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Showing 1 to 12 of 103 entries
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Problem structuring and multiple criteria decision analysis

Science interventions

Belton V, Stewart T.
GSID: PKPLT310cN0J
V Belton, T Stewart - Trends in multiple criteria decision analysis, 2010 - Springer

This chapter addresses two complementary themes in relation to problem structuring and MCDA. The first and primary theme highlights the nature and importance of problem …

Okul öncesi öğretmen ve öğretmen adaylarının okul öncesi öğretmen yetiştirme lisans programı hakkında görüş ve önerileri

Undergraduate training programs stem

Bartan M.
GSID: czD9_2ZpOfUJ
M Bartan - Dumlupınar Üniversitesi Eğitim Bilimleri Enstitüsü …, 2019 - dergipark.org.tr

… about the pre-school teacher training undergraduate program. In this study, descriptive … dersi çocukları tanıma teknikleri kodlama stem okul öncesinde ölçme değerlendirme değerler …

Extraspinal sacrococcygeal ependymoma masquerading as sacrococcygeal teratoma in the pediatric patient.

Pediatric surgery international

Amin R, Berdan E, Knipstein J, Jarzembowski J, Siddiqui S.
PMID: 29138922
Pediatr Surg Int. 2018 Jan;34(1):109-112. doi: 10.1007/s00383-017-4214-0. Epub 2017 Nov 14.

No abstract available.

WAH-1/AIF regulates mitochondrial oxidative phosphorylation in the nematode .

Cell death discovery

Troulinaki K, Büttner S, Marsal Cots A, Maida S, Meyer K, Bertan F, Gioran A, Piazzesi A, Fornarelli A, Nicotera P, Bano D.
PMID: 29531799
Cell Death Discov. 2018 Jan 29;4:2. doi: 10.1038/s41420-017-0005-6. eCollection 2018 Dec.

Impaired mitochondrial energy metabolism contributes to a wide range of pathologic conditions, including neurodegenerative diseases. Mitochondrial apoptosis-inducing factor (AIF) is required for the correct maintenance of mitochondrial electron transport chain. An emerging body of clinical evidence indicates that several...

Catalytic Reduction of Nitrous Oxide by the Low-Symmetry Pt.

The journal of physical chemistry. A

Hernández E, Bertin V, Soto J, Miralrio A, Castro M.
PMID: 29437397
J Phys Chem A. 2018 Mar 01;122(8):2209-2220. doi: 10.1021/acs.jpca.7b11055. Epub 2018 Feb 21.

The search for a catalyst for the reduction of nitrous oxide (N

Therapeutic Drug Monitoring in the Era of Precision Medicine: Achievements, Gaps, and Perspectives-An Interview in Honor of Professor Charles Pippenger.

Therapeutic drug monitoring

Wong SH, Marquet P, Cattaneo D, Svinarov D, Bergan S, Walson P, Vinks AA, Shipkova M.
PMID: 34654029
Ther Drug Monit. 2021 Dec 01;43(6):719-727. doi: 10.1097/FTD.0000000000000932.

No abstract available.

Deletion of lysophosphatidylcholine acyltransferase 3 in myeloid cells worsens hepatic steatosis after a high-fat diet.

Journal of lipid research

Bourgeois T, Jalil A, Thomas C, Magnani C, Le Guern N, Gautier T, Pais de Barros JP, Bergas V, Choubley H, Mazzeo L, Menegaut L, Josiane Lebrun L, Van Dongen K, Xolin M, Jourdan T, Buch C, Labbé J, Saas P, Lagrost L, Masson D, Grober J.
PMID: 33518513
J Lipid Res. 2020 Dec 17;62:100013. doi: 10.1194/jlr.RA120000737. Epub 2020 Dec 17.

Recent studies have highlighted an important role for lysophosphatidylcholine acyltransferase 3 (LPCAT3) in controlling the PUFA composition of cell membranes in the liver and intestine. In these organs, LPCAT3 critically supports cell-membrane-associated processes such as lipid absorption or lipoprotein...

Revealing the Distribution of Metal Carboxylates in Oil Paint from the Micro- to Nanoscale.

Angewandte Chemie (International ed. in English)

Ma X, Beltran V, Ramer G, Pavlidis G, Parkinson DY, Thoury M, Meldrum T, Centrone A, Berrie BH.
PMID: 31226237
Angew Chem Int Ed Engl. 2019 Aug 19;58(34):11652-11656. doi: 10.1002/anie.201903553. Epub 2019 Jul 24.

Oil paints comprise pigments, drying oils, and additives that together confer desirable properties, but can react to form metal carboxylates (soaps) that may damage artworks over time. To obtain information on soap formation and aggregation, we introduce a new...

HER3 Is an Actionable Target in Advanced Prostate Cancer.

Cancer research

Gil V, Miranda S, Riisnaes R, Gurel B, D'Ambrosio M, Vasciaveo A, Crespo M, Ferreira A, Brina D, Troiani M, Sharp A, Sheehan B, Christova R, Seed G, Figueiredo I, Lambros M, Dolling D, Rekowski J, Alajati A, Clarke M, Pereira R, Flohr P, Fowler G, Boysen G, Sumanasuriya S, Bianchini D, Rescigno P, Aversa C, Tunariu N, Guo C, Paschalis A, Bertan C, Buroni L, Ning J, Carreira S, Workman P, Swain A, Califano A, Shen MM, Alimonti A, Neeb A, Welti J, Yuan W, de Bono J.
PMID: 34753775
Cancer Res. 2021 Dec 15;81(24):6207-6218. doi: 10.1158/0008-5472.CAN-21-3360. Epub 2021 Nov 09.

It has been recognized for decades that ERBB signaling is important in prostate cancer, but targeting ERBB receptors as a therapeutic strategy for prostate cancer has been ineffective clinically. However, we show here that membranous HER3 protein is commonly...

Quantification of Lung Fibrosis in IPF-Like Mouse Model and Pharmacological Response to Treatment by Micro-Computed Tomography.

Frontiers in pharmacology

Ruscitti F, Ravanetti F, Bertani V, Ragionieri L, Mecozzi L, Sverzellati N, Silva M, Ruffini L, Menozzi V, Civelli M, Villetti G, Stellari FF.
PMID: 32792953
Front Pharmacol. 2020 Jul 21;11:1117. doi: 10.3389/fphar.2020.01117. eCollection 2020.

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive degenerative lung disease leading to respiratory failure and death. Although anti-fibrotic drugs are now available for treating IPF, their clinical efficacy is limited and lung transplantation remains the only modality to...

The Master Observational Trial: A New Class of Master Protocol to Advance Precision Medicine.

Cell

Dickson D, Johnson J, Bergan R, Owens R, Subbiah V, Kurzrock R.
PMID: 31951522
Cell. 2020 Jan 09;180(1):9-14. doi: 10.1016/j.cell.2019.12.009.

This commentary introduces a new clinical trial construct, the Master Observational Trial (MOT), which hybridizes the power of molecularly based master interventional protocols with the breadth of real-world data. The MOT provides a clinical venue to allow molecular medicine...

Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial.

Cancer discovery

Carreira S, Porta N, Arce-Gallego S, Seed G, Llop-Guevara A, Bianchini D, Rescigno P, Paschalis A, Bertan C, Baker C, Goodall J, Miranda S, Riisnaes R, Figueiredo I, Ferreira A, Pereira R, Crespo M, Gurel B, Nava Rodrigues D, Pettitt SJ, Yuan W, Serra V, Rekowski J, Lord CJ, Hall E, Mateo J, de Bono JS.
PMID: 34045297
Cancer Discov. 2021 Nov;11(11):2812-2827. doi: 10.1158/2159-8290.CD-21-0007. Epub 2021 May 27.

PARP inhibitors are approved for treating advanced prostate cancers (APC) with various defective DNA repair genes; however, further studies to clinically qualify predictive biomarkers are warranted. Herein we analyzed TOPARP-B phase II clinical trial samples, evaluating whole-exome and low-pass...

Showing 1 to 12 of 103 entries