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Showing 1 to 12 of 38 entries
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Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons.

JAMA psychiatry

Yu L, Tasaki S, Schneider JA, Arfanakis K, Duong DM, Wingo AP, Wingo TS, Kearns N, Thatcher GRJ, Seyfried NT, Levey AI, De Jager PL, Bennett DA.
PMID: 32609320
JAMA Psychiatry. 2020 Nov 01;77(11):1172-1180. doi: 10.1001/jamapsychiatry.2020.1807.

IMPORTANCE: Identifying genes and proteins for cognitive resilience (ie, targets that may be associated with slowing or preventing cognitive decline regardless of the presence, number, or combination of common neuropathologic conditions) provides a complementary approach to developing novel therapeutics...

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Yu L, Tasaki S, Schneider JA, et al. Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. JAMA Psychiatry. 2020;77(11):1172-1180doi: 10.1001/jamapsychiatry.2020.1807.
Yu, L., Tasaki, S., Schneider, J. A., Arfanakis, K., Duong, D. M., Wingo, A. P., Wingo, T. S., Kearns, N., Thatcher, G. R. J., Seyfried, N. T., Levey, A. I., De Jager, P. L., & Bennett, D. A. (2020). Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. JAMA psychiatry, 77(11), 1172-1180. https://doi.org/10.1001/jamapsychiatry.2020.1807
Yu, Lei, et al. "Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons." JAMA psychiatry vol. 77,11 (2020): 1172-1180. doi: https://doi.org/10.1001/jamapsychiatry.2020.1807
Yu L, Tasaki S, Schneider JA, Arfanakis K, Duong DM, Wingo AP, Wingo TS, Kearns N, Thatcher GRJ, Seyfried NT, Levey AI, De Jager PL, Bennett DA. Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. JAMA Psychiatry. 2020 Nov 01;77(11):1172-1180. doi: 10.1001/jamapsychiatry.2020.1807. PMID: 32609320; PMCID: PMC7330835.
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Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons.

Brain pathology (Zurich, Switzerland)

Agrawal S, Yu L, Kapasi A, James BD, Arfanakis K, Barnes LL, Bennett DA, Nag S, Schneider JA.
PMID: 33624322
Brain Pathol. 2021 May;31(3):e12939. doi: 10.1111/bpa.12939. Epub 2021 Feb 23.

Limbic-predominant age-related transactive response DNA-binding protein 43 (TDP-43) encephalopathy neuropathologic change (LATE-NC) and microvascular pathologies, including microinfarcts, cerebral amyloid angiopathy (CAA), and arteriolosclerosis are common in old age. A relationship between LATE-NC and arteriolosclerosis has been reported in some...

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Agrawal S, Yu L, Kapasi A, et al. Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons. Brain Pathol. 2021;31(3):e12939doi: 10.1111/bpa.12939.
Agrawal, S., Yu, L., Kapasi, A., James, B. D., Arfanakis, K., Barnes, L. L., Bennett, D. A., Nag, S., & Schneider, J. A. (2021). Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons. Brain pathology (Zurich, Switzerland), 31(3), e12939. https://doi.org/10.1111/bpa.12939
Agrawal, Sonal, et al. "Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons." Brain pathology (Zurich, Switzerland) vol. 31,3 (2021): e12939. doi: https://doi.org/10.1111/bpa.12939
Agrawal S, Yu L, Kapasi A, James BD, Arfanakis K, Barnes LL, Bennett DA, Nag S, Schneider JA. Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons. Brain Pathol. 2021 May;31(3):e12939. doi: 10.1111/bpa.12939. Epub 2021 Feb 23. PMID: 33624322; PMCID: PMC8363209.
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Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline.

Stroke

Lamar M, Leurgans S, Kapasi A, Barnes LL, Boyle PA, Bennett DA, Arfanakis K, Schneider JA.
PMID: 34601898
Stroke. 2021 Oct 04;STROKEAHA121034814. doi: 10.1161/STROKEAHA.121.034814. Epub 2021 Oct 04.

BACKGROUND AND PURPOSE: Cerebrovascular disease (CVD) pathologies including vessel disease (atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy) and tissue injury (macroinfarcts and microinfarcts) each contribute to Alzheimer and other forms of dementia. CVD is often a complex mix of neuropathologies,...

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Lamar M, Leurgans S, Kapasi A, et al. Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline. Stroke. 2021;STROKEAHA121034814doi: 10.1161/STROKEAHA.121.034814.
Lamar, M., Leurgans, S., Kapasi, A., Barnes, L. L., Boyle, P. A., Bennett, D. A., Arfanakis, K., & Schneider, J. A. (2021). Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline. Stroke, STROKEAHA121034814. https://doi.org/10.1161/STROKEAHA.121.034814
Lamar, Melissa, et al. "Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline." Stroke vol. (2021): STROKEAHA121034814. doi: https://doi.org/10.1161/STROKEAHA.121.034814
Lamar M, Leurgans S, Kapasi A, Barnes LL, Boyle PA, Bennett DA, Arfanakis K, Schneider JA. Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline. Stroke. 2021 Oct 04;STROKEAHA121034814. doi: 10.1161/STROKEAHA.121.034814. Epub 2021 Oct 04. PMID: 34601898.
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Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia.

Neurobiology of aging

Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Poole VN, Han SD, Yu L, Lamar M, Kim N, Bennett DA, Barnes LL.
PMID: 34963062
Neurobiol Aging. 2021 Nov 20;111:35-43. doi: 10.1016/j.neurobiolaging.2021.11.003. Epub 2021 Nov 20.

Blacks are at higher risk of developing cognitive impairment with age than non-Hispanic Whites, yet most brain morphometry and cognition research is performed with White samples or with mixed samples that control for race or compare across racial groups....

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Fleischman DA, Arfanakis K, Leurgans SE, et al. Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiol Aging. 2021;111:35-43doi: 10.1016/j.neurobiolaging.2021.11.003.
Fleischman, D. A., Arfanakis, K., Leurgans, S. E., Zhang, S., Poole, V. N., Han, S. D., Yu, L., Lamar, M., Kim, N., Bennett, D. A., & Barnes, L. L. (2021). Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiology of aging, 11135-43. https://doi.org/10.1016/j.neurobiolaging.2021.11.003
Fleischman, Debra A, et al. "Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia." Neurobiology of aging vol. 111 (2021): 35-43. doi: https://doi.org/10.1016/j.neurobiolaging.2021.11.003
Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Poole VN, Han SD, Yu L, Lamar M, Kim N, Bennett DA, Barnes LL. Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiol Aging. 2021 Nov 20;111:35-43. doi: 10.1016/j.neurobiolaging.2021.11.003. Epub 2021 Nov 20. PMID: 34963062.
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Application of Ultraviolet-Visible Absorption Spectroscopy with Machine Learning Techniques for the Classification of Cretan Wines.

Foods (Basel, Switzerland)

Philippidis A, Poulakis E, Kontzedaki R, Orfanakis E, Symianaki A, Zoumi A, Velegrakis M.
PMID: 33375212
Foods. 2020 Dec 22;10(1). doi: 10.3390/foods10010009.

The present study was aimed at the identification, differentiation and characterization of red and white Cretan wines, which are described with Protected Geographical Indication (PGI), using ultraviolet-visible absorption spectroscopy. Specifically, the grape variety, the wine aging process and the...

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Philippidis A, Poulakis E, Kontzedaki R, et al. Application of Ultraviolet-Visible Absorption Spectroscopy with Machine Learning Techniques for the Classification of Cretan Wines. Foods. 2020;10(1)doi: 10.3390/foods10010009.
Philippidis, A., Poulakis, E., Kontzedaki, R., Orfanakis, E., Symianaki, A., Zoumi, A., & Velegrakis, M. (2020). Application of Ultraviolet-Visible Absorption Spectroscopy with Machine Learning Techniques for the Classification of Cretan Wines. Foods (Basel, Switzerland), 10(1), . https://doi.org/10.3390/foods10010009
Philippidis, Aggelos, et al. "Application of Ultraviolet-Visible Absorption Spectroscopy with Machine Learning Techniques for the Classification of Cretan Wines." Foods (Basel, Switzerland) vol. 10,1 (2020). doi: https://doi.org/10.3390/foods10010009
Philippidis A, Poulakis E, Kontzedaki R, Orfanakis E, Symianaki A, Zoumi A, Velegrakis M. Application of Ultraviolet-Visible Absorption Spectroscopy with Machine Learning Techniques for the Classification of Cretan Wines. Foods. 2020 Dec 22;10(1). doi: 10.3390/foods10010009. PMID: 33375212; PMCID: PMC7822163.
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Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging.

JAMA neurology

Oveisgharan S, Yu L, Poole VN, Evia AM, Barnes LL, Schneider JA, Arfanakis K, Bennett DA, Buchman AS.
PMID: 34724033
JAMA Neurol. 2021 Dec 01;78(12):1494-1502. doi: 10.1001/jamaneurol.2021.3996.

IMPORTANCE: Progressive parkinsonism is common in older adults without a diagnosis of Parkinson disease and is associated with adverse health outcomes, but its pathologic basis is controversial.OBJECTIVE: To examine if the burden of cerebral white matter hyperintensity (WMH), a...

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Oveisgharan S, Yu L, Poole VN, et al. Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging. JAMA Neurol. 2021;78(12):1494-1502doi: 10.1001/jamaneurol.2021.3996.
Oveisgharan, S., Yu, L., Poole, V. N., Evia, A. M., Barnes, L. L., Schneider, J. A., Arfanakis, K., Bennett, D. A., & Buchman, A. S. (2021). Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging. JAMA neurology, 78(12), 1494-1502. https://doi.org/10.1001/jamaneurol.2021.3996
Oveisgharan, Shahram, et al. "Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging." JAMA neurology vol. 78,12 (2021): 1494-1502. doi: https://doi.org/10.1001/jamaneurol.2021.3996
Oveisgharan S, Yu L, Poole VN, Evia AM, Barnes LL, Schneider JA, Arfanakis K, Bennett DA, Buchman AS. Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging. JAMA Neurol. 2021 Dec 01;78(12):1494-1502. doi: 10.1001/jamaneurol.2021.3996. PMID: 34724033; PMCID: PMC8561430.
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Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia.

Neurobiology of aging

Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Poole VN, Han SD, Yu L, Lamar M, Kim N, Bennett DA, Barnes LL.
PMID: 34963062
Neurobiol Aging. 2021 Nov 20;111:35-43. doi: 10.1016/j.neurobiolaging.2021.11.003. Epub 2021 Nov 20.

Blacks are at higher risk of developing cognitive impairment with age than non-Hispanic Whites, yet most brain morphometry and cognition research is performed with White samples or with mixed samples that control for race or compare across racial groups....

Cite
Fleischman DA, Arfanakis K, Leurgans SE, et al. Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiol Aging. 2021;111:35-43doi: 10.1016/j.neurobiolaging.2021.11.003.
Fleischman, D. A., Arfanakis, K., Leurgans, S. E., Zhang, S., Poole, V. N., Han, S. D., Yu, L., Lamar, M., Kim, N., Bennett, D. A., & Barnes, L. L. (2021). Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiology of aging, 11135-43. https://doi.org/10.1016/j.neurobiolaging.2021.11.003
Fleischman, Debra A, et al. "Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia." Neurobiology of aging vol. 111 (2021): 35-43. doi: https://doi.org/10.1016/j.neurobiolaging.2021.11.003
Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Poole VN, Han SD, Yu L, Lamar M, Kim N, Bennett DA, Barnes LL. Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiol Aging. 2021 Nov 20;111:35-43. doi: 10.1016/j.neurobiolaging.2021.11.003. Epub 2021 Nov 20. PMID: 34963062.
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Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain.

NeuroImage

Niaz MR, Ridwan AR, Wu Y, Bennett DA, Arfanakis K.
PMID: 34986396
Neuroimage. 2022 Jan 02;248:118869. doi: 10.1016/j.neuroimage.2021.118869. Epub 2022 Jan 02.

Investigating the structure of the older adult brain at high spatial resolution is of high significance, and a dedicated older adult structural brain template with sub-millimeter resolution is currently lacking. Therefore, the purpose of this work was twofold: (A)...

Cite
Niaz MR, Ridwan AR, Wu Y. Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain. Neuroimage. 2022;248:118869doi: 10.1016/j.neuroimage.2021.118869.
Niaz, M. R., Ridwan, A. R., Wu, Y., Bennett, D. A., & Arfanakis, K. (2022). Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain. NeuroImage, 248118869. https://doi.org/10.1016/j.neuroimage.2021.118869
Niaz, Mohammad Rakeen, et al. "Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain." NeuroImage vol. 248 (2022): 118869. doi: https://doi.org/10.1016/j.neuroimage.2021.118869
Niaz MR, Ridwan AR, Wu Y, Bennett DA, Arfanakis K. Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain. Neuroimage. 2022 Jan 02;248:118869. doi: 10.1016/j.neuroimage.2021.118869. Epub 2022 Jan 02. PMID: 34986396.
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Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline.

Stroke

Lamar M, Leurgans S, Kapasi A, Barnes LL, Boyle PA, Bennett DA, Arfanakis K, Schneider JA.
PMID: 34601898
Stroke. 2022 Jan;53(1):218-227. doi: 10.1161/STROKEAHA.121.034814. Epub 2021 Oct 04.

BACKGROUND AND PURPOSE: Cerebrovascular disease (CVD) pathologies including vessel disease (atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy) and tissue injury (macroinfarcts and microinfarcts) each contribute to Alzheimer and other forms of dementia. CVD is often a complex mix of neuropathologies,...

Cite
Lamar M, Leurgans S, Kapasi A, et al. Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline. Stroke. 2021;53(1):218-227doi: 10.1161/STROKEAHA.121.034814.
Lamar, M., Leurgans, S., Kapasi, A., Barnes, L. L., Boyle, P. A., Bennett, D. A., Arfanakis, K., & Schneider, J. A. (2022). Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline. Stroke, 53(1), 218-227. https://doi.org/10.1161/STROKEAHA.121.034814
Lamar, Melissa, et al. "Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline." Stroke vol. 53,1 (2022): 218-227. doi: https://doi.org/10.1161/STROKEAHA.121.034814
Lamar M, Leurgans S, Kapasi A, Barnes LL, Boyle PA, Bennett DA, Arfanakis K, Schneider JA. Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline. Stroke. 2022 Jan;53(1):218-227. doi: 10.1161/STROKEAHA.121.034814. Epub 2021 Oct 04. PMID: 34601898; PMCID: PMC8712368.
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8-Hydroxy-2'-Deoxyguanosine and 8-Nitroguanine Production and Detection in Blood Serum of Breast Cancer Patients in Response to Postoperative Complementary External Ionizing Irradiation of Normal Tissues.

Dose-response : a publication of International Hormesis Society

Verigos KE, Sagredou S, Orfanakos K, Dalezis P, Trafalis DT.
PMID: 33424517
Dose Response. 2020 Dec 22;18(4):1559325820982172. doi: 10.1177/1559325820982172. eCollection 2020.

It is widely known that ionizing irradiation is strongly linked to the production of reactive oxygen (ROS) and nitrative species (RNS) through which DNA damage products like 8-hydroxy-2-deoxyguanosine (8-OHdG) and 8-nitroguanine (8-NG) are generated, respectively. In the present study,...

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Verigos KE, Sagredou S, Orfanakos K, et al. 8-Hydroxy-2'-Deoxyguanosine and 8-Nitroguanine Production and Detection in Blood Serum of Breast Cancer Patients in Response to Postoperative Complementary External Ionizing Irradiation of Normal Tissues. Dose Response. 2020;18(4):1559325820982172doi: 10.1177/1559325820982172.
Verigos, K. E., Sagredou, S., Orfanakos, K., Dalezis, P., & Trafalis, D. T. (2020). 8-Hydroxy-2'-Deoxyguanosine and 8-Nitroguanine Production and Detection in Blood Serum of Breast Cancer Patients in Response to Postoperative Complementary External Ionizing Irradiation of Normal Tissues. Dose-response : a publication of International Hormesis Society, 18(4), 1559325820982172. https://doi.org/10.1177/1559325820982172
Verigos, Kosmas E, et al. "8-Hydroxy-2'-Deoxyguanosine and 8-Nitroguanine Production and Detection in Blood Serum of Breast Cancer Patients in Response to Postoperative Complementary External Ionizing Irradiation of Normal Tissues." Dose-response : a publication of International Hormesis Society vol. 18,4 (2020): 1559325820982172. doi: https://doi.org/10.1177/1559325820982172
Verigos KE, Sagredou S, Orfanakos K, Dalezis P, Trafalis DT. 8-Hydroxy-2'-Deoxyguanosine and 8-Nitroguanine Production and Detection in Blood Serum of Breast Cancer Patients in Response to Postoperative Complementary External Ionizing Irradiation of Normal Tissues. Dose Response. 2020 Dec 22;18(4):1559325820982172. doi: 10.1177/1559325820982172. eCollection 2020. PMID: 33424517; PMCID: PMC7758665.
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Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain.

NeuroImage

Niaz MR, Ridwan AR, Wu Y, Bennett DA, Arfanakis K.
PMID: 34986396
Neuroimage. 2022 Jan 02;248:118869. doi: 10.1016/j.neuroimage.2021.118869. Epub 2022 Jan 02.

Investigating the structure of the older adult brain at high spatial resolution is of high significance, and a dedicated older adult structural brain template with sub-millimeter resolution is currently lacking. Therefore, the purpose of this work was twofold: (A)...

Cite
Niaz MR, Ridwan AR, Wu Y. Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain. Neuroimage. 2022;248:118869doi: 10.1016/j.neuroimage.2021.118869.
Niaz, M. R., Ridwan, A. R., Wu, Y., Bennett, D. A., & Arfanakis, K. (2022). Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain. NeuroImage, 248118869. https://doi.org/10.1016/j.neuroimage.2021.118869
Niaz, Mohammad Rakeen, et al. "Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain." NeuroImage vol. 248 (2022): 118869. doi: https://doi.org/10.1016/j.neuroimage.2021.118869
Niaz MR, Ridwan AR, Wu Y, Bennett DA, Arfanakis K. Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain. Neuroimage. 2022 Jan 02;248:118869. doi: 10.1016/j.neuroimage.2021.118869. Epub 2022 Jan 02. PMID: 34986396.
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Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia.

Neurobiology of aging

Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Poole VN, Han SD, Yu L, Lamar M, Kim N, Bennett DA, Barnes LL.
PMID: 34963062
Neurobiol Aging. 2022 Mar;111:35-43. doi: 10.1016/j.neurobiolaging.2021.11.003. Epub 2021 Nov 20.

Blacks are at higher risk of developing cognitive impairment with age than non-Hispanic Whites, yet most brain morphometry and cognition research is performed with White samples or with mixed samples that control for race or compare across racial groups....

Cite
Fleischman DA, Arfanakis K, Leurgans SE, et al. Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiol Aging. 2021;111:35-43doi: 10.1016/j.neurobiolaging.2021.11.003.
Fleischman, D. A., Arfanakis, K., Leurgans, S. E., Zhang, S., Poole, V. N., Han, S. D., Yu, L., Lamar, M., Kim, N., Bennett, D. A., & Barnes, L. L. (2022). Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiology of aging, 11135-43. https://doi.org/10.1016/j.neurobiolaging.2021.11.003
Fleischman, Debra A, et al. "Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia." Neurobiology of aging vol. 111 (2022): 35-43. doi: https://doi.org/10.1016/j.neurobiolaging.2021.11.003
Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Poole VN, Han SD, Yu L, Lamar M, Kim N, Bennett DA, Barnes LL. Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiol Aging. 2022 Mar;111:35-43. doi: 10.1016/j.neurobiolaging.2021.11.003. Epub 2021 Nov 20. PMID: 34963062.
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Showing 1 to 12 of 38 entries