience and nanotechnology

Chinnu MK, Anand KV, Kumar RM, Alagesan T, Jayavel R.
PMID: 26328361
J Nanosci Nanotechnol. 2015 Jan;15(1):360-7. doi: 10.1166/jnn.2015.9521.

Ceria based bi-layer films of CeO2-CdS and CeO2-TiO2 were prepared by sol-gel based hydrothermal route combined with dip-coating. The synthesized samples were subjected to various characterizations such as X-ray diffraction, Field emission scanning electron microscopy, thermo-gravimetric analysis, UV-Vis absorption...

Weak hydrogen bonding and fluorous interactions in the chloride and bromide salts of 4-[(2,2,3,3-tetrafluoropropoxy)methyl]pyridinium.

Acta crystallographica. Section C, Structural chemistry

Lu N, Wei RJ, Lin KY, Alagesan M, Wen YS, Liu LK.
PMID: 28378719
Acta Crystallogr C Struct Chem. 2017 Apr 01;73:343-349. doi: 10.1107/S2053229617004016. Epub 2017 Mar 21.

Neutralization of 4-[(2,2,3,3-tetrafluoropropoxy)methyl]pyridine with hydrohalo acids HX (X = Cl and Br) yielded the pyridinium salts 4-[(2,2,3,3-tetrafluoropropoxy)methyl]pyridinium chloride, C

A Practical Guide to Approaching Biased Agonism at G Protein Coupled Receptors.

Frontiers in neuroscience

Gundry J, Glenn R, Alagesan P, Rajagopal S.
PMID: 28174517
Front Neurosci. 2017 Jan 24;11:17. doi: 10.3389/fnins.2017.00017. eCollection 2017.

Biased agonism, the ability of a receptor to differentially activate downstream signaling pathways depending on binding of a "biased" agonist compared to a "balanced" agonist, is a well-established paradigm for G protein-coupled receptor (GPCR) signaling. Biased agonists have the...

Comparison of Carotid Intima Media Thickness in Children of Patients with and without Premature Coronary Artery Disease.

Journal of clinical and diagnostic research : JCDR

Murali A, Mambatta AK, Ranganathan RR, Shanmugasundaram R, Deepalakshmi K.
PMID: 28208908
J Clin Diagn Res. 2016 Dec;10(12):OC29-OC31. doi: 10.7860/JCDR/2016/22625.9012. Epub 2016 Dec 01.

INTRODUCTION: Increased Carotid Intima Medial Thickness (CIMT) is associated with cardiovascular risk factors and vascular events like Coronary Artery Disease (CAD) and stroke.AIM: This study was designed to identify whether CIMT is increased in the children of parents with...

Effects of Sleep Deprivation on the Cognitive Performance of Nurses Working in Shift.

Journal of clinical and diagnostic research : JCDR

Kaliyaperumal D, Elango Y, Alagesan M, Santhanakrishanan I.
PMID: 28969117
J Clin Diagn Res. 2017 Aug;11(8):CC01-CC03. doi: 10.7860/JCDR/2017/26029.10324. Epub 2017 Aug 01.

INTRODUCTION: Sleep deprivation and altered circadian rhythm affects the cognitive performance of an individual. Quality of sleep is compromised in those who are frequently involved in extended working hours and shift work which is found to be more common...

A decade of change in susceptibility patterns of Gram-negative blood culture isolates: a single center study.

Germs

Alagesan M, Gopalakrishnan R, Panchatcharam SN, Dorairajan S, Mandayam Ananth T, Venkatasubramanian R.
PMID: 26405674
Germs. 2015 Sep 01;5(3):65-77. doi: 10.11599/germs.2015.1073. eCollection 2015 Sep.

BACKGROUND: Gram-negative bacteremia is one of the leading causes of mortality and morbidity in Indian hospitals. We hereby describe changing trends in Gram-negative isolates from blood cultures from a single center over a ten-year period.METHODS: Antibiotic susceptibility patterns were...

Extraction and Purification of R-Phycoerythrin Alpha Subunit from the Marine Red Algae .

Molecules (Basel, Switzerland)

Ulagesan S, Nam TJ, Choi YH.
PMID: 34770894
Molecules. 2021 Oct 27;26(21). doi: 10.3390/molecules26216479.

Phycoerythrin is a major light-harvesting pigment of red algae and cyanobacteria that is widely used as a fluorescent probe or as a colorant in the food and cosmetic industries. In this study, phycoerythrin was extracted from the red algae

Comparison of Single and Repeated Dosing of Anti-Inflammatory Human Umbilical Cord Mesenchymal Stromal Cells in a Mouse Model of Polymicrobial Sepsis.

Stem cell reviews and reports

Fazekas B, Alagesan S, Watson L, Ng O, Conroy CM, Català C, Andres MV, Negi N, Gerlach JQ, Hynes SO, Lozano F, Elliman SJ, Griffin MD.
PMID: 35013938
Stem Cell Rev Rep. 2022 Jan 10; doi: 10.1007/s12015-021-10323-7. Epub 2022 Jan 10.

Mesenchymal stromal cells (MSCs) ameliorate pre-clinical sepsis and sepsis-associated acute kidney injury (SA-AKI) but clinical trials of single-dose MSCs have not indicated robust efficacy. This study investigated immunomodulatory effects of a novel MSC product (CD362-selected human umbilical cord-derived MSCs...

Molecular dynamics simulation of Toxin-Antitoxin (TA) system in Acinetobacter baumannii to explore the novel mechanism for inhibition of cell wall biosynthesis: Zeta Toxin as an effective therapeutic target.

Journal of cellular biochemistry

Karthika A, Ramachandran B, Chitra J, Prabhu D, Rajamanikandan S, Veerapandiyan M, Jeyakanthan J.
PMID: 34448250
J Cell Biochem. 2021 Dec;122(12):1832-1847. doi: 10.1002/jcb.30137. Epub 2021 Aug 26.

The majority of bacteria and archaea contains Toxin-Antitoxin system (TA) that codes for the stable Toxin and unstable Antitoxin components forming a complex. The Antitoxin inhibits the catalytic activities of the Toxin. In general, the Antitoxin will be degraded...

Glycoproteome remodeling in MLL-rearranged B-cell precursor acute lymphoblastic leukemia.

Theranostics

Oliveira T, Zhang M, Joo EJ, Abdel-Azim H, Chen CW, Yang L, Chou CH, Qin X, Chen J, Alagesan K, Almeida A, Jacob F, Packer NH, von Itzstein M, Heisterkamp N, Kolarich D.
PMID: 34646384
Theranostics. 2021 Sep 21;11(19):9519-9537. doi: 10.7150/thno.65398. eCollection 2021.

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) with mixed-lineage leukemia gene rearrangement (MLL-r) is a poor-prognosis subtype for which additional therapeutic targets are urgently needed. Currently no multi-

Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer.

Proceedings of the National Academy of Sciences of the United States of America

Cheng DK, Oni TE, Thalappillil JS, Park Y, Ting HC, Alagesan B, Prasad NV, Addison K, Rivera KD, Pappin DJ, Van Aelst L, Tuveson DA.
PMID: 34021083
Proc Natl Acad Sci U S A. 2021 May 25;118(21). doi: 10.1073/pnas.2016904118.

Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with limited treatment options. Although activating mutations of the KRAS GTPase are the predominant dependency present in >90% of PDAC patients, targeting KRAS mutants directly has been challenging in PDAC. Similarly,...

Showing 1 to 12 of 58 entries