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Showing 1 to 7 of 7 entries
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Intravenous immune globulin suppresses angiogenesis in mice and humans.

Signal transduction and targeted therapy

Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J.
PMID: 26925256
Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.2. Epub 2016 Jan 28.

Human intravenous immune globulin (IVIg), a purified IgG fraction composed of ~ 60% IgG1 and obtained from the pooled plasma of thousands of donors, is clinically used for a wide range of diseases. The biological actions of IVIg are...

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Yasuma R, Cicatiello V, Mizutani T, et al. Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal Transduct Target Ther. 2016;1doi: 10.1038/sigtrans.2015.2.
Yasuma, R., Cicatiello, V., Mizutani, T., Tudisco, L., Kim, Y., Tarallo, V., Bogdanovich, S., Hirano, Y., Kerur, N., Li, S., Yasuma, T., Fowler, B. J., Wright, C. B., Apicella, I., Greco, A., Brunetti, A., Ambati, B. K., Helmers, S. B., Lundberg, I. E., Viklicky, O., Leusen, J. H., Verbeek, J. S., Gelfand, B. D., Bastos-Carvalho, A., De Falco, S., & Ambati, J. (2016). Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal transduction and targeted therapy, 1. https://doi.org/10.1038/sigtrans.2015.2
Yasuma, Reo, et al. "Intravenous immune globulin suppresses angiogenesis in mice and humans." Signal transduction and targeted therapy vol. 1 (2016). doi: https://doi.org/10.1038/sigtrans.2015.2
Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J. Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.2. Epub 2016 Jan 28. PMID: 26925256; PMCID: PMC4768485.
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Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Figueiredo J, Ferreira RM, Xu H, Gonçalves M, Barros-Carvalho A, Cravo J, Maia AF, Carneiro P, Figueiredo C, Smith ML, Stamenović D, Morais-de-Sá E, Seruca R.
PMID: 34486077
Gastric Cancer. 2021 Sep 05; doi: 10.1007/s10120-021-01239-9. Epub 2021 Sep 05.

BACKGROUND: Tumour progression relies on the ability of cancer cells to penetrate and invade neighbouring tissues. E-cadherin loss is associated with increased cell invasion in gastric carcinoma, and germline mutations of the E-cadherin gene are causative of hereditary diffuse...

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Figueiredo J, Ferreira RM, Xu H, et al. Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells. Gastric Cancer. 2021;doi: 10.1007/s10120-021-01239-9.
Figueiredo, J., Ferreira, R. M., Xu, H., Gonçalves, M., Barros-Carvalho, A., Cravo, J., Maia, A. F., Carneiro, P., Figueiredo, C., Smith, M. L., Stamenović, D., Morais-de-Sá, E., & Seruca, R. (2021). Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, . https://doi.org/10.1007/s10120-021-01239-9
Figueiredo, Joana, et al. "Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells." Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association vol. (2021). doi: https://doi.org/10.1007/s10120-021-01239-9
Figueiredo J, Ferreira RM, Xu H, Gonçalves M, Barros-Carvalho A, Cravo J, Maia AF, Carneiro P, Figueiredo C, Smith ML, Stamenović D, Morais-de-Sá E, Seruca R. Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells. Gastric Cancer. 2021 Sep 05; doi: 10.1007/s10120-021-01239-9. Epub 2021 Sep 05. PMID: 34486077.
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Cell-Based Therapies for Heart Failure.

Frontiers in pharmacology

Campos de Carvalho AC, Kasai-Brunswick TH, Bastos Carvalho A.
PMID: 33912054
Front Pharmacol. 2021 Apr 12;12:641116. doi: 10.3389/fphar.2021.641116. eCollection 2021.

Heart failure has reached epidemic proportions with the advances in cardiovascular therapies for ischemic heart diseases and the progressive aging of the world population. Efficient pharmacological therapies are available for treating heart failure, but unfortunately, even with optimized therapy,...

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Campos de Carvalho AC, Kasai-Brunswick TH, Bastos Carvalho A. Cell-Based Therapies for Heart Failure. Front Pharmacol. 2021;12:641116doi: 10.3389/fphar.2021.641116.
Campos de Carvalho, A. C., Kasai-Brunswick, T. H., & Bastos Carvalho, A. (2021). Cell-Based Therapies for Heart Failure. Frontiers in pharmacology, 12641116. https://doi.org/10.3389/fphar.2021.641116
Campos de Carvalho, Antonio Carlos, et al. "Cell-Based Therapies for Heart Failure." Frontiers in pharmacology vol. 12 (2021): 641116. doi: https://doi.org/10.3389/fphar.2021.641116
Campos de Carvalho AC, Kasai-Brunswick TH, Bastos Carvalho A. Cell-Based Therapies for Heart Failure. Front Pharmacol. 2021 Apr 12;12:641116. doi: 10.3389/fphar.2021.641116. eCollection 2021. PMID: 33912054; PMCID: PMC8072383.
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Leukocoria in a child with sturge-weber syndrome.

The neuroradiology journal

Geraldo AF, Bastos-Carvalho A, Neto LL, Sousa RF, Sequeira PT, Campos J.
PMID: 24028881
Neuroradiol J. 2012 Mar;25(1):85-8. doi: 10.1177/197140091202500112. Epub 2012 Mar 01.

A five-year-old girl with Sturge-Weber syndrome (SWS) presented with unilateral leukocoria. Imaging excluded retinoblastoma and revealed a choroidal hemangioma, a non-traumatic vitreous hemorrhage and a cataract. To the best of our knowledge, this is the first case report in...

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Geraldo AF, Bastos-Carvalho A, Neto LL, et al. Leukocoria in a child with sturge-weber syndrome. Neuroradiol J. 2012;25(1):85-8doi: 10.1177/197140091202500112.
Geraldo, A. F., Bastos-Carvalho, A., Neto, L. L., Sousa, R. F., Sequeira, P. T., & Campos, J. (2012). Leukocoria in a child with sturge-weber syndrome. The neuroradiology journal, 25(1), 85-8. https://doi.org/10.1177/197140091202500112
Geraldo, A F, et al. "Leukocoria in a child with sturge-weber syndrome." The neuroradiology journal vol. 25,1 (2012): 85-8. doi: https://doi.org/10.1177/197140091202500112
Geraldo AF, Bastos-Carvalho A, Neto LL, Sousa RF, Sequeira PT, Campos J. Leukocoria in a child with sturge-weber syndrome. Neuroradiol J. 2012 Mar;25(1):85-8. doi: 10.1177/197140091202500112. Epub 2012 Mar 01. PMID: 24028881.
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Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Figueiredo J, Ferreira RM, Xu H, Gonçalves M, Barros-Carvalho A, Cravo J, Maia AF, Carneiro P, Figueiredo C, Smith ML, Stamenović D, Morais-de-Sá E, Seruca R.
PMID: 34486077
Gastric Cancer. 2022 Jan;25(1):124-137. doi: 10.1007/s10120-021-01239-9. Epub 2021 Sep 05.

BACKGROUND: Tumour progression relies on the ability of cancer cells to penetrate and invade neighbouring tissues. E-cadherin loss is associated with increased cell invasion in gastric carcinoma, and germline mutations of the E-cadherin gene are causative of hereditary diffuse...

Cite
Figueiredo J, Ferreira RM, Xu H, et al. Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells. Gastric Cancer. 2021;25(1):124-137doi: 10.1007/s10120-021-01239-9.
Figueiredo, J., Ferreira, R. M., Xu, H., Gonçalves, M., Barros-Carvalho, A., Cravo, J., Maia, A. F., Carneiro, P., Figueiredo, C., Smith, M. L., Stamenović, D., Morais-de-Sá, E., & Seruca, R. (2022). Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 25(1), 124-137. https://doi.org/10.1007/s10120-021-01239-9
Figueiredo, Joana, et al. "Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells." Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association vol. 25,1 (2022): 124-137. doi: https://doi.org/10.1007/s10120-021-01239-9
Figueiredo J, Ferreira RM, Xu H, Gonçalves M, Barros-Carvalho A, Cravo J, Maia AF, Carneiro P, Figueiredo C, Smith ML, Stamenović D, Morais-de-Sá E, Seruca R. Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells. Gastric Cancer. 2022 Jan;25(1):124-137. doi: 10.1007/s10120-021-01239-9. Epub 2021 Sep 05. PMID: 34486077.
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Phlyctenular keratoconjunctivitis - an atypically severe case treated with systemic biologic immunosuppressive therapy.

GMS ophthalmology cases

Valério Sequeira Valadares J, Bastos-Carvalho A, Pedroso Franco JM, Mourão AF, Monteiro-Grillo M.
PMID: 27625937
GMS Ophthalmol Cases. 2014 Jan 10;4:Doc02. doi: 10.3205/oc000015. eCollection 2014.

PURPOSE: To report an atypically severe and refractory phlyctenular keratoconjunctivitis case treated successfully with systemic biologic immunosuppressive therapy.METHODS: A 10-year-old female was followed in the ophthalmology clinic for three years for a severe form of bilateral PKC. The patient...

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Valério Sequeira Valadares J, Bastos-Carvalho A, Pedroso Franco JM, et al. Phlyctenular keratoconjunctivitis - an atypically severe case treated with systemic biologic immunosuppressive therapy. GMS Ophthalmol Cases. 2014;4:Doc02doi: 10.3205/oc000015.
Valério Sequeira Valadares, J., Bastos-Carvalho, A., Pedroso Franco, J. M., Mourão, A. F., & Monteiro-Grillo, M. (2014). Phlyctenular keratoconjunctivitis - an atypically severe case treated with systemic biologic immunosuppressive therapy. GMS ophthalmology cases, 4Doc02. https://doi.org/10.3205/oc000015
Valério Sequeira Valadares, Joana, et al. "Phlyctenular keratoconjunctivitis - an atypically severe case treated with systemic biologic immunosuppressive therapy." GMS ophthalmology cases vol. 4 (2014): Doc02. doi: https://doi.org/10.3205/oc000015
Valério Sequeira Valadares J, Bastos-Carvalho A, Pedroso Franco JM, Mourão AF, Monteiro-Grillo M. Phlyctenular keratoconjunctivitis - an atypically severe case treated with systemic biologic immunosuppressive therapy. GMS Ophthalmol Cases. 2014 Jan 10;4:Doc02. doi: 10.3205/oc000015. eCollection 2014. PMID: 27625937; PMCID: PMC5015615.
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Human IgG1 antibodies suppress angiogenesis in a target-independent manner.

Signal transduction and targeted therapy

Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J.
PMID: 26918197
Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.1. Epub 2016 Jan 28.

Aberrant angiogenesis is implicated in diseases affecting nearly 10% of the world's population. The most widely used anti-angiogenic drug is bevacizumab, a humanized IgG1 monoclonal antibody that targets human VEGFA. Although bevacizumab does not recognize mouse Vegfa, it inhibits...

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Bogdanovich S, Kim Y, Mizutani T, et al. Human IgG1 antibodies suppress angiogenesis in a target-independent manner. Signal Transduct Target Ther. 2016;1doi: 10.1038/sigtrans.2015.1.
Bogdanovich, S., Kim, Y., Mizutani, T., Yasuma, R., Tudisco, L., Cicatiello, V., Bastos-Carvalho, A., Kerur, N., Hirano, Y., Baffi, J. Z., Tarallo, V., Li, S., Yasuma, T., Arpitha, P., Fowler, B. J., Wright, C. B., Apicella, I., Greco, A., Brunetti, A., Ruvo, M., Sandomenico, A., Nozaki, M., Ijima, R., Kaneko, H., Ogura, Y., Terasaki, H., Ambati, B. K., Leusen, J. H., Langdon, W. Y., Clark, M. R., Armour, K. L., Bruhns, P., Verbeek, J. S., Gelfand, B. D., De Falco, S., & Ambati, J. (2016). Human IgG1 antibodies suppress angiogenesis in a target-independent manner. Signal transduction and targeted therapy, 1. https://doi.org/10.1038/sigtrans.2015.1
Bogdanovich, Sasha, et al. "Human IgG1 antibodies suppress angiogenesis in a target-independent manner." Signal transduction and targeted therapy vol. 1 (2016). doi: https://doi.org/10.1038/sigtrans.2015.1
Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J. Human IgG1 antibodies suppress angiogenesis in a target-independent manner. Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.1. Epub 2016 Jan 28. PMID: 26918197; PMCID: PMC4763941.
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Showing 1 to 7 of 7 entries