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Showing 1 to 12 of 55 entries
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Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins.

Frontiers in aging neuroscience

Starnawska A, Tan Q, McGue M, Mors O, Børglum AD, Christensen K, Nyegaard M, Christiansen L.
PMID: 29311901
Front Aging Neurosci. 2017 Dec 12;9:413. doi: 10.3389/fnagi.2017.00413. eCollection 2017.

As the world's population ages, the age-related cognitive decline presents a great challenge to world's healthcare systems. One of the molecular mechanisms implicated in cognitive ageing is DNA methylation, an epigenetic modification known to be a key player in...

An Obturator Nerve Block does not Alleviate Postoperative Pain after Total Hip Arthroplasty: a Randomized Clinical Trial.

Regional anesthesia and pain medicine

Nielsen ND, Runge C, Clemmesen L, Børglum J, Mikkelsen LR, Larsen JR, Nielsen TD, Søballe K, Bendtsen TF.
PMID: 30679337
Reg Anesth Pain Med. 2019 Jan 23; doi: 10.1136/rapm-2018-100104. Epub 2019 Jan 23.

BACKGROUND AND OBJECTIVES: A substantial group of patients suffer from moderate to severe pain following elective total hip arthroplasty (THA). Due to the complex innervation of the hip, peripheral nerve block techniques can be challenging and are not widely...

Comparing Copy Number Variations in a Danish Case Cohort of Individuals With Psychiatric Disorders.

JAMA psychiatry

Calle Sánchez X, Helenius D, Bybjerg-Grauholm J, Pedersen C, Hougaard DM, Børglum AD, Nordentoft M, Mors O, Mortensen PB, Geschwind DH, Montalbano S, Raznahan A, Thompson WK, Ingason A, Werge T.
PMID: 34817560
JAMA Psychiatry. 2022 Jan 01;79(1):59-69. doi: 10.1001/jamapsychiatry.2021.3392.

IMPORTANCE: Although the association between several recurrent genomic copy number variants (CNVs) and mental disorders has been studied for more than a decade, unbiased, population-based estimates of the prevalence, disease risks and trajectories, fertility, and mortality to contrast chromosomal...

Reply to: Cervical plexus and greater occipital nerve blocks: controversies and technique update.

Regional anesthesia and pain medicine

Greher M, Moriggl B, Børglum J.
PMID: 31213491
Reg Anesth Pain Med. 2019 Jun 18; doi: 10.1136/rapm-2019-100736. Epub 2019 Jun 18.

No abstract available.

Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors.

Nature communications

Krebs MD, Themudo GE, Benros ME, Mors O, Børglum AD, Hougaard D, Mortensen PB, Nordentoft M, Gandal MJ, Fan CC, Geschwind DH, Schork AJ, Werge T, Thompson WK.
PMID: 34785645
Nat Commun. 2021 Nov 16;12(1):6617. doi: 10.1038/s41467-021-26903-7.

Schizophrenia is a heterogeneous disorder, exhibiting variability in presentation and outcomes that complicate treatment and recovery. To explore this heterogeneity, we leverage the comprehensive Danish health registries to conduct a prospective, longitudinal study from birth of 5432 individuals who...

Correction: Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorder.

European journal of human genetics : EJHG

Nudel R, Benros ME, Krebs MD, Allesøe RL, Lemvigh CK, Bybjerg-Grauholm J, Børglum AD, Daly MJ, Nordentoft M, Mors O, Hougaard DM, Mortensen PB, Buil A, Werge T, Rasmussen S, Thompson WK.
PMID: 33293699
Eur J Hum Genet. 2021 Aug;29(8):1316. doi: 10.1038/s41431-020-00772-y.

No abstract available.

Gestational age-dependent development of the neonatal metabolome.

Pediatric research

Ernst M, Rogers S, Lausten-Thomsen U, Björkbom A, Laursen SS, Courraud J, Børglum A, Nordentoft M, Werge T, Mortensen PB, Hougaard DM, Cohen AS.
PMID: 32942288
Pediatr Res. 2021 May;89(6):1396-1404. doi: 10.1038/s41390-020-01149-z. Epub 2020 Sep 17.

BACKGROUND: Prematurity is a severe pathophysiological condition, however, little is known about the gestational age-dependent development of the neonatal metabolome.METHODS: Using an untargeted liquid chromatography-tandem mass spectrometry metabolomics protocol, we measured over 9000 metabolites in 298 neonatal residual heel...

Images of the thoracic paravertebral space: a demanding dance with the devil in the details.

Regional anesthesia and pain medicine

Nielsen MV, Tanggaard K, Hansen CK, Børglum J, Moriggl B.
PMID: 34759040
Reg Anesth Pain Med. 2021 Nov 10; doi: 10.1136/rapm-2021-103156. Epub 2021 Nov 10.

No abstract available.

Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder.

Nature communications

Demontis D, Walters RK, Rajagopal VM, Waldman ID, Grove J, Als TD, Dalsgaard S, Ribasés M, Bybjerg-Grauholm J, Bækvad-Hansen M, Werge T, Nordentoft M, Mors O, Mortensen PB, Cormand B, Hougaard DM, Neale BM, Franke B, Faraone SV, Børglum AD.
PMID: 33589642
Nat Commun. 2021 Feb 15;12(1):1166. doi: 10.1038/s41467-021-21566-w.

No abstract available.

Comparing Copy Number Variations in a Danish Case Cohort of Individuals With Psychiatric Disorders.

JAMA psychiatry

Calle Sánchez X, Helenius D, Bybjerg-Grauholm J, Pedersen C, Hougaard DM, Børglum AD, Nordentoft M, Mors O, Mortensen PB, Geschwind DH, Montalbano S, Raznahan A, Thompson WK, Ingason A, Werge T.
PMID: 34817560
JAMA Psychiatry. 2022 Jan 01;79(1):59-69. doi: 10.1001/jamapsychiatry.2021.3392.

IMPORTANCE: Although the association between several recurrent genomic copy number variants (CNVs) and mental disorders has been studied for more than a decade, unbiased, population-based estimates of the prevalence, disease risks and trajectories, fertility, and mortality to contrast chromosomal...

Early-Life Injuries and the Development of Attention-Deficit/Hyperactivity Disorder.

The Journal of clinical psychiatry

Wimberley T, Brikell I, Pedersen EM, Agerbo E, Vilhjálmsson BJ, Albiñana C, Privé F, Thapar A, Langley K, Riglin L, Simonsen M, Nielsen HS, Børglum AD, Nordentoft M, Mortensen PB, Dalsgaard S.
PMID: 34985833
J Clin Psychiatry. 2022 Jan 04;83(1). doi: 10.4088/JCP.21m14033.

No abstract available.

Ultrasound-guided multiple-injection costotransverse block for mastectomy and primary reconstructive surgery. A study protocol.

Acta anaesthesiologica Scandinavica

Holm UHU, Andersen CHS, Hansen CK, Tanggaard K, Børglum J, Nielsen MV.
PMID: 34907523
Acta Anaesthesiol Scand. 2021 Dec 14; doi: 10.1111/aas.14018. Epub 2021 Dec 14.

BACKGROUND: Post-operative pain amelioration following breast cancer surgery is inconsistent. The novel multiple-injection costotransverse block (MICB) mimics the thoracic paravertebral block by possible anaesthetising the ventral rami of the thoracic spinal nerves and the sympathetic trunk. Proof of concept...

Showing 1 to 12 of 55 entries