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Showing 1 to 12 of 936 entries
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Evidence from gabbro of the Troodos ophiolite for lateral magma transport along a slow-spreading mid-ocean ridge.

Nature

Abelson M, Baer G, Agnon A.
PMID: 11343114
Nature. 2001 Jan 04;409(6816):72-5. doi: 10.1038/35051058.

The lateral flow of magma and ductile deformation of the lower crust along oceanic spreading axes has been thought to play a significant role in suppressing both mid-ocean ridge segmentation and variations in crustal thickness. Direct investigation of such...

Relation between ordering and shear thinning in colloidal suspensions.

Proceedings of the National Academy of Sciences of the United States of America

Xu X, Rice SA, Dinner AR.
PMID: 23431185
Proc Natl Acad Sci U S A. 2013 Mar 05;110(10):3771-6. doi: 10.1073/pnas.1301055110. Epub 2013 Feb 19.

Colloidal suspensions exhibit shear thinning and shear thickening. The most common interpretation of these phenomena identifies layering of the fluid perpendicular to the shear gradient as the driver for the observed behavior. However, studies of the particle configurations associated...

Lactase non-persistence as a determinant of milk avoidance and calcium intake in children and adolescents.

Journal of nutritional science

Almon R, Sjöström M, Nilsson TK.
PMID: 25191575
J Nutr Sci. 2013 Jul 24;2:e26. doi: 10.1017/jns.2013.11. eCollection 2013.

This study examines if lactase non-persistent (LNP) children and adolescents differ from those who are lactase persistent (LP) as regards milk avoidance and Ca intake. We also studied potential differences in anthropometric features related to obesity, and examined if...

Visual perceptual learning by operant conditioning training follows rules of contingency.

Visual cognition

Kim D, Seitz AR, Watanabe T.
PMID: 26028984
Vis cogn. 2015 Jan-Feb;23(1):147-160. doi: 10.1080/13506285.2015.1015663.

Visual perceptual learning (VPL) can occur as a result of a repetitive stimulus-reward pairing in the absence of any task. This suggests that rules that guide Conditioning, such as stimulus-reward contingency (e.g. that stimulus predicts the likelihood of reward),...

The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells.

Molecular therapy. Methods & clinical development

Romero Z, Campo-Fernandez B, Wherley J, Kaufman ML, Urbinati F, Cooper AR, Hoban MD, Baldwin KM, Lumaquin D, Wang X, Senadheera S, Hollis RP, Kohn DB.
PMID: 26029723
Mol Ther Methods Clin Dev. 2015 Apr 22;2:15012. doi: 10.1038/mtm.2015.12. eCollection 2015.

Lentiviral vectors designed for the treatment of the hemoglobinopathies require the inclusion of regulatory and strong enhancer elements to achieve sufficient expression of the β-globin transgene. Despite the inclusion of these elements, the efficacy of these vectors may be...

Microwave-promoted tin-free iminyl radical cyclization with TEMPO trapping: a practical synthesis of 2-acylpyrroles.

Organic letters

Cai Y, Jalan A, Kubosumi AR, Castle SL.
PMID: 25594391
Org Lett. 2015 Feb 06;17(3):488-91. doi: 10.1021/ol5035047. Epub 2015 Jan 16.

Microwave-promoted iminyl radical cyclizations can be terminated by trapping with TEMPO, affording functionalized adducts. The use of alkynes as radical acceptors delivers a range of 2-acylpyrroles in good yields. Toxic and hazardous reagents, which are frequently employed in radical...

Generalizable Learning: Practice Makes Perfect - But at What?.

Current biology : CB

Seitz AR.
PMID: 28324739
Curr Biol. 2017 Mar 20;27(6):R225-R227. doi: 10.1016/j.cub.2017.01.064.

Practising a task can produce learning that generalizes to other tasks. Measurement of such generalization is complicated by how generalization doesn't always manifest simply as better performance on the new task, but also in the form of faster learning.

Early release of tourniquet in total knee arthroplasty: Is it worthwhile?.

JPMA. The Journal of the Pakistan Medical Association

, Hafeez S, Amin MS, Ameen J, Adnan R.
PMID: 26878542
J Pak Med Assoc. 2015 Nov;65(11):S77-81.

OBJECTIVE: To compare the effects of duration and timing of tourniquet release on perioperative blood loss, transfusion requirement, duration of surgery, length of hospital stay and early complications in total knee arthroplastywith and without additional anti-fibrinolytic therapy.METHODS: The prospective...

External pelvic and vaginal irradiation vs. vaginal irradiation alone as postoperative therapy in women with early stage uterine serous carcinoma: Results of a National Cancer Database analysis.

Brachytherapy

Modh A, Burmeister C, Munkarah AR, Elshaikh MA.
PMID: 28511891
Brachytherapy. 2017 Jul - Aug;16(4):841-846. doi: 10.1016/j.brachy.2017.04.237. Epub 2017 May 13.

PURPOSE: Adjuvant treatment in early stage uterine serous carcinoma (USC) usually consists of chemotherapy with vaginal brachytherapy (VB), pelvic external beam radiation therapy (EBRT), or combination. We compared survival outcomes across these various radiation treatment modalities using the National...

Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions.

International journal for parasitology. Drugs and drug resistance

Kotze AC, Hunt PW, Skuce P, von Samson-Himmelstjerna G, Martin RJ, Sager H, Krücken J, Hodgkinson J, Lespine A, Jex AR, Gilleard JS, Beech RN, Wolstenholme AJ, Demeler J, Robertson AP, Charvet CL, Neveu C, Kaminsky R, Rufener L, Alberich M, Menez C, Prichard RK.
PMID: 25516826
Int J Parasitol Drugs Drug Resist. 2014 Aug 13;4(3):164-84. doi: 10.1016/j.ijpddr.2014.07.007. eCollection 2014 Dec.

Anthelmintic resistance has a great impact on livestock production systems worldwide, is an emerging concern in companion animal medicine, and represents a threat to our ongoing ability to control human soil-transmitted helminths. The Consortium for Anthelmintic Resistance and Susceptibility...

Upon the Shoulders of Giants: Open-Source Hardware and Software in Analytical Chemistry.

Analytical chemistry

Dryden MDM, Fobel R, Fobel C, Wheeler AR.
PMID: 28379683
Anal Chem. 2017 Apr 18;89(8):4330-4338. doi: 10.1021/acs.analchem.7b00485. Epub 2017 Apr 05.

Isaac Newton famously observed that "if I have seen further it is by standing on the shoulders of giants." We propose that this sentiment is a powerful motivation for the "open-source" movement in scientific research, in which creators provide...

The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma.

Journal for immunotherapy of cancer

Li M, Bolduc AR, Hoda MN, Gamble DN, Dolisca SB, Bolduc AK, Hoang K, Ashley C, McCall D, Rojiani AM, Maria BL, Rixe O, MacDonald TJ, Heeger PS, Mellor AL, Munn DH, Johnson TS.
PMID: 25054064
J Immunother Cancer. 2014 Jul 07;2:21. doi: 10.1186/2051-1426-2-21. eCollection 2014.

BACKGROUND: Indoleamine 2,3-dioxygenase (IDO) is an enzyme with immune-suppressive properties that is commonly exploited by tumors to evade immune destruction. Anti-tumor T cell responses can be initiated in solid tumors, but are immediately suppressed by compensatory upregulation of immunological...

Showing 1 to 12 of 936 entries