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Showing 1 to 12 of 199 entries
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The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2,7-Diazaspiro[3.5]nonane) and Spirocyclic Piperidine-Pyrrolidine (2,8-Diazaspiro[4.5]decane) Ring Systems.

The Journal of organic chemistry

Smith AC, Cabral S, Kung DW, Rose CR, Southers JA, García-Irizarry CN, Damon DB, Bagley SW, Griffith DA.
PMID: 27056793
J Org Chem. 2016 May 06;81(9):3509-19. doi: 10.1021/acs.joc.5b02890. Epub 2016 Apr 25.

The synthesis of a series of pharmaceutically important N-protected methyl-substituted spirocyclic piperidine-azetidine (2,7-diazaspiro[3.5]nonane) and spirocyclic piperidine-pyrrolidine (2,8-diazaspiro[4.5]decane) ring systems was developed. These motifs contain two differentiated sites (protected secondary amines) to allow for further functionalization via reductive amination, amidation,...

Giant, completely calcified lumbar juxtafacet cyst: report of an unusual case.

Global spine journal

Huang KT, Owens TR, Wang TS, Moreno JR, Bagley JH, Bagley CA.
PMID: 25083359
Global Spine J. 2014 Aug;4(3):175-8. doi: 10.1055/s-0033-1363591. Epub 2013 Dec 19.

Study Design Case report. Objective To report the case of one patient who developed a giant, completely calcified, juxtafacet cyst. Methods A 57-year-old woman presented with a 2-year history of progressively worsening lower back pain, left leg pain, weakness,...

Temporal soliton switching in a rectangular nonlinear directional coupler.

Applied optics

Sala AL, Bagley BG, Deck RT.
PMID: 18324008
Appl Opt. 1999 Aug 20;38(24):5133-43. doi: 10.1364/ao.38.005133.

We address the theory of temporal soliton switching in a planar geometry directional coupler constructed from silica and doped silica glass and operating at the central wavelength of 1.55 microm, significant for erbium-doped amplification. We formulate the field in...

Derivation of dimensional and material requirements for propagation and processing of temporal optical solitons in planar geometry channel waveguides.

Applied optics

Sala AL, Mirkov MG, Bagley BG, Deck RT.
PMID: 18264311
Appl Opt. 1997 Oct 20;36(30):7846-52. doi: 10.1364/ao.36.007846.

We investigate the dispersion of the group velocity of light in slab and rectangular waveguides and obtain analytic expressions for the first derivative of the propagation vector with respect to the angular frequency and numerical values for the second...

Evaluation of chronic pain-related information available to consumers on the Internet.

Pain medicine (Malden, Mass.)

Bailey SJ, LaChapelle DL, LeFort SM, Gordon A, Hadjistavropoulos T.
PMID: 23565667
Pain Med. 2013 Jun;14(6):855-64. doi: 10.1111/pme.12087. Epub 2013 Apr 08.

OBJECTIVE: Recent surveys suggest more than one third of patients utilize the Internet to seek information about chronic pain (CP) and that 60% of patients feel more confident in the information provided online than provided by their physician. Unfortunately,...

Immediate Postoperative Pain Scores Predict Neck Pain Profile up to 1 Year Following Anterior Cervical Discectomy and Fusion.

Global spine journal

Adogwa O, Elsamadicy AA, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO.
PMID: 29796370
Global Spine J. 2018 May;8(3):231-236. doi: 10.1177/2192568217706700. Epub 2017 May 31.

STUDY DESIGN: Retrospective cohort review.OBJECTIVE: To assess whether immediate postoperative neck pain scores accurately predict 12-month visual analog scale-neck pain (VAS-NP) outcomes following Anterior Cervical Discectomy and Fusion surgery (ACDF).METHODS: This was a retrospective study of 82 patients undergoing...

Exploring emergency nurse practitioners' perceptions of their role.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)

Bagley S.
PMID: 29465212
Nurs Stand. 2018 Feb 21;32(26):41-50. doi: 10.7748/ns.2018.e10776.

Since the 1980s, the emergency nurse practitioner (ENP) role has evolved as increasing socioeconomic pressures and changing government policy have led to new working practices in emergency departments. Similarly, a lack of consensus regarding educational support for ENPs and...

Informed baseline subtraction of proteomic mass spectrometry data aided by a novel sliding window algorithm.

Proteome science

Stanford TE, Bagley CJ, Solomon PJ.
PMID: 27980460
Proteome Sci. 2016 Dec 07;14:19. doi: 10.1186/s12953-016-0107-8. eCollection 2016.

BACKGROUND: Proteomic matrix-assisted laser desorption/ionisation (MALDI) linear time-of-flight (TOF) mass spectrometry (MS) may be used to produce protein profiles from biological samples with the aim of discovering biomarkers for disease. However, the raw protein profiles suffer from several sources...

Assessing the effectiveness of routine use of post-operative in-patient physical therapy services.

Journal of spine surgery (Hong Kong)

Adogwa O, Elsamadicy AA, Fialkoff J, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Karikari IO, Bagley CA.
PMID: 28744494
J Spine Surg. 2017 Jun;3(2):149-154. doi: 10.21037/jss.2017.04.03.

BACKGROUND: The association between functional decline occurring with prolonged bed rest after surgery is well-known. Immediate in-patient post-operative ambulation with the physical therapy (PT) service has been reported to improve pain and disability, while decreasing the incidence of perioperative...

Central sensitization of the spino-parabrachial-amygdala pathway that outlasts a brief nociceptive stimulus.

The Journal of physiology

Kissiwaa SA, Bagley EE.
PMID: 30004124
J Physiol. 2018 Jul 13; doi: 10.1113/JP273976. Epub 2018 Jul 13.

KEY POINTS: Chronic pain is disabling because sufferers form negative associations between pain and activities, such as work, leading to the sufferer limiting these activities. Pain information arriving in the amygdala is responsible for forming these associations and contributes...

Rhode Island Domestic Violence Shelter Policies, Practices, and Experiences Pertaining to Survivors With Opioid Use Disorder: Results of a Qualitative Study.

Substance abuse : research and treatment

Rothman EF, Stone R, Bagley SM.
PMID: 30505145
Subst Abuse. 2018 Nov 27;12:1178221818812895. doi: 10.1177/1178221818812895. eCollection 2018.

The purpose of this study was to fill a gap in the existing research by exploring policies and practices of domestic violence shelters in one US state pertaining to clients with opioid use disorders (OUDs), as well as documenting...

Clinical construct validity.

Journal of advanced nursing

Nagley SJ, Byers PH.
PMID: 3693718
J Adv Nurs. 1987 Sep;12(5):617-9. doi: 10.1111/j.1365-2648.1987.tb03053.x.

When concepts and the 'paper and pencil' tests used to measure these concepts are developed in fields other than nursing and subsequently are used for nursing purposes, the perspective mismatch heralds a validity issue. This paper presents a case...

Showing 1 to 12 of 199 entries