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Showing 1 to 12 of 190 entries
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Maraviroc Intensification Improves Endothelial Function in Abacavir-Treated Patients, an Open-Label Randomized Cross-Over Pilot Study.

Infectious diseases and therapy

Krikke M, Tesselaar K, Arends JE, Drylewicz J, Otto SA, van Lelyveld SF, Visseren FJ, Hoepelman AI.
PMID: 27300170
Infect Dis Ther. 2016 Sep;5(3):389-404. doi: 10.1007/s40121-016-0115-0. Epub 2016 Jun 14.

BACKGROUND: The increased risk of abacavir in cardiovascular disease (CVD) in HIV-infected patients is still being debated. Maraviroc, a CCR5 blocker, has been shown to decrease immune activation and monocyte infiltration in atherosclerotic plaques in murine experiments. Therefore, we...

New Viral and Immunological Targets for Hepatitis B Treatment and Cure: A Review.

Infectious diseases and therapy

Arends JE, Lieveld FI, Ahmad S, Ustianowski A.
PMID: 29071665
Infect Dis Ther. 2017 Dec;6(4):461-476. doi: 10.1007/s40121-017-0173-y. Epub 2017 Oct 25.

Although current therapies can be successful at suppressing hepatitis B viral load, long-term viral cure is not within reach. Subsequent strategies combining pegylated interferon alfa with nucleoside/nucleotide analogues have not resulted in any major paradigm shift. An improved understanding...

Measurements of double-polarized compton scattering asymmetries and extraction of the proton spin polarizabilities.

Physical review letters

Martel PP, Miskimen R, Aguar-Bartolome P, Ahrens J, Akondi CS, Annand JR, Arends HJ, Barnes W, Beck R, Bernstein A, Borisov N, Braghieri A, Briscoe WJ, Cherepnya S, Collicott C, Costanza S, Denig A, Dieterle M, Downie EJ, Fil'kov LV, Garni S, Glazier DI, Gradl W, Gurevich G, Hall Barrientos P, Hamilton D, Hornidge D, Howdle D, Huber GM, Jude TC, Kaeser A, Kashevarov VL, Keshelashvili I, Kondratiev R, Korolija M, Krusche B, Lazarev A, Lisin V, Livingston K, MacGregor IJ, Mancell J, Manley DM, Meyer W, Middleton DG, Mushkarenkov A, Nefkens BM, Neganov A, Nikolaev A, Oberle M, Ortega Spina H, Ostrick M, Ott P, Otte PB, Oussena B, Pedroni P, Polonski A, Polyansky V, Prakhov S, Rajabi A, Reicherz G, Rostomyan T, Sarty A, Schrauf S, Schumann S, Sikora MH, Starostin A, Steffen O, Strakovsky II, Strub T, Supek I, Thiel M, Tiator L, Thomas A, Unverzagt M, Usov Y, Watts DP, Witthauer L, Werthmüller D, Wolfes M.
PMID: 25839263
Phys Rev Lett. 2015 Mar 20;114(11):112501. doi: 10.1103/PhysRevLett.114.112501. Epub 2015 Mar 19.

The spin polarizabilities of the nucleon describe how the spin of the nucleon responds to an incident polarized photon. The most model-independent way to extract the nucleon spin polarizabilities is through polarized Compton scattering. Double-polarized Compton scattering asymmetries on...

Pain Incidence and Analgesic Consumption During Haemodialysis Sessions: Impact on Health-Related Quality Of Life.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Rebollo P, Arenas MD, Castejón N, Reichert GJ, Delgado CP, Gutierrez RP, Gil GM.
PMID: 27201632
Value Health. 2014 Nov;17(7):A521-2. doi: 10.1016/j.jval.2014.08.1631. Epub 2014 Oct 26.

No abstract available.

PP004. The polymorphism C677T of methylenetetrahydrofolate reductase (MTHFR), may increase risk for future higher blood pressure in women with previous hypertension in pregnancy.

Pregnancy hypertension

Matos A, da Silva AP, Maia H, Ferreira J, Clode N, Areias MJ, Bicho MC, Bicho M, Rebelo I.
PMID: 26105861
Pregnancy Hypertens. 2013 Apr;3(2):69. doi: 10.1016/j.preghy.2013.04.032. Epub 2013 Jun 06.

INTRODUCTION: The MTHFR is a key enzyme in the folate cycle involved in homocysteine remethylation. The T allele of MTHFR C677T polymorphism is associated with lower activity inhibiting the DNA methylation and protecting from oxidative stress.OBJECTIVES: To evaluate the...

Selenium-catalyzed oxidations with aqueous hydrogen peroxide. 2. Baeyer-Villiger reactions in homogeneous solution.

The Journal of organic chemistry

ten Brink GJ, Vis JM, Arends IW, Sheldon RA.
PMID: 11281784
J Org Chem. 2001 Apr 06;66(7):2429-33. doi: 10.1021/jo0057710.

Several diselenides were tested for catalytic activity in Baeyer-Villiger reactions with 60% aqueous hydrogen peroxide. Bis[3,5-bis(trifluoromethyl)phenyl] diselenide forms the corresponding 3,5-bis(trifluoromethyl)benzene seleninic acid in situ, which is a highly reactive and selective catalyst for the oxidation of carbonyl compounds...

The Baeyer-Villiger reaction: new developments toward greener procedures.

Chemical reviews

ten Brink GJ, Arends IW, Sheldon RA.
PMID: 15352787
Chem Rev. 2004 Sep;104(9):4105-24. doi: 10.1021/cr030011l.

No abstract available.

Efficient immobilisation of Rh-MonoPhos on the aluminosilicate AlTUD-1.

Chemical communications (Cambridge, England)

Simons C, Hanefeld U, Arends IW, Minnaard AJ, Maschmeyer T, Sheldon RA.
PMID: 15599428
Chem Commun (Camb). 2004 Dec 21;(24):2830-1. doi: 10.1039/b411506f. Epub 2004 Oct 26.

Rhodium-MonoPhos was successfully immobilised by ionic interactions on aluminosilicate AlTUD-1. The resulting new heterogeneous catalyst can be used in water and showed excellent enantioselectivity and activity in the asymmetric hydrogenation of methyl-2-acetamidoacrylate.

Photoinduced charge separation in self-assembled cofacial pentamers of zinc-5,10,15,20-tetrakis(perylenediimide)porphyrin.

Physical chemistry chemical physics : PCCP

Ahrens MJ, Kelley RF, Dance ZE, Wasielewski MR.
PMID: 17356754
Phys Chem Chem Phys. 2007 Mar 28;9(12):1469-78. doi: 10.1039/b617876f. Epub 2007 Feb 22.

A bichromophoric electron donor-acceptor molecule composed of a zinc tetraphenylporphyrin (ZnTPP) surrounded by four perylene-3,4:9,10-bis(dicarboximide)(PDI) chromophores (ZnTPP-PDI(4)) was synthesized. The properties of this molecule were compared to a reference molecule having ZnTPP covalently bound to a single PDI (ZnTPP-PDI)....

Synthesis of conducting polyaniline nanofibers from single and binary dopant agents.

Journal of nanoscience and nanotechnology

Arenas MC, Andablo E, Castaño VM.
PMID: 20352890
J Nanosci Nanotechnol. 2010 Jan;10(1):549-54. doi: 10.1166/jnn.2010.1721.

Conducting polyaniline nanofibers (nf-PANI) were successfully synthesized by simple polymerization of aniline in presence of single and binary dopant agents. Strong hydrochloride acid (HCl), two weak organic acids (poly acrylic acid, PAA, 2-acrylamido-2-methyl-1-propanesulfonic acid, AMPSA) and one anionic surfactant...

Bis(n-octylamino)perylene-3,4:9,10-bis(dicarboximide)s and their radical cations: synthesis, electrochemistry, and ENDOR spectroscopy.

The Journal of organic chemistry

Ahrens MJ, Tauber MJ, Wasielewski MR.
PMID: 16496999
J Org Chem. 2006 Mar 03;71(5):2107-14. doi: 10.1021/jo052394o.

1,6- and 1,7-bis(n-octylamino)perylene-3,4:9,10-bis(dicarboximide) were synthesized by reaction of n-octylamine with the corresponding dibromo compounds. These compounds display intense charge-transfer optical transitions in the visible spectrum (approximately 550-750 nm) and fluoresce weakly (Phi(F) < 0.06). Cyclic voltammetry reveals that each...

High frequency microsatellite instability has a prognostic value in endometrial endometrioid adenocarcinoma, but only in FIGO stage 1 cases.

Cellular oncology (Dordrecht)

Steinbakk A, Malpica A, Slewa A, Gudlaugsson E, Janssen EA, Arends M, Kruse AJ, Yinhua Y, Feng W, Baak JP.
PMID: 21547578
Cell Oncol (Dordr). 2011 Oct;34(5):457-65. doi: 10.1007/s13402-011-0040-x. Epub 2011 May 06.

OBJECTIVES: To analyze the prognostic value of microsatellite instability (MSI) in a population-based study of FIGO stage 1-4 endometrial endometrioid adenocarcinomas.STUDY DESIGN: Survival analysis in 273 patients of MSI status and clinico-pathologic features. Using a highly sensitive pentaplex polymerase...

Showing 1 to 12 of 190 entries