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Showing 1 to 12 of 63 entries
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Corrigendum to "Epicutaneous immunization with phosphorylcholine conjugated to bovine serum albumin (PC-BSA) and TLR9 ligand CpG alleviates pneumococcal pneumonia in mice" [Pharmacol. Rep. 66 (2014) 570-575].

Pharmacological reports : PR

Majewska-Szczepanik M, Yamamoto N, Askenase PW, Szczepanik M.
PMID: 28365257
Pharmacol Rep. 2017 Jun;69(3):584. doi: 10.1016/j.pharep.2017.01.014. Epub 2017 Mar 29.

No abstract available.

Preliminary test of the LFA rapid evaluation of activity in lupus (LFA-REAL): an efficient outcome measure correlates with validated instruments.

Lupus science & medicine

Askanase A, Li X, Pong A, Shum K, Kamp S, Carthen F, Aberle T, Hanrahan L, Daly P, Giles J, Merrill JT.
PMID: 25861457
Lupus Sci Med. 2015 Mar 04;2(1):e000075. doi: 10.1136/lupus-2014-000075. eCollection 2015.

OBJECTIVE: Current disease activity measures for systemic lupus erythematosus (SLE) are difficult to score or interpret and problematic for use in clinical practice. Lupus Foundation of America (LFA)-Rapid Evaluation of Activity in Lupus (REAL) is a pilot application composed...

Myocarditis in systemic lupus erythematosus diagnosed by .

Lupus science & medicine

Perel-Winkler A, Bokhari S, Perez-Recio T, Zartoshti A, Askanase A, Geraldino-Pardilla L.
PMID: 30094040
Lupus Sci Med. 2018 Jul 12;5(1):e000265. doi: 10.1136/lupus-2018-000265. eCollection 2018.

OBJECTIVES: Cardiovascular diseaseand heart failure (CHF) are leading causes of death in systemic lupus erythematosus (SLE). The underlying mechanisms for increased CHF in SLE are unclear but myocardial inflammation and lupus myocarditis (LM) may play a role. We propose...

The Rise and Fall of Hydroxychloroquine with the COVID-19 Pandemic: Narrative Review of Selected Data.

Rheumatology and therapy

Tang W, Khalili L, Giles J, Gartshteyn Y, Kapoor T, Guo C, Chen T, Theodore D, Askanase A.
PMID: 34028704
Rheumatol Ther. 2021 Jun;8(2):681-691. doi: 10.1007/s40744-021-00315-x. Epub 2021 May 24.

Since the first outbreak of Coronavirus Disease-2019 (COVID-19) in January 2020, the medical community has been pursuing effective countermeasures. Early in the pandemic, several small clinical and in vitro studies from France and China reported on the efficacy of...

Lower vitamin D is associated with metabolic syndrome and insulin resistance in systemic lupus: data from an international inception cohort.

Rheumatology (Oxford, England)

Chew C, Reynolds JA, Lertratanakul A, Wu P, Urowitz M, Gladman DD, Fortin PR, Bae SC, Gordon C, Clarke AE, Bernatsky S, Hanly JG, Isenberg D, Rahman A, Sanchez-Guerrero J, Romero-Diaz J, Merrill J, Wallace D, Ginzler E, Khamashta M, Nived O, Jönsen A, Steinsson K, Manzi S, Kalunian K, Dooley MA, Petri M, Aranow C, van Vollenhoven R, Stoll T, Alarcón GS, Lim SS, Ruiz-Irastorza G, Peschken CA, Askanase AD, Kamen DL, İnanç M, Ramsey-Goldman R, Bruce IN.
PMID: 33555325
Rheumatology (Oxford). 2021 Oct 02;60(10):4737-4747. doi: 10.1093/rheumatology/keab090.

OBJECTIVES: Vitamin D (25(OH)D) deficiency and metabolic syndrome (MetS) may both contribute to increased cardiovascular risk in SLE. We aimed to examine the association of demographic factors, SLE phenotype, therapy and vitamin D levels with MetS and insulin resistance.METHODS:...

Cell-bound complement activation products in systemic lupus erythematosus: comparison with anti-double-stranded DNA and standard complement measurements.

Lupus science & medicine

Putterman C, Furie R, Ramsey-Goldman R, Askanase A, Buyon J, Kalunian K, Chatham WW, Massarotti E, Kirou K, Jordan N, Blanco I, Weinstein A, Chitkara P, Manzi S, Ahearn J, O'Malley T, Conklin J, Ibarra C, Barken D, Dervieux T.
PMID: 25396070
Lupus Sci Med. 2014 Oct 01;1(1):e000056. doi: 10.1136/lupus-2014-000056. eCollection 2014.

OBJECTIVE: To compare the performance characteristics of cell-bound complement (C4d) activation products (CBCAPS) on erythrocyte (EC4d) and B cells (BC4d) with antibodies to double-stranded DNA (anti-dsDNA) and complement C3 and C4 in systemic lupus erythematosus (SLE).METHODS: The study enrolled...

Adrenocorticotropic hormone gel in the treatment of systemic lupus erythematosus: A retrospective study of patients.

F1000Research

Li X, Golubovsky J, Hui-Yuen J, Shah U, Olech E, Lomeo R, Singh V, Busch H, Strandberg MJ, Strandberg K, Horowitz L, Askanase A.
PMID: 27158444
F1000Res. 2015 Oct 23;4:1103. doi: 10.12688/f1000research.7192.1. eCollection 2015.

OBJECTIVES: Acthar Gel is a long-acting formulation of adrenocorticotropic hormone (ACTH) with anti-inflammatory effects thought to be mediated in part through melanocortin receptor activation. This study was initiated to understand the role of Acthar Gel in SLE treatment in...

Lupus community panel proposals for optimising clinical trials: 2018.

Lupus science & medicine

Merrill JT, Manzi S, Aranow C, Askanase A, Bruce I, Chakravarty E, Chong B, Costenbader K, Dall'Era M, Ginzler E, Hanrahan L, Kalunian K, Merola J, Raymond S, Rovin B, Saxena A, Werth VP.
PMID: 29657738
Lupus Sci Med. 2018 Mar 23;5(1):e000258. doi: 10.1136/lupus-2018-000258. eCollection 2018.

Formidable impediments stand in the way of treatment development for lupus. These include the unwieldy size of current trials, international competition for scarce patients, complex outcome measures and a poor understanding of these outcomes in the world at large....

Flares after hydroxychloroquine reduction or discontinuation: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort.

Annals of the rheumatic diseases

Almeida-Brasil CC, Hanly JG, Urowitz M, Clarke AE, Ruiz-Irastorza G, Gordon C, Ramsey-Goldman R, Petri M, Ginzler EM, Wallace DJ, Bae SC, Romero-Diaz J, Dooley MA, Peschken C, Isenberg D, Rahman A, Manzi S, Jacobsen S, Lim S, van Vollenhoven RF, Nived O, Jönsen A, Kamen DL, Aranow C, Sanchez-Guerrero J, Gladman DD, Fortin PR, Alarcón GS, Merrill JT, Kalunian K, Ramos-Casals M, Steinsson K, Zoma A, Askanase A, Khamashta MA, Bruce IN, Inanc M, Abrahamowicz M, Bernatsky S.
PMID: 34911705
Ann Rheum Dis. 2021 Dec 15; doi: 10.1136/annrheumdis-2021-221295. Epub 2021 Dec 15.

OBJECTIVES: To evaluate systemic lupus erythematosus (SLE) flares following hydroxychloroquine (HCQ) reduction or discontinuation versus HCQ maintenance.METHODS: We analysed prospective data from the Systemic Lupus International Collaborating Clinics (SLICC) cohort, enrolled from 33 sites within 15 months of SLE...

Prediction of hospitalizations in systemic lupus erythematosus using the Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI).

Arthritis care & research

Legge A, Kirkland S, Rockwood K, Andreou P, Bae SC, Gordon C, Romero-Diaz J, Sanchez-Guerrero J, Wallace DJ, Bernatsky S, Clarke AE, Merrill JT, Ginzler EM, Fortin PR, Gladman DD, Urowitz MB, Bruce IN, Isenberg DA, Rahman A, Alarcón GS, Petri M, Khamashta MA, Dooley MA, Ramsey-Goldman R, Manzi S, Zoma AA, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, van Vollenhoven RF, Jonsen A, Nived O, Ramos-Casals M, Kamen DL, Kalunian KC, Jacobsen S, Peschken CA, Askanase A, Hanly JG.
PMID: 33152181
Arthritis Care Res (Hoboken). 2020 Nov 05; doi: 10.1002/acr.24504. Epub 2020 Nov 05.

OBJECTIVE: The Systemic Lupus International Collaborating Clinics (SLICC) frailty index (FI) predicts mortality and damage accrual in SLE, but its association with hospitalizations has not been described. We estimated the association of baseline SLICC-FI values with future hospitalizations in...

Response to: 'Phsician's global assessment is often useful in SLE, but not always: the case of clinical remission' by Zen .

Annals of the rheumatic diseases

Askanase A, Oon S, Huq M, Calderone A, Morand EF, Nikpour M, Aranow C.
PMID: 32434819
Ann Rheum Dis. 2020 May 20; doi: 10.1136/annrheumdis-2020-217687. Epub 2020 May 20.

No abstract available.

Repository Corticotropin Injection for Persistently Active Systemic Lupus Erythematosus: Results from a Phase 4, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial.

Rheumatology and therapy

Askanase AD, Zhao E, Zhu J, Bilyk R, Furie RA.
PMID: 32996096
Rheumatol Ther. 2020 Dec;7(4):893-908. doi: 10.1007/s40744-020-00236-1. Epub 2020 Sep 29.

INTRODUCTION: We assessed the efficacy and safety of repository corticotropin injection (RCI; ActharMETHODS: This multicenter, double-blind, randomized, placebo-controlled study enrolled patients ≥ 18 years with active SLE and moderate to severe rash and/or arthritis despite stable glucocorticoid doses (7.5-30...

Showing 1 to 12 of 63 entries