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Showing 1 to 12 of 65 entries
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Germline whole exome sequencing and large-scale replication identifies .

Oncotarget

Dicks E, Song H, Ramus SJ, Oudenhove EV, Tyrer JP, Intermaggio MP, Kar S, Harrington P, Bowtell DD, Group AS, Cicek MS, Cunningham JM, Fridley BL, Alsop J, Jimenez-Linan M, Piskorz A, Goranova T, Kent E, Siddiqui N, Paul J, Crawford R, Poblete S, Lele S, Sucheston-Campbell L, Moysich KB, Sieh W, McGuire V, Lester J, Odunsi K, Whittemore AS, Bogdanova N, Dürst M, Hillemanns P, Karlan BY, Gentry-Maharaj A, Menon U, Tischkowitz M, Levine D, Brenton JD, Dörk T, Goode EL, Gayther SA, Pharoah DPP.
PMID: 28881617
Oncotarget. 2017 Mar 03;8(31):50930-50940. doi: 10.18632/oncotarget.15871. eCollection 2017 Aug 01.

We analyzed whole exome sequencing data in germline DNA from 412 high grade serous ovarian cancer (HGSOC) cases from The Cancer Genome Atlas Project and identified 5,517 genes harboring a predicted deleterious germline coding mutation in at least one...

Imaging the long-range dipolar field in structured liquid state samples.

Journal of magnetic resonance (San Diego, Calif. : 1997)

Bowtell R, Gutteridge S, Ramanathan C.
PMID: 11384173
J Magn Reson. 2001 Jun;150(2):147-55. doi: 10.1006/jmre.2001.2323.

We describe imaging experiments in which the pattern of the dipolar field generated by spatially modulated nuclear magnetization is directly visualized in simply structured phantoms. Two types of experiment have been carried out at 11.7 T using (1)H NMR...

Structural Investigations with the Dipolar Demagnetizing Field in Solution NMR.

Physical review letters

Bowtell R, Robyr P.
PMID: 10061426
Phys Rev Lett. 1996 Jun 24;76(26):4971-4974. doi: 10.1103/PhysRevLett.76.4971.

No abstract available.

Supported self-management for cancer survivors to address long-term biopsychosocial consequences of cancer and treatment to optimize living well.

Current opinion in supportive and palliative care

Howell DD.
PMID: 29315091
Curr Opin Support Palliat Care. 2018 Mar;12(1):92-99. doi: 10.1097/SPC.0000000000000329.

PURPOSE OF REVIEW: As individuals are living longer with cancer as a chronic disease, they face new health challenges that require the application of self-management behaviors and skills that may not be in their usual repertoire of self-regulatory health...

Modulating Brain Networks With Transcranial Magnetic Stimulation Over the Primary Motor Cortex: A Concurrent TMS/fMRI Study.

Frontiers in human neuroscience

Jung J, Bungert A, Bowtell R, Jackson SR.
PMID: 32116612
Front Hum Neurosci. 2020 Feb 14;14:31. doi: 10.3389/fnhum.2020.00031. eCollection 2020.

Stimulating the primary motor cortex (M1) using transcranial magnetic stimulation (TMS) causes unique multisensory experience such as the targeted muscle activity, afferent/reafferent sensory feedback, tactile sensation over the scalp and "click" sound. Although the human M1 has been intensively...

Acquired .

Cancer research

Nesic K, Kondrashova O, Hurley RM, McGehee CD, Vandenberg CJ, Ho GY, Lieschke E, Dall G, Bound N, Shield-Artin K, Radke M, Musafer A, Chai ZQ, Ghamsari MRE, Harrell MI, Kee D, Olesen I, McNally O, Traficante N, Australian Ovarian Cancer Study, DeFazio A, Bowtell DDL, Swisher EM, Weroha SJ, Nones K, Waddell N, Kaufmann SH, Dobrovic A, Wakefield MJ, Scott CL.
PMID: 34321239
Cancer Res. 2021 Sep 15;81(18):4709-4722. doi: 10.1158/0008-5472.CAN-21-0774. Epub 2021 Jul 28.

In high-grade serous ovarian carcinoma (HGSC), deleterious mutations in DNA repair gene

Use, Practices and Attitudes of Elite and Sub-Elite Athletes towards Tart Cherry Supplementation.

Sports (Basel, Switzerland)

Wangdi JT, Sabou V, O'Leary MF, Kelly VG, Bowtell JL.
PMID: 33807198
Sports (Basel). 2021 Mar 31;9(4). doi: 10.3390/sports9040049.

Tart cherry (TC) supplementation can improve exercise recovery and performance; and may also improve sleep duration and quality. This study investigated the use and knowledge of TC supplementation by athletes of all competitive levels. Eighty participants (52.5% elite (international,...

Synergistic targeting of BRCA1 mutated breast cancers with PARP and CDK2 inhibition.

NPJ breast cancer

Aziz D, Portman N, Fernandez KJ, Lee C, Alexandrou S, Llop-Guevara A, Phan Z, Yong A, Wilkinson A, Sergio CM, Ferraro D, Etemadmoghadam D, Bowtell DD, Serra V, Waring P, Lim E, Caldon CE.
PMID: 34465787
NPJ Breast Cancer. 2021 Aug 31;7(1):111. doi: 10.1038/s41523-021-00312-x.

Basal-like breast cancers (BLBC) are aggressive breast cancers that respond poorly to targeted therapies and chemotherapies. In order to define therapeutically targetable subsets of BLBC we examined two markers: cyclin E1 and BRCA1 loss. In high grade serous ovarian...

Regional Brain Correlates of Beta Bursts in Health and Psychosis: A Concurrent Electroencephalography and Functional Magnetic Resonance Imaging Study.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Briley PM, Liddle EB, Simmonite M, Jansen M, White TP, Balain V, Palaniyappan L, Bowtell R, Mullinger KJ, Liddle PF.
PMID: 33495122
Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Dec;6(12):1145-1156. doi: 10.1016/j.bpsc.2020.10.018. Epub 2020 Nov 05.

BACKGROUND: There is emerging evidence for abnormal beta oscillations in psychosis. Beta oscillations are likely to play a key role in the coordination of sensorimotor information that is crucial to healthy mental function. Growing evidence suggests that beta oscillations...

Practical real-time MEG-based neural interfacing with optically pumped magnetometers.

BMC biology

Wittevrongel B, Holmes N, Boto E, Hill R, Rea M, Libert A, Khachatryan E, Van Hulle MM, Bowtell R, Brookes MJ.
PMID: 34376215
BMC Biol. 2021 Aug 10;19(1):158. doi: 10.1186/s12915-021-01073-6.

BACKGROUND: Brain-computer interfaces decode intentions directly from the human brain with the aim to restore lost functionality, control external devices or augment daily experiences. To combine optimal performance with wide applicability, high-quality brain signals should be captured non-invasively. Magnetoencephalography...

Tart Cherry Supplement Enhances Skeletal Muscle Glutathione Peroxidase Expression and Functional Recovery after Muscle Damage.

Medicine and science in sports and exercise

Wangdi JT, O'Leary MF, Kelly VG, Jackman SR, Tang JCY, Dutton J, Bowtell JL.
PMID: 34772901
Med Sci Sports Exerc. 2021 Nov 10; doi: 10.1249/MSS.0000000000002827. Epub 2021 Nov 10.

INTRODUCTION: Montmorency cherry concentrate (MCC) supplementation enhances functional recovery from exercise, potentially due to antioxidant and anti-inflammatory effects. However, to date, supporting empirical evidence for these mechanistic hypotheses is reliant on indirect blood biomarkers. This study is the first...

Management of terminal illness: a medical school-hospice partnership model to teach medical students about end-of-life care.

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

Cowell DD, Farrell C, Campbell NA, Canady BE.
PMID: 12824147
Acad Psychiatry. 2002;26(2):76-81. doi: 10.1176/appi.ap.26.2.76.

Physicians are not only called upon to deal with biological, but also with psychosocial issues and concerns in the treatment of the terminally ill. Their training, however, usually does not prepare them to value palliative care, or help them...

Showing 1 to 12 of 65 entries