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Editorial.

Bioorganic & medicinal chemistry letters

Boger DL.
PMID: 26343827
Bioorg Med Chem Lett. 2015 Nov 01;25(21):4713. doi: 10.1016/j.bmcl.2015.08.082. Epub 2015 Sep 01.

No abstract available.

Synthesis of Polymerizable Cyclodextrin Derivatives for Use in Adhesion-Promoting Monomer Formulations.

Journal of research of the National Institute of Standards and Technology

Bowen RL, Carey CM, Flynn KM, Guttman CM.
PMID: 27504209
J Res Natl Inst Stand Technol. 2009 Feb 01;114(1):1-9. doi: 10.6028/jres.114.001. Print 2009.

The synthesis of the cyclodextrin derivatives reported herein was assisted by extensive literature research together with structure-property relationships derived from three-dimensional molecular modeling. These studies led to the hypothesis that many of the 21 hydroxyl groups on beta-cyclodextrin molecules...

A second trigeminal CGRP receptor: function and expression of the AMY1 receptor.

Annals of clinical and translational neurology

Walker CS, Eftekhari S, Bower RL, Wilderman A, Insel PA, Edvinsson L, Waldvogel HJ, Jamaluddin MA, Russo AF, Hay DL.
PMID: 26125036
Ann Clin Transl Neurol. 2015 Jun;2(6):595-608. doi: 10.1002/acn3.197. Epub 2015 Apr 01.

OBJECTIVE: The trigeminovascular system plays a central role in migraine, a condition in need of new treatments. The neuropeptide, calcitonin gene-related peptide (CGRP), is proposed as causative in migraine and is the subject of intensive drug discovery efforts. This...

Diagnosis of an imprinted-gene syndrome by a novel bioinformatics analysis of whole-genome sequences from a family trio.

Molecular genetics & genomic medicine

Bodian DL, Solomon BD, Khromykh A, Thach DC, Iyer RK, Link K, Baker RL, Baveja R, Vockley JG, Niederhuber JE.
PMID: 25614875
Mol Genet Genomic Med. 2014 Nov;2(6):530-8. doi: 10.1002/mgg3.107. Epub 2014 Aug 26.

Whole-genome sequencing and whole-exome sequencing are becoming more widely applied in clinical medicine to help diagnose rare genetic diseases. Identification of the underlying causative mutations by genome-wide sequencing is greatly facilitated by concurrent analysis of multiple family members, most...

Corrigendum: High-throughput discovery of novel developmental phenotypes.

Nature

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie Helmut Fuchs SM, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Nutter SNLMJ, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, Wurst W, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SDM, Adams DJ, Lloyd KCK, McKerlie C, Beaudet AL, Murray MBSA.
PMID: 29144450
Nature. 2017 Nov 16;551(7680):398. doi: 10.1038/nature24643. Epub 2017 Nov 08.

This corrects the article DOI: 10.1038/nature19356.

Toxicity evaluation of trap and skeet shooting targets to aquatic test species.

Ecotoxicology (London, England)

Baer KN, Hutton DG, Boeri RL, Ward TJ, Stahl RG.
PMID: 24197831
Ecotoxicology. 1995 Dec;4(6):385-92. doi: 10.1007/BF00118873.

: Large quantities of trap and skeet clay targets are used in shooting activities around the United States. For example, the number of targets used since 1970 has averaged approximately 560 million a year. A number of acute and...

The primary health care physician and the cancer patient: tips and strategies for managing sexual health.

Translational andrology and urology

Zhou ES, Nekhlyudov L, Bober SL.
PMID: 26816826
Transl Androl Urol. 2015 Apr;4(2):218-31. doi: 10.3978/j.issn.2223-4683.2014.11.07.

There is a large and growing population of long-term cancer survivors. Primary care physicians (PCPs) are playing an increasingly greater role in the care of these patients across the continuum of cancer survivorship. In this role, PCPs are faced...

Total Synthesis of Quinoxapeptin A-C: Establishment of Absolute Stereochemistry.

Angewandte Chemie (International ed. in English)

Boger DL, Ledeboer MW, Kume M, Jin Q.
PMID: 10458810
Angew Chem Int Ed Engl. 1999 Aug;38(16):2424-2426. doi: 10.1002/(sici)1521-3773(19990816)38:16<2424::aid-anie2424>3.0.co;2-9.

The relative and absolute stereochemistry of the naturally occurring potent HIV reverse transcriptase (RT) inhibitors 1 and 2, quinoxapeptin A and B, were established by total synthesis. Their synthetic precursor 3 (dubbed quinoxapeptin C) was found to be a...

A Synthesis of What We Know About the Use of Physical Restraints and Seclusion with Patients in Psychiatric and Acute Care Settings.

The online journal of knowledge synthesis for nursing

Bower FL, McCullough CS, Timmons ME.
PMID: 12489033
Online J Knowl Synth Nurs. 2000 Jan 19;7:2.

PURPOSE: This article synthesizes research findings on the use of restraint and seclusion with patients in psychiatric and acute care settings. CONCLUSIONS: The little that is known about restraint/seclusion use with these populations is inconsistent. Attitudes and perceptions of...

Are the Duocarmycin and CC-1065 DNA Alkylation Reactions Acid-Catalyzed? Solvolysis pH-Rate Profiles Suggest They Are Not.

The Journal of organic chemistry

Boger DL, Garbaccio RM.
PMID: 11674637
J Org Chem. 1999 Jul 23;64(15):5666-5669. doi: 10.1021/jo990762g.

A study of the solvolysis pH-rate profiles for two key reactive CC-1065/duocarmycin alkylation subunit analogues is detailed. Unlike the authentic alkylation subunits and N-BOC-CBI (4) which are too stable to establish complete solvolysis pH-rate profiles, the analogues N-BOC-CBQ (5)...

Gone with the wind: the origin of S0 galaxies in clusters.

Science (New York, N.Y.)

Quilis V, Moore B, Bower R.
PMID: 10834835
Science. 2000 Jun 02;288(5471):1617-20. doi: 10.1126/science.288.5471.1617.

We present three-dimensional, high-resolution hydrodynamical simulations of the interaction between the hot ionized intracluster medium and the cold interstellar medium of spiral galaxies. Ram pressure and turbulent/viscous stripping remove 100% of the atomic hydrogen content of luminous galaxies like...

CC-1065 and the Duocarmycins: Synthetic Studies.

Chemical reviews

Boger DL, Boyce CW, Garbaccio RM, Goldberg JA.
PMID: 11848889
Chem Rev. 1997 May 08;97(3):787-828. doi: 10.1021/cr960095g.

No abstract available.

Showing 1 to 12 of 193 entries