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Showing 1 to 12 of 18 entries
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Soluble amyloid-beta isoforms predict downstream Alzheimer's disease pathology.

Cell & bioscience

Povala G, Bellaver B, De Bastiani MA, Brum WS, Ferreira PCL, Bieger A, Pascoal TA, Benedet AL, Souza DO, Araujo RM, Zatt B, Rosa-Neto P, Zimmer ER.
PMID: 34895338
Cell Biosci. 2021 Dec 11;11(1):204. doi: 10.1186/s13578-021-00712-3.

BACKGROUND: Changes in soluble amyloid-beta (Aβ) levels in cerebrospinal fluid (CSF) are detectable at early preclinical stages of Alzheimer's disease (AD). However, whether Aβ levels can predict downstream AD pathological features in cognitively unimpaired (CU) individuals remains unclear. With...

Antidepressant-Like Effects of Chronic Guanosine in the Olfactory Bulbectomy Mouse Model.

Frontiers in psychiatry

Almeida RF, Nonose Y, Ganzella M, Loureiro SO, Rocha A, Machado DG, Bellaver B, Fontella FU, Leffa DT, Pettenuzzo LF, Venturin GT, Greggio S, da Costa JC, Zimmer ER, Elisabetsky E, Souza DO.
PMID: 34421682
Front Psychiatry. 2021 Aug 04;12:701408. doi: 10.3389/fpsyt.2021.701408. eCollection 2021.

Major depressive disorder (MDD) leads to pervasive changes in the health of afflicted patients. Despite advances in the understanding of MDD and its treatment, profound innovation is needed to develop fast-onset antidepressants with higher effectiveness. When acutely administered, the...

An Optimized Dual Extraction Method for the Simultaneous and Accurate Analysis of Polar Metabolites and Lipids Carried out on Single Biological Samples.

Metabolites

Villaret-Cazadamont J, Poupin N, Tournadre A, Batut A, Gales L, Zalko D, Cabaton NJ, Bellvert F, Bertrand-Michel J.
PMID: 32825089
Metabolites. 2020 Aug 19;10(9). doi: 10.3390/metabo10090338.

The functional understanding of metabolic changes requires both a significant investigation into metabolic pathways, as enabled by global metabolomics and lipidomics approaches, and the comprehensive and accurate exploration of specific key pathways. To answer this pivotal challenge, we propose...

Strain specificity in the Myricaceae-Frankia symbiosis is correlated to plant root phenolics.

Functional plant biology : FPB

Popovici J, Walker V, Bertrand CD, Bellvert F, Fernandez MP, Comte G.
PMID: 32480923
Funct Plant Biol. 2011 Sep;38(9):682-689. doi: 10.1071/FP11144.

Plant secondary metabolites play an important role in the interaction between plants and their environment. For example, mutualistic nitrogen-fixing symbioses typically involve phenolic-based recognition between host plants and bacteria. Although these mechanisms are well studied in the rhizobia-legume symbiosis,...

Amyloid-dependent and amyloid-independent effects of Tau in individuals without dementia.

Annals of clinical and translational neurology

Therriault J, Pascoal TA, Sefranek M, Mathotaarachchi S, Benedet AL, Chamoun M, Lussier FZ, Tissot C, Bellaver B, Lukasewicz PS, Zimmer ER, Saha-Chaudhuri P, Gauthier S, Rosa-Neto P.
PMID: 34617688
Ann Clin Transl Neurol. 2021 Oct;8(10):2083-2092. doi: 10.1002/acn3.51457. Epub 2021 Oct 07.

OBJECTIVE: To investigate the relationship between the topography of amyloid-β plaques, tau neurofibrillary tangles, and the overlap between the two, with cognitive dysfunction in individuals without dementia.METHODS: We evaluated 154 individuals who were assessed with amyloid-β PET with [RESULTS:...

Correction to: Systemic Inflammation as a Driver of Brain Injury: the Astrocyte as an Emerging Player.

Molecular neurobiology

Bellaver B, Dos Santos JP, Leffa DT, Bobermin LD, Roppa RHA, da Silva Torres IL, Gonçalves CA, Souza DO, Quincozes-Santos A.
PMID: 32458387
Mol Neurobiol. 2020 Jul;57(7):3243. doi: 10.1007/s12035-020-01932-3.

The givenname "Paola" of the author Paola Haack Amaral Roppa (Roppa, P.H.A.) should be corrected to read Ricardo Haack Amaral Roppa (Roppa, R.H.A.) as presented above.

Soluble amyloid-beta isoforms predict downstream Alzheimer's disease pathology.

Cell & bioscience

Povala G, Bellaver B, De Bastiani MA, Brum WS, Ferreira PCL, Bieger A, Pascoal TA, Benedet AL, Souza DO, Araujo RM, Zatt B, Rosa-Neto P, Zimmer ER.
PMID: 34895338
Cell Biosci. 2021 Dec 11;11(1):204. doi: 10.1186/s13578-021-00712-3.

BACKGROUND: Changes in soluble amyloid-beta (Aβ) levels in cerebrospinal fluid (CSF) are detectable at early preclinical stages of Alzheimer's disease (AD). However, whether Aβ levels can predict downstream AD pathological features in cognitively unimpaired (CU) individuals remains unclear. With...

Author Correction: Effect of adding hydrochlorothiazide to usual treatment of patients with acute decompensated heart failure: a randomized clinical trial.

Scientific reports

Piardi DS, Butzke M, Mazzuca ACM, Gomes BS, Alves SG, Kotzian BJ, Ghisleni EC, Giaretta V, Bellaver P, Varaschin GA, Garbin AP, Beck-da-Silva L.
PMID: 34429503
Sci Rep. 2021 Aug 24;11(1):17370. doi: 10.1038/s41598-021-96943-y.

No abstract available.

Severe hepatopulmonary syndrome with hypoxemia refractory to liver transplant: Recovery after 67 days of ECMO support.

The International journal of artificial organs

Piltcher-da-Silva R, Chedid MF, Grezzana Filho TJM, Leipnitz I, de Araújo A, Gazzana MB, Saueressig MG, Lorenzi W, Cardoni MG, Bellaver P, Alvares-da-Silva MR, Feier FH, Chedid AD, Kruel CRP.
PMID: 33478326
Int J Artif Organs. 2022 Jan;45(1):121-123. doi: 10.1177/0391398821989067. Epub 2021 Jan 21.

Hepatopulmonary syndrome (HPS) is a complication of end stage liver disease (ESLD) and is manifested by severe hypoxemia, which usually responds to liver transplantation (LT). As compared to patients undergoing LT for other etiologies, patients with HPS present an...

Sink/Source Balance of Leaves Influences Amino Acid Pools and Their Associated Metabolic Fluxes in Winter Oilseed Rape (.

Metabolites

Dellero Y, Heuillet M, Marnet N, Bellvert F, Millard P, Bouchereau A.
PMID: 32295054
Metabolites. 2020 Apr 13;10(4). doi: 10.3390/metabo10040150.

Nitrogen remobilization processes from source to sink tissues in plants are determinant for seed yield and their implementation results in a complete reorganization of the primary metabolism during sink/source transition. Here, we decided to characterize the impact of the...

Engineering the Yeast .

Frontiers in bioengineering and biotechnology

Lajus S, Dusséaux S, Verbeke J, Rigouin C, Guo Z, Fatarova M, Bellvert F, Borsenberger V, Bressy M, Nicaud JM, Marty A, Bordes F.
PMID: 33195110
Front Bioeng Biotechnol. 2020 Oct 22;8:954. doi: 10.3389/fbioe.2020.00954. eCollection 2020.

Polylactic acid is a plastic polymer widely used in different applications from printing filaments for 3D printer to mulching films in agriculture, packaging materials, etc. Here, we report the production of poly-D-lactic acid (PDLA) in an engineered yeast strain...

Astrocyte Biomarkers in Alzheimer Disease: A Systematic Review and Meta-analysis.

Neurology

Bellaver B, Ferrari-Souza JP, Uglione da Ros L, Carter SF, Rodriguez-Vieitez E, Nordberg A, Pellerin L, Rosa-Neto P, Leffa DT, Zimmer ER.
PMID: 33952650
Neurology. 2021 May 05; doi: 10.1212/WNL.0000000000012109. Epub 2021 May 05.

OBJECTIVE: To perform a systematic review and meta-analysis to determine whether fluid and imaging astrocyte biomarkers are altered in Alzheimer's disease (AD).METHODS: PubMed and Web of Science databases were searched for articles reporting fluid or imaging astrocyte biomarkers in...

Showing 1 to 12 of 18 entries