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Showing 1 to 12 of 13 entries
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Synthesis and Antimicrobial Activity of 6-Thioxo-6,7-dihydro-2H-[1,2,4]triazino[2,3-c]-quinazolin-2-one Derivatives.

Scientia pharmaceutica

Nosulenko IS, Voskoboynik OY, Berest GG, Safronyuk SL, Kovalenko SI, Kamyshnyi OM, Polishchuk NM, Sinyak RS, Katsev AV.
PMID: 25853063
Sci Pharm. 2014 Mar 24;82(3):483-500. doi: 10.3797/scipharm.1402-10. Print 2014.

Potassium 8-R(1)-9-R(2)-10-R(3)-3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazoline-6-thiolates 2.1-2.26 were synthesized via cyclocondensation of 6-R-3-(3-R(1)-4-R(2)-5-R(3)-aminophenyl)-1,2,4-triazin-5-ones 1.1-1.26 with carbon disulfide, potassium hydroxide, and ethanol or with potassium O-ethyl dithiocarbonate in 2-propanol. The corresponding thiones 3.1-3.26 were obtained by treatment of 2.1-2.26 with hydrochloric acid. It was...

Substituted 2-[(2-Oxo-2H-[1,2,4]triazino [2,3-c]quinazolin-6-yl)thio]acetamides with Thiazole and Thiadiazole Fragments: Synthesis, Physicochemical Properties, Cytotoxicity, and Anticancer Activity.

Scientia pharmaceutica

Kovalenko SI, Nosulenko IS, Voskoboynik AY, Berest GG, Antypenko LN, Antypenko AN, Katsev AM.
PMID: 23264935
Sci Pharm. 2012 Oct-Dec;80(4):837-65. doi: 10.3797/scipharm.1208-07. Epub 2012 Oct 04.

The series of novel N-R-2-[(3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazolin-6-yl)thio]acetamides with thiazole and thiadiazole fragments in a molecule were obtained by alkylation of potassium salts 1.1-1.4 by N-hetaryl-2-chloroacetamides and by aminolysis of activated acids 2.1-2.4 with N,N'-carbonyldiimidazole (CDI). The structures of compounds were determined...

Muscle-sparing aortic coarctation repair.

JTCVS techniques

Berset SG, Dave H, Balmer C, Nowacka A, Pfister R, Myers PO, Prêtre R.
PMID: 34317891
JTCVS Tech. 2020 May 17;3:249-256. doi: 10.1016/j.xjtc.2020.05.005. eCollection 2020 Sep.

OBJECTIVE: Surgery for aortic coarctation repair provides excellent hemodynamic results but may be complicated by musculoskeletal issues. The purpose of the study was to determine the midterm results of a muscle-sparing surgical approach to aortic coarctation repair, with special...

Proposed protocol for determination of photostability Part I: cosmetic UV filters.

International journal of cosmetic science

Berset G, Gonzenbach H, Christ R, Martin R, Deflandre A, Mascotto RE, Jolley JD, Lowell W, Pelzer R, Stiehm T.
PMID: 19245454
Int J Cosmet Sci. 1996 Aug;18(4):167-77. doi: 10.1111/j.1467-2494.1996.tb00145.x.

Synopsis The protocol described here has been developed to measure the stability of UV-B filters; a modified version is recommended for UV-A filters. It should be considered as a tool to predict the effectiveness remaining after exposure to UV-A...

The impact of the COVID-19 pandemic on UK medical education. A nationwide student survey.

Medical teacher

Tekkis NP, Rafi D, Brown S, Courtney A, Kawka M, Howell AM, McLean K, Gardiner M, Mavroveli S, Hutchinson P, Tekkis P, Wilkinson P, Sam AH, Savva N, Kontovounisios C, Tekkis N, Rafi D, Brown S, Courtney A, Kawka M, Howell A, McLean K, Gardiner M, Mavroveli S, Hutchinson P, Tekkis P, Wilkinson P, Sam AH, Savva N, Kontovounisios C, Tekkis N, Rafi D, Brown S, Courtney A, Kawka M, Howell A, McLean K, Gardiner M, Mavroveli S, Hutchinson P, Tekkis P, Wilkinson P, Sam AH, Savva N, Kontovounisios C, Tekkis N, Brown S, Kawka M, Mclean K, Savva N, Wilkinson P, Sam AH, Singal A, Chia C, Chia W, Ganesananthan S, Ooi SZY, Pengelly S, Wellington J, Mak S, Subbiah Ponniah H, Heyes A, Aberman I, Ahmed T, Al-Shamaa S, Appleton L, Arshad A, Awan H, Baig Q, Benedict K, Berkes S, Citeroni NL, Damani A, de Sancha A, Fisayo T, Gupta S, Haq M, Heer B, Jones A, Khan H, Kim H, Meiyalagan N, Miller G, Minta N, Mirza L, Mohamed F, Ramjan F, Read P, Soni L, Tailor V, Tas RN, Vorona M, Walker M, Winkler T, Bardon A, Acquaah J, Ball T, Bani W, Elmasry A, Hussein F, Kolluri M, Lusta H, Newman J, Nott M, Perwaiz MI, Rayner R, Shah A, Shaw I, Yu K, Cairns M, Clough R, Gaier S, Hirani D, Jeyapalan T, Li Y, Patel CR, Shabir H, Wang YA, Weatherhead A, Dhiran A, Renney O, Wells P, Ferguson S, Joyce A, Mergo A, Adebayo O, Ahmad J, Akande O, Ang G, Aniereobi E, Awasthi S, Banjoko A, Bates J, Chibada C, Clarke N, Craner I, Desai DD, Dixon K, Duffaydar HI, Kuti M, Mughal AZ, Nair D, Pham MC, Preest GG, Reid R, Sachdeva GS, Selvaratnam K, Sheikh J, Soran V, Stoney N, Wheatle M, Howarth K, Knapp-Wilson A, Lee KS, Mampitiya N, Masson C, McAlinden JJ, McGowan N, Parmar SC, Robinson B, Wahid S, Willis L, Risquet R, Adebayo A, Dhingra L, Kathiravelupillai S, Narayanan R, Soni J, Ghafourian P, Hounat A, Lennon KA, Abdi Mohamud M, Chou W, Chong L, Graham CJ, Piya S, Riad AM, Vennard S, Wang J, Kawar L, Maseland C, Myatt R, Tengku Saifudin TNS, Yong SQ, Douglas F, Ogbechie C, Sharma K, Zafar L, Bajomo MO, Byrne MHV, Obi C, Oluyomi DI, Patsalides MA, Rajananthanan A, Richardson G, Clarke A, Roxas A, Adeboye W, Argus L, McSweeney J, Rahman-Chowdhury M, Hettiarachchi DS, Masood MT, Antypas A, Thomas M, de Andres Crespo M, Zimmerman M, Dhillon A, Abraha S, Burton O, Jalal AHB, Bailey B, Casey A, Kathiravelupillai A, Missir E, Boult H, Campen D, Collins JM, Dulai S, Elhassan M, Foster Z, Horton E, Jones E, Mahapatra S, Nancarrow T, Nyamapfene T, Rimmer A, Robberstad M, Robson-Brown S, Saeed A, Sarwar Y, Taylor C, Vetere G, Whelan MK, Williams J, Zahid D, Chand C, Matthews M.
PMID: 34428109
Med Teach. 2021 Aug 24;1-2. doi: 10.1080/0142159X.2021.1962835. Epub 2021 Aug 24.

No abstract available.

Spontaneous Resolution of Post-Traumatic Direct Carotid-Cavernous Fistula.

Interventional neurology

Naragum V, Barest G, AbdalKader M, Cronk KM, Nguyen TN.
PMID: 29628938
Interv Neurol. 2018 Feb;7(1):1-5. doi: 10.1159/000480303. Epub 2017 Sep 27.

Post-traumatic carotid-cavernous fistulas are due to a tear in the wall of the cavernous carotid artery, leading to shunting of blood into the cavernous sinus. These are generally high-flow fistula and rarely resolve spontaneously. Most cases require endovascular embolization....

Preparation and biological properties of 2-thio-containing pyrimidines and their condensed analogs.

Chemistry of heterocyclic compounds

Voskoboynik OY, Kolomoets OS, Berest GG, Nosulenko IS, Martynenko YV, Kovalenko SI.
PMID: 32214419
Chem Heterocycl Compd (N Y). 2017;53(3):256-272. doi: 10.1007/s10593-017-2048-2. Epub 2017 Apr 27.

The known methods for synthesis of thioxopyrimidines and their condensed analogs with exocyclic sulfur atom are summarized and discussed. The most popular approaches are based on [3+3], [4+2], [5+1] cyclization processes or domino reactions. The literature data analysis shows...

Magnetic Resonance Spectroscopy of the Head and Neck: Principles, Applications, and Challenges.

Neuroimaging clinics of North America

Fujima N, Carlota Andreu-Arasa V, Barest GD, Srinivasan A, Sakai O.
PMID: 32600631
Neuroimaging Clin N Am. 2020 Aug;30(3):283-293. doi: 10.1016/j.nic.2020.04.006. Epub 2020 Jun 11.

Several investigations have revealed the utility of magnetic resonance spectroscopy (MRS) as an adjunct in the evaluation of lesions of the head and neck. This technique remains a challenge in the head and neck because of its low signal-to-noise...

Duplication of the Posterior Cerebral Artery and the 'True Fetal' Variant.

Interventional neurology

Masoud H, Nguyen TN, Thatcher J, Barest G, Norbash AM.
PMID: 26600800
Interv Neurol. 2015 Oct;4(1):64-7. doi: 10.1159/000437310. Epub 2015 Sep 18.

We present a rare case of bilateral posterior cerebral artery variant anatomy seen in a patient presenting with acute ischemic stroke. An embryological explanation of the variant configuration is discussed along with demonstrative radiologic images and a display of...

Validity of indirect assessment of writing competency for deaf and hard-of-hearing college students.

Journal of deaf studies and deaf education

Berent G, Samar V, Kelly R, Berent R, Bochner J, Albertini J, Sacken J.
PMID: 15579821
J Deaf Stud Deaf Educ. 1996;1(3):167-78. doi: 10.1093/oxfordjournals.deafed.a014292.

Indirect tests of writing competency are often used at the college level for a variety of educational, programmatic, and research purposes. Although such tests may have been validated on hearing populations, it cannot be assumed that they validly assess...

2-[(3-Aminoalkyl-(alkaryl-,aryl-))-.

Turkish journal of chemistry

Martynenko Y, Berest G, Bukhtiayrova N, Belenichev I, Voskoboinik O, Kovalenko S.
PMID: 33488191
Turk J Chem. 2020 Jun 01;44(3):746-755. doi: 10.3906/kim-2002-24. eCollection 2020.

The presented work is devoted to the development of synthesis methods for novel 2-[(3-aminoalkyl-(alkaryl-, aryl-))-1H-1,2,4-triazolo]anilines. Abovementioned compounds were obtained via hydrazinolysis (Ing-Manske procedure) and acid hydrolysis of corresponding N -acylated{([1,2,4]triazolo[1,5-c]quinazolin-2-yl)alkyl-(alkaryl-, aryl-)}amines. The regioselectivity of hydrazinolysis and hydrolysis were established....

Hydrophilic polymer embolization following flow diversion of cerebral aneurysms.

The neuroradiology journal

Abdalkader M, Sathya A, Ma A, Cervantes-Arslanian AM, Chung DY, Barest G, Nguyen TN.
PMID: 33765885
Neuroradiol J. 2021 Aug;34(4):363-369. doi: 10.1177/19714009211004185. Epub 2021 Mar 26.

Foreign body embolization is a rare and potentially under-recognized complication of neuroendovascular procedures. This complication should be considered in the differential diagnosis for clinical or radiological deterioration following neurovascular interventions. We report a case of foreign body hydrophilic coating...

Showing 1 to 12 of 13 entries