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Protection against Radiotherapy-Induced Toxicity.

Antioxidants (Basel, Switzerland)

Hall S, Rudrawar S, Zunk M, Bernaitis N, Arora D, McDermott CM, Anoopkumar-Dukie S.
PMID: 27399787
Antioxidants (Basel). 2016 Jul 05;5(3). doi: 10.3390/antiox5030022.

Radiation therapy is a highly utilized therapy in the treatment of malignancies with up to 60% of cancer patients receiving radiation therapy as a part of their treatment regimen. Radiation therapy does, however, cause a wide range of adverse...

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Hall S, Rudrawar S, Zunk M, et al. Protection against Radiotherapy-Induced Toxicity. Antioxidants (Basel). 2016;5(3)doi: 10.3390/antiox5030022.
Hall, S., Rudrawar, S., Zunk, M., Bernaitis, N., Arora, D., McDermott, C. M., & Anoopkumar-Dukie, S. (2016). Protection against Radiotherapy-Induced Toxicity. Antioxidants (Basel, Switzerland), 5(3), . https://doi.org/10.3390/antiox5030022
Hall, Susan, et al. "Protection against Radiotherapy-Induced Toxicity." Antioxidants (Basel, Switzerland) vol. 5,3 (2016). doi: https://doi.org/10.3390/antiox5030022
Hall S, Rudrawar S, Zunk M, Bernaitis N, Arora D, McDermott CM, Anoopkumar-Dukie S. Protection against Radiotherapy-Induced Toxicity. Antioxidants (Basel). 2016 Jul 05;5(3). doi: 10.3390/antiox5030022. PMID: 27399787; PMCID: PMC5039571.
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Correction: Housefly (Musca domestica) larvae powder, preventing oxidative stress injury via regulation of UCP4 and CyclinD1 and modulation of JNK and P38 signaling in APP/PS1 mice.

Food & function

He Y, Yang X, Jiao M, Anoopkumar-Dukie S, Zeng Y, Mei H.
PMID: 31549114
Food Funct. 2019 Oct 16;10(10):6945. doi: 10.1039/c9fo90050k.

Correction for 'Housefly (Musca domestica) larvae powder, preventing oxidative stress injury via regulation of UCP4 and CyclinD1 and modulation of JNK and P38 signaling in APP/PS1 mice' by Yinru He et al., Food Funct., 2019, 10, 235-243.

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He Y, Yang X, Jiao M, et al. Correction: Housefly (Musca domestica) larvae powder, preventing oxidative stress injury via regulation of UCP4 and CyclinD1 and modulation of JNK and P38 signaling in APP/PS1 mice. Food Funct. 2019;10(10):6945doi: 10.1039/c9fo90050k.
He, Y., Yang, X., Jiao, M., Anoopkumar-Dukie, S., Zeng, Y., & Mei, H. (2019). Correction: Housefly (Musca domestica) larvae powder, preventing oxidative stress injury via regulation of UCP4 and CyclinD1 and modulation of JNK and P38 signaling in APP/PS1 mice. Food & function, 10(10), 6945. https://doi.org/10.1039/c9fo90050k
He, Yinru, et al. "Correction: Housefly (Musca domestica) larvae powder, preventing oxidative stress injury via regulation of UCP4 and CyclinD1 and modulation of JNK and P38 signaling in APP/PS1 mice." Food & function vol. 10,10 (2019): 6945. doi: https://doi.org/10.1039/c9fo90050k
He Y, Yang X, Jiao M, Anoopkumar-Dukie S, Zeng Y, Mei H. Correction: Housefly (Musca domestica) larvae powder, preventing oxidative stress injury via regulation of UCP4 and CyclinD1 and modulation of JNK and P38 signaling in APP/PS1 mice. Food Funct. 2019 Oct 16;10(10):6945. doi: 10.1039/c9fo90050k. PMID: 31549114.
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An education on pharmacologically active complementary and alternative medicine and its effects on cancer treatment: literature review.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Simpson E, Bernaitis N, Khan S, Grant G, Forster K, Anoopkumar-Dukie S.
PMID: 34757445
Support Care Cancer. 2021 Nov 10; doi: 10.1007/s00520-021-06679-8. Epub 2021 Nov 10.

PURPOSE: This literature review examines the provision of an education on pharmacologically active complementary and alternative medicines (CAMs), to people with cancer, their carers and oncology health professionals.METHODS: A search of the published literature between 2000 and 2020, in...

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Simpson E, Bernaitis N, Khan S, et al. An education on pharmacologically active complementary and alternative medicine and its effects on cancer treatment: literature review. Support Care Cancer. 2021;doi: 10.1007/s00520-021-06679-8.
Simpson, E., Bernaitis, N., Khan, S., Grant, G., Forster, K., & Anoopkumar-Dukie, S. (2021). An education on pharmacologically active complementary and alternative medicine and its effects on cancer treatment: literature review. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, . https://doi.org/10.1007/s00520-021-06679-8
Simpson, Ellen, et al. "An education on pharmacologically active complementary and alternative medicine and its effects on cancer treatment: literature review." Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer vol. (2021). doi: https://doi.org/10.1007/s00520-021-06679-8
Simpson E, Bernaitis N, Khan S, Grant G, Forster K, Anoopkumar-Dukie S. An education on pharmacologically active complementary and alternative medicine and its effects on cancer treatment: literature review. Support Care Cancer. 2021 Nov 10; doi: 10.1007/s00520-021-06679-8. Epub 2021 Nov 10. PMID: 34757445.
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A review of the bioactivity of coffee, caffeine and key coffee constituents on inflammatory responses linked to depression.

Food research international (Ottawa, Ont.)

Hall S, Desbrow B, Anoopkumar-Dukie S, Davey AK, Arora D, McDermott C, Schubert MM, Perkins AV, Kiefel MJ, Grant GD.
PMID: 28455046
Food Res Int. 2015 Oct;76:626-636. doi: 10.1016/j.foodres.2015.07.027. Epub 2015 Aug 04.

Coffee is a widely consumed beverage containing numerous biologically active constituents predominantly belonging to the polyphenol and alkaloid classes. It has been established that coffee has a beneficial effect on numerous disease states including depression. A number of prospective...

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Hall S, Desbrow B, Anoopkumar-Dukie S, et al. A review of the bioactivity of coffee, caffeine and key coffee constituents on inflammatory responses linked to depression. Food Res Int. 2015;76:626-636doi: 10.1016/j.foodres.2015.07.027.
Hall, S., Desbrow, B., Anoopkumar-Dukie, S., Davey, A. K., Arora, D., McDermott, C., Schubert, M. M., Perkins, A. V., Kiefel, M. J., & Grant, G. D. (2015). A review of the bioactivity of coffee, caffeine and key coffee constituents on inflammatory responses linked to depression. Food research international (Ottawa, Ont.), 76626-636. https://doi.org/10.1016/j.foodres.2015.07.027
Hall, Susan, et al. "A review of the bioactivity of coffee, caffeine and key coffee constituents on inflammatory responses linked to depression." Food research international (Ottawa, Ont.) vol. 76 (2015): 626-636. doi: https://doi.org/10.1016/j.foodres.2015.07.027
Hall S, Desbrow B, Anoopkumar-Dukie S, Davey AK, Arora D, McDermott C, Schubert MM, Perkins AV, Kiefel MJ, Grant GD. A review of the bioactivity of coffee, caffeine and key coffee constituents on inflammatory responses linked to depression. Food Res Int. 2015 Oct;76:626-636. doi: 10.1016/j.foodres.2015.07.027. Epub 2015 Aug 04. PMID: 28455046.
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A Review of Black Salve: Cancer Specificity, Cure, and Cosmesis.

Evidence-based complementary and alternative medicine : eCAM

Croaker A, King GJ, Pyne JH, Anoopkumar-Dukie S, Liu L.
PMID: 28246541
Evid Based Complement Alternat Med. 2017;2017:9184034. doi: 10.1155/2017/9184034. Epub 2017 Jan 26.

Black salve is a topical escharotic used for the treatment of skin cancer. Although promoted as a safe and effective alternative to conventional management by its proponents, limited clinical research has been undertaken to assess its efficacy and potential...

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Croaker A, King GJ, Pyne JH, et al. A Review of Black Salve: Cancer Specificity, Cure, and Cosmesis. Evid Based Complement Alternat Med. 2017;2017:9184034doi: 10.1155/2017/9184034.
Croaker, A., King, G. J., Pyne, J. H., Anoopkumar-Dukie, S., & Liu, L. (2017). A Review of Black Salve: Cancer Specificity, Cure, and Cosmesis. Evidence-based complementary and alternative medicine : eCAM, 20179184034. https://doi.org/10.1155/2017/9184034
Croaker, Andrew, et al. "A Review of Black Salve: Cancer Specificity, Cure, and Cosmesis." Evidence-based complementary and alternative medicine : eCAM vol. 2017 (2017): 9184034. doi: https://doi.org/10.1155/2017/9184034
Croaker A, King GJ, Pyne JH, Anoopkumar-Dukie S, Liu L. A Review of Black Salve: Cancer Specificity, Cure, and Cosmesis. Evid Based Complement Alternat Med. 2017;2017:9184034. doi: 10.1155/2017/9184034. Epub 2017 Jan 26. PMID: 28246541; PMCID: PMC5299188.
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The Use of Fish Oil with Warfarin Does Not Significantly Affect either the International Normalised Ratio or Incidence of Adverse Events in Patients with Atrial Fibrillation and Deep Vein Thrombosis: A Retrospective Study.

Nutrients

Pryce R, Bernaitis N, Davey AK, Badrick T, Anoopkumar-Dukie S.
PMID: 27657121
Nutrients. 2016 Sep 20;8(9). doi: 10.3390/nu8090578.

BACKGROUND: Warfarin is a leading anticoagulant in the management of atrial fibrillation (AF) and deep vein thrombosis (DVT). Drug interactions influence the safety of warfarin use and while extensive literature exists regarding the effect on warfarin control and bleeding...

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Pryce R, Bernaitis N, Davey AK, et al. The Use of Fish Oil with Warfarin Does Not Significantly Affect either the International Normalised Ratio or Incidence of Adverse Events in Patients with Atrial Fibrillation and Deep Vein Thrombosis: A Retrospective Study. Nutrients. 2016;8(9)doi: 10.3390/nu8090578.
Pryce, R., Bernaitis, N., Davey, A. K., Badrick, T., & Anoopkumar-Dukie, S. (2016). The Use of Fish Oil with Warfarin Does Not Significantly Affect either the International Normalised Ratio or Incidence of Adverse Events in Patients with Atrial Fibrillation and Deep Vein Thrombosis: A Retrospective Study. Nutrients, 8(9), . https://doi.org/10.3390/nu8090578
Pryce, Rebecca, et al. "The Use of Fish Oil with Warfarin Does Not Significantly Affect either the International Normalised Ratio or Incidence of Adverse Events in Patients with Atrial Fibrillation and Deep Vein Thrombosis: A Retrospective Study." Nutrients vol. 8,9 (2016). doi: https://doi.org/10.3390/nu8090578
Pryce R, Bernaitis N, Davey AK, Badrick T, Anoopkumar-Dukie S. The Use of Fish Oil with Warfarin Does Not Significantly Affect either the International Normalised Ratio or Incidence of Adverse Events in Patients with Atrial Fibrillation and Deep Vein Thrombosis: A Retrospective Study. Nutrients. 2016 Sep 20;8(9). doi: 10.3390/nu8090578. PMID: 27657121; PMCID: PMC5037562.
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Comparison of potential pharmacokinetic drug interactions in patients with atrial fibrillation and changing from warfarin to non-vitamin K oral anticoagulant therapy.

Journal of thrombosis and thrombolysis

Bernaitis N, Badrick T, Anoopkumar-Dukie S.
PMID: 33963483
J Thromb Thrombolysis. 2021 Nov;52(4):1110-1116. doi: 10.1007/s11239-021-02466-8. Epub 2021 May 07.

There are now anticoagulant choices with proposed advantages of non-vitamin K oral anticoagulants (NOACs) over warfarin being less routine monitoring and less drug interactions. Interacting medication can impact the efficacy and safety of anticoagulant therapy with management remaining clinically...

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Bernaitis N, Badrick T, Anoopkumar-Dukie S. Comparison of potential pharmacokinetic drug interactions in patients with atrial fibrillation and changing from warfarin to non-vitamin K oral anticoagulant therapy. J Thromb Thrombolysis. 2021;52(4):1110-1116doi: 10.1007/s11239-021-02466-8.
Bernaitis, N., Badrick, T., & Anoopkumar-Dukie, S. (2021). Comparison of potential pharmacokinetic drug interactions in patients with atrial fibrillation and changing from warfarin to non-vitamin K oral anticoagulant therapy. Journal of thrombosis and thrombolysis, 52(4), 1110-1116. https://doi.org/10.1007/s11239-021-02466-8
Bernaitis, Nijole, et al. "Comparison of potential pharmacokinetic drug interactions in patients with atrial fibrillation and changing from warfarin to non-vitamin K oral anticoagulant therapy." Journal of thrombosis and thrombolysis vol. 52,4 (2021): 1110-1116. doi: https://doi.org/10.1007/s11239-021-02466-8
Bernaitis N, Badrick T, Anoopkumar-Dukie S. Comparison of potential pharmacokinetic drug interactions in patients with atrial fibrillation and changing from warfarin to non-vitamin K oral anticoagulant therapy. J Thromb Thrombolysis. 2021 Nov;52(4):1110-1116. doi: 10.1007/s11239-021-02466-8. Epub 2021 May 07. PMID: 33963483.
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Remedial effects of caffeine against depressive-like behaviour in mice by modulation of neuroinflammation and BDNF.

Nutritional neuroscience

Basu Mallik S, Mudgal J, Hall S, Kinra M, Grant GD, Nampoothiri M, Anoopkumar-Dukie S, Arora D.
PMID: 33814004
Nutr Neurosci. 2021 Apr 05;1-9. doi: 10.1080/1028415X.2021.1906393. Epub 2021 Apr 05.

No abstract available.

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Basu Mallik S, Mudgal J, Hall S, et al. Remedial effects of caffeine against depressive-like behaviour in mice by modulation of neuroinflammation and BDNF. Nutr Neurosci. 2021;1-9doi: 10.1080/1028415X.2021.1906393.
Basu Mallik, S., Mudgal, J., Hall, S., Kinra, M., Grant, G. D., Nampoothiri, M., Anoopkumar-Dukie, S., & Arora, D. (2021). Remedial effects of caffeine against depressive-like behaviour in mice by modulation of neuroinflammation and BDNF. Nutritional neuroscience, 1-9. https://doi.org/10.1080/1028415X.2021.1906393
Basu Mallik, Sanchari, et al. "Remedial effects of caffeine against depressive-like behaviour in mice by modulation of neuroinflammation and BDNF." Nutritional neuroscience vol. (2021): 1-9. doi: https://doi.org/10.1080/1028415X.2021.1906393
Basu Mallik S, Mudgal J, Hall S, Kinra M, Grant GD, Nampoothiri M, Anoopkumar-Dukie S, Arora D. Remedial effects of caffeine against depressive-like behaviour in mice by modulation of neuroinflammation and BDNF. Nutr Neurosci. 2021 Apr 05;1-9. doi: 10.1080/1028415X.2021.1906393. Epub 2021 Apr 05. PMID: 33814004.
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Prazosin but Not Tamsulosin Sensitises PC-3 and LNCaP Prostate Cancer Cells to Docetaxel.

Pharmacology

Spencer BH, McDermott CM, Chess-Williams R, Christie D, Anoopkumar-Dukie S.
PMID: 29669348
Pharmacology. 2018 Apr 17;102(1):10-18. doi: 10.1159/000488713. Epub 2018 Apr 17.

BACKGROUND/AIMS: Docetaxel is currently the first-line chemotherapeutic agent available for the treatment of patients with advanced prostate cancer (PCa). While docetaxel has been shown to modestly improve survival times for patients; they also experience significant docetaxel-induced toxicities. If treatment...

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Spencer BH, McDermott CM, Chess-Williams R, et al. Prazosin but Not Tamsulosin Sensitises PC-3 and LNCaP Prostate Cancer Cells to Docetaxel. Pharmacology. 2018;102(1):10-18doi: 10.1159/000488713.
Spencer, B. H., McDermott, C. M., Chess-Williams, R., Christie, D., & Anoopkumar-Dukie, S. (2018). Prazosin but Not Tamsulosin Sensitises PC-3 and LNCaP Prostate Cancer Cells to Docetaxel. Pharmacology, 102(1), 10-18. https://doi.org/10.1159/000488713
Spencer, Briohny H, et al. "Prazosin but Not Tamsulosin Sensitises PC-3 and LNCaP Prostate Cancer Cells to Docetaxel." Pharmacology vol. 102,1 (2018): 10-18. doi: https://doi.org/10.1159/000488713
Spencer BH, McDermott CM, Chess-Williams R, Christie D, Anoopkumar-Dukie S. Prazosin but Not Tamsulosin Sensitises PC-3 and LNCaP Prostate Cancer Cells to Docetaxel. Pharmacology. 2018 Apr 17;102(1):10-18. doi: 10.1159/000488713. Epub 2018 Apr 17. PMID: 29669348.
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Long-Term Statin Administration Does Not Affect Warfarin Time in Therapeutic Range in Australia or Singapore.

Journal of clinical medicine

Bernaitis N, Ching CK, Teo SC, Badrick T, Davey AK, Crilly J, Anoopkumar-Dukie S.
PMID: 29723987
J Clin Med. 2018 May 01;7(5). doi: 10.3390/jcm7050097.

BACKGROUND: Warfarin requires ongoing monitoring of the International Normalised Ratio (INR). This is because numerous factors influence the response, including drug interactions with commonly-prescribed medications, such as statins. The administration of statins with warfarin may change INR; however, there...

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Bernaitis N, Ching CK, Teo SC, et al. Long-Term Statin Administration Does Not Affect Warfarin Time in Therapeutic Range in Australia or Singapore. J Clin Med. 2018;7(5)doi: 10.3390/jcm7050097.
Bernaitis, N., Ching, C. K., Teo, S. C., Badrick, T., Davey, A. K., Crilly, J., & Anoopkumar-Dukie, S. (2018). Long-Term Statin Administration Does Not Affect Warfarin Time in Therapeutic Range in Australia or Singapore. Journal of clinical medicine, 7(5), . https://doi.org/10.3390/jcm7050097
Bernaitis, Nijole, et al. "Long-Term Statin Administration Does Not Affect Warfarin Time in Therapeutic Range in Australia or Singapore." Journal of clinical medicine vol. 7,5 (2018). doi: https://doi.org/10.3390/jcm7050097
Bernaitis N, Ching CK, Teo SC, Badrick T, Davey AK, Crilly J, Anoopkumar-Dukie S. Long-Term Statin Administration Does Not Affect Warfarin Time in Therapeutic Range in Australia or Singapore. J Clin Med. 2018 May 01;7(5). doi: 10.3390/jcm7050097. PMID: 29723987; PMCID: PMC5977136.
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Liraglutide modulates olfactory ensheathing cell migration with activation of ERK and alteration of the extracellular matrix.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Tseng YT, Chen M, Lai R, Oieni F, Smyth G, Anoopkumar-Dukie S, St John J, Ekberg J.
PMID: 34126351
Biomed Pharmacother. 2021 Sep;141:111819. doi: 10.1016/j.biopha.2021.111819. Epub 2021 Jun 11.

Transplantation of olfactory ensheathing cells (OECs) is a promising approach for repairing the injured nervous system that has been extensively trialed for nervous system repair. However, the method still needs improvement and optimization. One avenue of improving outcomes is...

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Tseng YT, Chen M, Lai R, et al. Liraglutide modulates olfactory ensheathing cell migration with activation of ERK and alteration of the extracellular matrix. Biomed Pharmacother. 2021;141:111819doi: 10.1016/j.biopha.2021.111819.
Tseng, Y. T., Chen, M., Lai, R., Oieni, F., Smyth, G., Anoopkumar-Dukie, S., St John, J., & Ekberg, J. (2021). Liraglutide modulates olfactory ensheathing cell migration with activation of ERK and alteration of the extracellular matrix. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 141111819. https://doi.org/10.1016/j.biopha.2021.111819
Tseng, Yu-Ting, et al. "Liraglutide modulates olfactory ensheathing cell migration with activation of ERK and alteration of the extracellular matrix." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 141 (2021): 111819. doi: https://doi.org/10.1016/j.biopha.2021.111819
Tseng YT, Chen M, Lai R, Oieni F, Smyth G, Anoopkumar-Dukie S, St John J, Ekberg J. Liraglutide modulates olfactory ensheathing cell migration with activation of ERK and alteration of the extracellular matrix. Biomed Pharmacother. 2021 Sep;141:111819. doi: 10.1016/j.biopha.2021.111819. Epub 2021 Jun 11. PMID: 34126351.
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Cyclooxygenase-2 inhibitors delay relapse and reduce Prostate Specific Antigen (PSA) velocity in patients treated with radiotherapy for nonmetastatic prostate cancer: a pilot study.

Prostate international

King L, Christie D, Arora D, Anoopkumar-Dukie S.
PMID: 32257976
Prostate Int. 2020 Mar;8(1):34-40. doi: 10.1016/j.prnil.2019.10.004. Epub 2019 Nov 30.

INTRODUCTION: A common treatment for localized prostate cancer (PCa) is radiotherapy; however, effectiveness is hampered because of toxicities and tumor resistance. Cyclooxygenase-2 (COX-2) inhibitors have been identified as potential agents that could improve treatment outcomes and have demonstrated ability...

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King L, Christie D, Arora D, et al. Cyclooxygenase-2 inhibitors delay relapse and reduce Prostate Specific Antigen (PSA) velocity in patients treated with radiotherapy for nonmetastatic prostate cancer: a pilot study. Prostate Int. 2019;8(1):34-40doi: 10.1016/j.prnil.2019.10.004.
King, L., Christie, D., Arora, D., & Anoopkumar-Dukie, S. (2020). Cyclooxygenase-2 inhibitors delay relapse and reduce Prostate Specific Antigen (PSA) velocity in patients treated with radiotherapy for nonmetastatic prostate cancer: a pilot study. Prostate international, 8(1), 34-40. https://doi.org/10.1016/j.prnil.2019.10.004
King, Liam, et al. "Cyclooxygenase-2 inhibitors delay relapse and reduce Prostate Specific Antigen (PSA) velocity in patients treated with radiotherapy for nonmetastatic prostate cancer: a pilot study." Prostate international vol. 8,1 (2020): 34-40. doi: https://doi.org/10.1016/j.prnil.2019.10.004
King L, Christie D, Arora D, Anoopkumar-Dukie S. Cyclooxygenase-2 inhibitors delay relapse and reduce Prostate Specific Antigen (PSA) velocity in patients treated with radiotherapy for nonmetastatic prostate cancer: a pilot study. Prostate Int. 2020 Mar;8(1):34-40. doi: 10.1016/j.prnil.2019.10.004. Epub 2019 Nov 30. PMID: 32257976; PMCID: PMC7125379.
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