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Showing 1 to 12 of 181 entries
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Surrogate endpoints: a basis for a rational approach.

European journal of clinical pharmacology

Boissel JP, Collet JP, Moleur P, Haugh M.
PMID: 1425885
Eur J Clin Pharmacol. 1992;43(3):235-44. doi: 10.1007/BF02333016.

In clinical trials, the clinical endpoint is often replaced by an intermediate endpoint, known in some instances as a "surrogate" endpoint. The reasons for the substitution are often both practical and financial. At present, no theoretical basis or practical...

[Clinical trials in general practice. The telematics solution].

Therapie

Boissel JP, Alamercery Y, Collet JP, Luciani J, Leizorovicz A.
PMID: 2080485
Therapie. 1990 Nov-Dec;45(6):471-4.

Clinical trials with private practitioners pose a series of specific problems. Among them, the large number of investigators, the scarcity of time that each investigator can allocate to the study, may be eased by using computerized network. The telematic...

X-ray microtomography provides first data about the feeding behaviour of an endangered lizard, the Montserrat galliwasp (Diploglossus montisserrati).

Royal Society open science

Bochaton C, Boistel R, Charles L.
PMID: 27019732
R Soc Open Sci. 2015 Dec 23;2(12):150461. doi: 10.1098/rsos.150461. eCollection 2015 Dec.

Reporting the diet of recently extinct or very rare taxa, only known by a few museum specimens, is challenging. This study uses X-ray microtomography, a non-destructive investigation method, to obtain the first data about feeding behaviours in the Montserrat...

Insight into the durability of plant resistance to aphids from a demo-genetic study of Aphis gossypii in melon crops.

Evolutionary applications

Thomas S, Vanlerberghe-Masutti F, Mistral P, Loiseau A, Boissot N.
PMID: 27330552
Evol Appl. 2016 May 13;9(6):756-68. doi: 10.1111/eva.12382. eCollection 2016 Jul.

Resistance breakdown has been observed following the deployment of plant cultivars resistant to pests. Assessing the durability of a resistance requires long-term experiments at least at a regional scale. We collected such data for melon resistance conferred by the...

Gas phase infrared spectroscopy of selectively prepared ions.

Physical review letters

Lemaire J, Boissel P, Heninger M, Mauclaire G, Bellec G, Mestdagh H, Simon A, Le Caer S, Ortega JM, Glotin F, Maitre P.
PMID: 12513202
Phys Rev Lett. 2002 Dec 30;89(27):273002. doi: 10.1103/PhysRevLett.89.273002. Epub 2002 Dec 18.

The first example of direct structural characterization of polyaromatic ions by coupling a Fourier transform ion cyclotron resonance mass spectrometer with an infrared free-electron laser is presented. Measurement of the IR spectra of selectively prepared ionic reactive intermediates is...

[The genesis of cardiac activity studied using intracellular microelectrodes].

Journal de physiologie

Coraboeuf E, Distel R, Boistel J.
PMID: 13192668
J Physiol (Paris). 1954;46(1):309-14.

No abstract available.

Mixed transfer function and transport of intensity approach for phase retrieval in the Fresnel region.

Optics letters

Guigay JP, Langer M, Boistel R, Cloetens P.
PMID: 17572724
Opt Lett. 2007 Jun 15;32(12):1617-9. doi: 10.1364/ol.32.001617.

We present a method for phase retrieval in propagation-based x-ray imaging, based on the contrast transfer and transport of intensity equation approaches. We show that the contrast transfer model does not coincide with the transport of intensity in the...

Complications to optical measurements using a laser with an unstable resonator: a case study on laser-induced incandescence of soot.

Applied optics

Dansson MA, Boisselle M, Linne MA, Michelsen HA.
PMID: 18026549
Appl Opt. 2007 Nov 20;46(33):8095-103. doi: 10.1364/ao.46.008095.

Temporal behavior of pulses from a Q-switched Nd:YAG laser with an unstable resonator can vary significantly with radial position in the beam. Our laser provides pulses with position-dependent durations spanning 8-11.5 ns at 1064 nm and 7-10 ns at...

Percutaneous coronary interventions in Europe 1992-2003.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

Cook S, Togni M, Walpoth N, Maier W, Muehlberger V, Legrand V, Milicic D, Zambartas C, Zelizko M, Madsen JK, van Buuren F, Lòpez-Palop R, Peeba M, Koskenkorva J, Vanhanen H, Lablanche JM, Lazaris I, Géza F, Eyjolfsson K, Kearney P, Piscione F, Erglis A, Navickas R, Beissel J, Channam R, Koch K, Deleanu D, Melberg T, Witkowski A, Pereira H, Reho I, Fridrich V, Zorman D, Nilsson T, Oezmen F, Ludman P, Meier B.
PMID: 19755208
EuroIntervention. 2006 Feb;1(4):374-9.

AIMS: The purpose of this registry is to collect data on trends in interventional cardiology within Europe. Special interest focuses on relative increases and ratios in newer revascularization approaches and its distribution in different regions in Europe. We report...

Spatiotemporal mode structure of nonlinearly coupled drift wave modes.

Physical review. E, Statistical, nonlinear, and soft matter physics

Brandt C, Grulke O, Klinger T, Negrete J, Bousselin G, Brochard F, Bonhomme G, Oldenbürger S.
PMID: 22181526
Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Nov;84(5):056405. doi: 10.1103/PhysRevE.84.056405. Epub 2011 Nov 11.

This paper presents full cross-section measurements of drift waves in the linear magnetized plasma of the Mirabelle device. Drift wave modes are studied in regimes of weakly developed turbulence. The drift wave modes develop azimuthal space-time structures of plasma...

No evidence of widespread mechanical pressure hyperalgesia after experimentally induced central sensitization through skin nociceptors.

Pain reports

Cayrol T, Pitance L, Roussel N, Mouraux A, van den Broeke EN.
PMID: 30706036
Pain Rep. 2018 Oct 18;3(6):e691. doi: 10.1097/PR9.0000000000000691. eCollection 2018 Nov.

INTRODUCTION: An increasing number of clinical studies involving a range of chronic pain conditions report widespread mechanical pressure pain hypersensitivity, which is commonly interpreted as resulting from central sensitization (CS). Secondary hyperalgesia (increased pinprick sensitivity surrounding the site of...

SNP-array lesions in core binding factor acute myeloid leukemia.

Oncotarget

Duployez N, Boudry-Labis E, Roumier C, Boissel N, Petit A, Geffroy S, Helevaut N, Celli-Lebras K, Terré C, Fenneteau O, Cuccuini W, Luquet I, Lapillonne H, Lacombe C, Cornillet P, Ifrah N, Dombret H, Leverger G, Jourdan E, Preudhomme C.
PMID: 29464086
Oncotarget. 2018 Jan 08;9(5):6478-6489. doi: 10.18632/oncotarget.24031. eCollection 2018 Jan 19.

Acute myeloid leukemia (AML) with t(8;21) and inv(16), together referred as core binding factor (CBF)-AML, are recognized as unique entities. Both rearrangements share a common pathophysiology, the disruption of the CBF, and a relatively good prognosis. Experiments have demonstrated...

Showing 1 to 12 of 181 entries