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Showing 1 to 12 of 59 entries
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Association between the PPP3CC gene, coding for the calcineurin gamma catalytic subunit, and bipolar disorder.

Behavioral and brain functions : BBF

Mathieu F, Miot S, Etain B, El Khoury MA, Chevalier F, Bellivier F, Leboyer M, Giros B, Tzavara ET.
PMID: 18201382
Behav Brain Funct. 2008 Jan 17;4:2. doi: 10.1186/1744-9081-4-2.

BACKGROUND: Calcineurin is a neuron-enriched phosphatase that regulates synaptic plasticity and neuronal adaptation. Activation of calcineurin, overall, antagonizes the effects of the cyclic AMP activated protein/kinase A. Thus, kinase/phosphatase dynamic balance seems to be critical for transition to long-term...

A Nontoxic Transduction Enhancer Enables Highly Efficient Lentiviral Transduction of Primary Murine T Cells and Hematopoietic Stem Cells.

Molecular therapy. Methods & clinical development

Delville M, Soheili T, Bellier F, Durand A, Denis A, Lagresle-Peyrou C, Cavazzana M, Andre-Schmutz I, Six E.
PMID: 30191160
Mol Ther Methods Clin Dev. 2018 Aug 08;10:341-347. doi: 10.1016/j.omtm.2018.08.002. eCollection 2018 Sep 21.

Lentiviral vectors have emerged as an efficient, safe therapeutic tool for gene therapy based on hematopoietic stem cells (HSCs) or T cells. However, the monitoring of transduced cells in preclinical models remains challenging because of the inefficient transduction of...

The role of brain barriers in the neurokinetics and pharmacodynamics of lithium.

Pharmacological research

Luo H, Chevillard L, Bellivier F, Mégarbane B, Etain B, Cisternino S, Declèves X.
PMID: 33549730
Pharmacol Res. 2021 Apr;166:105480. doi: 10.1016/j.phrs.2021.105480. Epub 2021 Feb 04.

Lithium (Li) is the most widely used mood stabilizer in treating patients with bipolar disorder. However, more than half of the patients do not or partially respond to Li therapy, despite serum Li concentrations in the serum therapeutic range....

Recommendations of the treatment-resistant depression expert center network for promoting tobacco smoking cessation based on the results from the real-world FACE-TRD national cohort.

Progress in neuro-psychopharmacology & biological psychiatry

Korchia T, Faugere M, Suc N, Garosi A, Andrieu-Haller C, Breyton M, Godin O, Aouizerate B, Arbus C, Bennabi D, Bellivier F, Bougerol T, Camus V, Courtet P, Doumy O, El-Hage W, Genty JB, Haffen E, Holtzmann J, Horn M, Leboyer M, Llorca PM, Maruani J, Moirand R, Moliere F, Petrucci J, Rey R, Samalin L, Stephan F, Vaiva G, Walter M, Yrondi A, Boyer L, Lancon C, Richieri R, Fond G.
PMID: 34826559
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Nov 23;114:110479. doi: 10.1016/j.pnpbp.2021.110479. Epub 2021 Nov 23.

BACKGROUND: Tobacco smoking has been associated with suicide, impulsivity and depression in non-clinical populations with differences across sexes.OBJECTIVE: To determine the role of tobacco smoking in Treatment-Resistant Depression (TRD) according to sex in a precision-medicine approach.METHOD: The FACE-TRD cohort...

An evidence map of actigraphy studies exploring longitudinal associations between rest-activity rhythms and course and outcome of bipolar disorders.

International journal of bipolar disorders

Scott J, Colom F, Young A, Bellivier F, Etain B.
PMID: 33258017
Int J Bipolar Disord. 2020 Dec 01;8(1):37. doi: 10.1186/s40345-020-00200-6.

BACKGROUND: Evidence mapping is a structured approach used to synthesize the state-of-the-art in an emerging field of research when systematic reviews or meta-analyses are deemed inappropriate. We employed this strategy to summarise knowledge regarding longitudinal ecological monitoring of rest-activity...

Pharmacological treatment profiles in the FACE-BD cohort: Treatment description and complete data for bipolar subtypes.

Data in brief

Brodeur S, Terrisse H, Pouchon A, Godin O, Aouizerate B, Aubin V, Bellivier F, Belzeaux R, Bougerol T, Courtet P, Dubertret C, Gard S, Haffen E, Henry C, Leboyer M, Olié E, Roux P, Samalin L, Schwan R, Etain B, Bosson JL, Polosan M.
PMID: 33855141
Data Brief. 2021 Mar 25;36:107004. doi: 10.1016/j.dib.2021.107004. eCollection 2021 Jun.

In the current study, we provide the list of pharmacological interventions applied during the one-year follow-up period of the Pharmacological treatment profiles in the FACE-BD cohort study. These data show the treatments used in the new clusters formed in...

Misperception of sleep in bipolar disorder: an exploratory study using questionnaire versus actigraphy.

International journal of bipolar disorders

Ihler HM, Meyrel M, Hennion V, Maruani J, Gross G, Geoffroy PA, Lagerberg TV, Melle I, Bellivier F, Scott J, Etain B.
PMID: 33215273
Int J Bipolar Disord. 2020 Nov 20;8(1):34. doi: 10.1186/s40345-020-00198-x.

BACKGROUND: The concept of misperception of sleep refers to the estimated discrepancy between subjective and objective measures of sleep. This has been assessed only in a few prior studies in individuals with Bipolar Disorder (BD) as compared to Healthy...

Biomarkers to predict staging and treatment response in opioid dependence: A narrative review.

Drug development research

Vorspan F, Marie-Claire C, Bellivier F, Bloch V.
PMID: 33416203
Drug Dev Res. 2021 Aug;82(5):668-677. doi: 10.1002/ddr.21789. Epub 2021 Jan 08.

Opioid use disorder is a devastating disorder with a high burden in terms of overdose mortality, with an urgent need for more personalized prevention or therapeutic interventions. For this purpose, the description and validation of biological measures of staging...

Correction to: Using density of antecedent events and trajectory path analysis to investigate family-correlated patterns of onset of bipolar I disorder: a comparison of cohorts from Europe and USA.

International journal of bipolar disorders

Scott J, Vorspan F, Loftus J, Bellivier F, Etain B.
PMID: 34698968
Int J Bipolar Disord. 2021 Oct 26;9(1):32. doi: 10.1186/s40345-021-00242-4.

No abstract available.

Make lithium great again - Precisely!.

Bipolar disorders

Bellivier F, Young AH, Scott J, Etain B, Cousins DA.
PMID: 33098168
Bipolar Disord. 2021 Mar;23(2):209-210. doi: 10.1111/bdi.13023. Epub 2020 Nov 14.

No abstract available.

Handedness in bipolar disorders is associated with specific neurodevelopmental features: results of the BD-FACE cohort.

European archives of psychiatry and clinical neuroscience

Mallet J, Godin O, Mazer N, Le Strat Y, Bellivier F, Belzeaux R, Etain B, Fond G, Gard S, Henry C, Leboyer M, Llorca PM, Loftus J, Olié E, Passerieux C, Polosan M, Schwan R, Roux P, Dubertret C.
PMID: 34374842
Eur Arch Psychiatry Clin Neurosci. 2021 Aug 10; doi: 10.1007/s00406-021-01314-3. Epub 2021 Aug 10.

OBJECTIVES: High rates of non-right-handedness (NRH) and mixed-handedness exist in neurodevelopmental disorders. Dysfunctional neurodevelopmental pathways may be implicated in the underlying pathophysiology of bipolar disorders (BD), at least in some subgroups. Yet little is known about correlates of NRH...

Childhood maltreatment and metabolic syndrome in bipolar disorders: In search of moderators.

Psychoneuroendocrinology

Godin O, Gaube G, Olié E, Belzeaux R, Bellivier F, Loftus J, Courtet P, Dubertret C, Llorca PM, Gard S, Henry C, Schwan R, Passerieux C, Polosan M, Samalin L, Leboyer M, Etain B.
PMID: 34182249
Psychoneuroendocrinology. 2021 Sep;131:105327. doi: 10.1016/j.psyneuen.2021.105327. Epub 2021 Jun 15.

As compared to the general population, adult individuals with bipolar disorders (BD) have higher mortality rates due to cardiovascular diseases and higher prevalence of Metabolic Syndrome (MetS). Recent evidence suggests that childhood maltreatment may contribute to the cardiovascular burden...

Showing 1 to 12 of 59 entries