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Antioxidant Tocols as Radiation Countermeasures (Challenges to be Addressed to Use Tocols as Radiation Countermeasures in Humans).

Antioxidants (Basel, Switzerland)

Nukala U, Thakkar S, Krager KJ, Breen PJ, Compadre CM, Aykin-Burns N.
PMID: 29473853
Antioxidants (Basel). 2018 Feb 23;7(2). doi: 10.3390/antiox7020033.

Radiation countermeasures fall under three categories, radiation protectors, radiation mitigators, and radiation therapeutics. Radiation protectors are agents that are administered before radiation exposure to protect from radiation-induced injuries by numerous mechanisms, including scavenging free radicals that are generated by...

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Nukala U, Thakkar S, Krager KJ, et al. Antioxidant Tocols as Radiation Countermeasures (Challenges to be Addressed to Use Tocols as Radiation Countermeasures in Humans). Antioxidants (Basel). 2018;7(2)doi: 10.3390/antiox7020033.
Nukala, U., Thakkar, S., Krager, K. J., Breen, P. J., Compadre, C. M., & Aykin-Burns, N. (2018). Antioxidant Tocols as Radiation Countermeasures (Challenges to be Addressed to Use Tocols as Radiation Countermeasures in Humans). Antioxidants (Basel, Switzerland), 7(2), . https://doi.org/10.3390/antiox7020033
Nukala, Ujwani, et al. "Antioxidant Tocols as Radiation Countermeasures (Challenges to be Addressed to Use Tocols as Radiation Countermeasures in Humans)." Antioxidants (Basel, Switzerland) vol. 7,2 (2018). doi: https://doi.org/10.3390/antiox7020033
Nukala U, Thakkar S, Krager KJ, Breen PJ, Compadre CM, Aykin-Burns N. Antioxidant Tocols as Radiation Countermeasures (Challenges to be Addressed to Use Tocols as Radiation Countermeasures in Humans). Antioxidants (Basel). 2018 Feb 23;7(2). doi: 10.3390/antiox7020033. PMID: 29473853; PMCID: PMC5836023.
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Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice.

International journal of molecular sciences

Kim HN, Richardson KK, Krager KJ, Ling W, Simmons P, Allen AR, Aykin-Burns N.
PMID: 34769141
Int J Mol Sci. 2021 Oct 28;22(21). doi: 10.3390/ijms222111711.

Space is a high-stress environment. One major risk factor for the astronauts when they leave the Earth's magnetic field is exposure to ionizing radiation from galactic cosmic rays (GCR). Several adverse changes occur in mammalian anatomy and physiology in...

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Kim HN, Richardson KK, Krager KJ, et al. Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice. Int J Mol Sci. 2021;22(21)doi: 10.3390/ijms222111711.
Kim, H. N., Richardson, K. K., Krager, K. J., Ling, W., Simmons, P., Allen, A. R., & Aykin-Burns, N. (2021). Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice. International journal of molecular sciences, 22(21), . https://doi.org/10.3390/ijms222111711
Kim, Ha-Neui, et al. "Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice." International journal of molecular sciences vol. 22,21 (2021). doi: https://doi.org/10.3390/ijms222111711
Kim HN, Richardson KK, Krager KJ, Ling W, Simmons P, Allen AR, Aykin-Burns N. Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice. Int J Mol Sci. 2021 Oct 28;22(21). doi: 10.3390/ijms222111711. PMID: 34769141; PMCID: PMC8583929.
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Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency.

JCI insight

Ling W, Krager K, Richardson KK, Warren AD, Ponte F, Aykin-Burns N, Manolagas SC, Almeida M, Kim HN.
PMID: 33878033
JCI Insight. 2021 May 24;6(10). doi: 10.1172/jci.insight.146728.

Altered mitochondria activity in osteoblasts and osteoclasts has been implicated in the loss of bone mass associated with aging and estrogen deficiency - the 2 most common causes of osteoporosis. However, the mechanisms that control mitochondrial metabolism in bone...

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Ling W, Krager K, Richardson KK, et al. Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency. JCI Insight. 2021;6(10)doi: 10.1172/jci.insight.146728.
Ling, W., Krager, K., Richardson, K. K., Warren, A. D., Ponte, F., Aykin-Burns, N., Manolagas, S. C., Almeida, M., & Kim, H. N. (2021). Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency. JCI insight, 6(10), . https://doi.org/10.1172/jci.insight.146728
Ling, Wen, et al. "Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency." JCI insight vol. 6,10 (2021). doi: https://doi.org/10.1172/jci.insight.146728
Ling W, Krager K, Richardson KK, Warren AD, Ponte F, Aykin-Burns N, Manolagas SC, Almeida M, Kim HN. Mitochondrial Sirt3 contributes to the bone loss caused by aging or estrogen deficiency. JCI Insight. 2021 May 24;6(10). doi: 10.1172/jci.insight.146728. PMID: 33878033; PMCID: PMC8262324.
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PCB11 Metabolite, 3,3'-Dichlorobiphenyl-4-ol, Exposure Alters the Expression of Genes Governing Fatty Acid Metabolism in the Absence of Functional Sirtuin 3: Examining the Contribution of MnSOD.

Antioxidants (Basel, Switzerland)

Alam S, Carter GS, Krager KJ, Li X, Lehmler HJ, Aykin-Burns N.
PMID: 30223548
Antioxidants (Basel). 2018 Sep 15;7(9). doi: 10.3390/antiox7090121.

Although the production of polychlorinated biphenyls (PCBs) is prohibited, the inadvertent production of certain lower-chlorinated PCB congeners still threatens human health. We and others have identified 3,3'-dichlorobiphenyl (PCB11) and its metabolite, 3,3'-dichlorobiphenyl-4-ol (4OH-PCB11), in human blood, and there is...

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Alam S, Carter GS, Krager KJ, et al. PCB11 Metabolite, 3,3'-Dichlorobiphenyl-4-ol, Exposure Alters the Expression of Genes Governing Fatty Acid Metabolism in the Absence of Functional Sirtuin 3: Examining the Contribution of MnSOD. Antioxidants (Basel). 2018;7(9)doi: 10.3390/antiox7090121.
Alam, S., Carter, G. S., Krager, K. J., Li, X., Lehmler, H. J., & Aykin-Burns, N. (2018). PCB11 Metabolite, 3,3'-Dichlorobiphenyl-4-ol, Exposure Alters the Expression of Genes Governing Fatty Acid Metabolism in the Absence of Functional Sirtuin 3: Examining the Contribution of MnSOD. Antioxidants (Basel, Switzerland), 7(9), . https://doi.org/10.3390/antiox7090121
Alam, Sinthia, et al. "PCB11 Metabolite, 3,3'-Dichlorobiphenyl-4-ol, Exposure Alters the Expression of Genes Governing Fatty Acid Metabolism in the Absence of Functional Sirtuin 3: Examining the Contribution of MnSOD." Antioxidants (Basel, Switzerland) vol. 7,9 (2018). doi: https://doi.org/10.3390/antiox7090121
Alam S, Carter GS, Krager KJ, Li X, Lehmler HJ, Aykin-Burns N. PCB11 Metabolite, 3,3'-Dichlorobiphenyl-4-ol, Exposure Alters the Expression of Genes Governing Fatty Acid Metabolism in the Absence of Functional Sirtuin 3: Examining the Contribution of MnSOD. Antioxidants (Basel). 2018 Sep 15;7(9). doi: 10.3390/antiox7090121. PMID: 30223548; PMCID: PMC6162768.
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Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes.

Toxicology reports

Banerjee S, Melnyk SB, Krager KJ, Aykin-Burns N, McCullough SS, James LP, Hinson JA.
PMID: 28503408
Toxicol Rep. 2017;4:134-142. doi: 10.1016/j.toxrep.2017.02.005.

The hepatotoxicity of acetaminophen (APAP) occurs by initial metabolism to N-acetyl-p-benzoquinone imine which depletes GSH and forms APAP-protein adducts. Subsequently, the reactive nitrogen species peroxynitrite is formed from nitric oxide (NO) and superoxide leading to 3-nitrotyrosine in proteins. Toxicity...

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Banerjee S, Melnyk SB, Krager KJ, et al. Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes. Toxicol Rep. 2017;4:134-142doi: 10.1016/j.toxrep.2017.02.005.
Banerjee, S., Melnyk, S. B., Krager, K. J., Aykin-Burns, N., McCullough, S. S., James, L. P., & Hinson, J. A. (2017). Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes. Toxicology reports, 4134-142. https://doi.org/10.1016/j.toxrep.2017.02.005
Banerjee, Sudip, et al. "Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes." Toxicology reports vol. 4 (2017): 134-142. doi: https://doi.org/10.1016/j.toxrep.2017.02.005
Banerjee S, Melnyk SB, Krager KJ, Aykin-Burns N, McCullough SS, James LP, Hinson JA. Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes. Toxicol Rep. 2017;4:134-142. doi: 10.1016/j.toxrep.2017.02.005. PMID: 28503408; PMCID: PMC5426116.
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Tocotrienol-Rich Fraction from Rice Bran Demonstrates Potent Radiation Protection Activity.

Evidence-based complementary and alternative medicine : eCAM

Krager KJ, Pineda EN, Kharade SV, Kordsmeier M, Howard L, Breen PJ, Compadre CM, Hauer-Jensen M, Aykin-Burns N.
PMID: 26425129
Evid Based Complement Alternat Med. 2015;2015:148791. doi: 10.1155/2015/148791. Epub 2015 Aug 26.

The vitamin E analogs δ-tocotrienol (DT3) and γ-tocotrienol (GT3) have significant protective and mitigative capacity against the detrimental effects of ionizing radiation (IR). However, the expense of purification limits their potential use. This study examined the tocotrienol-rich fraction of...

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Krager KJ, Pineda EN, Kharade SV, et al. Tocotrienol-Rich Fraction from Rice Bran Demonstrates Potent Radiation Protection Activity. Evid Based Complement Alternat Med. 2015;2015:148791doi: 10.1155/2015/148791.
Krager, K. J., Pineda, E. N., Kharade, S. V., Kordsmeier, M., Howard, L., Breen, P. J., Compadre, C. M., Hauer-Jensen, M., & Aykin-Burns, N. (2015). Tocotrienol-Rich Fraction from Rice Bran Demonstrates Potent Radiation Protection Activity. Evidence-based complementary and alternative medicine : eCAM, 2015148791. https://doi.org/10.1155/2015/148791
Krager, Kimberly J, et al. "Tocotrienol-Rich Fraction from Rice Bran Demonstrates Potent Radiation Protection Activity." Evidence-based complementary and alternative medicine : eCAM vol. 2015 (2015): 148791. doi: https://doi.org/10.1155/2015/148791
Krager KJ, Pineda EN, Kharade SV, Kordsmeier M, Howard L, Breen PJ, Compadre CM, Hauer-Jensen M, Aykin-Burns N. Tocotrienol-Rich Fraction from Rice Bran Demonstrates Potent Radiation Protection Activity. Evid Based Complement Alternat Med. 2015;2015:148791. doi: 10.1155/2015/148791. Epub 2015 Aug 26. PMID: 26425129; PMCID: PMC4573888.
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An inhibitor of K+ channels modulates human endometrial tumor-initiating cells.

Cancer cell international

Schickling BM, Aykin-Burns N, Leslie KK, Spitz DR, Korovkina VP.
PMID: 21810252
Cancer Cell Int. 2011 Aug 02;11(1):25. doi: 10.1186/1475-2867-11-25.

BACKGROUND: Many potassium ion (K+) channels function as oncogenes to sustain growth of solid tumors, but their role in cancer progression is not well understood. Emerging evidence suggests that the early progenitor cancer cell subpopulation, termed tumor initiating cells...

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Schickling BM, Aykin-Burns N, Leslie KK, et al. An inhibitor of K+ channels modulates human endometrial tumor-initiating cells. Cancer Cell Int. 2011;11(1):25doi: 10.1186/1475-2867-11-25.
Schickling, B. M., Aykin-Burns, N., Leslie, K. K., Spitz, D. R., & Korovkina, V. P. (2011). An inhibitor of K+ channels modulates human endometrial tumor-initiating cells. Cancer cell international, 11(1), 25. https://doi.org/10.1186/1475-2867-11-25
Schickling, Brandon M, et al. "An inhibitor of K+ channels modulates human endometrial tumor-initiating cells." Cancer cell international vol. 11,1 (2011): 25. doi: https://doi.org/10.1186/1475-2867-11-25
Schickling BM, Aykin-Burns N, Leslie KK, Spitz DR, Korovkina VP. An inhibitor of K+ channels modulates human endometrial tumor-initiating cells. Cancer Cell Int. 2011 Aug 02;11(1):25. doi: 10.1186/1475-2867-11-25. PMID: 21810252; PMCID: PMC3175438.
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The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection.

bioRxiv : the preprint server for biology

McDonald JT, Enguita FJ, Taylor D, Griffin RJ, Priebe W, Emmett MR, Sajadi MM, Harris AD, Clement J, Dybas JM, Aykin-Burns N, Guarnieri JW, Singh LN, Grabham P, Baylin SB, Yousey A, Pearson AN, Corry PM, Saravia-Butler A, Aunins TR, Sharma S, Nagpal P, Meydan C, Foox J, Mozsary C, Cerqueira B, Zaksas V, Singh U, Wurtele ES, Costes SV, Davanzo GG, Galeano D, Paccanaro A, Meinig SL, Hagan RS, Bowman NM, Wolfgang MC, Altinok S, Sapoval N, Treangen TJ, Moraes-Vieira PM, Vanderburg C, Wallace DC, Schisler J, Mason CE, Chatterjee A, Meller R, Beheshti A.
PMID: 33948587
bioRxiv. 2021 Aug 18; doi: 10.1101/2021.04.23.441024.

MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene regulation that have a major impact on many diseases and provides an exciting avenue towards antiviral therapeutics. From patient transcriptomic data, we have discovered a circulating miRNA, miR-2392, that...

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McDonald JT, Enguita FJ, Taylor D, et al. The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection. bioRxiv. 2021;doi: 10.1101/2021.04.23.441024.
McDonald, J. T., Enguita, F. J., Taylor, D., Griffin, R. J., Priebe, W., Emmett, M. R., Sajadi, M. M., Harris, A. D., Clement, J., Dybas, J. M., Aykin-Burns, N., Guarnieri, J. W., Singh, L. N., Grabham, P., Baylin, S. B., Yousey, A., Pearson, A. N., Corry, P. M., Saravia-Butler, A., Aunins, T. R., Sharma, S., Nagpal, P., Meydan, C., Foox, J., Mozsary, C., Cerqueira, B., Zaksas, V., Singh, U., Wurtele, E. S., Costes, S. V., Davanzo, G. G., Galeano, D., Paccanaro, A., Meinig, S. L., Hagan, R. S., Bowman, N. M., Wolfgang, M. C., Altinok, S., Sapoval, N., Treangen, T. J., Moraes-Vieira, P. M., Vanderburg, C., Wallace, D. C., Schisler, J., Mason, C. E., Chatterjee, A., Meller, R., & Beheshti, A. (2021). The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection. bioRxiv : the preprint server for biology, . https://doi.org/10.1101/2021.04.23.441024
McDonald, J Tyson, et al. "The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection." bioRxiv : the preprint server for biology vol. (2021). doi: https://doi.org/10.1101/2021.04.23.441024
McDonald JT, Enguita FJ, Taylor D, Griffin RJ, Priebe W, Emmett MR, Sajadi MM, Harris AD, Clement J, Dybas JM, Aykin-Burns N, Guarnieri JW, Singh LN, Grabham P, Baylin SB, Yousey A, Pearson AN, Corry PM, Saravia-Butler A, Aunins TR, Sharma S, Nagpal P, Meydan C, Foox J, Mozsary C, Cerqueira B, Zaksas V, Singh U, Wurtele ES, Costes SV, Davanzo GG, Galeano D, Paccanaro A, Meinig SL, Hagan RS, Bowman NM, Wolfgang MC, Altinok S, Sapoval N, Treangen TJ, Moraes-Vieira PM, Vanderburg C, Wallace DC, Schisler J, Mason CE, Chatterjee A, Meller R, Beheshti A. The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection. bioRxiv. 2021 Aug 18; doi: 10.1101/2021.04.23.441024. PMID: 33948587; PMCID: PMC8095194.
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Modulation of Radiation Response by the Tetrahydrobiopterin Pathway.

Antioxidants (Basel, Switzerland)

Pathak R, Cheema AK, Boca SM, Krager KJ, Hauer-Jensen M, Aykin-Burns N.
PMID: 26785338
Antioxidants (Basel). 2015 Jan 22;4(1):68-81. doi: 10.3390/antiox4010068.

Ionizing radiation (IR) is an integral component of our lives due to highly prevalent sources such as medical, environmental, and/or accidental. Thus, understanding of the mechanisms by which radiation toxicity develops is crucial to address acute and chronic health...

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Pathak R, Cheema AK, Boca SM, et al. Modulation of Radiation Response by the Tetrahydrobiopterin Pathway. Antioxidants (Basel). 2015;4(1):68-81doi: 10.3390/antiox4010068.
Pathak, R., Cheema, A. K., Boca, S. M., Krager, K. J., Hauer-Jensen, M., & Aykin-Burns, N. (2015). Modulation of Radiation Response by the Tetrahydrobiopterin Pathway. Antioxidants (Basel, Switzerland), 4(1), 68-81. https://doi.org/10.3390/antiox4010068
Pathak, Rupak, et al. "Modulation of Radiation Response by the Tetrahydrobiopterin Pathway." Antioxidants (Basel, Switzerland) vol. 4,1 (2015): 68-81. doi: https://doi.org/10.3390/antiox4010068
Pathak R, Cheema AK, Boca SM, Krager KJ, Hauer-Jensen M, Aykin-Burns N. Modulation of Radiation Response by the Tetrahydrobiopterin Pathway. Antioxidants (Basel). 2015 Jan 22;4(1):68-81. doi: 10.3390/antiox4010068. PMID: 26785338; PMCID: PMC4665563.
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The Role of Sirtuin 3 in Radiation-Induced Long-Term Persistent Liver Injury.

Antioxidants (Basel, Switzerland)

LoBianco FV, Krager KJ, Carter GS, Alam S, Yuan Y, Lavoie EG, Dranoff JA, Aykin-Burns N.
PMID: 32403251
Antioxidants (Basel). 2020 May 11;9(5). doi: 10.3390/antiox9050409.

In patients with abdominal region cancers, ionizing radiation (IR)-induced long-term liver injury is a major limiting factor in the use of radiotherapy. Previously, the major mitochondrial deacetylase, sirtuin 3 (SIRT3), has been implicated to play an important role in...

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LoBianco FV, Krager KJ, Carter GS, et al. The Role of Sirtuin 3 in Radiation-Induced Long-Term Persistent Liver Injury. Antioxidants (Basel). 2020;9(5)doi: 10.3390/antiox9050409.
LoBianco, F. V., Krager, K. J., Carter, G. S., Alam, S., Yuan, Y., Lavoie, E. G., Dranoff, J. A., & Aykin-Burns, N. (2020). The Role of Sirtuin 3 in Radiation-Induced Long-Term Persistent Liver Injury. Antioxidants (Basel, Switzerland), 9(5), . https://doi.org/10.3390/antiox9050409
LoBianco, Francesca V, et al. "The Role of Sirtuin 3 in Radiation-Induced Long-Term Persistent Liver Injury." Antioxidants (Basel, Switzerland) vol. 9,5 (2020). doi: https://doi.org/10.3390/antiox9050409
LoBianco FV, Krager KJ, Carter GS, Alam S, Yuan Y, Lavoie EG, Dranoff JA, Aykin-Burns N. The Role of Sirtuin 3 in Radiation-Induced Long-Term Persistent Liver Injury. Antioxidants (Basel). 2020 May 11;9(5). doi: 10.3390/antiox9050409. PMID: 32403251; PMCID: PMC7278565.
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The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection.

bioRxiv : the preprint server for biology

McDonald JT, Enguita FJ, Taylor D, Griffin RJ, Priebe W, Emmett MR, McGrath M, Sajadi MM, Harris AD, Clement J, Dybas JM, Aykin-Burns N, Guarnieri JW, Singh LN, Grabham P, Baylin SB, Yousey A, Pearson AN, Corry PM, Saravia-Butler A, Aunins TR, Nagpal P, Meydan C, Foox J, Mozsary C, Cerqueira B, Zaksas V, Singh U, Wurtele ES, Costes SV, Galeano D, Paccanaro A, Meinig SL, Hagan RS, Bowman NM, Wolfgang MC, Altinok S, Sapoval N, Treangen TJ, Frieman M, Vanderburg C, Wallace DC, Schisler J, Mason CE, Chatterjee A, Meller R, Beheshti A.
PMID: 33948587
bioRxiv. 2021 Apr 27; doi: 10.1101/2021.04.23.441024.

MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene regulation that have a major impact on many diseases and provides an exciting avenue towards antiviral therapeutics. From patient transcriptomic data, we have discovered a circulating miRNA, miR-2392, that...

Cite
McDonald JT, Enguita FJ, Taylor D, et al. The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection. bioRxiv. 2021;doi: 10.1101/2021.04.23.441024.
McDonald, J. T., Enguita, F. J., Taylor, D., Griffin, R. J., Priebe, W., Emmett, M. R., McGrath, M., Sajadi, M. M., Harris, A. D., Clement, J., Dybas, J. M., Aykin-Burns, N., Guarnieri, J. W., Singh, L. N., Grabham, P., Baylin, S. B., Yousey, A., Pearson, A. N., Corry, P. M., Saravia-Butler, A., Aunins, T. R., Nagpal, P., Meydan, C., Foox, J., Mozsary, C., Cerqueira, B., Zaksas, V., Singh, U., Wurtele, E. S., Costes, S. V., Galeano, D., Paccanaro, A., Meinig, S. L., Hagan, R. S., Bowman, N. M., Wolfgang, M. C., Altinok, S., Sapoval, N., Treangen, T. J., Frieman, M., Vanderburg, C., Wallace, D. C., Schisler, J., Mason, C. E., Chatterjee, A., Meller, R., & Beheshti, A. (2021). The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection. bioRxiv : the preprint server for biology, . https://doi.org/10.1101/2021.04.23.441024
McDonald, J Tyson, et al. "The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection." bioRxiv : the preprint server for biology vol. (2021). doi: https://doi.org/10.1101/2021.04.23.441024
McDonald JT, Enguita FJ, Taylor D, Griffin RJ, Priebe W, Emmett MR, McGrath M, Sajadi MM, Harris AD, Clement J, Dybas JM, Aykin-Burns N, Guarnieri JW, Singh LN, Grabham P, Baylin SB, Yousey A, Pearson AN, Corry PM, Saravia-Butler A, Aunins TR, Nagpal P, Meydan C, Foox J, Mozsary C, Cerqueira B, Zaksas V, Singh U, Wurtele ES, Costes SV, Galeano D, Paccanaro A, Meinig SL, Hagan RS, Bowman NM, Wolfgang MC, Altinok S, Sapoval N, Treangen TJ, Frieman M, Vanderburg C, Wallace DC, Schisler J, Mason CE, Chatterjee A, Meller R, Beheshti A. The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection. bioRxiv. 2021 Apr 27; doi: 10.1101/2021.04.23.441024. PMID: 33948587; PMCID: PMC8095194.
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