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Showing 1 to 12 of 45 entries
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Global Initiative for Asthma (GINA) Strategy 2021 - Executive summary and rationale for key changes.

The European respiratory journal

Reddel HK, Bacharier LB, Bateman ED, Brightling CE, Brusselle GG, Buhl R, Cruz AA, Duijts L, Drazen JM, FitzGerald JM, Fleming LJ, Inoue H, Ko FW, Krishnan JA, Levy ML, Lin J, Mortimer K, Pitrez PM, Sheikh A, Yorgancioglu AA, Boulet LP.
PMID: 34667060
Eur Respir J. 2021 Oct 19; doi: 10.1183/13993003.02730-2021. Epub 2021 Oct 19.

The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually updated evidence-based strategy for asthma management and prevention, which can be adapted for local circumstances (e.g., medication availability). This article summarizes key recommendations from GINA 2021,...

Violence-related distress and lung function in two longitudinal studies of youth.

The European respiratory journal

Gaietto K, Han YY, Forno E, Bacharier LB, Phipatanakul W, Guilbert TW, Cabana MD, Ross K, Blatter J, Acosta-Pérez E, Miller GE, de la Hoz RE, Rosser FJ, Durrani S, Canino G, Wisniewski SR, Celedón JC.
PMID: 34588198
Eur Respir J. 2021 Sep 29; doi: 10.1183/13993003.02329-2021. Epub 2021 Sep 29.

Increasing violence-related distress over time was associated with worse lung function and worse asthma-related quality of life in youth with asthma despite treatment with low-dose inhaled corticosteroids.Exposure to violence has been associated with lower lung function in cross-sectional studies....

A distributed geospatial approach to describe community characteristics for multisite studies.

Journal of clinical and translational science

Ryan PH, Brokamp C, Blossom J, Lothrop N, Miller RL, Beamer PI, Visness CM, Zanobetti A, Andrews H, Bacharier LB, Hartert T, Johnson CC, Ownby D, Lemanske RF, Gibson H, Requia W, Coull B, Zoratti EM, Wright AL, Martinez FD, Seroogy CM, Gern JE, Gold DR.
PMID: 34007469
J Clin Transl Sci. 2021 Feb 05;5(1):e86. doi: 10.1017/cts.2021.7.

Understanding place-based contributors to health requires geographically and culturally diverse study populations, but sharing location data is a significant challenge to multisite studies. Here, we describe a standardized and reproducible method to perform geospatial analyses for multisite studies. Using...

Global Initiative for Asthma (GINA) Strategy 2021 - Executive summary and rationale for key changes.

Respirology (Carlton, Vic.)

Reddel HK, Bacharier LB, Bateman ED, Brightling CE, Brusselle GG, Buhl R, Cruz AA, Duijts L, Drazen JM, FitzGerald JM, Fleming LJ, Inoue H, Ko FW, Krishnan JA, Levy ML, Lin J, Mortimer K, Pitrez PM, Sheikh A, Yorgancioglu AA, Boulet LP.
PMID: 34668278
Respirology. 2021 Oct 19; doi: 10.1111/resp.14174. Epub 2021 Oct 19.

The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually updated evidence-based strategy for asthma management and prevention, which can be adapted for local circumstances (e.g., medication availability). This article summarizes key recommendations from GINA 2021,...

Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children.

The Journal of allergy and clinical immunology

Altman MC, Flynn K, Rosasco MG, Dapas M, Kattan M, Lovinsky-Desir S, O'Connor GT, Gill MA, Gruchalla RS, Liu AH, Pongracic JA, Khurana Hershey GK, Zoratti EM, Teach SJ, Rastrogi D, Wood RA, Bacharier LB, LeBeau P, Gergen PJ, Togias A, Busse WW, Presnell S, Gern JE, Ober C, Jackson DJ.
PMID: 34019912
J Allergy Clin Immunol. 2021 Dec;148(6):1505-1514. doi: 10.1016/j.jaci.2021.04.035. Epub 2021 May 18.

BACKGROUND: Mucus plugging can worsen asthma control, lead to reduced lung function and fatal exacerbations. MUC5AC is the secretory mucin implicated in mucus plugging, and MUC5AC gene expression has been associated with development of airway obstruction and asthma exacerbations...

Long-Term Respiratory Consequences of Early-Life Respiratory Viral Infections: A Pragmatic Approach to Fundamental Questions.

The journal of allergy and clinical immunology. In practice

Achten NB, van Rossum AMC, Bacharier LB, Fitzpatrick AM, Hartert TV.
PMID: 34942383
J Allergy Clin Immunol Pract. 2021 Dec 20; doi: 10.1016/j.jaip.2021.12.005. Epub 2021 Dec 20.

Early-life viral infection can have profound effects on the developing lung and immune systems, both important in asthma development. For decades, research has aimed to establish whether there is a causal link between these viral infections as an exposure...

Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma.

The Lancet. Child & adolescent health

Ortega VE, Daya M, Szefler SJ, Bleecker ER, Chinchilli VM, Phipatanakul W, Mauger D, Martinez FD, Herrera-Luis E, Pino-Yanes M, Hawkins GA, Ampleford EJ, Kunselman SJ, Cox C, Bacharier LB, Cabana MD, Cardet JC, Castro M, Denlinger LC, Eng C, Fitzpatrick AM, Holguin F, Hu D, Jackson DJ, Jarjour N, Kraft M, Krishnan JA, Lazarus SC, Lemanske RF, Lima JJ, Lugogo N, Mak A, Moore WC, Naureckas ET, Peters SP, Pongracic JA, Sajuthi SP, Seibold MA, Smith LJ, Solway J, Sorkness CA, Wenzel S, White SR, Burchard EG, Barnes K, Meyers DA, Israel E, Wechsler ME.
PMID: 34762840
Lancet Child Adolesc Health. 2021 Dec;5(12):862-872. doi: 10.1016/S2352-4642(21)00268-6. Epub 2021 Nov 09.

BACKGROUND: Pharmacogenetic studies in asthma cohorts, primarily made up of White people of European descent, have identified loci associated with response to inhaled beta agonists and corticosteroids (ICSs). Differences exist in how individuals from different ancestral backgrounds respond to...

The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions.

The Journal of allergy and clinical immunology

Georas SN, Wright RJ, Ivanova A, Israel E, LaVange LM, Akuthota P, Carr TF, Denlinger LC, Fajt ML, Kumar R, O'Neal WK, Phipatanakul W, Szefler SJ, Aronica MA, Bacharier LB, Burbank AJ, Castro M, Crotty Alexander L, Bamdad J, Cardet JC, Comhair SAA, Covar RA, DiMango EA, Erwin K, Erzurum SC, Fahy JV, Gaffin JM, Gaston B, Gerald LB, Hoffman EA, Holguin F, Jackson DJ, James J, Jarjour NN, Kenyon NJ, Khatri S, Kirwan JP, Kraft M, Krishnan JA, Liu AH, Liu MC, Marquis MA, Martinez F, Mey J, Moore WC, Moy JN, Ortega VE, Peden DB, Pennington E, Peters MC, Ross K, Sanchez M, Smith LJ, Sorkness RL, Wechsler ME, Wenzel SE, White SR, Zein J, Zeki AA, Noel P.
PMID: 34848210
J Allergy Clin Immunol. 2021 Nov 29; doi: 10.1016/j.jaci.2021.10.035. Epub 2021 Nov 29.

Asthma is a heterogeneous disease, with multiple underlying inflammatory pathways and structural airway abnormalities that impact disease persistence and severity. Recent progress has been made in developing targeted asthma therapeutics, especially for subjects with eosinophilic asthma. However, there is...

Global Initiative for Asthma (GINA) Strategy 2021 - Executive summary and rationale for key changes.

The journal of allergy and clinical immunology. In practice

Reddel HK, Bacharier LB, Bateman ED, Brightling CE, Brusselle GG, Buhl R, Cruz AA, Duijts L, Drazen JM, FitzGerald JM, Fleming LJ, Inoue H, Ko FW, Krishnan JA, Levy ML, Lin J, Mortimer K, Pitrez PM, Sheikh A, Yorgancioglu AA, Boulet LP.
PMID: 34718211
J Allergy Clin Immunol Pract. 2021 Oct 27; doi: 10.1016/j.jaip.2021.10.001. Epub 2021 Oct 27.

The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually updated evidence-based strategy for asthma management and prevention, which can be adapted for local circumstances (e.g., medication availability). This article summarizes key recommendations from GINA 2021,...

Prospective Observational Study of Clinical Outcomes After Intravenous Magnesium for Moderate and Severe Acute Asthma Exacerbations in Children.

The journal of allergy and clinical immunology. In practice

Arnold DH, Gong W, Antoon JW, Bacharier LB, Stewart TG, Johnson DP, Akers WS, Hartert TV.
PMID: 34915226
J Allergy Clin Immunol Pract. 2021 Dec 13; doi: 10.1016/j.jaip.2021.11.028. Epub 2021 Dec 13.

BACKGROUND: There is limited knowledge regarding whether intravenous magnesium (IV-Mg) improves outcomes in children with acute asthma exacerbations.OBJECTIVE: To examine whether IV-Mg improves outcomes in children with moderate and severe exacerbations.METHODS: We performed a secondary analysis using data from...

17q12-q21 variants interact with early-life exposures to modify asthma risk in Black children.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Gereige JD, Morin A, Calatroni A, Visness CM, Wood RA, Kattan M, Bacharier LB, Becker P, Altman MC, Gern JE, Ober C, O'Connor GT.
PMID: 34862819
Clin Exp Allergy. 2021 Dec 04; doi: 10.1111/cea.14074. Epub 2021 Dec 04.

Genetic factors and early-life exposures

17q12-q21 variants interact with early-life exposures to modify asthma risk in Black children.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Gereige JD, Morin A, Calatroni A, Visness CM, Wood RA, Kattan M, Bacharier LB, Becker P, Altman MC, Gern JE, Ober C, O'Connor GT.
PMID: 34862819
Clin Exp Allergy. 2021 Dec 04; doi: 10.1111/cea.14074. Epub 2021 Dec 04.

No abstract available.

Showing 1 to 12 of 45 entries