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Showing 1 to 12 of 95 entries
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Social norms and global environmental challenges: the complex interaction of behaviors, values, and policy

Cultural Transformation in the Geoscience Community AND Program Evaluation

Alston LJ, Barrett S, Ehrlich PR, Kinzig AP.
GSID: buKYduh6ODUJ
AP Kinzig, PR Ehrlich, LJ Alston, K Arrow, S Barrett… - …, 2013 - academic.oup.com

Government policies are needed when people's behaviors fail to deliver the public good. Those policies will be most effective if they can stimulate long-term changes in beliefs and norms, creating and reinforcing the behaviors needed to solidify and extend...

Crude Penicillin Filtrate for Local Treatment.

British medical journal

Alston JM.
PMID: 20785426
Br Med J. 1944 May 13;1(4349):654-6. doi: 10.1136/bmj.1.4349.654.

No abstract available.

Addressing dentistry's "busyness problem".

Journal of the American Dental Association (1939)

Alston PA.
PMID: 26610830
J Am Dent Assoc. 2015 Dec;146(12):871-2. doi: 10.1016/j.adaj.2015.10.017.

No abstract available.

De novo .

Neurology. Genetics

Sommerville EW, Alston CL, Pyle A, He L, Falkous G, Naismith K, Chinnery PF, McFarland R, Taylor RW.
PMID: 28955726
Neurol Genet. 2017 Sep 22;3(5):e187. doi: 10.1212/NXG.0000000000000187. eCollection 2017 Oct.

OBJECTIVE: To determine the genetic etiology of a young woman presenting an early-onset, progressive neurodegenerative disorder with evidence of decreased mitochondrial complex I and IV activities in skeletal muscle suggestive of a mitochondrial disorder.METHODS: A case report including diagnostic...

Preparation of difluoromethylthioethers through difluoromethylation of disulfides using TMS-CF2H.

Chemical communications (Cambridge, England)

Howard JL, Schotten C, Alston ST, Browne DL.
PMID: 27306975
Chem Commun (Camb). 2016 Jun 28;52(54):8448-51. doi: 10.1039/c6cc02693a.

We report an operationally simple, metal-free approach for the late-stage introduction of the important lipophilic hydrogen-bond donor motif, SCF2H. This reaction converts diaryl- and dialkyl-disulfides into the corresponding aryl/alkyl-SCF2H through the nucleophilic transfer of a difluoromethyl group with good...

Identification of Residues in Lassa Virus Glycoprotein Subunit 2 That Are Critical for Protein Function.

Pathogens (Basel, Switzerland)

Willard KA, Alston JT, Acciani M, Brindley MA.
PMID: 30587764
Pathogens. 2018 Dec 26;8(1). doi: 10.3390/pathogens8010001.

Lassa virus (LASV) is an Old World arenavirus, endemic to West Africa, capable of causing hemorrhagic fever. Currently, there are no approved vaccines or effective antivirals for LASV. However, thorough understanding of the LASV glycoprotein and entry into host...

Coupled-Sturmian and perturbative treatments of electron transfer and ionization in high-energy p-He+ collisions.

Physical review. A, Atomic, molecular, and optical physics

Alston SG, Winter TG.
PMID: 9907140
Phys Rev A. 1992 Feb 01;45(3):1562-1568. doi: 10.1103/physreva.45.1562.

No abstract available.

Cardiothoracic Anesthesia and Critical Care in the United Kingdom (UK) Part 1: Some Insights Into the History and Development.

Journal of cardiothoracic and vascular anesthesia

Royston D, Alston RP.
PMID: 33726943
J Cardiothorac Vasc Anesth. 2021 Dec;35(12):3746-3759. doi: 10.1053/j.jvca.2021.02.030. Epub 2021 Feb 13.

This review is intended to highlight some of the historic events that contributed to the development of thoracic and cardiac anesthesia and surgery in Great Britain and Northern Ireland (UK). The aim of this first of two parts is...

Natural History of Leigh Syndrome: A Study of Disease Burden and Progression.

Annals of neurology

Lim AZ, Ng YS, Blain A, Jiminez-Moreno C, Alston CL, Nesbitt V, Simmons L, Santra S, Wassmer E, Blakely EL, Turnbull DM, Taylor RW, Gorman GS, McFarland R.
PMID: 34716721
Ann Neurol. 2021 Oct 30; doi: 10.1002/ana.26260. Epub 2021 Oct 30.

OBJECTIVE: This observational cohort study aims to quantify disease burden over time, establish disease progression rates, and identify factors that may determine the disease course of Leigh syndrome.METHODS: Seventy-two Leigh syndrome children who completed the Newcastle Paediatric Mitochondrial Disease...

The genetics of mitochondrial disease: dissecting mitochondrial pathology using multi-omic pipelines.

The Journal of pathology

Alston CL, Stenton SL, Hudson G, Prokisch H, Taylor RW.
PMID: 33586140
J Pathol. 2021 Jul;254(4):430-442. doi: 10.1002/path.5641. Epub 2021 Mar 26.

Mitochondria play essential roles in numerous metabolic pathways including the synthesis of adenosine triphosphate through oxidative phosphorylation. Clinically, mitochondrial diseases occur when there is mitochondrial dysfunction - manifesting at any age and affecting any organ system; tissues with high...

Accelerated robotic discovery of type II porous liquids.

Chemical science

Kearsey RJ, Alston BM, Briggs ME, Greenaway RL, Cooper AI.
PMID: 32110304
Chem Sci. 2019 Aug 28;10(41):9454-9465. doi: 10.1039/c9sc03316e. eCollection 2019 Nov 07.

Porous liquids are an emerging class of materials and to date little is known about how to best design their properties. For example, bulky solvents are required that are size-excluded from the pores in the liquid, along with high...

High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis.

Nature communications

Greenaway RL, Santolini V, Bennison MJ, Alston BM, Pugh CJ, Little MA, Miklitz M, Eden-Rump EGB, Clowes R, Shakil A, Cuthbertson HJ, Armstrong H, Briggs ME, Jelfs KE, Cooper AI.
PMID: 30030426
Nat Commun. 2018 Jul 20;9(1):2849. doi: 10.1038/s41467-018-05271-9.

Supramolecular synthesis is a powerful strategy for assembling complex molecules, but to do this by targeted design is challenging. This is because multicomponent assembly reactions have the potential to form a wide variety of products. High-throughput screening can explore...

Showing 1 to 12 of 95 entries