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Showing 1 to 6 of 6 entries
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The Impact of the Ubiquitin System in the Pathogenesis of Squamous Cell Carcinomas.

Cancers

Gatti V, Bernassola F, Talora C, Melino G, Peschiaroli A.
PMID: 32560247
Cancers (Basel). 2020 Jun 16;12(6). doi: 10.3390/cancers12061595.

The ubiquitin system is a dynamic regulatory pathway controlling the activity, subcellular localization and stability of a myriad of cellular proteins, which in turn affects cellular homeostasis through the regulation of a variety of signaling cascades. Aberrant activity of...

Induction of apoptosis by IFNγ in human neuroblastoma cell lines through the CD95/CD95L autocrine circuit.

Cell death and differentiation

Bernassola F, Scheuerpflug C, Herr I, Krammer PH, Debatin KM, Melino G.
PMID: 26256517
Cell Death Differ. 2015 Sep;22(9):1562. doi: 10.1038/cdd.2015.89.

No abstract available.

Correlation between primary headaches and learning disabilities in children and adolescents.

Minerva pediatrics

Onofri A, Olivieri L, Silva P, Bernassola M, Tozzi E.
PMID: 33858130
Minerva Pediatr (Torino). 2021 Apr 15; doi: 10.23736/S2724-5276.21.06191-7. Epub 2021 Apr 15.

BACKGROUND: Primary Headaches (H) and Learning Disabilities (LD) are frequent in childhood and can coexist in the same subject, but their correlation is not always clear. Aim of our study is to evaluate these relationship considering also any psychopathologies...

The receptor super-antagonist Sant7.

Oncology reports

Savino R, Demartis A, Ciapponi L, Sporeno E, Toniatti C, Bernassola F, Melino G, Klein B, Ciliberto G.
PMID: 21590082
Oncol Rep. 1997 May-Jun;4(3):485-92. doi: 10.3892/or.4.3.485.

Interleukin-6 (IL-6) plays a central role in the pathogenesis of multiple myeloma, acting both as a growth and a survival factor for myeloma cells. IL-6 has been recently shown to possess three topologically distinct receptor binding sites: site 1...

Emerging roles of long non-coding RNAs in breast cancer biology and management.

Seminars in cancer biology

Amelio I, Bernassola F, Candi E.
PMID: 32619506
Semin Cancer Biol. 2021 Jul;72:36-45. doi: 10.1016/j.semcancer.2020.06.019. Epub 2020 Jun 30.

Breast cancer is the most common cancer in women with the highest mortality among this gender. Despite treatment strategies including surgery, hormone therapy and targeted therapy have recently advanced, innovative biomarkers are needed for the early detection, treatment and...

Emerging roles of long non-coding RNAs in breast cancer biology and management.

Seminars in cancer biology

Amelio I, Bernassola F, Candi E.
PMID: 32619506
Semin Cancer Biol. 2021 Jul;72:36-45. doi: 10.1016/j.semcancer.2020.06.019. Epub 2020 Jun 30.

Breast cancer is the most common cancer in women with the highest mortality among this gender. Despite treatment strategies including surgery, hormone therapy and targeted therapy have recently advanced, innovative biomarkers are needed for the early detection, treatment and...

Showing 1 to 6 of 6 entries