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Showing 1 to 12 of 214 entries
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Large Scale 7436-bp Deletions in Human Sperm Mitochondrial DNA with Spermatozoa Dysfunction and Male Infertility.

Journal of clinical and diagnostic research : JCDR

Ambulkar PS, Waghmare JE, Chaudhari AR, Wankhede VR, Tarnekar AM, Shende MR, Pal AK.
PMID: 28050401
J Clin Diagn Res. 2016 Nov;10(11):GC09-GC12. doi: 10.7860/JCDR/2016/22412.8843. Epub 2016 Nov 01.

INTRODUCTION: Mitochondria and mitochondrial DNA are essential to sperm motility and fertility. It controls growth, development and differentiation through oxidation energy supply. Mitochondrial (mtDNA) deletions or mutation are frequently attributed to defects of sperm motility and finally these deletions...

Knowledge of pregnant women on mother-to-child transmission of HIV, its prevention, and associated factors in Assosa town, Northwest Ethiopia.

HIV/AIDS (Auckland, N.Z.)

Abtew S, Awoke W, Asrat A.
PMID: 27217801
HIV AIDS (Auckl). 2016 May 05;8:101-7. doi: 10.2147/HIV.S100301. eCollection 2016.

INTRODUCTION: HIV/AIDS is a leading cause of death of children in sub-Saharan African countries. Almost all HIV-positive children acquire infection through mother-to-child transmission (MTCT) of HIV. Successful intervention toward prevention of mother-to-child transmission (PMTCT) and achieving the goal of...

Total erythrocyte membrane cholesterol: a marker of plaque instability?.

Nature clinical practice. Cardiovascular medicine

Finn AV, Gold HK.
PMID: 17768403
Nat Clin Pract Cardiovasc Med. 2007 Dec;4(12):646-7. doi: 10.1038/ncpcardio0986. Epub 2007 Sep 04.

No abstract available.

Do vulnerable and ruptured plaques hide in heavily calcified arteries?.

Atherosclerosis

Otsuka F, Finn AV, Virmani R.
PMID: 23375681
Atherosclerosis. 2013 Jul;229(1):34-7. doi: 10.1016/j.atherosclerosis.2012.12.032. Epub 2013 Jan 09.

No abstract available.

Novel bivalent ligands for D2/D3 dopamine receptors: Significant co-operative gain in D2 affinity and potency.

ACS medicinal chemistry letters

Gogoi S, Biswas S, Modi G, Antonio T, Reith ME, Dutta AK.
PMID: 23275802
ACS Med Chem Lett. 2012 Oct 26;3(12):991-996. doi: 10.1021/ml3002117.

This report describes development of a series of novel bivalent molecules with a pharmacophore derived from the D2/D3 agonist 5-OH-DPAT. Spacer length in the bivalent compounds had a pronounced influence on affinity for D2 receptors. A 23-fold increase of...

HIV-Positive Status Disclosure and Associated Factors among Children in North Gondar, Northwest Ethiopia.

ISRN AIDS

Negese D, Addis K, Awoke A, Birhanu Z, Muluye D, Yifru S, Megabiaw B.
PMID: 24052875
ISRN AIDS. 2012 Dec 13;2012:485720. doi: 10.5402/2012/485720. eCollection 2012.

Introduction. Clinical reports have indicated positive outcomes associated with disclosure of HIV-positive status in children. This study assessed the level and associated factors of HIV-positive status disclosure to HIV-infected children in northwest Ethiopia. Methods. Institution-based cross-sectional study was conducted...

Understanding the Structural Requirements of Hybrid (S)-6-((2-(4-Phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol and its Analogs as D2/D3 Receptor Ligands: A Three-Dimensional Quantitative Structure-Activity Relationship (3D QSAR) Investigation.

MedChemComm

Modi G, Sharma H, Kharkar PS, Dutta AK.
PMID: 25221669
Medchemcomm. 2014 Sep 01;5(9):1384-1399. doi: 10.1039/C4MD00159A.

To gain insights into the structural requirements for dopamine D2 and D3 agonists in the treatment of Parkinson's disease (PD) and to elucidate the basis of selectivity for D3 over D2 (D2/D3), 3D quantitative structure-activity relationship (3D QSAR) investigations...

Antenatal Practices Ineffective at Prevention of Plasmodium falciparum Malaria during Pregnancy in a Sub-Saharan Africa Region, Nigeria.

Tropical medicine and infectious disease

Aguzie ION, Ivoke N, Onyishi GC, Okoye IC.
PMID: 30270874
Trop Med Infect Dis. 2017 Jun 12;2(2). doi: 10.3390/tropicalmed2020015.

Pregnancy-associated malaria (PAM) is a major public health concern constituting a serious risk to the pregnant woman, her foetus, and newborn. Management of cases and prevention rely partly on effective and efficient antenatal services. This study examined the effectiveness...

Nurses Practice of Hand Hygiene in Hiwot Fana Specialized University Hospital, Harari Regional State, Eastern Ethiopia: Observational Study.

Nursing research and practice

Awoke N, Geda B, Arba A, Tekalign T, Paulos K.
PMID: 29850239
Nurs Res Pract. 2018 Apr 16;2018:2654947. doi: 10.1155/2018/2654947. eCollection 2018.

BACKGROUND: Nurses, who are the majority, can contaminate their hands with different types of microorganism during "clean" activities (e.g., lifting a patient; taking a patient's pulse, blood pressure, or oral temperature; or touching a patient's hand, shoulder, or groin)....

Chemical, mineral composition, and sensory acceptability of cocoyam-based recipes enriched with cowpea flour.

Food science & nutrition

Olayiwola I, Folaranmi F, Adebowale AA, Oluseye O, Ajoke S, Wasiu A.
PMID: 29387351
Food Sci Nutr. 2013 Mar 06;1(3):228-234. doi: 10.1002/fsn3.30. eCollection 2013 May.

The study was conducted to improve cocoyam-based recipes (steamed cocoyam paste [

Suicide ideation and attempts among people with epilepsy in Addis Ababa, Ethiopia.

Annals of general psychiatry

Haile K, Awoke T, Ayano G, Ayano G, Tareke M, Abate A, Nega M.
PMID: 29410698
Ann Gen Psychiatry. 2018 Jan 24;17:4. doi: 10.1186/s12991-018-0174-6. eCollection 2018.

BACKGROUND: Suicidal ideation and attempts are more frequent in people with epilepsy than in general population and suicide attempt increases the chance of later completed suicide. The aim of this study was to assess the prevalence and associated factors...

Understanding the unique experiences, perspectives and sexual and reproductive health needs of very young adolescents: Somali refugees in Ethiopia.

Conflict and health

Ortiz-Echevarria L, Greeley M, Bawoke T, Zimmerman L, Robinson C, Schlecht J.
PMID: 29163667
Confl Health. 2017 Nov 14;11:26. doi: 10.1186/s13031-017-0129-6. eCollection 2017.

BACKGROUND: Kobe Refugee camp hosts roughly 39,000 refugees displaced from Somalia during the 2011-2012 Horn of Africa Crisis. Sexual and reproductive health, as with the greater issues of health and well-being for adolescents displaced from this crisis remain largely...

Showing 1 to 12 of 214 entries