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Showing 1 to 12 of 32 entries
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Feasibility of using microencapsulated phase change materials as filler for improving low temperature performance of rubber sealing materials.

Soft matter

Tiwari A, Shubin SN, Alcock B, Freidin AB, Thorkildsen B, Echtermeyer AT.
PMID: 28994839
Soft Matter. 2017 Nov 01;13(42):7760-7770. doi: 10.1039/c7sm01623a.

The feasibility of a novel composite rubber sealing material to improve sealing under transient cooling (in a so-called blowdown scenario) is investigated here. A composite of hydrogenated nitrile butadiene rubber (HNBR) filled with Micro Encapsulated Phase Change Materials (MEPCM)...

Psychosocial factors associated with repeat diabetic ketoacidosis in people living with type 1 diabetes: A systematic review.

Diabetic medicine : a journal of the British Diabetic Association

Allcock B, Stewart R, Jackson M.
PMID: 34324739
Diabet Med. 2021 Jul 29;e14663. doi: 10.1111/dme.14663. Epub 2021 Jul 29.

AIM: To systematically review the literature concerning the psychosocial factors associated with repeat diabetic ketoacidosis for people living with type 1 diabetes.METHODS: PsycInfo, Web of Science, CINAHL, PubMed and ASSIA were searched according to a registered study protocol (PROSPERO...

Bone marrow derived stromal cells from myelodysplastic syndromes are altered but not clonally mutated in vivo.

Nature communications

Jann JC, Mossner M, Riabov V, Altrock E, Schmitt N, Flach J, Xu Q, Nowak V, Obländer J, Palme I, Weimer N, Streuer A, Jawhar A, Darwich A, Jawhar M, Metzgeroth G, Nolte F, Hofmann WK, Nowak D.
PMID: 34697318
Nat Commun. 2021 Oct 25;12(1):6170. doi: 10.1038/s41467-021-26424-3.

The bone marrow (BM) stroma in myeloid neoplasms is altered and it is hypothesized that this cell compartment may also harbor clonal somatically acquired mutations. By exome sequencing of in vitro expanded mesenchymal stromal cells (MSCs) from n =...

Psychosocial factors associated with repeat diabetic ketoacidosis in people living with type 1 diabetes: A systematic review.

Diabetic medicine : a journal of the British Diabetic Association

Allcock B, Stewart R, Jackson M.
PMID: 34324739
Diabet Med. 2022 Jan;39(1):e14663. doi: 10.1111/dme.14663. Epub 2021 Aug 13.

AIM: To systematically review the literature concerning the psychosocial factors associated with repeat diabetic ketoacidosis for people living with type 1 diabetes.METHODS: PsycInfo, Web of Science, CINAHL, PubMed and ASSIA were searched according to a registered study protocol (PROSPERO...

Quantification of T- and B-cell immune receptor distribution diversity characterizes immune cell infiltration and lymphocyte heterogeneity in clear cell renal cell carcinoma.

Cancer research

Ferrall-Fairbanks MC, Chakiryan N, Chobrutskiy BI, Kim Y, Teer JK, Berglund A, Mulé JJ, Fournier M, Siegel EM, Dhillon J, Falasiri SSA, Arturo JF, Katende EN, Blanck G, Manley BJ, Altrock PM.
PMID: 35031572
Cancer Res. 2022 Jan 14; doi: 10.1158/0008-5472.CAN-21-1747. Epub 2022 Jan 14.

Immune-modulating systemic therapies are often used to treat advanced cancer such as metastatic clear cell renal cell carcinoma (ccRCC). Used alone, sequence-based biomarkers neither accurately capture patient dynamics nor the tumor immune microenvironment. To better understand the tumor ecology...

Imaging spectroscopy of solar radio burst fine structures.

Nature communications

Kontar EP, Yu S, Kuznetsov AA, Emslie AG, Alcock B, Jeffrey NLS, Melnik VN, Bian NH, Subramanian P.
PMID: 29142220
Nat Commun. 2017 Nov 15;8(1):1515. doi: 10.1038/s41467-017-01307-8.

Solar radio observations provide a unique diagnostic of the outer solar atmosphere. However, the inhomogeneous turbulent corona strongly affects the propagation of the emitted radio waves, so decoupling the intrinsic properties of the emitting source from the effects of...

EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer.

PLoS biology

Rossnagl S, Altrock E, Sens C, Kraft S, Rau K, Milsom MD, Giese T, Samstag Y, Nakchbandi IA.
PMID: 27653627
PLoS Biol. 2016 Sep 21;14(9):e1002562. doi: 10.1371/journal.pbio.1002562. eCollection 2016 Sep.

Osteoblasts lining the inner surface of bone support hematopoietic stem cell differentiation by virtue of proximity to the bone marrow. The osteoblasts also modify their own differentiation by producing various isoforms of fibronectin (FN). Despite evidence for immune regulation...

Barriers to radiotherapy access at the University College Hospital in Ibadan, Nigeria.

Clinical and translational radiation oncology

Anakwenze CP, Ntekim A, Trock B, Uwadiae IB, Page BR.
PMID: 29594210
Clin Transl Radiat Oncol. 2017 Jun 21;5:1-5. doi: 10.1016/j.ctro.2017.05.003. eCollection 2017 Aug.

INTRODUCTION: Nigeria has the biggest gap between radiotherapy availability and need, with one machine per 19.4 million people, compared to one machine per 250,000 people in high-income countries. This study aims to identify its patient-level barriers to radiotherapy access.MATERIAL...

Re: Simulation analysis for tumor radiotherapy based on three-component mathematical models.

Journal of applied clinical medical physics

Ferrall-Fairbanks MC, Glazar DJ, Brady RJ, Kimmel GJ, Zahid MU, Altrock PM, Enderling H.
PMID: 31145529
J Appl Clin Med Phys. 2019 Jul;20(7):204-205. doi: 10.1002/acm2.12608. Epub 2019 May 30.

No abstract available.

Comparison of Characteristics, Follow-up and Outcomes of Active Surveillance for Prostate Cancer According to Ethnicity in the GAP3 Global Consortium Database.

European urology open science

Beckmann K, Santaolalla A, Helleman J, Carroll P, Ha Chung B, Shiong Lee L, Perry A, Rubio-Briones J, Sugimoto M, Trock B, Valdagni R, Dasgupta P, Van Hemelrijck M, Elhage O.
PMID: 34934967
Eur Urol Open Sci. 2021 Nov 01;34:47-54. doi: 10.1016/j.euros.2021.09.012. eCollection 2021 Dec.

BACKGROUND: Studies of active surveillance (AS) for prostate cancer (PCa) have focussed predominantly on Caucasian populations. Little is known about the experience of Asian men, while suitability for men of African descent has been questioned.OBJECTIVE: To compare baseline characteristics,...

Tipping cancer cells over the edge: the context-dependent cost of high ploidy.

Cancer research

Andor N, Altrock PM, Jain N, Gomes AP.
PMID: 34785577
Cancer Res. 2021 Nov 16; doi: 10.1158/0008-5472.CAN-21-2794. Epub 2021 Nov 16.

Tetraploidy is an aneuploidy-permissive condition that can fuel tumorgenesis. The tip-over hypothesis of cytotoxic therapy-sensitivity proposes that therapy is effective if it pushes a cell's aneuploidy above a viable tipping point. But elevated aneuploidy alone may not account for...

Humanized three-dimensional scaffold xenotransplantation models for myelodysplastic syndromes.

Experimental hematology

Altrock E, Sens-Albert C, Jann JC, Flach J, Riabov V, Schmitt N, Xu Q, Mehralivand A, Hecht A, Steiner L, Streuer A, Nowak V, Obländer J, Weimer N, Palme I, Jawhar A, Weis CA, Weyer V, Nolte F, Jawhar M, Metzgeroth G, Marx A, Groden C, Hofmann WK, Nowak D.
PMID: 34952140
Exp Hematol. 2021 Dec 22; doi: 10.1016/j.exphem.2021.12.395. Epub 2021 Dec 22.

Patient-derived xenograft (PDX) models have emerged as versatile preclinical platforms for investigation of functional pathomechanisms in myelodysplastic syndromes (MDS) and other myeloid neoplasms. However, despite increasingly improved methodology, engraftment efficiencies frequently remain low. Humanized three-dimensional scaffold models (ossicle xenotransplantation...

Showing 1 to 12 of 32 entries