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Showing 1 to 12 of 44 entries
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Synthesis and molecular modeling of six novel monastrol analogues: evaluation of cytotoxicity and kinesin inhibitory activity against HeLa cell line.

Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences

Abnous K, Barati B, Mehri S, Masboghi Farimani MR, Alibolandi M, Mohammadpour F, Ghandadi M, Hadizadeh F.
PMID: 24355209
Daru. 2013 Dec 19;21(1):70. doi: 10.1186/2008-2231-21-70.

BACKGROUND AND THE PURPOSE OF THE STUDY: A common approach in cancer chemotherapy is development of drugs that interrupt the mitosis phase of cell division. Dimethylenastron is a known kinesin inhibitor. In this study, six novel dimethylenastron analogues (4a-f),...

Synthesis of novel 1,8-acridinediones derivatives: Investigation of MDR reversibility on breast cancer cell lines T47D and tamoxifen-resistant T47D.

Research in pharmaceutical sciences

Moallem SA, Dehghani N, Mehri S, Shahsavand Sh, Alibolandi M, Hadizadeh F.
PMID: 26600848
Res Pharm Sci. 2015 May-Jun;10(3):214-21.

Multi drug resistance (MDR) is a serious obstacle in the management of breast cancer. Therefore, overcoming MDR using novel anticancer agents is a top priority for medicinal chemists. It was found that dihydropyridines lacking calcium antagonistic activity (e.g acridinediones)...

Purification and Refolding of Overexpressed Human Basic Fibroblast Growth Factor in Escherichia coli.

Biotechnology research international

Alibolandi M, Mirzahoseini H.
PMID: 21837279
Biotechnol Res Int. 2011;2011:973741. doi: 10.4061/2011/973741. Epub 2011 Aug 03.

This work describes the integration of expanded bed adsorption (EBA) and adsorptive protein refolding operations used to recover purified and biologically active human basic fibroblast growth factor from inclusion bodies expressed in E. coli. Insoluble overexpressed human basic fibroblast...

A colorimetric gold nanoparticle aggregation assay for malathion based on target-induced hairpin structure assembly of complementary strands of aptamer.

Mikrochimica acta

Abnous K, Danesh NM, Ramezani M, Alibolandi M, Emrani AS, Lavaee P, Taghdisi SM.
PMID: 29594570
Mikrochim Acta. 2018 Mar 12;185(4):216. doi: 10.1007/s00604-018-2752-3.

The authors describe a method for the colorimetric determination of the pesticide malathion. It is based on the use of a hairpin structure consisting of a complementary strand of aptamer and a double-stranded DNA (dsDNA) structure to protect gold...

Corrigendum to "The chemotherapeutic potential of doxorubicin-loaded PEG-b-PLGA nanopolymersomes in mouse breast cancer model." [Eur. J. Pharm. Biopharm. 94 (2015) 521-531].

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Alibolandi M, Sadeghi F, Abnous K, Atyabi F, Ramezani M, Hadizadeh F.
PMID: 31470967
Eur J Pharm Biopharm. 2019 Sep;142:540. doi: 10.1016/j.ejpb.2019.02.005. Epub 2019 Aug 08.

No abstract available.

A simple and ultrasensitive metal-organic framework-based aptasensor for fluorescence detection of ethanolamine.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Khoshbin Z, Zamanian J, Davoodian N, Mohammad Danesh N, Ramezani M, Alibolandi M, Abnous K, Taghdisi SM.
PMID: 34739893
Spectrochim Acta A Mol Biomol Spectrosc. 2022 Feb 15;267:120488. doi: 10.1016/j.saa.2021.120488. Epub 2021 Oct 13.

In this research, a facile fluorescence aptasensor was designed for the ultrasensitive determination of ethanolamine (ETA) as an aliphatic amino alcohol molecule with harmful side effects for human health. Zeolitic imidazolate framework-8 (ZIF-8) as an efficient metal-organic framework was...

Design and synthesis of a star-like polymeric micelle modified with AS1411 aptamer for targeted delivery of camptothecin for cancer therapy.

International journal of pharmaceutics

Jabbari A, Yaghoobi E, Azizollahi H, Shojaee S, Ramezani M, Alibolandi M, Abnous K, Taghdisi SM.
PMID: 34871712
Int J Pharm. 2021 Dec 04;611:121346. doi: 10.1016/j.ijpharm.2021.121346. Epub 2021 Dec 04.

Improving of tumor targeting and decreasing side effects at normal cells of antitumor drugs are necessary to promote the cancer chemotherapy efficacy. Herein, we have synthesized a novel 21-arm star like diblock polymer of β-cyclodextrin-{poly(ε-caprolactone)-poly(2-aminoethylmethacrylate)}

Synthesis of block copolymers used in polymersome fabrication: Application in drug delivery.

Journal of controlled release : official journal of the Controlled Release Society

Hasannia M, Aliabadi A, Abnous K, Taghdisi SM, Ramezani M, Alibolandi M.
PMID: 34774891
J Control Release. 2021 Nov 11;341:95-117. doi: 10.1016/j.jconrel.2021.11.010. Epub 2021 Nov 11.

Amphiphilic block copolymers are common materials used for the fabrication of various nanostructures with biomedical applications including nanocapsules, nanospheres, micelles and polymeric vesicles. According to the literature, polymersomes have several advantages compared to other nanostructures used as drug delivery...

Fabrication of anionic dextran-coated micelles for aptamer targeted delivery of camptothecin and survivin-shRNA to colon adenocarcinoma.

Gene therapy

Sanati S, Taghavi S, Abnous K, Taghdisi SM, Babaei M, Ramezani M, Alibolandi M.
PMID: 33633357
Gene Ther. 2021 Feb 25; doi: 10.1038/s41434-021-00234-0. Epub 2021 Feb 25.

In this study, we synthesized PLA-PEI micelles which was co-loaded with an anticancer drug, camptothecin (CPT), and survivin-shRNA (sur-shRNA). The hydrophobic CPT was encapsulated in the core of the polymeric micelles while sur-shRNA was adsorbed on the shell of...

Synthesis of block copolymers used in polymersome fabrication: Application in drug delivery.

Journal of controlled release : official journal of the Controlled Release Society

Hasannia M, Aliabadi A, Abnous K, Taghdisi SM, Ramezani M, Alibolandi M.
PMID: 34774891
J Control Release. 2021 Nov 11;341:95-117. doi: 10.1016/j.jconrel.2021.11.010. Epub 2021 Nov 11.

Amphiphilic block copolymers are common materials used for the fabrication of various nanostructures with biomedical applications including nanocapsules, nanospheres, micelles and polymeric vesicles. According to the literature, polymersomes have several advantages compared to other nanostructures used as drug delivery...

Synthesis of block copolymers used in polymersome fabrication: Application in drug delivery.

Journal of controlled release : official journal of the Controlled Release Society

Hasannia M, Aliabadi A, Abnous K, Taghdisi SM, Ramezani M, Alibolandi M.
PMID: 34774891
J Control Release. 2021 Nov 11;341:95-117. doi: 10.1016/j.jconrel.2021.11.010. Epub 2021 Nov 11.

Amphiphilic block copolymers are common materials used for the fabrication of various nanostructures with biomedical applications including nanocapsules, nanospheres, micelles and polymeric vesicles. According to the literature, polymersomes have several advantages compared to other nanostructures used as drug delivery...

Synthesis of block copolymers used in polymersome fabrication: Application in drug delivery.

Journal of controlled release : official journal of the Controlled Release Society

Hasannia M, Aliabadi A, Abnous K, Taghdisi SM, Ramezani M, Alibolandi M.
PMID: 34774891
J Control Release. 2021 Nov 11;341:95-117. doi: 10.1016/j.jconrel.2021.11.010. Epub 2021 Nov 11.

Amphiphilic block copolymers are common materials used for the fabrication of various nanostructures with biomedical applications including nanocapsules, nanospheres, micelles and polymeric vesicles. According to the literature, polymersomes have several advantages compared to other nanostructures used as drug delivery...

Showing 1 to 12 of 44 entries