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Showing 1 to 12 of 33 entries
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The Mn(2+)/Mn(3+) state of La0.7Ce0.3MnO3 by oxygen reduction and photodoping.

Journal of physics. Condensed matter : an Institute of Physics journal

Thiessen A, Beyreuther E, Grafström S, Dörr K, Werner R, Kleiner R, Koelle D, Eng LM.
PMID: 24389924
J Phys Condens Matter. 2014 Jan 29;26(4):045502. doi: 10.1088/0953-8984/26/4/045502. Epub 2014 Jan 06.

Films of cerium-doped LaMnO3, which has been intensively discussed as an electron-doped counterpart to hole-doped mixed-valence lanthanum manganites during the past decade, were analyzed by x-ray photoemission spectroscopy with respect to their manganese valence under photoexcitation. The comparative analysis...

Spectral and spatial shaping of laser-driven proton beams using a pulsed high-field magnet beamline.

Scientific reports

Brack FE, Kroll F, Gaus L, Bernert C, Beyreuther E, Cowan TE, Karsch L, Kraft S, Kunz-Schughart LA, Lessmann E, Metzkes-Ng J, Obst-Huebl L, Pawelke J, Rehwald M, Schlenvoigt HP, Schramm U, Sobiella M, Szabó ER, Ziegler T, Zeil K.
PMID: 32499539
Sci Rep. 2020 Jun 04;10(1):9118. doi: 10.1038/s41598-020-65775-7.

Intense laser-driven proton pulses, inherently broadband and highly divergent, pose a challenge to established beamline concepts on the path to application-adapted irradiation field formation, particularly for 3D. Here we experimentally show the successful implementation of a highly efficient (50%...

Late Side Effects in Normal Mouse Brain Tissue After Proton Irradiation.

Frontiers in oncology

Suckert T, Beyreuther E, Müller J, Azadegan B, Meinhardt M, Raschke F, Bodenstein E, von Neubeck C, Lühr A, Krause M, Dietrich A.
PMID: 33520710
Front Oncol. 2021 Jan 11;10:598360. doi: 10.3389/fonc.2020.598360. eCollection 2020.

Radiation-induced late side effects such as cognitive decline and normal tissue complications can severely affect quality of life and outcome in long-term survivors of brain tumors. Proton therapy offers a favorable depth-dose deposition with the potential to spare tumor-surrounding...

Retinal Optical Coherence Tomography in Neuromyelitis Optica.

Neurology(R) neuroimmunology & neuroinflammation

Oertel FC, Specovius S, Zimmermann HG, Chien C, Motamedi S, Bereuter C, Cook L, Lana Peixoto MA, Fontanelle MA, Kim HJ, Hyun JW, Palace J, Roca-Fernandez A, Leite MI, Sharma S, Ashtari F, Kafieh R, Dehghani A, Pourazizi M, Pandit L, D'Cunha A, Aktas O, Ringelstein M, Albrecht P, May E, Tongco C, Leocani L, Pisa M, Radaelli M, Martinez-Lapiscina EH, Stiebel-Kalish H, Siritho S, de Seze J, Senger T, Havla J, Marignier R, Calvo AC, Bichuetti D, Tavares IM, Asgari N, Soelberg K, Altintas A, Yildirim R, Tanriverdi U, Jacob A, Huda S, Rimler Z, Reid A, Mao-Draayer Y, Soto de Castillo I, Petzold A, Green AJ, Yeaman MR, Smith T, Brandt AU, Paul F.
PMID: 34526385
Neurol Neuroimmunol Neuroinflamm. 2021 Sep 15;8(6). doi: 10.1212/NXI.0000000000001068. Print 2021 Nov.

BACKGROUND AND OBJECTIVES: To determine optic nerve and retinal damage in aquaporin-4 antibody (AQP4-IgG)-seropositive neuromyelitis optica spectrum disorders (NMOSD) in a large international cohort after previous studies have been limited by small and heterogeneous cohorts.METHODS: The cross-sectional Collaborative Retrospective...

Amyloid Abeta levels in Alzheimer's disease - A diagnostic tool and the key to understanding the natural history of Abeta?.

Journal of Alzheimer's disease : JAD

McLean CA, Beyreuther K, Masters CL.
PMID: 12214051
J Alzheimers Dis. 2001 Jun;3(3):305-312. doi: 10.3233/jad-2001-3305.

The biogenesis and degradation/clearance of Abeta amyloid lies at the centre of the pathogenesis of Alzheimer's disease. Quantification of the various metabolic pools of Abeta in the brains and in the periphery may aid in diagnosis, prognosis and the...

Leadless Dual-Chamber Pacing: A Novel Communication Method for Wireless Pacemaker Synchronization.

JACC. Basic to translational science

Bereuter L, Gysin M, Kueffer T, Kucera M, Niederhauser T, Fuhrer J, Heinisch P, Zurbuchen A, Obrist D, Tanner H, Haeberlin A.
PMID: 30623141
JACC Basic Transl Sci. 2018 Dec 31;3(6):813-823. doi: 10.1016/j.jacbts.2018.07.009. eCollection 2018 Dec.

Contemporary leadless pacemakers only feature single-chamber pacing capability. This study presents a prototype of a leadless dual-chamber pacemaker. Highly energy-efficient intrabody communication was implemented for wireless pacemaker synchronization. Optimal communication parameters were obtained by in vivo and ex vivo...

Applying Tissue Slice Culture in Cancer Research-Insights from Preclinical Proton Radiotherapy.

Cancers

Suckert T, Rassamegevanon T, Müller J, Dietrich A, Graja A, Reiche M, Löck S, Krause M, Beyreuther E, von Neubeck C.
PMID: 32560230
Cancers (Basel). 2020 Jun 16;12(6). doi: 10.3390/cancers12061589.

A challenge in cancer research is the definition of reproducible, reliable, and practical models, which reflect the effects of complex treatment modalities and the heterogeneous response of patients. Proton beam radiotherapy (PBRT), relative to conventional photon-based radiotherapy, offers the...

Functionally Relevant Maculopathy and Optic Atrophy in Spinocerebellar Ataxia Type 1.

Movement disorders clinical practice

Oertel FC, Zeitz O, Rönnefarth M, Bereuter C, Motamedi S, Zimmermann HG, Kuchling J, Grosch AS, Doss S, Browne A, Paul F, Schmitz-Hübsch T, Brandt AU.
PMID: 32626794
Mov Disord Clin Pract. 2020 May 06;7(5):502-508. doi: 10.1002/mdc3.12949. eCollection 2020 Jul.

BACKGROUND: Spinocerebellar ataxia type 1 (SCA-ATXN1) is an inherited progressive ataxia disorder characterized by an adult-onset cerebellar syndrome combined with nonataxia signs. Retinal or optic nerve affection are not systematically described.OBJECTIVES: To describe a retinal phenotype and its functional...

Cowpea mosaic virus VPg: sequencing of radiochemically modified protein allows mapping of the gene on B RNA.

The EMBO journal

Zabel P, Moerman M, Lomonossoff G, Shanks M, Beyreuther K.
PMID: 16453534
EMBO J. 1984 Jul;3(7):1629-34.

A partial amino acid sequence of cowpea mosaic virus (CPMV) VPg radiochemically modified by chloramine-T and Bolton-Hunter reagent has been determined. VPg covalently bound to viral RNA chains (VPg-RNA) was iodinated with chloramine-T and Bolton-Hunter reagent to label tyrosine...

Comparative Proton and Photon Irradiation Combined with Pharmacological Inhibitors in 3D Pancreatic Cancer Cultures.

Cancers

Görte J, Beyreuther E, Danen EHJ, Cordes N.
PMID: 33142778
Cancers (Basel). 2020 Oct 31;12(11). doi: 10.3390/cancers12113216.

Pancreatic ductal adenocarcinoma (PDAC) is a highly therapy-resistant tumor entity of unmet needs. Over the last decades, radiotherapy has been considered as an additional treatment modality to surgery and chemotherapy. Owing to radiosensitive abdominal organs, high-precision proton beam radiotherapy...

Astrocytic outer retinal layer thinning is not a feature in AQP4-IgG seropositive neuromyelitis optica spectrum disorders.

Journal of neurology, neurosurgery, and psychiatry

Lu A, Zimmermann HG, Specovius S, Motamedi S, Chien C, Bereuter C, Lana-Peixoto MA, Fontenelle MA, Ashtari F, Kafieh R, Dehghani A, Pourazizi M, Pandit L, D'Cunha A, Kim HJ, Hyun JW, Jung SK, Leocani L, Pisa M, Radaelli M, Siritho S, May EF, Tongco C, De Sèze J, Senger T, Palace J, Roca-Fernández A, Leite MI, Sharma SM, Stiebel-Kalish H, Asgari N, Soelberg KK, Martinez-Lapiscina EH, Havla J, Mao-Draayer Y, Rimler Z, Reid A, Marignier R, Cobo-Calvo A, Altintas A, Tanriverdi U, Yildirim R, Aktas O, Ringelstein M, Albrecht P, Tavares IM, Bichuetti DB, Jacob A, Huda S, Soto de Castillo I, Petzold A, Green AJ, Yeaman MR, Smith TJ, Cook L, Paul F, Brandt AU, Oertel FC.
PMID: 34711650
J Neurol Neurosurg Psychiatry. 2021 Oct 28; doi: 10.1136/jnnp-2021-327412. Epub 2021 Oct 28.

BACKGROUND: Patients with anti-aquaporin-4 antibody seropositive (AQP4-IgG+) neuromyelitis optica spectrum disorders (NMOSDs) frequently suffer from optic neuritis (ON) leading to severe retinal neuroaxonal damage. Further, the relationship of this retinal damage to a primary astrocytopathy in NMOSD is uncertain....

Optical-field driven charge-transfer modulations near composite nanostructures.

Nature communications

Lee KJ, Beyreuther E, Jalil SA, Kim SJ, Eng LM, Guo C, André P.
PMID: 33262344
Nat Commun. 2020 Dec 01;11(1):6150. doi: 10.1038/s41467-020-19423-3.

Optical activation of material properties illustrates the potentials held by tuning light-matter interactions with impacts ranging from basic science to technological applications. Here, we demonstrate for the first time that composite nanostructures providing nonlocal environments can be engineered to...

Showing 1 to 12 of 33 entries