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Metabolic differences between Caucasian and African-American children and the relationship to type 2 diabetes mellitus

Minority STEM

Arslanian SA.
GSID: rJd2lDbPObYJ
SA Arslanian - Journal of pediatric endocrinology & metabolism …, 2002 - europepmc.org

… obesity and has been greatest among minority adolescents. Differences between African-… at risk and instituting lifestyle changes to reduce the risk and stem the development of DM. …

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Arslanian, S. A. (2002). Metabolic differences between Caucasian and African-American children and the relationship to type 2 diabetes mellitus. Journal of pediatric endocrinology & metabolism: JPEM, 15, 509-517.
Arslanian, Silva A. "Metabolic differences between Caucasian and African-American children and the relationship to type 2 diabetes mellitus." Journal of pediatric endocrinology & metabolism: JPEM 15 (2002): 509-517.
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The Diagnosis of Polycystic Ovary Syndrome during Adolescence.

Hormone research in paediatrics

Witchel SF, Oberfield S, Rosenfield RL, Codner E, Bonny A, Ibáñez L, Pena A, Horikawa R, Gomez-Lobo V, Joel D, Tfayli H, Arslanian S, Dabadghao P, Garcia Rudaz C, Lee PA.
PMID: 25833060
Horm Res Paediatr. 2015 Apr 01; doi: 10.1159/000375530. Epub 2015 Apr 01.

BACKGROUND/AIMS: The diagnostic criteria for polycystic ovary syndrome (PCOS) in adolescence are controversial, primarily because the diagnostic pathological features used in adult women may be normal pubertal physiological events. Hence, international pediatric and adolescent specialty societies have defined criteria...

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Witchel SF, Oberfield S, Rosenfield RL, et al. The Diagnosis of Polycystic Ovary Syndrome during Adolescence. Horm Res Paediatr. 2015;doi: 10.1159/000375530.
Witchel, S. F., Oberfield, S., Rosenfield, R. L., Codner, E., Bonny, A., Ibáñez, L., Pena, A., Horikawa, R., Gomez-Lobo, V., Joel, D., Tfayli, H., Arslanian, S., Dabadghao, P., Garcia Rudaz, C., & Lee, P. A. (2015). The Diagnosis of Polycystic Ovary Syndrome during Adolescence. Hormone research in paediatrics, . https://doi.org/10.1159/000375530
Witchel, Selma F, et al. "The Diagnosis of Polycystic Ovary Syndrome during Adolescence." Hormone research in paediatrics vol. (2015). doi: https://doi.org/10.1159/000375530
Witchel SF, Oberfield S, Rosenfield RL, Codner E, Bonny A, Ibáñez L, Pena A, Horikawa R, Gomez-Lobo V, Joel D, Tfayli H, Arslanian S, Dabadghao P, Garcia Rudaz C, Lee PA. The Diagnosis of Polycystic Ovary Syndrome during Adolescence. Horm Res Paediatr. 2015 Apr 01; doi: 10.1159/000375530. Epub 2015 Apr 01. PMID: 25833060.
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Insulin resistance of puberty in African-American children: lack of a compensatory increase in insulin secretion.

Pediatric diabetes

Saad RJ, Danadian K, Lewy V, Arslanian SA.
PMID: 15016168
Pediatr Diabetes. 2002 Mar;3(1):4-9. doi: 10.1034/j.1399-5448.2002.30102.x.

Type 2 diabetes has been increasing in children, mostly affecting minority populations at around the age of puberty. Despite a multitude of studies demonstrating pubertal insulin resistance/hyperinsulinemia in white children, data are almost non-existent in African-American children. The aim...

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Saad RJ, Danadian K, Lewy V, et al. Insulin resistance of puberty in African-American children: lack of a compensatory increase in insulin secretion. Pediatr Diabetes. 2002;3(1):4-9doi: 10.1034/j.1399-5448.2002.30102.x.
Saad, R. J., Danadian, K., Lewy, V., & Arslanian, S. A. (2002). Insulin resistance of puberty in African-American children: lack of a compensatory increase in insulin secretion. Pediatric diabetes, 3(1), 4-9. https://doi.org/10.1034/j.1399-5448.2002.30102.x
Saad, Rola J, et al. "Insulin resistance of puberty in African-American children: lack of a compensatory increase in insulin secretion." Pediatric diabetes vol. 3,1 (2002): 4-9. doi: https://doi.org/10.1034/j.1399-5448.2002.30102.x
Saad RJ, Danadian K, Lewy V, Arslanian SA. Insulin resistance of puberty in African-American children: lack of a compensatory increase in insulin secretion. Pediatr Diabetes. 2002 Mar;3(1):4-9. doi: 10.1034/j.1399-5448.2002.30102.x. PMID: 15016168.
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Parents' Readiness to Change Affects BMI Reduction Outcomes in Adolescents with Polycystic Ovary Syndrome.

Journal of obesity

Jakubowski KP, Black JJ, El Nokali NE, Belendiuk KA, Hannon TS, Arslanian SA, Rofey DL.
PMID: 22970350
J Obes. 2012;2012:298067. doi: 10.1155/2012/298067. Epub 2012 Aug 26.

Evidence supports the importance of parental involvement for youth's ability to manage weight. This study utilized the stages of change (SOC) model to assess readiness to change weight control behaviors as well as the predictive value of SOC in...

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Jakubowski KP, Black JJ, El Nokali NE, et al. Parents' Readiness to Change Affects BMI Reduction Outcomes in Adolescents with Polycystic Ovary Syndrome. J Obes. 2012;2012:298067doi: 10.1155/2012/298067.
Jakubowski, K. P., Black, J. J., El Nokali, N. E., Belendiuk, K. A., Hannon, T. S., Arslanian, S. A., & Rofey, D. L. (2012). Parents' Readiness to Change Affects BMI Reduction Outcomes in Adolescents with Polycystic Ovary Syndrome. Journal of obesity, 2012298067. https://doi.org/10.1155/2012/298067
Jakubowski, Karen P, et al. "Parents' Readiness to Change Affects BMI Reduction Outcomes in Adolescents with Polycystic Ovary Syndrome." Journal of obesity vol. 2012 (2012): 298067. doi: https://doi.org/10.1155/2012/298067
Jakubowski KP, Black JJ, El Nokali NE, Belendiuk KA, Hannon TS, Arslanian SA, Rofey DL. Parents' Readiness to Change Affects BMI Reduction Outcomes in Adolescents with Polycystic Ovary Syndrome. J Obes. 2012;2012:298067. doi: 10.1155/2012/298067. Epub 2012 Aug 26. PMID: 22970350; PMCID: PMC3433146.
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A surprising treatment response in a patient with rare isolated growth hormone deficiency, type IB.

Endocrinology, diabetes & metabolism case reports

Amar JY, Borden K, Watson E, Arslanian T.
PMID: 29147571
Endocrinol Diabetes Metab Case Rep. 2017 Nov 09;2017. doi: 10.1530/EDM-17-0107. eCollection 2017.

Isolated Growth Hormone Deficiency (IGHD) is a rare cause of short stature, treated with the standard regimen of subcutaneous synthetic growth hormone (GH). Patients typically achieve a maximum height velocity in the first year of treatment, which then tapers...

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Amar JY, Borden K, Watson E, et al. A surprising treatment response in a patient with rare isolated growth hormone deficiency, type IB. Endocrinol Diabetes Metab Case Rep. 2017;2017doi: 10.1530/EDM-17-0107.
Amar, J. Y., Borden, K., Watson, E., & Arslanian, T. (2017). A surprising treatment response in a patient with rare isolated growth hormone deficiency, type IB. Endocrinology, diabetes & metabolism case reports, 2017. https://doi.org/10.1530/EDM-17-0107
Amar, Jordan Yardain, et al. "A surprising treatment response in a patient with rare isolated growth hormone deficiency, type IB." Endocrinology, diabetes & metabolism case reports vol. 2017 (2017). doi: https://doi.org/10.1530/EDM-17-0107
Amar JY, Borden K, Watson E, Arslanian T. A surprising treatment response in a patient with rare isolated growth hormone deficiency, type IB. Endocrinol Diabetes Metab Case Rep. 2017 Nov 09;2017. doi: 10.1530/EDM-17-0107. eCollection 2017. PMID: 29147571; PMCID: PMC5682566.
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Age variation and sexual dimorphism in the sixteen diagnostic clusters of risk factors for the metabolic syndrome.

Zeitschrift fur Gesundheitswissenschaften = Journal of public health

Sun SS, Sabo R, Arslanian S, Wu R, Sabo C.
PMID: 23002329
Z Gesundh Wiss. 2012 Oct;20(5):487-497. doi: 10.1007/s10389-012-0490-2. Epub 2012 Jan 26.

OBJECTIVE: To document age- and sex-related differences in the 16 phenotypes of risk factors for the metabolic syndrome (MS) among adults in the Fels Longitudinal Study (FLS). METHODS: Data on risk factors for the MS were analyzed in 471...

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Sun SS, Sabo R, Arslanian S, et al. Age variation and sexual dimorphism in the sixteen diagnostic clusters of risk factors for the metabolic syndrome. Z Gesundh Wiss. 2012;20(5):487-497doi: 10.1007/s10389-012-0490-2.
Sun, S. S., Sabo, R., Arslanian, S., Wu, R., & Sabo, C. (2012). Age variation and sexual dimorphism in the sixteen diagnostic clusters of risk factors for the metabolic syndrome. Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 20(5), 487-497. https://doi.org/10.1007/s10389-012-0490-2
Sun, S S, et al. "Age variation and sexual dimorphism in the sixteen diagnostic clusters of risk factors for the metabolic syndrome." Zeitschrift fur Gesundheitswissenschaften = Journal of public health vol. 20,5 (2012): 487-497. doi: https://doi.org/10.1007/s10389-012-0490-2
Sun SS, Sabo R, Arslanian S, Wu R, Sabo C. Age variation and sexual dimorphism in the sixteen diagnostic clusters of risk factors for the metabolic syndrome. Z Gesundh Wiss. 2012 Oct;20(5):487-497. doi: 10.1007/s10389-012-0490-2. Epub 2012 Jan 26. PMID: 23002329; PMCID: PMC3443481.
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Morphometric Analysis of the Effects of Manuka Honey on Vasospastic Femoral Arteries in Rats: An Experimental Study.

Sisli Etfal Hastanesi tip bulteni

Tanrıverdi O, Yılmaz İ, Erdoğan U, Günaldı Ö, Güngör A, Adilay HU, Arslanhan A, Tuğcu B.
PMID: 32774089
Sisli Etfal Hastan Tip Bul. 2018 Dec 28;52(4):268-273. doi: 10.14744/SEMB.2018.35761. eCollection 2018.

OBJECTIVES: The aim of this study was to determine if Manuka honey, a potent anti-inflammatory and antioxidant agent, had any effect on the development of vasospasm in an experimental subarachnoidal hemorrhage model constructed in rat femoral arteries.METHODS: Twenty-four Wistar...

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Tanrıverdi O, Yılmaz İ, Erdoğan U, et al. Morphometric Analysis of the Effects of Manuka Honey on Vasospastic Femoral Arteries in Rats: An Experimental Study. Sisli Etfal Hastan Tip Bul. 2018;52(4):268-273doi: 10.14744/SEMB.2018.35761.
Tanrıverdi, O., Yılmaz, �. �., Erdoğan, U., Günaldı, �. �., Güngör, A., Adilay, H. U., Arslanhan, A., & Tuğcu, B. (2018). Morphometric Analysis of the Effects of Manuka Honey on Vasospastic Femoral Arteries in Rats: An Experimental Study. Sisli Etfal Hastanesi tip bulteni, 52(4), 268-273. https://doi.org/10.14744/SEMB.2018.35761
Tanrıverdi, Osman, et al. "Morphometric Analysis of the Effects of Manuka Honey on Vasospastic Femoral Arteries in Rats: An Experimental Study." Sisli Etfal Hastanesi tip bulteni vol. 52,4 (2018): 268-273. doi: https://doi.org/10.14744/SEMB.2018.35761
Tanrıverdi O, Yılmaz İ, Erdoğan U, Günaldı Ö, Güngör A, Adilay HU, Arslanhan A, Tuğcu B. Morphometric Analysis of the Effects of Manuka Honey on Vasospastic Femoral Arteries in Rats: An Experimental Study. Sisli Etfal Hastan Tip Bul. 2018 Dec 28;52(4):268-273. doi: 10.14744/SEMB.2018.35761. eCollection 2018. PMID: 32774089; PMCID: PMC7406554.
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β-cell impairment and clinically meaningful alterations in glycemia in obese youth across the glucose tolerance spectrum.

Metabolism: clinical and experimental

Kim JY, Tfayli H, Bacha F, Lee S, Gebara N, Arslanian S.
PMID: 32835760
Metabolism. 2020 Nov;112:154346. doi: 10.1016/j.metabol.2020.154346. Epub 2020 Aug 22.

BACKGROUND/AIMS: In obese youth, it is not clear what degree of β-cell impairment translates to glucose dysregulation commensurate with shifts from normal glucose tolerance (NGT) to impaired glucose tolerance (IGT) to type 2 diabetes. We aimed to investigate the...

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Kim JY, Tfayli H, Bacha F, et al. β-cell impairment and clinically meaningful alterations in glycemia in obese youth across the glucose tolerance spectrum. Metabolism. 2020;112:154346doi: 10.1016/j.metabol.2020.154346.
Kim, J. Y., Tfayli, H., Bacha, F., Lee, S., Gebara, N., & Arslanian, S. (2020). β-cell impairment and clinically meaningful alterations in glycemia in obese youth across the glucose tolerance spectrum. Metabolism: clinical and experimental, 112154346. https://doi.org/10.1016/j.metabol.2020.154346
Kim, Joon Young, et al. "β-cell impairment and clinically meaningful alterations in glycemia in obese youth across the glucose tolerance spectrum." Metabolism: clinical and experimental vol. 112 (2020): 154346. doi: https://doi.org/10.1016/j.metabol.2020.154346
Kim JY, Tfayli H, Bacha F, Lee S, Gebara N, Arslanian S. β-cell impairment and clinically meaningful alterations in glycemia in obese youth across the glucose tolerance spectrum. Metabolism. 2020 Nov;112:154346. doi: 10.1016/j.metabol.2020.154346. Epub 2020 Aug 22. PMID: 32835760; PMCID: PMC7897751.
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Separate and combined relationships for cardiorespiratory fitness and muscular strength with visceral fat and insulin sensitivity in adolescents with obesity.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme

Lee S, Pooni R, Arslanian S, Han M, Kuk JL.
PMID: 33625947
Appl Physiol Nutr Metab. 2021 Aug;46(8):945-951. doi: 10.1139/apnm-2020-0681. Epub 2021 Feb 24.

We examined the separate and combined associations for cardiorespiratory fitness (CRF) and muscular strength (MS) with total and regional fat, and insulin sensitivity (IS) in 204 adolescents (BMI ≥85th percentile, 12-18 years) at UPMC Children's Hospital of Pittsburgh. CRF...

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Lee S, Pooni R, Arslanian S, et al. Separate and combined relationships for cardiorespiratory fitness and muscular strength with visceral fat and insulin sensitivity in adolescents with obesity. Appl Physiol Nutr Metab. 2021;46(8):945-951doi: 10.1139/apnm-2020-0681.
Lee, S., Pooni, R., Arslanian, S., Han, M., & Kuk, J. L. (2021). Separate and combined relationships for cardiorespiratory fitness and muscular strength with visceral fat and insulin sensitivity in adolescents with obesity. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 46(8), 945-951. https://doi.org/10.1139/apnm-2020-0681
Lee, SoJung, et al. "Separate and combined relationships for cardiorespiratory fitness and muscular strength with visceral fat and insulin sensitivity in adolescents with obesity." Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme vol. 46,8 (2021): 945-951. doi: https://doi.org/10.1139/apnm-2020-0681
Lee S, Pooni R, Arslanian S, Han M, Kuk JL. Separate and combined relationships for cardiorespiratory fitness and muscular strength with visceral fat and insulin sensitivity in adolescents with obesity. Appl Physiol Nutr Metab. 2021 Aug;46(8):945-951. doi: 10.1139/apnm-2020-0681. Epub 2021 Feb 24. PMID: 33625947.
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Feasibility of using infrared thermal imaging to examine brown adipose tissue in infants aged 18 to 25 months.

Annals of human biology

Oyama S, Arslanian KJ, Levy SB, Ocobock CJ, Fidow UT, Naseri T, Hawley NL.
PMID: 34781801
Ann Hum Biol. 2021 Aug;48(5):374-381. doi: 10.1080/03014460.2021.1985607. Epub 2021 Nov 15.

BACKGROUND: Recent studies in adults indicate that cold-induced temperature change of supraclavicular skin corresponds with brown adipose tissue (BAT) thermogenesis.AIM: This study examined the feasibility of using thermography to assess temperature changes in infants aged 18-25 months after mild...

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Oyama S, Arslanian KJ, Levy SB, et al. Feasibility of using infrared thermal imaging to examine brown adipose tissue in infants aged 18 to 25 months. Ann Hum Biol. 2021;48(5):374-381doi: 10.1080/03014460.2021.1985607.
Oyama, S., Arslanian, K. J., Levy, S. B., Ocobock, C. J., Fidow, U. T., Naseri, T., & Hawley, N. L. (2021). Feasibility of using infrared thermal imaging to examine brown adipose tissue in infants aged 18 to 25 months. Annals of human biology, 48(5), 374-381. https://doi.org/10.1080/03014460.2021.1985607
Oyama, Sakurako, et al. "Feasibility of using infrared thermal imaging to examine brown adipose tissue in infants aged 18 to 25 months." Annals of human biology vol. 48,5 (2021): 374-381. doi: https://doi.org/10.1080/03014460.2021.1985607
Oyama S, Arslanian KJ, Levy SB, Ocobock CJ, Fidow UT, Naseri T, Hawley NL. Feasibility of using infrared thermal imaging to examine brown adipose tissue in infants aged 18 to 25 months. Ann Hum Biol. 2021 Aug;48(5):374-381. doi: 10.1080/03014460.2021.1985607. Epub 2021 Nov 15. PMID: 34781801.
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Longitudinal changes in vascular stiffness and heart rate variability among young adults with youth-onset type 2 diabetes: results from the follow-up observational treatment options for type 2 diabetes in adolescents and youth (TODAY) study.

Acta diabetologica

, Shah AS, El Ghormli L, Gidding SS, Hughan KS, Levitt Katz LE, Koren D, Tryggestad JB, Bacha F, Braffett BH, Arslanian S, Urbina EM.
PMID: 34542729
Acta Diabetol. 2021 Sep 20; doi: 10.1007/s00592-021-01796-6. Epub 2021 Sep 20.

AIMS: (1) To describe changes in arterial stiffness and heart rate variability (HRV) over a 5-year interval, (2) examine changes by sex and race-ethnicity, and (3) evaluate the risk factors associated with the longitudinal changes in arterial stiffness and...

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, Shah AS, El Ghormli L, et al. Longitudinal changes in vascular stiffness and heart rate variability among young adults with youth-onset type 2 diabetes: results from the follow-up observational treatment options for type 2 diabetes in adolescents and youth (TODAY) study. Acta Diabetol. 2021;doi: 10.1007/s00592-021-01796-6.
, Shah, A. S., El Ghormli, L., Gidding, S. S., Hughan, K. S., Levitt Katz, L. E., Koren, D., Tryggestad, J. B., Bacha, F., Braffett, B. H., Arslanian, S., & Urbina, E. M. (2021). Longitudinal changes in vascular stiffness and heart rate variability among young adults with youth-onset type 2 diabetes: results from the follow-up observational treatment options for type 2 diabetes in adolescents and youth (TODAY) study. Acta diabetologica, . https://doi.org/10.1007/s00592-021-01796-6
, et al. "Longitudinal changes in vascular stiffness and heart rate variability among young adults with youth-onset type 2 diabetes: results from the follow-up observational treatment options for type 2 diabetes in adolescents and youth (TODAY) study." Acta diabetologica vol. (2021). doi: https://doi.org/10.1007/s00592-021-01796-6
, Shah AS, El Ghormli L, Gidding SS, Hughan KS, Levitt Katz LE, Koren D, Tryggestad JB, Bacha F, Braffett BH, Arslanian S, Urbina EM. Longitudinal changes in vascular stiffness and heart rate variability among young adults with youth-onset type 2 diabetes: results from the follow-up observational treatment options for type 2 diabetes in adolescents and youth (TODAY) study. Acta Diabetol. 2021 Sep 20; doi: 10.1007/s00592-021-01796-6. Epub 2021 Sep 20. PMID: 34542729.
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On the nature of the interaction of copper hydride and halide with substituted ethylene and acetylene.

Journal of molecular modeling

Arslancan S, Herrera B, Lamsabhi AM.
PMID: 32088811
J Mol Model. 2020 Feb 22;26(3):61. doi: 10.1007/s00894-020-4320-0.

The association of Cu-X (X = -H, -Cl, and -F) with H

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Arslancan S, Herrera B, Lamsabhi AM. On the nature of the interaction of copper hydride and halide with substituted ethylene and acetylene. J Mol Model. 2020;26(3):61doi: 10.1007/s00894-020-4320-0.
Arslancan, S., Herrera, B., & Lamsabhi, A. M. (2020). On the nature of the interaction of copper hydride and halide with substituted ethylene and acetylene. Journal of molecular modeling, 26(3), 61. https://doi.org/10.1007/s00894-020-4320-0
Arslancan, Serra, et al. "On the nature of the interaction of copper hydride and halide with substituted ethylene and acetylene." Journal of molecular modeling vol. 26,3 (2020): 61. doi: https://doi.org/10.1007/s00894-020-4320-0
Arslancan S, Herrera B, Lamsabhi AM. On the nature of the interaction of copper hydride and halide with substituted ethylene and acetylene. J Mol Model. 2020 Feb 22;26(3):61. doi: 10.1007/s00894-020-4320-0. PMID: 32088811.
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