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Label-free fluorescence detection of aromatic compounds in chip electrophoresis applying two-photon excitation and time-correlated single-photon counting.

Analytical chemistry

Beyreiss R, Geißler D, Ohla S, Nagl S, Posch TN, Belder D.
PMID: 23944704
Anal Chem. 2013 Sep 03;85(17):8150-7. doi: 10.1021/ac4010937. Epub 2013 Aug 22.

In this study, we introduce time-resolved fluorescence detection with two-photon excitation at 532 nm for label-free analyte determination in microchip electrophoresis. In the developed method, information about analyte fluorescence lifetimes is collected by time-correlated single-photon counting, improving reliable peak...

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Beyreiss R, Geißler D, Ohla S, et al. Label-free fluorescence detection of aromatic compounds in chip electrophoresis applying two-photon excitation and time-correlated single-photon counting. Anal Chem. 2013;85(17):8150-7doi: 10.1021/ac4010937.
Beyreiss, R., Geißler, D., Ohla, S., Nagl, S., Posch, T. N., & Belder, D. (2013). Label-free fluorescence detection of aromatic compounds in chip electrophoresis applying two-photon excitation and time-correlated single-photon counting. Analytical chemistry, 85(17), 8150-7. https://doi.org/10.1021/ac4010937
Beyreiss, Reinhild, et al. "Label-free fluorescence detection of aromatic compounds in chip electrophoresis applying two-photon excitation and time-correlated single-photon counting." Analytical chemistry vol. 85,17 (2013): 8150-7. doi: https://doi.org/10.1021/ac4010937
Beyreiss R, Geißler D, Ohla S, Nagl S, Posch TN, Belder D. Label-free fluorescence detection of aromatic compounds in chip electrophoresis applying two-photon excitation and time-correlated single-photon counting. Anal Chem. 2013 Sep 03;85(17):8150-7. doi: 10.1021/ac4010937. Epub 2013 Aug 22. PMID: 23944704.
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HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer.

Cancers

Mayr C, Kiesslich T, Erber S, Bekric D, Dobias H, Beyreis M, Ritter M, Jäger T, Neumayer B, Winkelmann P, Klieser E, Neureiter D.
PMID: 34359763
Cancers (Basel). 2021 Jul 31;13(15). doi: 10.3390/cancers13153862.

Inhibition of histone deacetylases (HDACs) is a promising anti-cancer approach. For biliary tract cancer (BTC), only limited therapeutic options are currently available. Therefore, we performed a comprehensive investigation of HDAC expression and pharmacological HDAC inhibition into a panel of...

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Mayr C, Kiesslich T, Erber S, et al. HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer. Cancers (Basel). 2021;13(15)doi: 10.3390/cancers13153862.
Mayr, C., Kiesslich, T., Erber, S., Bekric, D., Dobias, H., Beyreis, M., Ritter, M., Jäger, T., Neumayer, B., Winkelmann, P., Klieser, E., & Neureiter, D. (2021). HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer. Cancers, 13(15), . https://doi.org/10.3390/cancers13153862
Mayr, Christian, et al. "HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer." Cancers vol. 13,15 (2021). doi: https://doi.org/10.3390/cancers13153862
Mayr C, Kiesslich T, Erber S, Bekric D, Dobias H, Beyreis M, Ritter M, Jäger T, Neumayer B, Winkelmann P, Klieser E, Neureiter D. HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer. Cancers (Basel). 2021 Jul 31;13(15). doi: 10.3390/cancers13153862. PMID: 34359763; PMCID: PMC8345689.
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[Diagnosis and treatment of chronic inflammatory intestinal diseases. 2. Crohn disease].

Kinderarztliche Praxis

Beyreiss K, Bannert N, Cario WR, Fiehring C, Grävinghoff J, Jung G, Schmutzler S, Scholz H, Tambor U.
PMID: 6656097
Kinderarztl Prax. 1983 Oct;51(10):480-6.

No abstract available.

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Beyreiss K, Bannert N, Cario WR, et al. Diagnose und Therapie chronisch entzündlicher Darmerkrankungen. Teil 2: Morbus CROHN. [Diagnosis and treatment of chronic inflammatory intestinal diseases. 2. Crohn disease]. Kinderarztl Prax. 1983;51(10):480-6
Beyreiss, K., Bannert, N., Cario, W. R., Fiehring, C., Grävinghoff, J., Jung, G., Schmutzler, S., Scholz, H., & Tambor, U. (1983). Diagnose und Therapie chronisch entzündlicher Darmerkrankungen. Teil 2: Morbus CROHN. [Diagnosis and treatment of chronic inflammatory intestinal diseases. 2. Crohn disease]. Kinderarztliche Praxis, 51(10), 480-6.
Beyreiss, K, et al. "Diagnose und Therapie chronisch entzündlicher Darmerkrankungen. Teil 2: Morbus CROHN." [Diagnosis and treatment of chronic inflammatory intestinal diseases. 2. Crohn disease]. Kinderarztliche Praxis vol. 51,10 (1983): 480-6.
Beyreiss K, Bannert N, Cario WR, Fiehring C, Grävinghoff J, Jung G, Schmutzler S, Scholz H, Tambor U. Diagnose und Therapie chronisch entzündlicher Darmerkrankungen. Teil 2: Morbus CROHN. [Diagnosis and treatment of chronic inflammatory intestinal diseases. 2. Crohn disease]. Kinderarztl Prax. 1983 Oct;51(10):480-6. German. PMID: 6656097.
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The Cancer Stem Cell Inhibitor Napabucasin (BBI608) Shows General Cytotoxicity in Biliary Tract Cancer Cells and Reduces Cancer Stem Cell Characteristics.

Cancers

Beyreis M, Gaisberger M, Jakab M, Neureiter D, Helm K, Ritter M, Kiesslich T, Mayr C.
PMID: 30813586
Cancers (Basel). 2019 Feb 26;11(3). doi: 10.3390/cancers11030276.

Biliary tract cancer is a devastating disease with limited therapeutic options. The involvement of cancer stem cells in biliary tract cancer is likely. Napabucasin is a previously described cancer stem cell inhibitor that is currently being used in clinical...

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Beyreis M, Gaisberger M, Jakab M, et al. The Cancer Stem Cell Inhibitor Napabucasin (BBI608) Shows General Cytotoxicity in Biliary Tract Cancer Cells and Reduces Cancer Stem Cell Characteristics. Cancers (Basel). 2019;11(3)doi: 10.3390/cancers11030276.
Beyreis, M., Gaisberger, M., Jakab, M., Neureiter, D., Helm, K., Ritter, M., Kiesslich, T., & Mayr, C. (2019). The Cancer Stem Cell Inhibitor Napabucasin (BBI608) Shows General Cytotoxicity in Biliary Tract Cancer Cells and Reduces Cancer Stem Cell Characteristics. Cancers, 11(3), . https://doi.org/10.3390/cancers11030276
Beyreis, Marlena, et al. "The Cancer Stem Cell Inhibitor Napabucasin (BBI608) Shows General Cytotoxicity in Biliary Tract Cancer Cells and Reduces Cancer Stem Cell Characteristics." Cancers vol. 11,3 (2019). doi: https://doi.org/10.3390/cancers11030276
Beyreis M, Gaisberger M, Jakab M, Neureiter D, Helm K, Ritter M, Kiesslich T, Mayr C. The Cancer Stem Cell Inhibitor Napabucasin (BBI608) Shows General Cytotoxicity in Biliary Tract Cancer Cells and Reduces Cancer Stem Cell Characteristics. Cancers (Basel). 2019 Feb 26;11(3). doi: 10.3390/cancers11030276. PMID: 30813586; PMCID: PMC6468451.
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Rapid prototyping of electrochromatography chips for improved two-photon excited fluorescence detection.

Analytical chemistry

Hackl C, Beyreiss R, Geissler D, Jezierski S, Belder D.
PMID: 24666258
Anal Chem. 2014 Apr 15;86(8):3773-9. doi: 10.1021/ac500793e. Epub 2014 Apr 07.

In the present study, we introduce two-photon excitation at 532 nm for label-free fluorescence detection in chip electrochromatography. Two-photon excitation at 532 nm offers a promising alternative to one-photon excitation at 266 nm, as it enables the use of...

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Hackl C, Beyreiss R, Geissler D, et al. Rapid prototyping of electrochromatography chips for improved two-photon excited fluorescence detection. Anal Chem. 2014;86(8):3773-9doi: 10.1021/ac500793e.
Hackl, C., Beyreiss, R., Geissler, D., Jezierski, S., & Belder, D. (2014). Rapid prototyping of electrochromatography chips for improved two-photon excited fluorescence detection. Analytical chemistry, 86(8), 3773-9. https://doi.org/10.1021/ac500793e
Hackl, Claudia, et al. "Rapid prototyping of electrochromatography chips for improved two-photon excited fluorescence detection." Analytical chemistry vol. 86,8 (2014): 3773-9. doi: https://doi.org/10.1021/ac500793e
Hackl C, Beyreiss R, Geissler D, Jezierski S, Belder D. Rapid prototyping of electrochromatography chips for improved two-photon excited fluorescence detection. Anal Chem. 2014 Apr 15;86(8):3773-9. doi: 10.1021/ac500793e. Epub 2014 Apr 07. PMID: 24666258.
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Monitoring on-chip Pictet-Spengler reactions by integrated analytical separation and label-free time-resolved fluorescence.

Chemistry (Weinheim an der Bergstrasse, Germany)

Ohla S, Beyreiss R, Fritzsche S, Glaser P, Nagl S, Stockhausen K, Schneider C, Belder D.
PMID: 22179940
Chemistry. 2012 Jan 23;18(4):1240-6. doi: 10.1002/chem.201101768. Epub 2011 Dec 16.

High-throughput screening for optimal reaction conditions and the search for efficient catalysts is of eminent importance in the development of chemical processes and for expanding the spectrum of synthetic methodologies in chemistry. In this context we report a novel...

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Ohla S, Beyreiss R, Fritzsche S, et al. Monitoring on-chip Pictet-Spengler reactions by integrated analytical separation and label-free time-resolved fluorescence. Chemistry. 2011;18(4):1240-6doi: 10.1002/chem.201101768.
Ohla, S., Beyreiss, R., Fritzsche, S., Glaser, P., Nagl, S., Stockhausen, K., Schneider, C., & Belder, D. (2012). Monitoring on-chip Pictet-Spengler reactions by integrated analytical separation and label-free time-resolved fluorescence. Chemistry (Weinheim an der Bergstrasse, Germany), 18(4), 1240-6. https://doi.org/10.1002/chem.201101768
Ohla, Stefan, et al. "Monitoring on-chip Pictet-Spengler reactions by integrated analytical separation and label-free time-resolved fluorescence." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 18,4 (2012): 1240-6. doi: https://doi.org/10.1002/chem.201101768
Ohla S, Beyreiss R, Fritzsche S, Glaser P, Nagl S, Stockhausen K, Schneider C, Belder D. Monitoring on-chip Pictet-Spengler reactions by integrated analytical separation and label-free time-resolved fluorescence. Chemistry. 2012 Jan 23;18(4):1240-6. doi: 10.1002/chem.201101768. Epub 2011 Dec 16. PMID: 22179940.
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Microfluidic chips for chirality exploration.

Analytical chemistry

Nagl S, Schulze P, Ohla S, Beyreiss R, Gitlin L, Belder D.
PMID: 21443215
Anal Chem. 2011 May 01;83(9):3232-8. doi: 10.1021/ac200150w. Epub 2011 Mar 28.

Microfluidic chips applied to the investigation of chirality allow reaction, separation and analysis of minuscule amounts of enantiomeric molecules. Chiral chip technology is employed in fields as diverse as pharmaceutical high throughput screening and deep space exploration missions.

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Nagl S, Schulze P, Ohla S, et al. Microfluidic chips for chirality exploration. Anal Chem. 2011;83(9):3232-8doi: 10.1021/ac200150w.
Nagl, S., Schulze, P., Ohla, S., Beyreiss, R., Gitlin, L., & Belder, D. (2011). Microfluidic chips for chirality exploration. Analytical chemistry, 83(9), 3232-8. https://doi.org/10.1021/ac200150w
Nagl, Stefan, et al. "Microfluidic chips for chirality exploration." Analytical chemistry vol. 83,9 (2011): 3232-8. doi: https://doi.org/10.1021/ac200150w
Nagl S, Schulze P, Ohla S, Beyreiss R, Gitlin L, Belder D. Microfluidic chips for chirality exploration. Anal Chem. 2011 May 01;83(9):3232-8. doi: 10.1021/ac200150w. Epub 2011 Mar 28. PMID: 21443215.
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Showing 1 to 7 of 7 entries