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Showing 1 to 12 of 101 entries
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Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS.

Neuron

Omura T, Omura K, Tedeschi A, Riva P, Painter MW, Rojas L, Martin J, Lisi V, Huebner EA, Latremoliere A, Yin Y, Barrett LB, Singh B, Lee S, Crisman T, Gao F, Li S, Kapur K, Geschwind DH, Kosik KS, Coppola G, He Z, Carmichael ST, Benowitz LI, Costigan M, Woolf CJ.
PMID: 27151643
Neuron. 2016 May 04;90(3):662. doi: 10.1016/j.neuron.2016.04.025.

No abstract available.

Acute Pancreatitis Related to a Chemotherapy Drug.

World journal of oncology

Murtaza G, Faqah A, Konowitz N, Lu H, Kuruvilla A, Adhikari S.
PMID: 28983380
World J Oncol. 2017 Feb;8(1):18-19. doi: 10.14740/wjon1006e. Epub 2017 Feb 23.

Drug-induced acute pancreatitis is a rare cause of pancreatitis. We present a case of pancreatitis caused by pazopanib, a tyrosine kinase inhibitor used in the treatment of renal cell carcinoma. A 57-year-old male with no risk factors for pancreatitis...

Analysis of the Phenotype of .

Frontiers in immunology

Riou C, Berkowitz N, Goliath R, Burgers WA, Wilkinson RJ.
PMID: 28848561
Front Immunol. 2017 Aug 10;8:968. doi: 10.3389/fimmu.2017.00968. eCollection 2017.

Several immune-based assays have been suggested to differentiate latent from active tuberculosis (TB). However, their relative performance as well as their efficacy in HIV-infected persons, a highly at-risk population, remains unclear. In a study of 81 individuals, divided into...

Nicotine and coronary heart disease.

Trends in cardiovascular medicine

Benowitz NL.
PMID: 21239286
Trends Cardiovasc Med. 1991 Dec;1(8):315-21. doi: 10.1016/1050-1738(91)90068-P.

Nicotine may contribute to accelerated atherogenesis by inducing hyperlipidemia, injuring endothelial cells, and/or promoting thrombosis, although the evidence is not conclusive. Nicotine is likely to contribute to acute ischemic events in people who already have coronary heart disease via...

Multi-Omic Analyses of Growth Cones at Different Developmental Stages Provides Insight into Pathways in Adult Neuroregeneration.

iScience

Chauhan MZ, Arcuri J, Park KK, Zafar MK, Fatmi R, Hackam AS, Yin Y, Benowitz L, Goldberg JL, Samarah M, Bhattacharya SK.
PMID: 32058951
iScience. 2020 Feb 21;23(2):100836. doi: 10.1016/j.isci.2020.100836. Epub 2020 Jan 14.

Growth cones (GCs) are structures associated with growing neurons. GC membrane expansion, which necessitates protein-lipid interactions, is critical to axonal elongation in development and in adult neuritogenesis. We present a multi-omic analysis that integrates proteomics and lipidomics data for...

Balfour et al. Respond.

American journal of public health

Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R.
PMID: 34936414
Am J Public Health. 2022 Jan;112(1):e5-e6. doi: 10.2105/AJPH.2021.306570.

No abstract available.

Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis.

ACS omega

Herrera NG, Morano NC, Celikgil A, Georgiev GI, Malonis RJ, Lee JH, Tong K, Vergnolle O, Massimi AB, Yen LY, Noble AJ, Kopylov M, Bonanno JB, Garrett-Thomson SC, Hayes DB, Bortz RH, Wirchnianski AS, Florez C, Laudermilch E, Haslwanter D, Fels JM, Dieterle ME, Jangra RK, Barnhill J, Mengotto A, Kimmel D, Daily JP, Pirofski LA, Chandran K, Brenowitz M, Garforth SJ, Eng ET, Lai JR, Almo SC.
PMID: 33458462
ACS Omega. 2020 Dec 21;6(1):85-102. doi: 10.1021/acsomega.0c03512. eCollection 2021 Jan 12.

Coronavirus disease 2019 (COVID-19) is a global health crisis caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and there is a critical need to produce large quantities of high-quality SARS-CoV-2 Spike (S) protein for use in...

A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications.

SLAS discovery : advancing life sciences R & D

Stacey P, Lithgow H, Lewell X, Konopacka A, Besley S, Green G, Whatling R, Law R, Röth S, Sapkota GP, Smith IED, Burley GA, Harling J, Benowitz AB, Queisser MA, Muelbaier M.
PMID: 34041938
SLAS Discov. 2021 Aug;26(7):885-895. doi: 10.1177/24725552211017517. Epub 2021 May 27.

Targeted protein degradation is an emerging new strategy for the modulation of intracellular protein levels with applications in chemical biology and drug discovery. One approach to enable this strategy is to redirect the ubiquitin-proteasome system to mark and degrade...

Balfour et al. Respond.

American journal of public health

Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R.
PMID: 34936419
Am J Public Health. 2022 Jan;112(1):e2-e3. doi: 10.2105/AJPH.2021.306555.

No abstract available.

A mixed effects model for analyzing area under the curve of longitudinally measured biomarkers with missing data.

Pharmaceutical statistics

Shi L, Hatsukami DK, Koopmeiners JS, Le CT, Benowitz NL, Donny EC, Luo X.
PMID: 34151513
Pharm Stat. 2021 Nov;20(6):1249-1264. doi: 10.1002/pst.2146. Epub 2021 Jun 20.

A simple approach for analyzing longitudinally measured biomarkers is to calculate summary measures such as the area under the curve (AUC) for each individual and then compare the mean AUC between treatment groups using methods such as t test....

Mouth Washing Impaired SARS-CoV-2 Detection in Saliva.

Diagnostics (Basel, Switzerland)

Costa MM, Benoit N, Tissot-Dupont H, Million M, Pradines B, Granjeaud S, Almeras L.
PMID: 34441446
Diagnostics (Basel). 2021 Aug 22;11(8). doi: 10.3390/diagnostics11081509.

BACKGROUND: A previous study demonstrated the performance of the SalivetteOBJECTIVES: The aim of the present work was to assess the concordance level of SARS-CoV-2 detection between paired sampling of NPSs and saliva collected with SalivetteRESULTS: A total of 319...

Absence of Association between Methylene Blue Reduced Susceptibility and Polymorphisms in 12 Genes Involved in Antimalarial Drug Resistance in African .

Pharmaceuticals (Basel, Switzerland)

Gendrot M, Delandre O, Robert MG, Foguim FT, Benoit N, Amalvict R, Fonta I, Mosnier J, Madamet M, Pradines B, Group OBOTFNRCFIMS.
PMID: 33918981
Pharmaceuticals (Basel). 2021 Apr 09;14(4). doi: 10.3390/ph14040351.

Half the human population is exposed to malaria.

Showing 1 to 12 of 101 entries