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Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice.

Nature metabolism

Aliluev A, Tritschler S, Sterr M, Oppenländer L, Hinterdobler J, Greisle T, Irmler M, Beckers J, Sun N, Walch A, Stemmer K, Kindt A, Krumsiek J, Tschöp MH, Luecken MD, Theis FJ, Lickert H, Böttcher A.
PMID: 34552271
Nat Metab. 2021 Sep;3(9):1202-1216. doi: 10.1038/s42255-021-00458-9. Epub 2021 Sep 22.

Excess nutrient uptake and altered hormone secretion in the gut contribute to a systemic energy imbalance, which causes obesity and an increased risk of type 2 diabetes and colorectal cancer. This functional maladaptation is thought to emerge at the...

Author Correction: Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.

Nature cell biology

Böttcher A, Büttner M, Tritschler S, Sterr M, Aliluev A, Oppenländer L, Burtscher I, Sass S, Irmler M, Beckers J, Ziegenhain C, Enard W, Schamberger AC, Verhamme FM, Eickelberg O, Theis FJ, Lickert H.
PMID: 33864032
Nat Cell Biol. 2021 May;23(5):566-576. doi: 10.1038/s41556-021-00667-0.

No abstract available.

Showing 1 to 2 of 2 entries