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Showing 1 to 10 of 10 entries
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Facile preparation and photophysics of near-infrared luminescent lanthanide(III) monoporphyrinate complexes.

Inorganic chemistry

Foley TJ, Harrison BS, Knefely AS, Abboud KA, Reynolds JR, Schanze KS, Boncella JM.
PMID: 12895128
Inorg Chem. 2003 Aug 11;42(16):5023-32. doi: 10.1021/ic034217g.

The synthesis, characterization, and single crystal X-ray diffraction structures of a series of monoporphyrinate, trivalent lanthanide complexes with the monoanionic ligands hydridotris(1-pyrazolyl)borate (Tp) and (cyclopentadienyl)tris(diethylphosphinito)cobaltate (L(OEt)) having the general formulas M(TPP)(L) (M = Yb, Tm, Er, Ho, Nd, Pr;...

A Tethered Porphyrin Dimer with π Overlap of a Single Pyrrole Ring.

Angewandte Chemie (International ed. in English)

Knapp S, Vasudevan J, Emge TJ, Arison BH, Potenza JA, Schugar HJ.
PMID: 29710963
Angew Chem Int Ed Engl. 1998 Sep 18;37(17):2368-2370. doi: 10.1002/(SICI)1521-3773(19980918)37:17<2368::AID-ANIE2368>3.0.CO;2-K.

The special pair of the bacterial photosystem has been modeled with a porphyrin dimer (the partial structure is shown). As with the natural system, only one pyrrole ring from each monomer subunit participates in π overlap.

Synthesis of 1,19-Aza-1,19-desoxy-avermectin B(1a): The First Avermectin Macrolactam.

The Journal of organic chemistry

Meinke PT, Arison B, Culberson JC, Fisher MH, Mrozik H.
PMID: 11672123
J Org Chem. 1998 Apr 17;63(8):2591-2596. doi: 10.1021/jo972094+.

The first synthesis of 1,19-aza-1,19-desoxy-avermectin B(1a) (2) is described. This new macrolactam, prepared efficiently from avermectin B(1a) (1a) in seven steps, was designed to form an intramolecular hydrogen bond between the amide carbonyl and the adjacent C7 tertiary hydroxyl...

Achieving Acetylcholine Receptor Clustering in Tissue-Engineered Skeletal Muscle Constructs .

Frontiers in pharmacology

Scott JB, Ward CL, Corona BT, Deschenes MR, Harrison BS, Saul JM, Christ GJ.
PMID: 28123368
Front Pharmacol. 2017 Jan 11;7:508. doi: 10.3389/fphar.2016.00508. eCollection 2016.

Volumetric muscle loss (VML) can result from trauma, infection, congenital anomalies, or surgery, and produce permanent functional and cosmetic deficits. There are no effective treatment options for VML injuries, and recent advances toward development of muscle constructs lack the...

Effect of pulsed electromagnetic field on inflammatory pathway markers in RAW 264.7 murine macrophages.

Journal of inflammation research

Ross CL, Harrison BS.
PMID: 23576877
J Inflamm Res. 2013;6:45-51. doi: 10.2147/JIR.S40269. Epub 2013 Mar 12.

In the treatment of bacterial infections, antibiotics have proven to be very effective, but the way in which antibiotics are dosed can create a lag time between the administration of the drug and its absorption at the site of...

Release of serotonin from nerve endings byL-5-hydroxytryptophan,α-methyl-m-tyramine, and elevated potassium ions.

Neurochemical research

McBride WJ, Aprison MH.
PMID: 24271411
Neurochem Res. 1976 Jun;1(3):233-49. doi: 10.1007/BF00973771.

The release of [(3)H]5-hydroxytryptamine ([(3)H]5-HT) byL-5-hydroxytryptophan (L-5-HTP),α-methyl-m-tyramine (α-MMTA), and elevated levels of K(+) was studied using crude synaptosomal preparations (P2) isolated from the telencephalon of the rat and pigeon. Studies were conducted in vitro in the presence of either...

Effects of selective doses of x-irradiation on the levels of several amino acids in the cerebellum of the rat.

Neurochemical research

McBride WJ, Nadi NS, Altman J, Aprison MH.
PMID: 24271338
Neurochem Res. 1976 Apr;1(2):141-52. doi: 10.1007/BF00966106.

The cerebella of rats were exposed to selective doses of low levels of x-irradiation beginning on day 4, 8, or 12 following birth. The doses of x-irradiation given on days 12, 13, and 15 (12-15X group) resulted in a...

Protocol and cell responses in three-dimensional conductive collagen gel scaffolds with conductive polymer nanofibres for tissue regeneration.

Interface focus

Sirivisoot S, Pareta R, Harrison BS.
PMID: 24501678
Interface Focus. 2014 Feb 06;4(1):20130050. doi: 10.1098/rsfs.2013.0050.

It has been established that nerves and skeletal muscles respond and communicate via electrical signals. In regenerative medicine, there is current emphasis on using conductive nanomaterials to enhance electrical conduction through tissue-engineered scaffolds to increase cell differentiation and tissue...

Reactive oxygen species resulting from mitochondrial mutation diminishes stem and progenitor cell function.

Cell metabolism

Garrison BS, Rossi DJ.
PMID: 22225868
Cell Metab. 2012 Jan 04;15(1):2-3. doi: 10.1016/j.cmet.2011.12.008.

While age-dependent stem cell decline is widely recognized as being a key component of organismal aging, the underlying mechanisms remain elusive. In this issue of Cell Metabolism, Suomalainen and colleagues provide evidence that mitochondrial mutation and associated reactive oxygen...

SENTI-101, a Preparation of Mesenchymal Stromal Cells Engineered to Express IL12 and IL21, Induces Localized and Durable Antitumor Immunity in Preclinical Models of Peritoneal Solid Tumors.

Molecular cancer therapeutics

Gonzalez-Junca A, Liu FD, Nagaraja AS, Mullenix A, Lee CT, Gordley RM, Frimannsson DO, Maller O, Garrison BS, Iyer D, Benabbas A, Truong TA, Quach A, Tian M, Martinez R, Savur R, Perry-McNamara A, Nguyen D, Almudhfar N, Blanco C, Huynh C, Nand A, Lay YE, Magal A, Mangalampalli S, Lee PJ, Lu TK, Lee G, Whitt-Glover MC, Marquez DX.
PMID: 34210826
Mol Cancer Ther. 2021 Sep;20(9):1508-1520. doi: 10.1158/1535-7163.MCT-21-0030. Epub 2021 Jul 01.

Advanced peritoneal carcinomatosis including high-grade ovarian cancer has poor prognoses and a poor response rate to current checkpoint inhibitor immunotherapies; thus, there is an unmet need for effective therapeutics that would provide benefit to these patients. Here we present...

Showing 1 to 10 of 10 entries