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Showing 1 to 12 of 43 entries
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Finding the Right Treatment for Achalasia Treatment: Risks, Efficacy, Complications.

Current treatment options in gastroenterology

Moonen A, Boeckxstaens G.
PMID: 27687234
Curr Treat Options Gastroenterol. 2016 Dec;14(4):420-428. doi: 10.1007/s11938-016-0105-z.

OPINION STATEMENT: Achalasia is a primary esophageal motor disorder of the esophagus that is characterized by the absence of esophageal peristalsis and a failure of the lower esophageal sphincter (LES) to relax upon swallowing. The defective relaxation leads to...

Novel method for studying postoperative ileus in mice.

International journal of physiology, pathophysiology and pharmacology

van Bree SH, Nemethova A, van Bovenkamp FS, Gomez-Pinilla P, Elbers L, Di Giovangiulio M, Matteoli G, van Vliet J, Cailotto C, Tanck MW, Boeckxstaens GE.
PMID: 23320135
Int J Physiol Pathophysiol Pharmacol. 2012;4(4):219-27. Epub 2012 Dec 26.

INTRODUCTION: Postoperative ileus (POI) is characterized by a transient inhibition of coordinated motility of the gastrointestinal (GI) tract after abdominal surgery and leads to increased morbidity and prolonged hospitalization. Currently, intestinal manipulation of the intestine is widely used as...

Chronic obstructive pulmonary disease and comorbidities through the eyes of the patient.

Chronic respiratory disease

Boeckxstaens P, Deregt M, Vandesype P, Willems S, Brusselle G, De Sutter A.
PMID: 22848068
Chron Respir Dis. 2012 Aug;9(3):183-91. doi: 10.1177/1479972312452436.

Patient's attitudes and illness beliefs have shown to be of great importance in chronic obstructive pulmonary disease (COPD). As former qualitative research has mainly focused on patients with end-stage COPD, who are recruited within hospital or pulmonary rehabilitation settings,...

Cholinergic Modulation of Type 2 Immune Responses.

Frontiers in immunology

Bosmans G, Shimizu Bassi G, Florens M, Gonzalez-Dominguez E, Matteoli G, Boeckxstaens GE.
PMID: 29312347
Front Immunol. 2017 Dec 19;8:1873. doi: 10.3389/fimmu.2017.01873. eCollection 2017.

In recent years, the bidirectional relationship between the nervous and immune system has become increasingly clear, and its role in both homeostasis and inflammation has been well documented over the years. Since the introduction of the cholinergic anti-inflammatory pathway,...

The link between income inequality and health in Europe, adding strength dimensions of primary care to the equation.

Social science & medicine (1982)

Detollenaere J, Desmarest AS, Boeckxstaens P, Willems S.
PMID: 29471179
Soc Sci Med. 2018 Mar;201:103-110. doi: 10.1016/j.socscimed.2018.01.041. Epub 2018 Feb 03.

Income inequality has been clearly associated with reduced population health. A body of evidence suggests that a strong primary care system may mitigate this negative association. The aim of this study is to assess the strength of the primary...

Association between person-centredness and financially driven postponement of care in European primary care: a cross-sectional multicountry study.

CMAJ open

Detollenaere J, Boeckxstaens P, Willems S.
PMID: 29669737
CMAJ Open. 2018 Apr 18;6(2):E176-E183. doi: 10.9778/cmajo.20170082.

BACKGROUND: Previous research has shown that person-centred care has beneficial effects on several health-related outcomes. We investigated the association between a general practitioner's person-centred attitude and financially driven postponement of care in European countries.METHODS: In this cross-sectional study, data...

Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis.

Cell

De Schepper S, Verheijden S, Aguilera-Lizarraga J, Viola MF, Boesmans W, Stakenborg N, Voytyuk I, Schmidt I, Boeckx B, Dierckx de Casterlé I, Baekelandt V, Gonzalez Dominguez E, Mack M, Depoortere I, De Strooper B, Sprangers B, Himmelreich U, Soenen S, Guilliams M, Vanden Berghe P, Jones E, Lambrechts D, Boeckxstaens G.
PMID: 30682373
Cell. 2019 Jan 24;176(3):676. doi: 10.1016/j.cell.2019.01.010.

No abstract available.

The Emerging Role of Mast Cells in Irritable Bowel Syndrome.

Gastroenterology & hepatology

Boeckxstaens GE.
PMID: 29942225
Gastroenterol Hepatol (N Y). 2018 Apr;14(4):250-252.

No abstract available.

Vagus Nerve Stimulation Promotes Epithelial Proliferation and Controls Colon Monocyte Infiltration During DSS-Induced Colitis.

Frontiers in medicine

Meroni E, Stakenborg N, Gomez-Pinilla PJ, Stakenborg M, Aguilera-Lizarraga J, Florens M, Delfini M, de Simone V, De Hertogh G, Goverse G, Matteoli G, Boeckxstaens GE.
PMID: 34307422
Front Med (Lausanne). 2021 Jul 07;8:694268. doi: 10.3389/fmed.2021.694268. eCollection 2021.

No abstract available.

Niche-specific functional heterogeneity of intestinal resident macrophages.

Gut

Viola MF, Boeckxstaens G.
PMID: 33384336
Gut. 2021 Jul;70(7):1383-1395. doi: 10.1136/gutjnl-2020-323121. Epub 2020 Dec 31.

Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the response to food antigens and bacteria that are...

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Nature genetics

Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S, Voda AI, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M.
PMID: 34741163
Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 05.

Irritable bowel syndrome (IBS) results from disordered brain-gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for UK Biobank and combined identified cases with IBS with independent cohorts. We conducted a...

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Nature genetics

Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S, Voda AI, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M.
PMID: 34741163
Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 05.

Irritable bowel syndrome (IBS) results from disordered brain-gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for UK Biobank and combined identified cases with IBS with independent cohorts. We conducted a...

Showing 1 to 12 of 43 entries