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Showing 1 to 7 of 7 entries
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Treatment with Autophagy Inducer Trehalose Alleviates Memory and Behavioral Impairments and Neuroinflammatory Brain Processes in db/db Mice.

Cells

Korolenko TA, Dubrovina NI, Ovsyukova MV, Bgatova NP, Tenditnik MV, Pupyshev AB, Akopyan AA, Goncharova NV, Lin CL, Zavjalov EL, Tikhonova MA, Amstislavskaya TG.
PMID: 34685538
Cells. 2021 Sep 27;10(10). doi: 10.3390/cells10102557.

Autophagy attenuation has been found in neurodegenerative diseases, aging, diabetes mellitus, and atherosclerosis. In experimental models of neurodegenerative diseases, the correction of autophagy in the brain reverses neuronal and behavioral deficits and hence seems to be a promising therapy...

Empagliflozin alleviates podocytopathy and enhances glomerular nephrin expression in .

World journal of diabetes

Klimontov VV, Korbut AI, Taskaeva IS, Bgatova NP, Dashkin MV, Orlov NB, Khotskina AS, Zavyalov EL, Klein T.
PMID: 33384767
World J Diabetes. 2020 Dec 15;11(12):596-610. doi: 10.4239/wjd.v11.i12.596.

BACKGROUND: Modern guidelines recommend sodium-glucose cotransporter-2 (SGLT2) inhibitors as the preferred antihyperglycemic agents for patients with type 2 diabetes and chronic kidney disease. However, the mechanisms underlying the renal protective effect of SGLT2 inhibitors are not fully understood.AIM: To...

Ultrastructure of Endothelial Cells of Myocardial Capillaries in Burn Septicotoxemia.

Bulletin of experimental biology and medicine

Taskaeva YS, Bgatova NP, Savchenko SV, Grebenshchikova AS, Oshchepkova NG, Kuznetsov EV.
PMID: 34297295
Bull Exp Biol Med. 2021 Jul;171(3):393-398. doi: 10.1007/s10517-021-05235-y. Epub 2021 Jul 23.

We studied ultrastructure and vesicular structures in endothelial cells of myocardial micro-vessels in burn patients. Electron microscopy revealed a significant decrease in volume density of vesicular structures in the endotheliocytes of myocardial capillaries in patients with burn septicotoxemia. The...

Fibroblast Growth Factor 21 (FGF21) Administration Sex-Specifically Affects Blood Insulin Levels and Liver Steatosis in Obese .

Cells

Makarova E, Kazantseva A, Dubinina A, Denisova E, Jakovleva T, Balybina N, Bgatova N, Baranov K, Bazhan N.
PMID: 34943946
Cells. 2021 Dec 07;10(12). doi: 10.3390/cells10123440.

FGF21 is a promising candidate for treating obesity, diabetes, and NAFLD; however, some of its pharmacological effects are sex-specific in mice with the

Fibroblast Growth Factor 21 (FGF21) Administration Sex-Specifically Affects Blood Insulin Levels and Liver Steatosis in Obese .

Cells

Makarova E, Kazantseva A, Dubinina A, Denisova E, Jakovleva T, Balybina N, Bgatova N, Baranov K, Bazhan N.
PMID: 34943946
Cells. 2021 Dec 07;10(12). doi: 10.3390/cells10123440.

FGF21 is a promising candidate for treating obesity, diabetes, and NAFLD; however, some of its pharmacological effects are sex-specific in mice with the

[Early renal changes in type 1 diabetes].

Problemy endokrinologii

Bondar IA, Klimontov VV, Nadeyev AP, Bgatova NP.
PMID: 31627648
Probl Endokrinol (Mosk). 2007 Oct 15;53(5):3-8. doi: 10.14341/probl20075353-8.

The relationships between renal structural abnormalities, metabolic, and hemodynamic changes were studied in 35 type diabetic patients with normal creatinine clearance. Sixteen patients had normal urinary albumin excretion (UAE) rates, 17 were microalbuminuric and 2 had proteinuria (0.68 and...

Circulating Wnt1-inducible signaling pathway protein-1 (WISP-1/CCN4) is a novel biomarker of adiposity in subjects with type 2 diabetes.

Journal of cell communication and signaling

Klimontov VV, Bulumbaeva DM, Fazullina ON, Lykov AP, Bgatova NP, Orlov NB, Konenkov VI, Pfeiffer AFH, Pivovarova-Ramich O, Rudovich N.
PMID: 31782053
J Cell Commun Signal. 2020 Mar;14(1):101-109. doi: 10.1007/s12079-019-00536-4. Epub 2019 Nov 28.

BACKGROUND: Wnt1-inducible signaling pathway protein 1, or cellular communication network factor 4 (CCN4), a member of CCN family of secreted, extracellular matrix associated signaling proteins, recently was validated as a novel adipose tissue derived cytokine.OBJECTIVE: To assess the relationships...

Showing 1 to 7 of 7 entries