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Showing 1 to 12 of 95 entries
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Optimization of HIV-1 Envelope DNA Vaccine Candidates within Three Different Animal Models, Guinea Pigs, Rabbits and Cynomolgus Macaques.

Vaccines

Borggren M, Vinner L, Andresen BS, Grevstad B, Repits J, Melchers M, Elvang TL, Sanders RW, Martinon F, Dereuddre-Bosquet N, Bowles EJ, Stewart-Jones G, Biswas P, Scarlatti G, Jansson M, Heyndrickx L, Grand RL, Fomsgaard A.
PMID: 26344115
Vaccines (Basel). 2013 Jul 19;1(3):305-27. doi: 10.3390/vaccines1030305.

HIV-1 DNA vaccines have many advantageous features. Evaluation of HIV-1 vaccine candidates often starts in small animal models before macaque and human trials. Here, we selected and optimized DNA vaccine candidates through systematic testing in rabbits for the induction...

Next generation sequencing-based copy number analysis reveals low prevalence of deletions and duplications in 46 genes associated with genetic cardiomyopathies.

Molecular genetics & genomic medicine

Ceyhan-Birsoy O, Pugh TJ, Bowser MJ, Hynes E, Frisella AL, Mahanta LM, Lebo MS, Amr SS, Funke BH.
PMID: 27066507
Mol Genet Genomic Med. 2015 Dec 16;4(2):143-51. doi: 10.1002/mgg3.187. eCollection 2016 Mar.

BACKGROUND: Diagnostic testing for genetic cardiomyopathies has undergone dramatic changes in the last decade with next generation sequencing (NGS) expanding the number of genes that can be interrogated simultaneously. Exon resolution copy number analysis is increasingly incorporated into routine...

Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis.

Frontiers in cellular neuroscience

Crowley T, Fitzpatrick JM, Kuijper T, Cryan JF, O'Toole O, O'Leary OF, Downer EJ.
PMID: 26283920
Front Cell Neurosci. 2015 Jul 28;9:284. doi: 10.3389/fncel.2015.00284. eCollection 2015.

The GABAB receptor agonist, baclofen, is used to treat muscle tightness and cramping caused by spasticity in a number of disorders including multiple sclerosis (MS), but its precise mechanism of action is unknown. Neuroinflammation drives the central pathology in...

SUBDURAL HEMATOMA: A STUDY OF ONE HUNDRED FORTY-THREE CASES ENCOUNTERED DURING A FIVE-YEAR PERIOD.

Annals of surgery

Laudig GH, Browder EJ, Watson RA.
PMID: 17857723
Ann Surg. 1941 Feb;113(2):170-91. doi: 10.1097/00000658-194102000-00002.

No abstract available.

Si:P as a laboratory analogue for hydrogen on high magnetic field white dwarf stars.

Nature communications

Murdin BN, Li J, Pang ML, Bowyer ET, Litvinenko KL, Clowes SK, Engelkamp H, Pidgeon CR, Galbraith I, Abrosimov NV, Riemann H, Pavlov SG, Hübers HW, Murdin PG.
PMID: 23403570
Nat Commun. 2013;4:1469. doi: 10.1038/ncomms2466.

Laboratory spectroscopy of atomic hydrogen in a magnetic flux density of 10(5) T (1 gigagauss), the maximum observed on high-field magnetic white dwarfs, is impossible because practically available fields are about a thousand times less. In this regime, the...

Early readmission and length of hospitalization practices in the Dialysis Outcomes and Practice Patterns Study (DOPPS).

Hemodialysis international. International Symposium on Home Hemodialysis

Lopes AA, Leavey SF, McCullough K, Gillespie B, Bommer J, Canaud BJ, Saito A, Fukuhara S, Held PJ, Port FK, Young EW.
PMID: 19379429
Hemodial Int. 2004 Jul 01;8(3):287-94. doi: 10.1111/j.1492-7535.2004.01107.x.

BACKGROUND: Rising hospital care costs have created pressure to shorten hospital stays and emphasize outpatient care. This study tests the hypothesis that shorter median length of stay (LOS) as a dialysis facility practice is associated with higher rates of...

Bacterial Adhesion under Static and Dynamic Conditions.

Applied and environmental microbiology

Rijnaarts HH, Norde W, Bouwer EJ, Lyklema J, Zehnder AJ.
PMID: 16349063
Appl Environ Microbiol. 1993 Oct;59(10):3255-65. doi: 10.1128/aem.59.10.3255-3265.1993.

The deposition of various pseudomonads and coryneform bacteria with different hydrophobicities (water contact angles) and negative cell surface charges on negatively charged Teflon and glass surfaces was investigated. The levels of deposition varied between 5.0 x 10 and 1.6...

Exploring the potential of expatriate social networks to reduce HIV and STI transmission: a protocol for a qualitative study.

BMJ open

Crawford G, Bowser NJ, Brown GE, Maycock BR.
PMID: 23444449
BMJ Open. 2013 Feb 26;3(2). doi: 10.1136/bmjopen-2013-002581. Print 2013.

INTRODUCTION: HIV diagnoses acquired among Australian men working or travelling overseas including  Southeast Asia are increasing. This change within transmission dynamics means traditional approaches to prevention need to be considered in new contexts. The significance and role of social...

A risk-mitigation approach to the management of induced seismicity.

Journal of seismology

Bommer JJ, Crowley H, Pinho R.
PMID: 28190961
J Seismol. 2015;19(2):623-646. doi: 10.1007/s10950-015-9478-z. Epub 2015 Feb 04.

Earthquakes may be induced by a wide range of anthropogenic activities such as mining, fluid injection and extraction, and hydraulic fracturing. In recent years, the increased occurrence of induced seismicity and the impact of some of these earthquakes on...

Measurements of Rural Sulfur Dioxide and Particle Sulfate: Analysis of CASTNet Data, 1987 through 1996.

Journal of the Air & Waste Management Association (1995)

Baumgardner RE, Isil SS, Bowser JJ, Fitzgerald KM.
PMID: 28072371
J Air Waste Manag Assoc. 1999 Nov;49(11):1266-1279. doi: 10.1080/10473289.1999.10463966.

The Clean Air Status and Trends Network (CASTNet) was implemented by the U.S. Environmental Protection Agency (EPA) in 1991 in response to Title IX of the Clean Air Amendments of 1990, which mandated the deployment of a national ambient...

Characterisation of ground motion recording stations in the Groningen gas field.

Journal of seismology

Noorlandt R, Kruiver PP, de Kleine MPE, Karaoulis M, de Lange G, Di Matteo A, von Ketelhodt J, Ruigrok E, Edwards B, Rodriguez-Marek A, Bommer JJ, van Elk J, Doornhof D.
PMID: 29755286
J Seismol. 2018;22(3):605-623. doi: 10.1007/s10950-017-9725-6. Epub 2018 Jan 03.

The seismic hazard and risk analysis for the onshore Groningen gas field requires information about local soil properties, in particular shear-wave velocity (

The crisis of health care in Myanmar.

Lancet (London, England)

Bowyer JJ, Broster SC, Halbert J, Oo SS, Rubin SP.
PMID: 33721565
Lancet. 2021 Mar 27;397(10280):1182. doi: 10.1016/S0140-6736(21)00621-8. Epub 2021 Mar 12.

No abstract available.

Showing 1 to 12 of 95 entries