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Showing 1 to 8 of 8 entries
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Erratum to 'Molecular horizons of cancer therapeutics. 11th pezcoller Symposium'.

Biochimica et biophysica acta

Avantaggiati ML.
PMID: 10967426
Biochim Biophys Acta. 2000 Jul 31;1471(1):R15. doi: 10.1016/s0304-419x(00)00017-2.

No abstract available.

Regulation of Chemosensitivity in Human Medulloblastoma Cells by p53 and the PI3 Kinase Signaling Pathway.

Molecular cancer research : MCR

Naeem A, Harish V, Coste S, Parasido EM, Choudhry MU, Kromer LF, Ihemelandu C, Petricoin EF, Pierobon M, Noon MS, Yenugonda VM, Avantaggiati M, Kupfer GM, Fricke S, Rodriguez O, Albanese C.
PMID: 34635507
Mol Cancer Res. 2022 Jan;20(1):114-126. doi: 10.1158/1541-7786.MCR-21-0277. Epub 2021 Oct 11.

In medulloblastoma, p53 expression has been associated with chemoresistance and radiation resistance and with poor long-term outcomes in the

Arginase Pathway Markers of Immune-Microenvironment in Thymic Epithelial Tumors and Small Cell Lung Cancer.

Clinical lung cancer

Umemura S, Chen V, Chahine JJ, Kallakury B, Zhao X, Lee H, Avantaggiati ML, He Y, Wang C, Giaccone G.
PMID: 34393062
Clin Lung Cancer. 2021 Jul 20; doi: 10.1016/j.cllc.2021.07.006. Epub 2021 Jul 20.

BACKGROUND: Key regulators of antitumor immunity such as arginase-1 and the adenosine pathway may have an important role in modulating the effect of immunotherapy. Here, we investigated the expression profile of these immune-related biomarkers in thymic epithelial tumors (TETs)...

Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity.

Frontiers in oncology

Schlottmann S, Erkizan HV, Barber-Rotenberg JS, Knights C, Cheema A, Uren A, Avantaggiati ML, Toretsky JA.
PMID: 22973553
Front Oncol. 2012 Sep 07;2:107. doi: 10.3389/fonc.2012.00107. eCollection 2012.

Ewing Sarcoma (ES) is associated with a balanced chromosomal translocation that in most cases leads to the expression of the oncogenic fusion protein and transcription factor EWS-FLI1. EWS-FLI1 has been shown to be crucial for ES cell survival and...

Expanding the Clinical Spectrum of Mitochondrial Citrate Carrier (SLC25A1) Deficiency: Facial Dysmorphism in Siblings with Epileptic Encephalopathy and Combined D,L-2-Hydroxyglutaric Aciduria.

JIMD reports

Prasun P, Young S, Salomons G, Werneke A, Jiang YH, Struys E, Paige M, Avantaggiati ML, McDonald M.
PMID: 25614306
JIMD Rep. 2015;19:111-5. doi: 10.1007/8904_2014_378. Epub 2015 Jan 23.

Recessive mutations in SLC25A1 encoding mitochondrial citrate carrier cause a rare inherited metabolic disorder, combined D,L-2-hydroxyglutaric aciduria (D,L-2-HGA), characterized by epileptic encephalopathy, respiratory insufficiency, developmental arrest and early death. Here, we describe two siblings compound heterozygotes for null/missense SLC25A1...

Regulation of Chemosensitivity in Human Medulloblastoma Cells by p53 and the PI3 Kinase Signaling Pathway.

Molecular cancer research : MCR

Naeem A, Harish V, Coste S, Parasido EM, Choudhry MU, Kromer LF, Ihemelandu C, Petricoin EF, Pierobon M, Noon MS, Yenugonda VM, Avantaggiati M, Kupfer GM, Fricke S, Rodriguez O, Albanese C.
PMID: 34635507
Mol Cancer Res. 2021 Oct 11; doi: 10.1158/1541-7786.MCR-21-0277. Epub 2021 Oct 11.

In medulloblastoma, p53 expression has been associated with chemoresistance and radiation resistance and with poor long-term outcomes in the

Regulation of Chemosensitivity in Human Medulloblastoma Cells by p53 and the PI3 Kinase Signaling Pathway.

Molecular cancer research : MCR

Naeem A, Harish V, Coste S, Parasido EM, Choudhry MU, Kromer LF, Ihemelandu C, Petricoin EF, Pierobon M, Noon MS, Yenugonda VM, Avantaggiati M, Kupfer GM, Fricke S, Rodriguez O, Albanese C.
PMID: 34635507
Mol Cancer Res. 2022 Jan;20(1):114-126. doi: 10.1158/1541-7786.MCR-21-0277. Epub 2021 Oct 11.

In medulloblastoma, p53 expression has been associated with chemoresistance and radiation resistance and with poor long-term outcomes in the

Characterization of the effects of defined, multidimensional culture conditions on conditionally reprogrammed primary human prostate cells.

Oncotarget

Tricoli L, Naeem A, Parasido E, Mikhaiel JP, Choudhry MU, Berry DL, Abdelgawad IA, Lee RJ, Feldman AS, Ihemelandu C, Avantaggiati M, Kumar D, Byers S, Gallagher R, Wulfkuhle J, Petricoin E, Rodriguez O, Albanese C.
PMID: 29416764
Oncotarget. 2017 Dec 18;9(2):2193-2207. doi: 10.18632/oncotarget.23363. eCollection 2018 Jan 05.

The inability to propagate human prostate epithelial cells indefinitely has historically presented a serious impediment to prostate cancer research. The conditionally reprogrammed cell (CRC) approach uses the combination of irradiated J2 mouse fibroblasts and a Rho kinase inhibitor such...

Showing 1 to 8 of 8 entries