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Idebenone increases mitochondrial complex I activity in fibroblasts from LHON patients while producing contradictory effects on respiration.

BMC research notes

Angebault C, Gueguen N, Desquiret-Dumas V, Chevrollier A, Guillet V, Verny C, Cassereau J, Ferre M, Milea D, Amati-Bonneau P, Bonneau D, Procaccio V, Reynier P, Loiseau D.
PMID: 22192149
BMC Res Notes. 2011 Dec 22;4:557. doi: 10.1186/1756-0500-4-557.

BACKGROUND: Leber's hereditary optic neuropathy (LHON) is caused by mutations in the complex I subunits of the respiratory chain. Although patients have been treated with idebenone since 1992, the efficacy of the drug is still a matter of debate.METHODS:...

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Angebault C, Gueguen N, Desquiret-Dumas V, et al. Idebenone increases mitochondrial complex I activity in fibroblasts from LHON patients while producing contradictory effects on respiration. BMC Res Notes. 2011;4:557doi: 10.1186/1756-0500-4-557.
Angebault, C., Gueguen, N., Desquiret-Dumas, V., Chevrollier, A., Guillet, V., Verny, C., Cassereau, J., Ferre, M., Milea, D., Amati-Bonneau, P., Bonneau, D., Procaccio, V., Reynier, P., & Loiseau, D. (2011). Idebenone increases mitochondrial complex I activity in fibroblasts from LHON patients while producing contradictory effects on respiration. BMC research notes, 4557. https://doi.org/10.1186/1756-0500-4-557
Angebault, Claire, et al. "Idebenone increases mitochondrial complex I activity in fibroblasts from LHON patients while producing contradictory effects on respiration." BMC research notes vol. 4 (2011): 557. doi: https://doi.org/10.1186/1756-0500-4-557
Angebault C, Gueguen N, Desquiret-Dumas V, Chevrollier A, Guillet V, Verny C, Cassereau J, Ferre M, Milea D, Amati-Bonneau P, Bonneau D, Procaccio V, Reynier P, Loiseau D. Idebenone increases mitochondrial complex I activity in fibroblasts from LHON patients while producing contradictory effects on respiration. BMC Res Notes. 2011 Dec 22;4:557. doi: 10.1186/1756-0500-4-557. PMID: 22192149; PMCID: PMC3285568.
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Azole Resistance in Clinical and Environmental .

Journal of fungi (Basel, Switzerland)

Monpierre L, Desbois-Nogard N, Valsecchi I, Bajal M, Angebault C, Miossec C, Botterel F, Dannaoui É.
PMID: 33946598
J Fungi (Basel). 2021 Apr 30;7(5). doi: 10.3390/jof7050355.

The emergence of azole resistant

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Monpierre L, Desbois-Nogard N, Valsecchi I, et al. Azole Resistance in Clinical and Environmental . J Fungi (Basel). 2021;7(5)doi: 10.3390/jof7050355.
Monpierre, L., Desbois-Nogard, N., Valsecchi, I., Bajal, M., Angebault, C., Miossec, C., Botterel, F., & Dannaoui, �. �. (2021). Azole Resistance in Clinical and Environmental . Journal of fungi (Basel, Switzerland), 7(5), . https://doi.org/10.3390/jof7050355
Monpierre, Lorra, et al. "Azole Resistance in Clinical and Environmental ." Journal of fungi (Basel, Switzerland) vol. 7,5 (2021). doi: https://doi.org/10.3390/jof7050355
Monpierre L, Desbois-Nogard N, Valsecchi I, Bajal M, Angebault C, Miossec C, Botterel F, Dannaoui É. Azole Resistance in Clinical and Environmental . J Fungi (Basel). 2021 Apr 30;7(5). doi: 10.3390/jof7050355. PMID: 33946598; PMCID: PMC8147181.
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Analysis of Microbiota and Mycobiota in Fungal Ball Rhinosinusitis: Specific Interaction between .

Journal of fungi (Basel, Switzerland)

Dellière S, Dannaoui E, Fieux M, Bonfils P, Gricourt G, Demontant V, Podglajen I, Woerther PL, Angebault C, Botterel F.
PMID: 34356929
J Fungi (Basel). 2021 Jul 10;7(7). doi: 10.3390/jof7070550.

Fungal ball (FB) rhinosinusitis (RS) is the main type of non-invasive fungal RS. Despite positive direct examination (DE) of biopsies, culture remains negative in more than 60% of cases. The aim of the study was to evaluate the performance/efficacy...

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Dellière S, Dannaoui E, Fieux M, et al. Analysis of Microbiota and Mycobiota in Fungal Ball Rhinosinusitis: Specific Interaction between . J Fungi (Basel). 2021;7(7)doi: 10.3390/jof7070550.
Dellière, S., Dannaoui, E., Fieux, M., Bonfils, P., Gricourt, G., Demontant, V., Podglajen, I., Woerther, P. L., Angebault, C., & Botterel, F. (2021). Analysis of Microbiota and Mycobiota in Fungal Ball Rhinosinusitis: Specific Interaction between . Journal of fungi (Basel, Switzerland), 7(7), . https://doi.org/10.3390/jof7070550
Dellière, Sarah, et al. "Analysis of Microbiota and Mycobiota in Fungal Ball Rhinosinusitis: Specific Interaction between ." Journal of fungi (Basel, Switzerland) vol. 7,7 (2021). doi: https://doi.org/10.3390/jof7070550
Dellière S, Dannaoui E, Fieux M, Bonfils P, Gricourt G, Demontant V, Podglajen I, Woerther PL, Angebault C, Botterel F. Analysis of Microbiota and Mycobiota in Fungal Ball Rhinosinusitis: Specific Interaction between . J Fungi (Basel). 2021 Jul 10;7(7). doi: 10.3390/jof7070550. PMID: 34356929; PMCID: PMC8305266.
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Mucor irregularis-associated cutaneous mucormycosis: Case report and review.

Medical mycology case reports

Rammaert B, Angebault C, Scemla A, Fraitag S, Lerolle N, Lecuit M, Bougnoux ME, Lortholary O.
PMID: 25379401
Med Mycol Case Rep. 2014 Jul 24;6:62-5. doi: 10.1016/j.mmcr.2014.07.005. eCollection 2014 Oct.

Solid organ transplant recipients are at risk for invasive fungal diseases, and are also exposed to healthcare-associated mucormycosis. Mainly causing localized cutaneous mucormycosis, Mucor irregularis infection is reported for the first time in a kidney-transplant recipient. A healthcare-associated origin...

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Rammaert B, Angebault C, Scemla A, et al. Mucor irregularis-associated cutaneous mucormycosis: Case report and review. Med Mycol Case Rep. 2014;6:62-5doi: 10.1016/j.mmcr.2014.07.005.
Rammaert, B., Angebault, C., Scemla, A., Fraitag, S., Lerolle, N., Lecuit, M., Bougnoux, M. E., & Lortholary, O. (2014). Mucor irregularis-associated cutaneous mucormycosis: Case report and review. Medical mycology case reports, 662-5. https://doi.org/10.1016/j.mmcr.2014.07.005
Rammaert, Blandine, et al. "Mucor irregularis-associated cutaneous mucormycosis: Case report and review." Medical mycology case reports vol. 6 (2014): 62-5. doi: https://doi.org/10.1016/j.mmcr.2014.07.005
Rammaert B, Angebault C, Scemla A, Fraitag S, Lerolle N, Lecuit M, Bougnoux ME, Lortholary O. Mucor irregularis-associated cutaneous mucormycosis: Case report and review. Med Mycol Case Rep. 2014 Jul 24;6:62-5. doi: 10.1016/j.mmcr.2014.07.005. eCollection 2014 Oct. PMID: 25379401; PMCID: PMC4216332.
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Loss of function of .

Cell death discovery

Buret L, Rebillard G, Brun E, Angebault C, Pequignot M, Lenoir M, Do-Cruzeiro M, Tournier E, Cornille K, Saleur A, Gueguen N, Reynier P, Amati-Bonneau P, Barakat A, Blanchet C, Chinnery P, Yu-Wai-Man P, Kaplan J, Roux AF, Van Camp G, Wissinger B, Boespflug-Tanguy O, Giraudet F, Puel JL, Lenaers G, Hamel C, Delprat B, Delettre C.
PMID: 27275396
Cell Death Discov. 2016 Mar 07;2:16017. doi: 10.1038/cddiscovery.2016.17.

In vertebrates, 14-3-3 proteins form a family of seven highly conserved isoforms with chaperone activity, which bind phosphorylated substrates mostly involved in regulatory and checkpoint pathways. 14-3-3 proteins are the most abundant protein in the brain and are abundantly...

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Buret L, Rebillard G, Brun E, et al. Loss of function of . Cell Death Discov. 2016;2:16017doi: 10.1038/cddiscovery.2016.17.
Buret, L., Rebillard, G., Brun, E., Angebault, C., Pequignot, M., Lenoir, M., Do-Cruzeiro, M., Tournier, E., Cornille, K., Saleur, A., Gueguen, N., Reynier, P., Amati-Bonneau, P., Barakat, A., Blanchet, C., Chinnery, P., Yu-Wai-Man, P., Kaplan, J., Roux, A. F., Van Camp, G., Wissinger, B., Boespflug-Tanguy, O., Giraudet, F., Puel, J. L., Lenaers, G., Hamel, C., Delprat, B., & Delettre, C. (2016). Loss of function of . Cell death discovery, 216017. https://doi.org/10.1038/cddiscovery.2016.17
Buret, L, et al. "Loss of function of ." Cell death discovery vol. 2 (2016): 16017. doi: https://doi.org/10.1038/cddiscovery.2016.17
Buret L, Rebillard G, Brun E, Angebault C, Pequignot M, Lenoir M, Do-Cruzeiro M, Tournier E, Cornille K, Saleur A, Gueguen N, Reynier P, Amati-Bonneau P, Barakat A, Blanchet C, Chinnery P, Yu-Wai-Man P, Kaplan J, Roux AF, Van Camp G, Wissinger B, Boespflug-Tanguy O, Giraudet F, Puel JL, Lenaers G, Hamel C, Delprat B, Delettre C. Loss of function of . Cell Death Discov. 2016 Mar 07;2:16017. doi: 10.1038/cddiscovery.2016.17. PMID: 27275396; PMCID: PMC4893315.
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Increased steroidogenesis promotes early-onset and severe vision loss in females with OPA1 dominant optic atrophy.

Human molecular genetics

Sarzi E, Seveno M, Angebault C, Milea D, Rönnbäck C, Quilès M, Adrian M, Grenier J, Caignard A, Lacroux A, Lavergne C, Reynier P, Larsen M, Hamel CP, Delettre C, Lenaers G, Müller A.
PMID: 29045675
Hum Mol Genet. 2017 Dec 01;26(23):4764. doi: 10.1093/hmg/ddx376.

No abstract available.

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Sarzi E, Seveno M, Angebault C, et al. Increased steroidogenesis promotes early-onset and severe vision loss in females with OPA1 dominant optic atrophy. Hum Mol Genet. 2017;26(23):4764doi: 10.1093/hmg/ddx376.
Sarzi, E., Seveno, M., Angebault, C., Milea, D., Rönnbäck, C., Quilès, M., Adrian, M., Grenier, J., Caignard, A., Lacroux, A., Lavergne, C., Reynier, P., Larsen, M., Hamel, C. P., Delettre, C., Lenaers, G., & Müller, A. (2017). Increased steroidogenesis promotes early-onset and severe vision loss in females with OPA1 dominant optic atrophy. Human molecular genetics, 26(23), 4764. https://doi.org/10.1093/hmg/ddx376
Sarzi, Emmanuelle, et al. "Increased steroidogenesis promotes early-onset and severe vision loss in females with OPA1 dominant optic atrophy." Human molecular genetics vol. 26,23 (2017): 4764. doi: https://doi.org/10.1093/hmg/ddx376
Sarzi E, Seveno M, Angebault C, Milea D, Rönnbäck C, Quilès M, Adrian M, Grenier J, Caignard A, Lacroux A, Lavergne C, Reynier P, Larsen M, Hamel CP, Delettre C, Lenaers G, Müller A. Increased steroidogenesis promotes early-onset and severe vision loss in females with OPA1 dominant optic atrophy. Hum Mol Genet. 2017 Dec 01;26(23):4764. doi: 10.1093/hmg/ddx376. PMID: 29045675.
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Concomitant Presence of .

Frontiers in microbiology

Dellière S, Angebault C, Fihman V, Foulet F, Lepeule R, Maitre B, Schlemmer F, Botterel F.
PMID: 31998267
Front Microbiol. 2020 Jan 10;10:2980. doi: 10.3389/fmicb.2019.02980. eCollection 2019.

METHODS: A retrospective monocentric study was conducted from January 2011 to December 2017, including all in-patients from whom positive cultures of RESULTS: Overall, 140 patients had ≥1 respiratory samples positive for CONCLUSION: In this first study focusing on co-isolation...

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Dellière S, Angebault C, Fihman V, et al. Concomitant Presence of . Front Microbiol. 2020;10:2980doi: 10.3389/fmicb.2019.02980.
Dellière, S., Angebault, C., Fihman, V., Foulet, F., Lepeule, R., Maitre, B., Schlemmer, F., & Botterel, F. (2019). Concomitant Presence of . Frontiers in microbiology, 102980. https://doi.org/10.3389/fmicb.2019.02980
Dellière, Sarah, et al. "Concomitant Presence of ." Frontiers in microbiology vol. 10 (2019): 2980. doi: https://doi.org/10.3389/fmicb.2019.02980
Dellière S, Angebault C, Fihman V, Foulet F, Lepeule R, Maitre B, Schlemmer F, Botterel F. Concomitant Presence of . Front Microbiol. 2020 Jan 10;10:2980. doi: 10.3389/fmicb.2019.02980. eCollection 2019. PMID: 31998267; PMCID: PMC6967598.
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Metformin Reverses the Enhanced Myocardial SR/ER-Mitochondria Interaction and Impaired Complex I-Driven Respiration in Dystrophin-Deficient Mice.

Frontiers in cell and developmental biology

Angebault C, Panel M, Lacôte M, Rieusset J, Lacampagne A, Fauconnier J.
PMID: 33569379
Front Cell Dev Biol. 2021 Jan 25;8:609493. doi: 10.3389/fcell.2020.609493. eCollection 2020.

Besides skeletal muscle dysfunction, Duchenne muscular dystrophy (DMD) exhibits a progressive cardiomyopathy characterized by an impaired calcium (Ca

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Angebault C, Panel M, Lacôte M, et al. Metformin Reverses the Enhanced Myocardial SR/ER-Mitochondria Interaction and Impaired Complex I-Driven Respiration in Dystrophin-Deficient Mice. Front Cell Dev Biol. 2021;8:609493doi: 10.3389/fcell.2020.609493.
Angebault, C., Panel, M., Lacôte, M., Rieusset, J., Lacampagne, A., & Fauconnier, J. (2020). Metformin Reverses the Enhanced Myocardial SR/ER-Mitochondria Interaction and Impaired Complex I-Driven Respiration in Dystrophin-Deficient Mice. Frontiers in cell and developmental biology, 8609493. https://doi.org/10.3389/fcell.2020.609493
Angebault, Claire, et al. "Metformin Reverses the Enhanced Myocardial SR/ER-Mitochondria Interaction and Impaired Complex I-Driven Respiration in Dystrophin-Deficient Mice." Frontiers in cell and developmental biology vol. 8 (2020): 609493. doi: https://doi.org/10.3389/fcell.2020.609493
Angebault C, Panel M, Lacôte M, Rieusset J, Lacampagne A, Fauconnier J. Metformin Reverses the Enhanced Myocardial SR/ER-Mitochondria Interaction and Impaired Complex I-Driven Respiration in Dystrophin-Deficient Mice. Front Cell Dev Biol. 2021 Jan 25;8:609493. doi: 10.3389/fcell.2020.609493. eCollection 2020. PMID: 33569379; PMCID: PMC7868535.
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Molecular Demonstration of a Pneumocystis Outbreak in Stem Cell Transplant Patients: Evidence for Transmission in the Daycare Center.

Frontiers in microbiology

Robin C, Alanio A, Gits-Muselli M, la Martire G, Schlemmer F, Botterel F, Angebault C, Leclerc M, Beckerich F, Redjoul R, Pautas C, Toma A, Maury S, Bretagne S, Cordonnier C.
PMID: 28484441
Front Microbiol. 2017 Apr 24;8:700. doi: 10.3389/fmicb.2017.00700. eCollection 2017.

No abstract available.

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Robin C, Alanio A, Gits-Muselli M, et al. Molecular Demonstration of a Pneumocystis Outbreak in Stem Cell Transplant Patients: Evidence for Transmission in the Daycare Center. Front Microbiol. 2017;8:700doi: 10.3389/fmicb.2017.00700.
Robin, C., Alanio, A., Gits-Muselli, M., la Martire, G., Schlemmer, F., Botterel, F., Angebault, C., Leclerc, M., Beckerich, F., Redjoul, R., Pautas, C., Toma, A., Maury, S., Bretagne, S., & Cordonnier, C. (2017). Molecular Demonstration of a Pneumocystis Outbreak in Stem Cell Transplant Patients: Evidence for Transmission in the Daycare Center. Frontiers in microbiology, 8700. https://doi.org/10.3389/fmicb.2017.00700
Robin, Christine, et al. "Molecular Demonstration of a Pneumocystis Outbreak in Stem Cell Transplant Patients: Evidence for Transmission in the Daycare Center." Frontiers in microbiology vol. 8 (2017): 700. doi: https://doi.org/10.3389/fmicb.2017.00700
Robin C, Alanio A, Gits-Muselli M, la Martire G, Schlemmer F, Botterel F, Angebault C, Leclerc M, Beckerich F, Redjoul R, Pautas C, Toma A, Maury S, Bretagne S, Cordonnier C. Molecular Demonstration of a Pneumocystis Outbreak in Stem Cell Transplant Patients: Evidence for Transmission in the Daycare Center. Front Microbiol. 2017 Apr 24;8:700. doi: 10.3389/fmicb.2017.00700. eCollection 2017. PMID: 28484441; PMCID: PMC5401873.
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Prospective Evaluation of Serum β-Glucan Testing in Patients With Probable or Proven Fungal Diseases.

Open forum infectious diseases

Angebault C, Lanternier F, Dalle F, Schrimpf C, Roupie AL, Dupuis A, Agathine A, Scemla A, Paubelle E, Caillot D, Neven B, Frange P, Suarez F, d'Enfert C, Lortholary O, Bougnoux ME.
PMID: 27419189
Open Forum Infect Dis. 2016 Jun 16;3(3):ofw128. doi: 10.1093/ofid/ofw128. eCollection 2016 Sep.

Background.  Early diagnosis and treatment are crucial in invasive fungal diseases (IFD). Serum (1-3)-β-d-glucan (BG) is believed to be an early IFD marker, but its diagnostic performance has been ambiguous, with insufficient data regarding sensitivity at the time of...

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Angebault C, Lanternier F, Dalle F, et al. Prospective Evaluation of Serum β-Glucan Testing in Patients With Probable or Proven Fungal Diseases. Open Forum Infect Dis. 2016;3(3):ofw128doi: 10.1093/ofid/ofw128.
Angebault, C., Lanternier, F., Dalle, F., Schrimpf, C., Roupie, A. L., Dupuis, A., Agathine, A., Scemla, A., Paubelle, E., Caillot, D., Neven, B., Frange, P., Suarez, F., d'Enfert, C., Lortholary, O., & Bougnoux, M. E. (2016). Prospective Evaluation of Serum β-Glucan Testing in Patients With Probable or Proven Fungal Diseases. Open forum infectious diseases, 3(3), ofw128. https://doi.org/10.1093/ofid/ofw128
Angebault, Cécile, et al. "Prospective Evaluation of Serum β-Glucan Testing in Patients With Probable or Proven Fungal Diseases." Open forum infectious diseases vol. 3,3 (2016): ofw128. doi: https://doi.org/10.1093/ofid/ofw128
Angebault C, Lanternier F, Dalle F, Schrimpf C, Roupie AL, Dupuis A, Agathine A, Scemla A, Paubelle E, Caillot D, Neven B, Frange P, Suarez F, d'Enfert C, Lortholary O, Bougnoux ME. Prospective Evaluation of Serum β-Glucan Testing in Patients With Probable or Proven Fungal Diseases. Open Forum Infect Dis. 2016 Jun 16;3(3):ofw128. doi: 10.1093/ofid/ofw128. eCollection 2016 Sep. PMID: 27419189; PMCID: PMC4942764.
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The Potential Role of Clinical Metagenomics in Infectious Diseases: Therapeutic Perspectives.

Drugs

d'Humières C, Salmona M, Dellière S, Leo S, Rodriguez C, Angebault C, Alanio A, Fourati S, Lazarevic V, Woerther PL, Schrenzel J, Ruppé E.
PMID: 34328626
Drugs. 2021 Sep;81(13):1453-1466. doi: 10.1007/s40265-021-01572-4. Epub 2021 Jul 30.

Clinical metagenomics (CMg) is the process of sequencing nucleic acid of clinical samples to obtain clinically relevant information such as the identification of microorganisms and their susceptibility to antimicrobials. Over the last decades, sequencing and bioinformatic solutions supporting CMg...

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d'Humières C, Salmona M, Dellière S, et al. The Potential Role of Clinical Metagenomics in Infectious Diseases: Therapeutic Perspectives. Drugs. 2021;81(13):1453-1466doi: 10.1007/s40265-021-01572-4.
d'Humières, C., Salmona, M., Dellière, S., Leo, S., Rodriguez, C., Angebault, C., Alanio, A., Fourati, S., Lazarevic, V., Woerther, P. L., Schrenzel, J., & Ruppé, E. (2021). The Potential Role of Clinical Metagenomics in Infectious Diseases: Therapeutic Perspectives. Drugs, 81(13), 1453-1466. https://doi.org/10.1007/s40265-021-01572-4
d'Humières, Camille, et al. "The Potential Role of Clinical Metagenomics in Infectious Diseases: Therapeutic Perspectives." Drugs vol. 81,13 (2021): 1453-1466. doi: https://doi.org/10.1007/s40265-021-01572-4
d'Humières C, Salmona M, Dellière S, Leo S, Rodriguez C, Angebault C, Alanio A, Fourati S, Lazarevic V, Woerther PL, Schrenzel J, Ruppé E. The Potential Role of Clinical Metagenomics in Infectious Diseases: Therapeutic Perspectives. Drugs. 2021 Sep;81(13):1453-1466. doi: 10.1007/s40265-021-01572-4. Epub 2021 Jul 30. PMID: 34328626; PMCID: PMC8323086.
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