Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 1 of 1 entries
Sorted by: Best Match Show Resources per page
Dopaminergic mechanisms underlying the expression of antipsychotic-induced dopamine supersensitivity in rats.

Neuropharmacology

Servonnet A, Allain F, Gravel-Chouinard A, Hernandez G, Bourdeau Caporuscio C, Legrix M, Lévesque D, Rompré PP, Samaha AN.
PMID: 34364897
Neuropharmacology. 2021 Oct 01;197:108747. doi: 10.1016/j.neuropharm.2021.108747. Epub 2021 Aug 05.

Antipsychotic treatment can produce a dopamine-supersensitive state, potentiating the response to dopamine receptor stimulation. In both schizophrenia patients and rats, this is linked to tolerance to ongoing antipsychotic treatment. In rodents, dopamine supersensitivity is often confirmed by an exaggerated...

Showing 1 to 1 of 1 entries