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Showing 1 to 12 of 28 entries
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An FT-IRRAS study of nitrophenyl mono- and multilayers electro-deposited on gold by reduction of the diazonium salt.

Physical chemistry chemical physics : PCCP

Ricci A, Bonazzola C, Calvo EJ.
PMID: 16986072
Phys Chem Chem Phys. 2006 Oct 07;8(37):4297-9. doi: 10.1039/b609497j. Epub 2006 Aug 24.

Formation of an organometallic junction by direct bonding of 4-nitrobenzene monolayer on gold surface by diazonium chemistry has been demonstrated by Fourier transform reflection-absorption spectroscopy with s- and p-polarized radiation.

Validation of a dendron concept to tune colloidal stability, MRI relaxivity and bioelimination of functional nanoparticles.

Journal of materials chemistry. B

Walter A, Garofalo A, Parat A, Jouhannaud J, Pourroy G, Voirin E, Laurent S, Bonazza P, Taleb J, Billotey C, Vander Elst L, Muller RN, Begin-Colin S, Felder-Flesch D.
PMID: 32262421
J Mater Chem B. 2015 Feb 28;3(8):1484-1494. doi: 10.1039/c4tb01954g. Epub 2015 Jan 23.

The functionalization of spherical superparamagnetic iron oxide nanoparticles (SPION) of 10 nm with a linear monophosphonate (L1) and also PEGylated mono-phosphonated dendrons of growing generation (D2-G1, -G2 and -G3) yielded dendritic nano-objects of 15 to 30 nm in size,...

DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo.

Gynecologic oncology

Tymon-Rosario J, Bonazzoli E, Bellone S, Manzano A, Pelligra S, Guglielmi A, Gnutti B, Nagarkatti N, Zeybek B, Manara P, Zammataro L, Harold J, Mauricio D, Buza N, Hui P, Altwerger G, Menderes G, Ratner E, Clark M, Andikyan V, Huang GS, Silasi DA, Azodi M, Schwartz PE, Santin AD.
PMID: 34452746
Gynecol Oncol. 2021 Nov;163(2):334-341. doi: 10.1016/j.ygyno.2021.08.014. Epub 2021 Aug 25.

OBJECTIVE: Uterine serous carcinoma (USC) is an aggressive histologic variant of endometrial cancer which portends a poor prognosis. DHES0815A is a novel antibody-drug-conjugate (ADC) which binds specifically to HER2 overexpressing tumors at a distinct epitope from that bound by...

Resonant Raman spectroscopy of PAH--Os self-assembled multilayers.

The Journal of chemical physics

Tognalli N, Fainstein A, Bonazzola C, Calvo E.
PMID: 15268324
J Chem Phys. 2004 Jan 22;120(4):1905-11. doi: 10.1063/1.1635806.

We present a resonant Raman scattering study of (PAH--Os/PVS)n and (PAH--Os/GOx)m self-assembled multilayers (n=1-11 and m=1-3). These Os polymer multilayers can be used in electrodes as efficient molecular wires for biomolecular recognition. The Raman intensity dependence on the number...

Author Correction: Space lidar observations constrain longwave cloud feedback.

Scientific reports

de Guélis TV, Chepfer H, Guzman R, Bonazzola M, Winker DM, Noel V.
PMID: 33024219
Sci Rep. 2020 Oct 07;10(1):16964. doi: 10.1038/s41598-020-74323-2.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Angiotensin II type 1 receptor is involved in hypertension and vascular alterations caused by environmental toxicant hexachlorobenzene.

Toxicology reports

Romero Caimi G, Gorzalczany S, Bonazzola P, Deza Z, Rosón MI, Alvarez L, Castilla R.
PMID: 34522623
Toxicol Rep. 2021 Aug 31;8:1599-1606. doi: 10.1016/j.toxrep.2021.08.009. eCollection 2021.

Environmental hexachlorobenzene (HCB) increases blood pressure (BP) in female rats, causing alterations in arterial structure and function. Here we study the role of Angiotensin II receptor type 1 (AT1) in HCB-induced hypertension through the use of AT1 antagonist losartan....

A phase 2 evaluation of pembrolizumab for recurrent Lynch-like versus sporadic endometrial cancers with microsatellite instability.

Cancer

Bellone S, Roque DM, Siegel ER, Buza N, Hui P, Bonazzoli E, Guglielmi A, Zammataro L, Nagarkatti N, Zaidi S, Lee J, Silasi DA, Huang GS, Andikyan V, Damast S, Clark M, Azodi M, Schwartz PE, Tymon-Rosario JR, Harold JA, Mauricio D, Zeybek B, Menderes G, Altwerger G, Ratner E, Alexandrov LB, Iwasaki A, Kong Y, Song E, Dong W, Elvin JA, Choi J, Santin AD.
PMID: 34875107
Cancer. 2021 Dec 07; doi: 10.1002/cncr.34025. Epub 2021 Dec 07.

BACKGROUND: Microsatellite instability-high (MSI-H)/mismatch repair deficiency (dMMR) is a biomarker for responses to immune checkpoint inhibitors (ICIs). Whether mechanisms underlying microsatellite instability alter responses to ICIs is unclear. This article reports data from a prospective phase 2 pilot study...

Exploiting the GTEx resources to decipher the mechanisms at GWAS loci.

Genome biology

Barbeira AN, Bonazzola R, Gamazon ER, Liang Y, Park Y, Kim-Hellmuth S, Wang G, Jiang Z, Zhou D, Hormozdiari F, Liu B, Rao A, Hamel AR, Pividori MD, Aguet F, Bastarache L, Jordan DM, Verbanck M, Do R, Stephens M, Ardlie K, McCarthy M, Montgomery SB, Segrè AV, Brown CD, Lappalainen T, Wen X, Im HK.
PMID: 33499903
Genome Biol. 2021 Jan 26;22(1):49. doi: 10.1186/s13059-020-02252-4.

The resources generated by the GTEx consortium offer unprecedented opportunities to advance our understanding of the biology of human diseases. Here, we present an in-depth examination of the phenotypic consequences of transcriptome regulation and a blueprint for the functional...

DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo.

Gynecologic oncology

Tymon-Rosario J, Bonazzoli E, Bellone S, Manzano A, Pelligra S, Guglielmi A, Gnutti B, Nagarkatti N, Zeybek B, Manara P, Zammataro L, Harold J, Mauricio D, Buza N, Hui P, Altwerger G, Menderes G, Ratner E, Clark M, Andikyan V, Huang GS, Silasi DA, Azodi M, Schwartz PE, Santin AD.
PMID: 34452746
Gynecol Oncol. 2021 Nov;163(2):334-341. doi: 10.1016/j.ygyno.2021.08.014. Epub 2021 Aug 25.

OBJECTIVE: Uterine serous carcinoma (USC) is an aggressive histologic variant of endometrial cancer which portends a poor prognosis. DHES0815A is a novel antibody-drug-conjugate (ADC) which binds specifically to HER2 overexpressing tumors at a distinct epitope from that bound by...

High weekly doses of liposomal amphotericin B as secondary prophylaxis after cerebral aspergillosis in a paediatric patient.

Medical mycology case reports

Brazzola P, Rossi MR.
PMID: 24567890
Med Mycol Case Rep. 2013 Nov 06;3:1-3. doi: 10.1016/j.mmcr.2013.10.003. eCollection 2014 Jan.

A paediatric patient treated for acute lymphoblastic leukaemia developed cerebral abscesses caused by Aspergillus fumigatus. After surgical draining voriconazole treatment was started. The patient developed a Steven-Johnson syndrome and treatment was switched to L-AmB. The patient developed no new...

Socioeconomic Status and Childhood Leukemia Incidence in Switzerland.

Frontiers in oncology

Adam M, Kuehni CE, Spoerri A, Schmidlin K, Gumy-Pause F, Brazzola P, Probst-Hensch N, Zwahlen M.
PMID: 26175964
Front Oncol. 2015 Jun 30;5:139. doi: 10.3389/fonc.2015.00139. eCollection 2015.

Socioeconomic status (SES) discrepancies exist for child and adult cancer morbidity and are a major public health concern. In this Swiss population-based matched case-control study on the etiology of childhood leukemia, we selected the cases from the Swiss Childhood...

Radiolabeled dendritic probes as tools for high in vivo tumor targeting: application to melanoma.

Journal of materials chemistry. B

Parat A, Kryza D, Degoul F, Taleb J, Viallard C, Janier M, Garofalo A, Bonazza P, Heinrich-Balard L, Cohen R, Miot-Noirault E, Chezal JM, Billotey C, Felder-Flesch D.
PMID: 32262132
J Mater Chem B. 2015 Mar 28;3(12):2560-2571. doi: 10.1039/c5tb00235d. Epub 2015 Feb 24.

In bioimaging, targeting allows refining the diagnosis by improving the sensitivity and especially the specificity for an earlier diagnosis. Two

Showing 1 to 12 of 28 entries